| Symbol: |
ADORA2A |
| Name: |
adenosine A2a receptor |
| RGD ID: |
12228090 |
| Description: |
ENCODES a protein that exhibits alpha-actinin binding (ortholog); G protein-coupled adenosine receptor activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); astrocyte activation (ortholog); eating behavior (ortholog); PARTICIPATES IN adenosine signaling pathway; hypoxia inducible factor pathway; ASSOCIATED WITH amphetamine abuse (ortholog); anxiety disorder (ortholog); asthma (ortholog); FOUND IN asymmetric synapse (ortholog); axolemma (ortholog); axon (ortholog) |
| Type: |
protein-coding
|
| RefSeq Status: |
PROVISIONAL |
| Previously known as: |
adenosine receptor A2a |
| RGD Orthologs |
|
| Alliance Orthologs |
|
| More Info |
more info ...
|
| More Info |
|
| Latest Assembly: |
CanFam3.1 - Dog CanFam3.1 Assembly |
| Position: |
| Dog Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| CanFam3.1 | 26 | 28,141,076 - 28,150,600 (+) | NCBI | CanFam3.1 | CanFam3.1 | canFam3 | CanFam3.1 | | CanFam3.1 Ensembl | 26 | 28,141,076 - 28,150,598 (+) | Ensembl | CanFam3.1 | | canFam3 | CanFam3.1 | | Dog10K_Boxer_Tasha | 26 | 27,207,866 - 27,225,894 (+) | NCBI | | Dog10K_Boxer_Tasha | | | | ROS_Cfam_1.0 | 26 | 29,536,347 - 29,554,384 (+) | NCBI | | ROS_Cfam_1.0 | | | | ROS_Cfam_1.0 Ensembl | 26 | 29,534,227 - 29,554,392 (+) | Ensembl | | ROS_Cfam_1.0 Ensembl | | | | UMICH_Zoey_3.1 | 26 | 27,619,698 - 27,637,726 (+) | NCBI | | UMICH_Zoey_3.1 | | | | UNSW_CanFamBas_1.0 | 26 | 27,237,300 - 27,255,320 (+) | NCBI | | UNSW_CanFamBas_1.0 | | | | UU_Cfam_GSD_1.0 | 26 | 28,226,384 - 28,244,417 (+) | NCBI | | UU_Cfam_GSD_1.0 | | |
|
| JBrowse: |
View Region in Genome Browser (JBrowse)
|
| Model |
|
Imported Annotations - SMPDB
Imported Annotations - PID (archival)
Biological Process
| adenylate cyclase-activating G protein-coupled receptor signaling pathway (IBA,IEA,ISO) | apoptotic signaling pathway (IEA) | astrocyte activation (ISO) | | eating behavior (IEA,ISO) | excitatory postsynaptic potential (ISO) | G protein-coupled adenosine receptor signaling pathway (IBA,IEA,ISO) | | G protein-coupled receptor signaling pathway (IEA) | inhibitory postsynaptic potential (IEA) | locomotory behavior (IEA,ISO) | | membrane depolarization (ISO) | negative regulation of alpha-beta T cell activation (IEA) | negative regulation of cell population proliferation (ISO) | | negative regulation of inflammatory response (IEA) | negative regulation of neuron apoptotic process (ISO) | negative regulation of protein kinase activity (ISO) | | negative regulation of vascular permeability (ISO) | neuron projection morphogenesis (ISO) | phospholipase C-activating G protein-coupled receptor signaling pathway (ISO) | | positive regulation of acetylcholine secretion, neurotransmission (ISO) | positive regulation of apoptotic signaling pathway (IEA) | positive regulation of circadian sleep/wake cycle, sleep (ISO) | | positive regulation of ERK1 and ERK2 cascade (ISO) | positive regulation of glutamate secretion (ISO) | positive regulation of long-term synaptic potentiation (ISO) | | positive regulation of protein secretion (ISO) | positive regulation of synaptic transmission, GABAergic (IEA) | positive regulation of synaptic transmission, glutamatergic (ISO) | | positive regulation of urine volume (ISO) | prepulse inhibition (ISO) | presynaptic modulation of chemical synaptic transmission (ISO) | | regulation of calcium ion transport (ISO) | regulation of DNA-templated transcription (ISO) | regulation of mitochondrial membrane potential (ISO) | | regulation of norepinephrine secretion (ISO) | response to alkaloid (ISO) | response to amphetamine (IEA) | | response to caffeine (ISO) | response to purine-containing compound (IEA) | response to xenobiotic stimulus (ISO) | | signal transduction (IEA) | synaptic transmission, cholinergic (ISO) | synaptic transmission, dopaminergic (IEA) | | synaptic transmission, glutamatergic (ISO) | vasodilation (ISO) |
ADORA2A
(Canis lupus familiaris - dog) |
| Dog Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| CanFam3.1 | 26 | 28,141,076 - 28,150,600 (+) | NCBI | CanFam3.1 | CanFam3.1 | canFam3 | CanFam3.1 | | CanFam3.1 Ensembl | 26 | 28,141,076 - 28,150,598 (+) | Ensembl | CanFam3.1 | | canFam3 | CanFam3.1 | | Dog10K_Boxer_Tasha | 26 | 27,207,866 - 27,225,894 (+) | NCBI | | Dog10K_Boxer_Tasha | | | | ROS_Cfam_1.0 | 26 | 29,536,347 - 29,554,384 (+) | NCBI | | ROS_Cfam_1.0 | | | | ROS_Cfam_1.0 Ensembl | 26 | 29,534,227 - 29,554,392 (+) | Ensembl | | ROS_Cfam_1.0 Ensembl | | | | UMICH_Zoey_3.1 | 26 | 27,619,698 - 27,637,726 (+) | NCBI | | UMICH_Zoey_3.1 | | | | UNSW_CanFamBas_1.0 | 26 | 27,237,300 - 27,255,320 (+) | NCBI | | UNSW_CanFamBas_1.0 | | | | UU_Cfam_GSD_1.0 | 26 | 28,226,384 - 28,244,417 (+) | NCBI | | UU_Cfam_GSD_1.0 | | |
|
ADORA2A
(Homo sapiens - human) |
