ADORA2A (adenosine A2a receptor) - Rat Genome Database

Name: ADORA2A
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: ADORA2A (adenosine A2a receptor) Canis lupus familiaris

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Symbol:

ADORA2A

Name:

adenosine A2a receptor

RGD ID:

12228090

Description:

ENCODES a protein that exhibits alpha-actinin binding (ortholog); G protein-coupled adenosine receptor activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); apoptotic signaling pathway (ortholog); astrocyte activation (ortholog); PARTICIPATES IN adenosine signaling pathway; hypoxia inducible factor pathway; ASSOCIATED WITH amphetamine abuse (ortholog); anxiety disorder (ortholog); asthma (ortholog); FOUND IN asymmetric synapse (ortholog); axolemma (ortholog); axon (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

adenosine receptor A2a

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ADORA2A (adenosine A2a receptor)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoMCL, Panther
Mus musculus (house mouse):	Adora2a (adenosine A2a receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Adora2a (adenosine A2a receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Adora2a (adenosine A2a receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ADORA2A (adenosine A2a receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Adora2a (adenosine A2a receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ADORA2A (adenosine A2a receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ADORA2A (adenosine A2a receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Adora2a (adenosine A2a receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ADORA2B (adenosine A2b receptor)	HGNC	OrthoDB

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	28,141,076 - 28,150,600 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	28,141,076 - 28,150,598 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	27,207,866 - 27,225,894 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	29,536,347 - 29,554,384 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	29,534,227 - 29,554,392 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	27,619,698 - 27,637,726 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	27,237,300 - 27,255,320 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	28,226,384 - 28,244,417 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amphetamine abuse (ISO)

anxiety disorder (ISO)

asthma (ISO)

bronchiolitis obliterans (ISO)

cardiomyopathy (ISO)

chronic obstructive pulmonary disease (ISO)

depressive disorder (ISO)

drug allergy (ISO)

epilepsy (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Liver Cirrhosis (ISO)

Genetic Predisposition to Disease (ISO)

Hyperkinesis (ISO)

hypertension (ISO)

Hypotension (ISO)

lung disease (ISO)

movement disease (ISO)

myopia (ISO)

panic disorder (ISO)

pneumonia (ISO)

primary pulmonary hypertension (ISO)

pulmonary edema (ISO)

Reperfusion Injury (ISO)

rheumatoid arthritis (ISO)

schizophrenia (ISO)

Sepsis (ISO)

Sleep Initiation and Maintenance Disorders (ISO)

Spinal Cord Injuries (ISO)

substance-induced psychosis (ISO)

Tremor (ISO)

Ventricular Dysfunction (ISO)

Weight Loss (ISO)

withdrawal disorder (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-activating G protein-coupled receptor signaling pathway (IBA,IEA,ISO)

apoptotic signaling pathway (IEA,ISO)

astrocyte activation (ISO)

eating behavior (IEA,ISO)

excitatory postsynaptic potential (ISO)

G protein-coupled adenosine receptor signaling pathway (IBA,IEA,ISO)

G protein-coupled receptor signaling pathway (IEA,ISO)

inhibitory postsynaptic potential (IEA,ISO)

locomotory behavior (IEA,ISO)

membrane depolarization (ISO)

negative regulation of alpha-beta T cell activation (IEA,ISO)

negative regulation of cell population proliferation (ISO)

negative regulation of inflammatory response (IEA,ISO)

negative regulation of neuron apoptotic process (ISO)

negative regulation of protein kinase activity (ISO)

negative regulation of vascular permeability (ISO)

neuron projection morphogenesis (ISO)

phospholipase C-activating G protein-coupled receptor signaling pathway (ISO)

positive regulation of acetylcholine secretion, neurotransmission (ISO)

positive regulation of apoptotic signaling pathway (IEA,ISO)

positive regulation of circadian sleep/wake cycle, sleep (ISO)

