BDKRB2 (bradykinin receptor B2) - Rat Genome Database

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Gene: BDKRB2 (bradykinin receptor B2) Chlorocebus sabaeus
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Symbol: BDKRB2
Name: bradykinin receptor B2
RGD ID: 18544225
Description: ENCODES a protein that exhibits beta-2 adrenergic receptor binding (ortholog); bradykinin receptor activity (ortholog); INVOLVED IN acute inflammatory response to antigenic stimulus (ortholog); cellular response to hypoxia (ortholog); intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator (ortholog); PARTICIPATES IN G protein mediated signaling pathway via Galphai family; G protein mediated signaling pathway via Galphaq family; kallikrein-kinin cascade pathway; ASSOCIATED WITH acute kidney failure (ortholog); acute myeloid leukemia (ortholog); Animal Disease Models (ortholog); FOUND IN endosome (inferred); external side of plasma membrane (inferred); Golgi apparatus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: B2 bradykinin receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12474,084,907 - 74,125,604 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2474,118,210 - 74,122,909 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605361,236,289 - 61,276,664 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BDKRB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12474,084,907 - 74,125,604 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2474,118,210 - 74,122,909 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605361,236,289 - 61,276,664 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
BDKRB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381496,204,839 - 96,244,164 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1496,204,679 - 96,244,166 (+)EnsemblGRCh38hg38GRCh38
GRCh371496,671,176 - 96,710,501 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361495,740,950 - 95,780,542 (+)NCBINCBI36Build 36hg18NCBI36
Build 341495,740,949 - 95,780,536NCBI
Celera1476,726,862 - 76,766,386 (+)NCBICelera
Cytogenetic Map14q32.2NCBI
HuRef1476,856,277 - 76,895,774 (+)NCBIHuRef
CHM1_11496,610,085 - 96,649,595 (+)NCBICHM1_1
T2T-CHM13v2.01490,436,088 - 90,475,413 (+)NCBIT2T-CHM13v2.0
Bdkrb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912105,529,431 - 105,561,503 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12105,529,485 - 105,561,496 (+)EnsemblGRCm39 Ensembl
GRCm3812105,563,172 - 105,595,244 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12105,563,226 - 105,595,237 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712106,801,382 - 106,831,281 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612105,964,222 - 105,994,121 (+)NCBIMGSCv36mm8
Celera12106,797,782 - 106,827,683 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1255.76NCBI
Bdkrb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86130,237,055 - 130,267,205 (+)NCBIGRCr8
mRatBN7.26124,472,317 - 124,502,497 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6124,472,566 - 124,502,497 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6124,593,665 - 124,623,640 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06124,888,932 - 124,918,906 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06124,250,138 - 124,280,235 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06129,399,468 - 129,429,676 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6129,399,468 - 129,429,676 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06138,615,812 - 138,622,272 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46129,744,781 - 129,748,851 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16129,748,527 - 129,752,598 (+)NCBI
Celera6122,039,524 - 122,069,422 (+)NCBICelera
RH 3.4 Map6815.41RGD
Cytogenetic Map6q32NCBI
Bdkrb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543816,511,759 - 16,537,172 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543816,514,300 - 16,537,160 (-)NCBIChiLan1.0ChiLan1.0
BDKRB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21597,363,214 - 97,404,173 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11496,579,702 - 96,620,931 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01476,832,833 - 76,873,860 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11496,157,122 - 96,196,253 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1496,156,494 - 96,196,253 (+)Ensemblpanpan1.1panPan2
BDKRB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1864,974,588 - 65,005,682 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl864,974,997 - 65,003,407 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha864,490,876 - 64,519,295 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0865,246,390 - 65,277,067 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl865,246,390 - 65,274,792 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1864,919,488 - 64,947,871 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0864,980,727 - 65,009,155 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0865,304,383 - 65,332,835 (+)NCBIUU_Cfam_GSD_1.0
Bdkrb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086409,528,206 - 9,533,778 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936604548,847 - 549,956 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936604548,844 - 551,031 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BDKRB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7117,438,713 - 117,472,005 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17117,438,622 - 117,472,005 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Bdkrb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247348,513,814 - 8,539,036 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247348,513,601 - 8,538,838 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
68 36 18 34 34 52 20

Sequence


Ensembl Acc Id: ENSCSAT00000008665   ⟹   ENSCSAP00000006812
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2474,118,210 - 74,122,909 (+)Ensembl
RefSeq Acc Id: XM_007987759   ⟹   XP_007985950
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12474,084,907 - 74,123,782 (+)NCBI
Vero_WHO_p1.0NW_02366605361,236,290 - 61,276,664 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007987761   ⟹   XP_007985952
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12474,084,907 - 74,125,604 (+)NCBI
Vero_WHO_p1.0NW_02366605361,236,289 - 61,276,664 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007985950 (Get FASTA)   NCBI Sequence Viewer  
  XP_007985952 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000006812.1
RefSeq Acc Id: XP_007985952   ⟸   XM_007987761
- UniProtKB: A0A0D9RDX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007985950   ⟸   XM_007987759
- UniProtKB: A0A0D9RDX3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000006812   ⟸   ENSCSAT00000008665


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010582 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008665.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro Brdyknn_2_rcpt UniProtKB/TrEMBL
  Brdyknn_rcpt UniProtKB/TrEMBL
  GPCR1 UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
KEGG Report csab:103229642 UniProtKB/TrEMBL
NCBI Gene BDKRB2 ENTREZGENE
PANTHER B2 BRADYKININ RECEPTOR UniProtKB/TrEMBL
  CELL ADHESION MOLECULE UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS BRADYKININR UniProtKB/TrEMBL
  BRADYKINNB2R UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0D9RDX3 ENTREZGENE, UniProtKB/TrEMBL