| Human Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| GRCh38 | 22 | 24,423,597 - 24,442,357 (+) | NCBI | GRCh38 | GRCh38 | hg38 | GRCh38 | | GRCh38.p14 Ensembl | 22 | 24,417,879 - 24,442,357 (+) | Ensembl | GRCh38 | | hg38 | GRCh38 | | GRCh37 | 22 | 24,819,565 - 24,838,325 (+) | NCBI | GRCh37 | GRCh37 | hg19 | GRCh37 | | Build 36 | 22 | 23,153,530 - 23,168,325 (+) | NCBI | NCBI36 | Build 36 | hg18 | NCBI36 | | Build 34 | 22 | 23,153,645 - 23,162,878 | NCBI | | | | | | Celera | 22 | 8,623,253 - 8,638,061 (+) | NCBI | | Celera | | | | Cytogenetic Map | 22 | q11.23 | NCBI | | | | | | HuRef | 22 | 7,769,458 - 7,788,241 (+) | NCBI | | HuRef | | | | CHM1_1 | 22 | 24,778,238 - 24,796,999 (+) | NCBI | | CHM1_1 | | | | T2T-CHM13v2.0 | 22 | 24,885,210 - 24,903,991 (+) | NCBI | | T2T-CHM13v2.0 | | |
|
Adora2a
(Mus musculus - house mouse) |
| Mouse Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| GRCm39 | 10 | 75,152,711 - 75,170,626 (+) | NCBI | GRCm39 | GRCm39 | mm39 | | | GRCm39 Ensembl | 10 | 75,152,711 - 75,170,618 (+) | Ensembl | | GRCm39 Ensembl | | | | GRCm38 | 10 | 75,316,877 - 75,334,792 (+) | NCBI | GRCm38 | GRCm38 | mm10 | GRCm38 | | GRCm38.p6 Ensembl | 10 | 75,316,877 - 75,334,784 (+) | Ensembl | GRCm38 | | mm10 | GRCm38 | | MGSCv37 | 10 | 74,779,688 - 74,797,533 (+) | NCBI | GRCm37 | MGSCv37 | mm9 | NCBIm37 | | MGSCv36 | 10 | 74,769,745 - 74,777,652 (+) | NCBI | | MGSCv36 | mm8 | | | Celera | 10 | 76,364,032 - 76,382,114 (+) | NCBI | | Celera | | | | Cytogenetic Map | 10 | C1 | NCBI | | | | | | cM Map | 10 | 38.52 | NCBI | | | | |
|
Adora2a
(Rattus norvegicus - Norway rat) |
| Rat Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| GRCr8 | 20 | 13,315,270 - 13,332,802 (-) | NCBI | | GRCr8 | | | | mRatBN7.2 | 20 | 13,315,848 - 13,333,386 (-) | NCBI | mRatBN7.2 | mRatBN7.2 | | | | mRatBN7.2 Ensembl | 20 | 13,315,853 - 13,333,386 (-) | Ensembl | | mRatBN7.2 Ensembl | | | | UTH_Rnor_SHR_Utx | 20 | 14,022,398 - 14,039,933 (-) | NCBI | Rnor_SHR | UTH_Rnor_SHR_Utx | | | | UTH_Rnor_SHRSP_BbbUtx_1.0 | 20 | 13,383,344 - 13,400,756 (-) | NCBI | Rnor_SHRSP | UTH_Rnor_SHRSP_BbbUtx_1.0 | | | | UTH_Rnor_WKY_Bbb_1.0 | 20 | 13,855,867 - 13,873,399 (-) | NCBI | Rnor_WKY | UTH_Rnor_WKY_Bbb_1.0 | | | | Rnor_6.0 | 20 | 14,265,251 - 14,282,873 (-) | NCBI | Rnor6.0 | Rnor_6.0 | rn6 | Rnor6.0 | | Rnor_6.0 Ensembl | 20 | 14,265,252 - 14,282,873 (-) | Ensembl | Rnor6.0 | | rn6 | Rnor6.0 | | Rnor_5.0 | 20 | 16,449,385 - 16,466,147 (-) | NCBI | Rnor5.0 | Rnor_5.0 | rn5 | Rnor5.0 | | RGSC_v3.4 | 20 | 13,815,719 - 13,834,131 (-) | NCBI | RGSC3.4 | RGSC_v3.4 | rn4 | RGSC3.4 | | RGSC_v3.1 | 20 | 13,815,944 - 13,825,845 (-) | NCBI | | | | | | Celera | 20 | 14,801,379 - 14,818,841 (-) | NCBI | | Celera | | | | Cytogenetic Map | 20 | p12 | NCBI | | | | |