positive regulation of ERK1 and ERK2 cascade (ISO)

positive regulation of glutamate secretion (ISO)

positive regulation of long-term synaptic potentiation (ISO)

positive regulation of protein secretion (ISO)

positive regulation of synaptic transmission, GABAergic (IEA,ISO)

positive regulation of synaptic transmission, glutamatergic (ISO)

positive regulation of urine volume (ISO)

prepulse inhibition (ISO)

presynaptic modulation of chemical synaptic transmission (ISO)

regulation of calcium ion transport (ISO)

regulation of DNA-templated transcription (ISO)

regulation of mitochondrial membrane potential (ISO)

regulation of norepinephrine secretion (ISO)

response to alkaloid (ISO)

response to amphetamine (IEA,ISO)

response to caffeine (ISO)

response to purine-containing compound (IEA)

response to xenobiotic stimulus (ISO)

synaptic transmission, cholinergic (ISO)

synaptic transmission, dopaminergic (IEA,ISO)

synaptic transmission, glutamatergic (ISO)

vasodilation (ISO)

Cellular Component

asymmetric synapse (ISO)

axolemma (ISO)

axon (ISO)

dendrite (ISO)

glutamatergic synapse (ISO)

intermediate filament (ISO)

membrane (IEA)

neuronal cell body (ISO)

plasma membrane (IBA,IEA)

postsynapse (IEA)

postsynaptic membrane (ISO)

presynaptic active zone (ISO)

presynaptic membrane (ISO)

synapse (IEA)

Molecular Function

alpha-actinin binding (ISO)

calmodulin binding (IEA)

enzyme binding (IEA)

G protein-coupled adenosine receptor activity (IBA,IEA,ISO)

G protein-coupled receptor activity (IEA)

identical protein binding (IEA)

lipid binding (IEA)

protein binding (ISO)

protein-containing complex binding (ISO)

type 5 metabotropic glutamate receptor binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

adenosine signaling pathway (ISO)

hypoxia inducible factor pathway (ISO)

References

Additional References at PubMed

PMID:2125216	PMID:2159628	PMID:2541503	PMID:15784967	PMID:16390330	PMID:19833310	PMID:21044214	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ADORA2A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	28,141,076 - 28,150,600 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	28,141,076 - 28,150,598 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	27,207,866 - 27,225,894 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	29,536,347 - 29,554,384 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	29,534,227 - 29,554,392 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	27,619,698 - 27,637,726 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	27,237,300 - 27,255,320 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	28,226,384 - 28,244,417 (+)	NCBI		UU_Cfam_GSD_1.0

ADORA2A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	24,423,597 - 24,442,357 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	24,417,879 - 24,442,357 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	24,819,565 - 24,838,325 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	23,153,530 - 23,168,325 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	22	23,153,645 - 23,162,878	NCBI
Celera	22	8,623,253 - 8,638,061 (+)	NCBI		Celera
Cytogenetic Map	22	q11.23	NCBI
HuRef	22	7,769,458 - 7,788,241 (+)	NCBI		HuRef
CHM1_1	22	24,778,238 - 24,796,999 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	24,885,210 - 24,903,991 (+)	NCBI		T2T-CHM13v2.0

Adora2a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	75,152,711 - 75,170,626 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	75,152,711 - 75,170,618 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	75,316,877 - 75,334,792 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	75,316,877 - 75,334,784 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	74,779,688 - 74,797,533 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	74,769,745 - 74,777,652 (+)	NCBI		MGSCv36	mm8
Celera	10	76,364,032 - 76,382,114 (+)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	38.52	NCBI

Adora2a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	13,315,270 - 13,332,802 (-)	NCBI		GRCr8
mRatBN7.2	20	13,315,848 - 13,333,386 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	13,315,853 - 13,333,386 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	14,022,398 - 14,039,933 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	13,383,344 - 13,400,756 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	13,855,867 - 13,873,399 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	14,265,251 - 14,282,873 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	14,265,252 - 14,282,873 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	16,449,385 - 16,466,147 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	13,815,719 - 13,834,131 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	13,815,944 - 13,825,845 (-)	NCBI
Celera	20	14,801,379 - 14,818,841 (-)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

