Gene: Phox2b (paired-like homeobox 2b) Rattus norvegicus
Symbol: Phox2b
Name: paired-like homeobox 2b
Description: ENCODES a protein that exhibits RNA polymerase II proximal promoter sequence-specific DNA binding (ortholog); RNA polymerase II regulatory region sequence-specific DNA binding (ortholog); transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding (ortholog); INVOLVED IN autonomic nervous system development (ortholog); brainstem development (ortholog); cell development (ortholog); ASSOCIATED WITH Congenital Central Hypoventilation Syndrome (ortholog); Crohn Disease (ortholog); Hirschsprung disease ganglioneuroblastoma (ortholog); FOUND IN nucleus; nuclear chromatin (ortholog); nucleoplasm (ortholog); INTERACTS WITH bisphenol A; copper atom; copper(0)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: paired mesoderm homeobox protein 2B; NBPhox; neuroblastoma Phox; paired mesoderm homeobox protein 2B
Homo sapiens (human) : PHOX2B (paired like homeobox 2b)  HGNC  Alliance
Mus musculus (house mouse) : Phox2b (paired-like homeobox 2b)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Phox2b (paired like homeobox 2b)
Pan paniscus (bonobo/pygmy chimpanzee) : PHOX2B (paired like homeobox 2b)
Canis lupus familiaris (dog) : PHOX2B (paired like homeobox 2b)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Phox2b (paired like homeobox 2b)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01442,711,169 - 42,718,707 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01442,510,540 - 42,514,526 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41443,675,180 - 43,677,970 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1440,218,744 - 40,226,258 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Phox2b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560582
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2018-04-10
Status: ACTIVE