|
Adora2a
(Chinchilla lanigera - long-tailed chinchilla) |
| Chinchilla Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| ChiLan1.0 Ensembl | NW_004955455 | 7,895,974 - 7,906,505 (+) | Ensembl | ChiLan1.0 | | | | | ChiLan1.0 | NW_004955455 | 7,886,720 - 7,906,214 (+) | NCBI | ChiLan1.0 | ChiLan1.0 | | |
|
ADORA2A
(Pan paniscus - bonobo/pygmy chimpanzee) |
| Bonobo Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| NHGRI_mPanPan1-v2 | 23 | 34,212,582 - 34,231,247 (+) | NCBI | | NHGRI_mPanPan1-v2 | | | | NHGRI_mPanPan1 | 22 | 36,943,248 - 36,961,861 (+) | NCBI | | NHGRI_mPanPan1 | | | | Mhudiblu_PPA_v0 | 22 | 5,233,876 - 5,248,622 (+) | NCBI | Mhudiblu_PPA_v0 | Mhudiblu_PPA_v0 | panPan3 | | | PanPan1.1 | 22 | 22,099,404 - 22,114,189 (+) | NCBI | panpan1.1 | PanPan1.1 | panPan2 | | | PanPan1.1 Ensembl | 22 | 22,104,253 - 22,114,189 (+) | Ensembl | panpan1.1 | | panPan2 | |
|
Adora2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
ADORA2A
(Sus scrofa - pig) |
| Pig Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| Sscrofa11.1 Ensembl | 14 | 49,468,877 - 49,485,850 (+) | Ensembl | Sscrofa11.1 | | susScr11 | Sscrofa11.1 | | Sscrofa11.1 | 14 | 49,467,186 - 49,485,845 (+) | NCBI | Sscrofa11.1 | Sscrofa11.1 | susScr11 | Sscrofa11.1 | | Sscrofa10.2 | 14 | 52,914,635 - 52,931,654 (+) | NCBI | Sscrofa10.2 | Sscrofa10.2 | susScr3 | |
|
ADORA2A
(Chlorocebus sabaeus - green monkey) |
| Green Monkey Assembly | Chr | Position (strand) | Source | Genome Browsers |
|---|
| JBrowse | NCBI | UCSC | Ensembl |
|---|
| ChlSab1.1 | 19 | 7,691,678 - 7,706,781 (-) | NCBI | ChlSab1.1 | ChlSab1.1 | chlSab2 | | | ChlSab1.1 Ensembl | 19 | 7,691,536 - 7,706,926 (-) | Ensembl | ChlSab1.1 | ChlSab1.1 Ensembl | chlSab2 | | | Vero_WHO_p1.0 | NW_023666085 | 4,894,557 - 4,913,637 (-) | NCBI | Vero_WHO_p1.0 | Vero_WHO_p1.0 | | |
|
Adora2a
(Heterocephalus glaber - naked mole-rat) |
|
.
|
alimentary part of gastrointestinal system
| | | | | | | | | | | | | |
|---|
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6
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5
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5
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23
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22
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16
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6
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6
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6
|
6
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33