Adora2a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	7,895,974 - 7,906,505 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955455	7,886,720 - 7,906,214 (+)	NCBI	ChiLan1.0	ChiLan1.0

ADORA2A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	34,212,582 - 34,231,247 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	36,943,248 - 36,961,861 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	5,233,876 - 5,248,622 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	22,099,404 - 22,114,189 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	22,104,253 - 22,114,189 (+)	Ensembl	panpan1.1		panPan2

Adora2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	142,136,447 - 142,156,176 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936619	608,441 - 616,779 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936619	597,970 - 618,564 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADORA2A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	49,468,877 - 49,485,850 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	49,467,186 - 49,485,845 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	52,914,635 - 52,931,654 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ADORA2A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	7,691,678 - 7,706,781 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	7,691,536 - 7,706,926 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666085	4,894,557 - 4,913,637 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adora2a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	9,851,153 - 9,860,094 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624747	9,846,254 - 9,860,938 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in ADORA2A
94 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001003278	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000285	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X14052	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000021939 ⟹ ENSCAFP00000020374

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	26	28,141,076 - 28,150,598 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000088536 ⟹ ENSCAFP00000043580

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	26	28,141,076 - 28,149,801 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845039513 ⟹ ENSCAFP00845030965

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	26	29,534,227 - 29,549,822 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845039547 ⟹ ENSCAFP00845030992

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	26	29,536,343 - 29,554,392 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845039604 ⟹ ENSCAFP00845031026

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	26	29,536,343 - 29,554,384 (+)	Ensembl

RefSeq Acc Id:

NM_001003278 ⟹ NP_001003278

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	26	28,141,076 - 28,150,600 (+)	NCBI
Dog10K_Boxer_Tasha	26	27,207,866 - 27,225,894 (+)	NCBI
ROS_Cfam_1.0	26	29,536,347 - 29,554,384 (+)	NCBI
UMICH_Zoey_3.1	26	27,619,698 - 27,637,726 (+)	NCBI
UNSW_CanFamBas_1.0	26	27,237,300 - 27,255,320 (+)	NCBI
UU_Cfam_GSD_1.0	26	28,226,384 - 28,244,417 (+)	NCBI

Sequence:

show sequence

CCGAGCCCGAGCCGCGGCGGAGACAGCGGGAGCCGGCGCGCGAGCCGCAGGTGCCTCGGGGACT
ATGAAGCCGAGCTGAGCCAAGATGCTGCGAGAGCCCCTGAGGAGGGCCCAGTTTCTGGAGACTC
AGACTTGGCAGTGAAAACGCCCTTGGGGAGCCCCCGTCACAGGCAGGGGCGCTCTTGGCTCCTG
TGAAGAAGGGGCTCAGGGGCCTGGGCAGGGCCAGCGGCACTGCAGCTATGGACCGTGAGCTGGC
CCGGCCCGTGTCCTTGCTGACCCTGCCCGTCTGCAGCCATGTCCACCATGGGCTCCTGGGTGTA
CATCACGGTGGAGCTGGCCATCGCTGTGCTGGCCATCCTGGGCAATGTGCTGGTGTGCTGGGCT
GTGTGGCTGAACAGCAACCTGCAGAACGTCACCAACTACTTCGTGGTGTCACTGGCGGCAGCCG
ACATTGCCGTGGGAGTCCTCGCGATCCCCTTCGCCATCACCATCAGCACAGGGTTCTGTGCTGC
CTGCCACAACTGCCTCTTCTTTGCCTGCTTTGTCCTGGTCCTCACTCAGAGCTCCATCTTCAGC
CTCCTGGCCATCGCCATTGACCGCTACATCGCCATCCGCATCCCACTCCGGTACAATGGCTTGG
TGACTGGCACAAGGGCCAAGGGCATCATTGCGGTCTGCTGGGTGCTGTCGTTTGCCATTGGCTT
GACTCCCATGCTGGGCTGGAACAACTGCAGTCAGCCAAAGGAGGGCAGAAACTACTCACAGGGC
TGCGGGGAGGGCCAGGTGGCCTGTCTCTTTGAGGATGTGGTGCCCATGAACTACATGGTGTACT
ACAACTTCTTTGCTTTTGTCCTGGTGCCGCTGCTGCTCATGCTGGGTGTCTACTTGCGGATCTT
CCTAGCAGCTCGGCGACAGCTGAAGCAGATGGAGAGCCAGCCTCTGCCTGGGGAGCGGGCTCGG
TCCACGCTGCAGAAGGAGGTCCACGCTGCCAAGTCACTGGCCATCATTGTGGGGCTCTTCGCCC
TCTGCTGGCTGCCCCTGCATATCATCAACTGCTTTACCTTCTTTTGCCCAGAGTGTAGCCATGC
CCCACTCTGGCTCATGTACCTGACCATCGTCCTCTCCCACACCAATTCTGTTGTGAATCCCTTC
ATCTATGCCTACCGCATCCGTGAGTTTCGCCAGACCTTCCGCAAGATCATTCGCAGCCACGTCC
TGAGGCGGCGGGAGCCCTTCAAAGCAGGTGGCACCAGTGCCCGCGCCTTGGCAGCTCATGGCAG
TGATGGAGAGCAGATCAGCCTCCGCCTCAATGGCCATCCTCCTGGGGTGTGGGCCAATGGCAGC
GCCCCCCATCCTGAGCGGCGGCCCAATGGCTACACCCTGGGGCTGGTGAGTGGAGGGATTGCCC
CTGAGTCCCATGGCGACATGGGCCTCCCAGATGTGGAGCTCCTCAGCCATGAGCTCAAGGGAGC
ATGCCCAGAGTCCCCTGGCCTTGAAGGTCCCCTGGCCCAGGATGGAGCAGGAGTGTCCTGATGA
TCCACTCAGTTTGCCTCTTCCTACAGGAAGGAAATCTTTCTCTTTGGTGGATAGAACCAGTCAC
ATTGGGAAAAGAATGAATGTGCCTGGAGACCCTTCTCGTGGCCAGTTCCCACTTTGGACTGAGA
GGAGGGAGCCCTGGCTGGAGCAGCATGTGGCCTAGCAGGAAGGGTTTGGAGTCCAAGAAAGTGG
ACGTTTCACATCAGAAGGCCCAGCATCAGGTCAGGGCCACAGCACAGAGCATCTTGGCTGGGCA
GGGCCTGGTCCCCCACTCTGGAAGCATCTAGAAGTACCATCCTGATGTGGCAGGGCAGGCTAAC
TGGCCCTGAGGCTGTGGGGGTGGCTCCAACAGGCCCCCTACCACACACAGACAACACCCTCCCC
AGACTTTTCAAGGATTCAGGAGCTGCTATGCCCAGAGGTGGCGTTTTTCATTTCTTTCTTTCTT
TTTTCTCTTTTTTTTTTCCAGGAGAAAATGTTAAACGTGAAGAATGCCTTTTTTTTTTTTTTTA
ATTATTTTCCTTCCCTGGTTGCCAGGTCTGTTGTCAGTCCTGCTGCTAACCTAGCTCCAGGAGT
CAGCCCAGGGAGTCCCAGACAGCCCTGTCTGGCTACCATGAACTGCCACGCACTTCTTACACCA
TCAGTCCCAGGGCCATCTCTTGGGGTCACAAAGCTGGGCTCAAGGACAGGGAGCTGTAATGGAT
TTGCTGCCAGACTGTGGGCTCAGGGGAGGAGATCGGGACTGGCTCACCATGCGGTGTGCCTGGG
TAGCTCAGAGCTGCCCGGTCAGAGGCCCTTTCTAACTGCCTTTCCTTCCGAAGGAATGTTTTTT
TCTGAGATAAAATAAAAATGAGCCATGTTGTGTTTTAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001003278	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAA32210	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000020374.2
	ENSCAFP00000043580.1
	ENSCAFP00000072809.1
	ENSCAFP00030035115.1
	ENSCAFP00040029336.1
	ENSCAFP00805039575
	ENSCAFP00845030965.1
	ENSCAFP00845030992.1
	ENSCAFP00845031026
	ENSCAFP00845031026.1
GenBank Protein	P11617	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001003278 ⟸ NM_001003278

