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Gene: SFTPC (surfactant protein C) Homo sapiens
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Symbol: SFTPC
Name: surfactant protein C
Description: Exhibits identical protein binding activity. Predicted to be involved in cellular protein metabolic process. Predicted to localize to the cytoplasmic vesicle; endoplasmic reticulum membrane; and extracellular region. Implicated in asthma; lung disease (multiple); and respiratory syncytial virus infectious disease. Biomarker of asthma; cystic fibrosis; and lung disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BRICD6; BRICHOS domain containing 6; PSP-C; pulmonary surfactant apoprotein-2 SP-C; pulmonary surfactant-associated protein C; pulmonary surfactant-associated proteolipid SPL(Val); SFTP2; SMDP2; SP-C; SP5
Orthologs:
Mus musculus (house mouse) : Sftpc (surfactant associated protein C)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sftpc (surfactant protein C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sftpc (surfactant protein C)
Pan paniscus (bonobo/pygmy chimpanzee) : SFTPC (surfactant protein C)
Canis lupus familiaris (dog) : SFTPC (surfactant protein C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sftpc (surfactant protein C)
Sus scrofa (pig) : SFTPC (surfactant protein C)
Chlorocebus sabaeus (African green monkey) : SFTPC (surfactant protein C)
Heterocephalus glaber (naked mole-rat) : Sftpc (surfactant protein C)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl822,156,913 - 22,164,479 (+)Ensembl
GRCh38822,161,733 - 22,164,479 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37822,014,853 - 22,021,992 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,075,129 - 22,077,937 (+)NCBINCBI36hg18NCBI36
Build 34822,075,112 - 22,077,928NCBI
Celera820,981,168 - 20,983,976 (+)NCBI
Cytogenetic Map8p21.3NCBI
HuRef820,561,488 - 20,564,296 (+)NCBIHuRef
CHM1_1822,220,843 - 22,223,651 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on SFTPC
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736728
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-01-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.