|
22
|
12
|
14
|
10
|
| Ensembl Acc Id: |
ENSCAFT00000021939 ⟹ ENSCAFP00000020374 |
| Type: |
CODING |
| Position: |
| Dog Assembly | Chr | Position (strand) | Source |
|---|
| CanFam3.1 Ensembl | 26 | 28,141,076 - 28,150,598 (+) | Ensembl |
|
| Ensembl Acc Id: |
ENSCAFT00000088536 ⟹ ENSCAFP00000043580 |
| Type: |
CODING |
| Position: |
| Dog Assembly | Chr | Position (strand) | Source |
|---|
| CanFam3.1 Ensembl | 26 | 28,141,076 - 28,149,801 (+) | Ensembl |
|
| Ensembl Acc Id: |
ENSCAFT00845039513 ⟹ ENSCAFP00845030965 |
| Type: |
CODING |
| Position: |
| Dog Assembly | Chr | Position (strand) | Source |
|---|
| ROS_Cfam_1.0 Ensembl | 26 | 29,534,227 - 29,549,822 (+) | Ensembl |
|
| Ensembl Acc Id: |
ENSCAFT00845039547 ⟹ ENSCAFP00845030992 |
| Type: |
CODING |
| Position: |
| Dog Assembly | Chr | Position (strand) | Source |
|---|
| ROS_Cfam_1.0 Ensembl | 26 | 29,536,343 - 29,554,392 (+) | Ensembl |
|
| Ensembl Acc Id: |
ENSCAFT00845039604 ⟹ ENSCAFP00845031026 |
| Type: |
CODING |
| Position: |
| Dog Assembly | Chr | Position (strand) | Source |
|---|
| ROS_Cfam_1.0 Ensembl | 26 | 29,536,343 - 29,554,384 (+) | Ensembl |
|
| RefSeq Acc Id: |
NM_001003278 ⟹ NP_001003278 |
| RefSeq Status: |
PROVISIONAL |
| Type: |
CODING |
| Position: |
| Dog Assembly | Chr | Position (strand) | Source |
|---|
| CanFam3.1 | 26 | 28,141,076 - 28,150,600 (+) | NCBI | | Dog10K_Boxer_Tasha | 26 | 27,207,866 - 27,225,894 (+) | NCBI | | ROS_Cfam_1.0 | 26 | 29,536,347 - 29,554,384 (+) | NCBI | | UMICH_Zoey_3.1 | 26 | 27,619,698 - 27,637,726 (+) | NCBI | | UNSW_CanFamBas_1.0 | 26 | 27,237,300 - 27,255,320 (+) | NCBI | | UU_Cfam_GSD_1.0 | 26 | 28,226,384 - 28,244,417 (+) | NCBI |
|
| Sequence: |
CCGAGCCCGAGCCGCGGCGGAGACAGCGGGAGCCGGCGCGCGAGCCGCAGGTGCCTCGGGGACTATGAAGCCGAGCTGAGCCAAGATGCTGCGAGAGCCCCTGAGGAGGGCCCAGTTTCTGGAGACTC
AGACTTGGCAGTGAAAACGCCCTTGGGGAGCCCCCGTCACAGGCAGGGGCGCTCTTGGCTCCTGTGAAGAAGGGGCTCAGGGGCCTGGGCAGGGCCAGCGGCACTGCAGCTATGGACCGTGAGCTGGC
CCGGCCCGTGTCCTTGCTGACCCTGCCCGTCTGCAGCCATGTCCACCATGGGCTCCTGGGTGTACATCACGGTGGAGCTGGCCATCGCTGTGCTGGCCATCCTGGGCAATGTGCTGGTGTGCTGGGCT
GTGTGGCTGAACAGCAACCTGCAGAACGTCACCAACTACTTCGTGGTGTCACTGGCGGCAGCCGACATTGCCGTGGGAGTCCTCGCGATCCCCTTCGCCATCACCATCAGCACAGGGTTCTGTGCTGC
CTGCCACAACTGCCTCTTCTTTGCCTGCTTTGTCCTGGTCCTCACTCAGAGCTCCATCTTCAGCCTCCTGGCCATCGCCATTGACCGCTACATCGCCATCCGCATCCCACTCCGGTACAATGGCTTGG
TGACTGGCACAAGGGCCAAGGGCATCATTGCGGTCTGCTGGGTGCTGTCGTTTGCCATTGGCTTGACTCCCATGCTGGGCTGGAACAACTGCAGTCAGCCAAAGGAGGGCAGAAACTACTCACAGGGC