- UniProtKB:

P11617 (UniProtKB/Swiss-Prot), A0A8C0K1Z2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSTMGSWVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAI
TISTGFCAACHNCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAVC
WVLSFAIGLTPMLGWNNCSQPKEGRNYSQGCGEGQVACLFEDVVPMNYMVYYNFFAFVLVPLLL
MLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFT
FFCPECSHAPLWLMYLTIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRRREPFKAGGTS
ARALAAHGSDGEQISLRLNGHPPGVWANGSAPHPERRPNGYTLGLVSGGIAPESHGDMGLPDVE
LLSHELKGACPESPGLEGPLAQDGAGVS

hide sequence

Ensembl Acc Id:

ENSCAFP00000043580 ⟸ ENSCAFT00000088536

Ensembl Acc Id:

ENSCAFP00000020374 ⟸ ENSCAFT00000021939

Ensembl Acc Id:

ENSCAFP00845030992 ⟸ ENSCAFT00845039547

Ensembl Acc Id:

ENSCAFP00845030965 ⟸ ENSCAFT00845039513

Ensembl Acc Id:

ENSCAFP00845031026 ⟸ ENSCAFT00845039604

Protein Domains

G-protein coupled receptors family 1 profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000013828	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSCAFG00030021927	UniProtKB/Swiss-Prot
	ENSCAFG00040018245	UniProtKB/Swiss-Prot
	ENSCAFG00805027864	UniProtKB/Swiss-Prot
	ENSCAFG00845022393	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000021939.4	UniProtKB/Swiss-Prot
	ENSCAFT00000088536.2	UniProtKB/TrEMBL
	ENSCAFT00000103826.1	UniProtKB/TrEMBL
	ENSCAFT00030040239.1	UniProtKB/Swiss-Prot
	ENSCAFT00040033703.1	UniProtKB/Swiss-Prot
	ENSCAFT00805050512	UniProtKB/Swiss-Prot
	ENSCAFT00845039513.1	UniProtKB/TrEMBL
	ENSCAFT00845039547.1	UniProtKB/TrEMBL
	ENSCAFT00845039604	ENTREZGENE
	ENSCAFT00845039604.1	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Adeno_A2A_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Adenosn_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	cfa:403960	UniProtKB/Swiss-Prot
NCBI Gene	ADORA2A	ENTREZGENE
PANTHER	ADENOSINE RECEPTOR A2A	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	ADENOSINA2AR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ADENOSINER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCRRHODOPSN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	7TM_GPCR_Srsx	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8C0K1Z2	ENTREZGENE
	A0A8I3PG55_CANLF	UniProtKB/TrEMBL
	A0A8I3PR46_CANLF	UniProtKB/TrEMBL
	A0A8P0PP02_CANLF	UniProtKB/TrEMBL
	A0A8P0SWY8_CANLF	UniProtKB/TrEMBL
	AA2AR_CANLF	UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID	VGNC:37666	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Annotations - SMPDB

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Annotations - SMPDB

Imported Annotations - PID (archival)