SFTPC (surfactant protein C) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: SFTPC (surfactant protein C) Chlorocebus sabaeus
Analyze
Symbol: SFTPC
Name: surfactant protein C
RGD ID: 18338387
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); cellular response to nitric oxide (ortholog); circadian rhythm (ortholog); ASSOCIATED WITH adult respiratory distress syndrome (ortholog); asthma (ortholog); bacterial pneumonia (ortholog); FOUND IN alveolar lamellar body (ortholog); cytoplasm (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pulmonary surfactant-associated protein C
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1820,229,756 - 20,233,568 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,230,870 - 20,234,020 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605222,002,517 - 22,009,591 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SFTPC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1820,229,756 - 20,233,568 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,230,870 - 20,234,020 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605222,002,517 - 22,009,591 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SFTPC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38822,157,383 - 22,164,479 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl822,156,913 - 22,164,479 (+)EnsemblGRCh38hg38GRCh38
GRCh37822,014,896 - 22,021,992 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,075,129 - 22,077,937 (+)NCBINCBI36Build 36hg18NCBI36
Build 34822,075,112 - 22,077,928NCBI
Celera820,981,168 - 20,983,976 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef820,561,488 - 20,564,296 (+)NCBIHuRef
CHM1_1822,220,843 - 22,223,651 (+)NCBICHM1_1
T2T-CHM13v2.0822,431,328 - 22,438,424 (+)NCBIT2T-CHM13v2.0
Sftpc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,758,381 - 70,761,521 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,758,389 - 70,761,521 (-)EnsemblGRCm39 Ensembl
GRCm381470,520,941 - 70,524,081 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1470,520,949 - 70,524,081 (-)EnsemblGRCm38mm10GRCm38
MGSCv371470,920,748 - 70,923,888 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361469,256,020 - 69,259,150 (-)NCBIMGSCv36mm8
Celera1468,062,491 - 68,065,631 (-)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.32NCBI
Sftpc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81552,006,274 - 52,009,324 (-)NCBIGRCr8
mRatBN7.21545,596,565 - 45,599,615 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,596,574 - 45,610,777 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1549,714,437 - 49,717,379 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,825,943 - 50,828,885 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,685,234 - 47,688,176 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01552,211,538 - 52,214,480 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1552,211,544 - 52,214,616 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01555,935,055 - 55,937,997 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41550,923,105 - 50,926,047 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11550,938,884 - 50,941,827 (-)NCBI
Celera1545,274,971 - 45,277,913 (-)NCBICelera
Cytogenetic Map15p11NCBI
Sftpc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540345,649,122 - 45,651,837 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540345,649,149 - 45,651,421 (+)NCBIChiLan1.0ChiLan1.0
SFTPC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2740,658,965 - 40,666,346 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,384,149 - 16,391,532 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,402,060 - 21,409,438 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,343,007 - 18,348,764 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,345,940 - 18,348,764 (+)Ensemblpanpan1.1panPan2
SFTPC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12535,088,295 - 35,090,995 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2535,088,279 - 35,091,457 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2535,677,864 - 35,680,614 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02535,299,616 - 35,302,366 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2535,299,694 - 35,302,250 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12535,245,093 - 35,247,843 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02535,099,613 - 35,102,363 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02535,255,134 - 35,257,884 (-)NCBIUU_Cfam_GSD_1.0
Sftpc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494312,588,481 - 12,596,579 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365555,979,417 - 5,982,011 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365555,966,610 - 5,982,083 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SFTPC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl146,440,309 - 6,443,095 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1146,440,309 - 6,443,104 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2146,868,096 - 6,880,564 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sftpc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475817,742,415 - 17,744,655 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475817,742,439 - 17,744,664 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
74 36 17 33 33 58 20

Sequence


Ensembl Acc Id: ENSCSAT00000014640   ⟹   ENSCSAP00000012606
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl820,230,870 - 20,234,020 (+)Ensembl
RefSeq Acc Id: XM_037983686   ⟹   XP_037839614
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605222,002,526 - 22,008,373 (-)NCBI
RefSeq Acc Id: XM_037983687   ⟹   XP_037839615
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605222,002,517 - 22,006,329 (-)NCBI
RefSeq Acc Id: XM_037983688   ⟹   XP_037839616
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605222,002,517 - 22,009,591 (-)NCBI
RefSeq Acc Id: XM_037983689   ⟹   XP_037839617
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605222,002,517 - 22,008,526 (-)NCBI
RefSeq Acc Id: XM_037983690   ⟹   XP_037839618
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605222,002,517 - 22,005,308 (-)NCBI
RefSeq Acc Id: XM_037983691   ⟹   XP_037839619
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605222,002,523 - 22,009,591 (-)NCBI
Ensembl Acc Id: ENSCSAP00000012606   ⟸   ENSCSAT00000014640
RefSeq Acc Id: XP_037839616   ⟸   XM_037983688
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RVG7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037839617   ⟸   XM_037983689
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RVG7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037839615   ⟸   XM_037983687
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RVG7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037839618   ⟸   XM_037983690
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RVG7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037839619   ⟸   XM_037983691
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RVG7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037839614   ⟸   XM_037983686
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016543 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014640.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.390.150 UniProtKB/TrEMBL
InterPro BRICHOS_dom UniProtKB/TrEMBL
  SP-C UniProtKB/TrEMBL
  SP-C_palmitoylation_site UniProtKB/TrEMBL
  Surfactant_protein_propep UniProtKB/TrEMBL
KEGG Report csab:103215445 UniProtKB/TrEMBL
NCBI Gene SFTPC ENTREZGENE
PANTHER PTHR10800 UniProtKB/TrEMBL
  PULMONARY SURFACTANT-ASSOCIATED PROTEIN C UniProtKB/TrEMBL
Pfam BRICHOS UniProtKB/TrEMBL
  SP_C-Propep UniProtKB/TrEMBL
PROSITE BRICHOS UniProtKB/TrEMBL
  SURFACT_PALMITOYL UniProtKB/TrEMBL
SMART BRICHOS UniProtKB/TrEMBL
  SF_P UniProtKB/TrEMBL
UniProt A0A0D9RVG7 ENTREZGENE, UniProtKB/TrEMBL