TGCGGGGAGGGCCAGGTGGCCTGTCTCTTTGAGGATGTGGTGCCCATGAACTACATGGTGTACTACAACTTCTTTGCTTTTGTCCTGGTGCCGCTGCTGCTCATGCTGGGTGTCTACTTGCGGATCTT
CCTAGCAGCTCGGCGACAGCTGAAGCAGATGGAGAGCCAGCCTCTGCCTGGGGAGCGGGCTCGGTCCACGCTGCAGAAGGAGGTCCACGCTGCCAAGTCACTGGCCATCATTGTGGGGCTCTTCGCCC
TCTGCTGGCTGCCCCTGCATATCATCAACTGCTTTACCTTCTTTTGCCCAGAGTGTAGCCATGCCCCACTCTGGCTCATGTACCTGACCATCGTCCTCTCCCACACCAATTCTGTTGTGAATCCCTTC
ATCTATGCCTACCGCATCCGTGAGTTTCGCCAGACCTTCCGCAAGATCATTCGCAGCCACGTCCTGAGGCGGCGGGAGCCCTTCAAAGCAGGTGGCACCAGTGCCCGCGCCTTGGCAGCTCATGGCAG
TGATGGAGAGCAGATCAGCCTCCGCCTCAATGGCCATCCTCCTGGGGTGTGGGCCAATGGCAGCGCCCCCCATCCTGAGCGGCGGCCCAATGGCTACACCCTGGGGCTGGTGAGTGGAGGGATTGCCC
CTGAGTCCCATGGCGACATGGGCCTCCCAGATGTGGAGCTCCTCAGCCATGAGCTCAAGGGAGCATGCCCAGAGTCCCCTGGCCTTGAAGGTCCCCTGGCCCAGGATGGAGCAGGAGTGTCCTGATGA
TCCACTCAGTTTGCCTCTTCCTACAGGAAGGAAATCTTTCTCTTTGGTGGATAGAACCAGTCACATTGGGAAAAGAATGAATGTGCCTGGAGACCCTTCTCGTGGCCAGTTCCCACTTTGGACTGAGA
GGAGGGAGCCCTGGCTGGAGCAGCATGTGGCCTAGCAGGAAGGGTTTGGAGTCCAAGAAAGTGGACGTTTCACATCAGAAGGCCCAGCATCAGGTCAGGGCCACAGCACAGAGCATCTTGGCTGGGCA
GGGCCTGGTCCCCCACTCTGGAAGCATCTAGAAGTACCATCCTGATGTGGCAGGGCAGGCTAACTGGCCCTGAGGCTGTGGGGGTGGCTCCAACAGGCCCCCTACCACACACAGACAACACCCTCCCC
AGACTTTTCAAGGATTCAGGAGCTGCTATGCCCAGAGGTGGCGTTTTTCATTTCTTTCTTTCTTTTTTCTCTTTTTTTTTTCCAGGAGAAAATGTTAAACGTGAAGAATGCCTTTTTTTTTTTTTTTA
ATTATTTTCCTTCCCTGGTTGCCAGGTCTGTTGTCAGTCCTGCTGCTAACCTAGCTCCAGGAGTCAGCCCAGGGAGTCCCAGACAGCCCTGTCTGGCTACCATGAACTGCCACGCACTTCTTACACCA
TCAGTCCCAGGGCCATCTCTTGGGGTCACAAAGCTGGGCTCAAGGACAGGGAGCTGTAATGGATTTGCTGCCAGACTGTGGGCTCAGGGGAGGAGATCGGGACTGGCTCACCATGCGGTGTGCCTGGG
TAGCTCAGAGCTGCCCGGTCAGAGGCCCTTTCTAACTGCCTTTCCTTCCGAAGGAATGTTTTTTTCTGAGATAAAATAAAAATGAGCCATGTTGTGTTTTAAAAAAAAAAAAAAA
hide sequence
|
| RefSeq Acc Id: |
NP_001003278 ⟸ NM_001003278 |
| - UniProtKB: |
P11617 (UniProtKB/Swiss-Prot), A0A8C0K1Z2 (UniProtKB/TrEMBL) |
| - Sequence: |
MSTMGSWVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHNCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAVC
WVLSFAIGLTPMLGWNNCSQPKEGRNYSQGCGEGQVACLFEDVVPMNYMVYYNFFAFVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFT
FFCPECSHAPLWLMYLTIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRRREPFKAGGTSARALAAHGSDGEQISLRLNGHPPGVWANGSAPHPERRPNGYTLGLVSGGIAPESHGDMGLPDVE
LLSHELKGACPESPGLEGPLAQDGAGVS
hide sequence
|
|
| Ensembl Acc Id: |
ENSCAFP00000043580 ⟸ ENSCAFT00000088536 |
|
| Ensembl Acc Id: |
ENSCAFP00000020374 ⟸ ENSCAFT00000021939 |
|
| Ensembl Acc Id: |
ENSCAFP00845030992 ⟸ ENSCAFT00845039547 |
|
| Ensembl Acc Id: |
ENSCAFP00845030965 ⟸ ENSCAFT00845039513 |
|
| Ensembl Acc Id: |
ENSCAFP00845031026 ⟸ ENSCAFT00845039604 |
|
|
|
