TIMP1 (TIMP metallopeptidase inhibitor 1) - Rat Genome Database

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Gene: TIMP1 (TIMP metallopeptidase inhibitor 1) Canis lupus familiaris
Analyze
Symbol: TIMP1
Name: TIMP metallopeptidase inhibitor 1
RGD ID: 12124520
Description: ENCODES a protein that exhibits cytokine activity (ortholog); metalloendopeptidase inhibitor activity (ortholog); protease binding (ortholog); INVOLVED IN cartilage development (ortholog); cellular response to peptide (ortholog); cellular response to UV-A (ortholog); PARTICIPATES IN interleukin-6 signaling pathway; ASSOCIATED WITH adrenoleukodystrophy (ortholog); adult respiratory distress syndrome (ortholog); alcoholic liver cirrhosis (ortholog); FOUND IN basement membrane (ortholog); extracellular space (ortholog); INTERACTS WITH spironolactone
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: metalloproteinase inhibitor 1; TIMP-1; tissue inhibitor of matrix metalloproteinase-1; tissue inhibitor of metalloproteinase 1; tissue inhibitor of metalloproteinases 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X41,201,623 - 41,205,314 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX41,201,638 - 41,205,310 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX15,576,764 - 15,580,333 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X41,335,929 - 41,339,499 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX41,335,826 - 41,339,498 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X41,323,532 - 41,327,103 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X41,311,800 - 41,315,371 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X41,404,449 - 41,408,018 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 45 rows

  
Object Symbol
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Original Reference(s)
TIMP1Dogadrenoleukodystrophy severityISOTIMP1 (Homo sapiens)9068941protein:increased expression:cerebrospinal fluidRGDPMID:23185624 and REF_RGD_ID:13204814
TIMP1Dogatherosclerosis amelioratesISOTimp1 (Mus musculus)9068941 RGDPMID:31757932 and REF_RGD_ID:242905202
TIMP1DogBrain Injuries  ISOTimp1 (Rattus norvegicus)9068941mRNA:increased expression:brain and astrocytesRGDPMID:10719361 and REF_RGD_ID:2290468
TIMP1Dogbreast cancer disease_progressionISOTIMP1 (Homo sapiens)9068941protein:increased expression:serumRGDPMID:18172859 and REF_RGD_ID:2290343
TIMP1Dogbreast cancer disease_progressionISOTIMP1 (Homo sapiens)9068941mRNA and protein:increased expression:breastRGDPMID:17114213 more ...
TIMP1DogCAKUT2 treatmentISOTIMP1 (Homo sapiens)9068941 RGDPMID:27448803 and REF_RGD_ID:13204792
TIMP1Dogcholestasis  ISOTimp1 (Rattus norvegicus)9068941 RGDPMID:8707259 and REF_RGD_ID:2290364
TIMP1Dogchronic obstructive pulmonary disease treatmentISOTimp1 (Rattus norvegicus)9068941 RGDPMID:25842729 and REF_RGD_ID:13207319
TIMP1Dogcongestive heart failure  ISOTimp1 (Rattus norvegicus)9068941protein:increased expression:heart left ventricleRGDPMID:10773234 and REF_RGD_ID:2290467
TIMP1DogCOVID-19  ISOTIMP1 (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
TIMP1Dogcystic fibrosis  ISOTIMP1 (Homo sapiens)9068941protein:increased expression:serumRGDPMID:25545245 and REF_RGD_ID:13204794
TIMP1Dogdegenerative disc disease treatmentISOTimp1 (Rattus norvegicus)9068941associated with Renal InsufficiencyRGDPMID:19063844 and REF_RGD_ID:10043178
TIMP1Dogdiabetes mellitus  ISOTIMP1 (Homo sapiens)9068941protein:decreased expression:glomerulusRGDPMID:19506087 and REF_RGD_ID:2312464
TIMP1DogDown syndrome  ISOTIMP1 (Homo sapiens)9068941 RGDPMID:24519975 and REF_RGD_ID:13204810
TIMP1DogEmphysema treatmentISOTimp1 (Rattus norvegicus)9068941 RGDPMID:22633097 and REF_RGD_ID:13207325
TIMP1Dogendometrial carcinoma disease_progressionISOTIMP1 (Homo sapiens)9068941protein:increased expression:endometriumRGDPMID:12487935 and REF_RGD_ID:2298523
TIMP1DogExperimental Diabetes Mellitus  ISOTIMP1 (Homo sapiens)9068941 RGDPMID:17192464 and REF_RGD_ID:2312467
TIMP1DogExperimental Diabetes Mellitus  ISOTimp1 (Rattus norvegicus)9068941protein:increased expression:kidneyRGDPMID:17569353 and REF_RGD_ID:2290354
TIMP1DogExperimental Liver Cirrhosis  ISOTimp1 (Rattus norvegicus)9068941mRNA:increased expression:liverRGDPMID:8707259 and REF_RGD_ID:2290364
TIMP1Doggastric ulcer  ISOTimp1 (Rattus norvegicus)9068941mRNA:increased expression:stomachRGDPMID:15375341 and REF_RGD_ID:10043177
1 to 20 of 45 rows
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Original Reference(s)
TIMP1Dogautistic disorder  ISOTIMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
TIMP1Dogcongenital disorder of glycosylation type IIm  ISOTIMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 22ClinVarPMID:28492532
TIMP1Dogimmune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome  ISOTIMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Insulin-dependent diabetes mellitus secretory diarrhea syndromeClinVarPMID:11137992 more ...
TIMP1Dogneurodegeneration with brain iron accumulation 5  ISOTIMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Beta-propeller protein-associated neurodegenerationClinVarPMID:28492532
TIMP1Dogsyndromic X-linked intellectual disability Lubs type  ISOTIMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Syndromic X-linked intellectual disability Lubs typeClinVarPMID:25741868
TIMP1DogX-linked epilepsy with variable learning disabilities and behavior disorders  ISOTIMP1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:14985377 more ...
TIMP1DogX-linked severe congenital neutropenia  ISOTIMP1 (Homo sapiens)8554872ClinVar Annotator: match by term: X-linked severe congenital neutropeniaClinVarPMID:10698340 more ...
1 to 20 of 23 rows
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Original Reference(s)
TIMP1Dogadult respiratory distress syndrome  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25070658
TIMP1Dogalcoholic liver cirrhosis  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:23274713
TIMP1DogAnimal Disease Models  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21051829
TIMP1Dogaortic valve insufficiency  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21216836
TIMP1Dogautoimmune disease  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25055964
TIMP1Dogcalcinosis  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21335463
TIMP1Dogcholangitis  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25055964
TIMP1DogExperimental Diabetes Mellitus  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21963884
TIMP1DogExperimental Liver Cirrhosis  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16507762 more ...
TIMP1Dogextrahepatic cholestasis  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:28789951
TIMP1DogFemale Urogenital Diseases  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16002989
TIMP1Dogheart disease  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:23558518
TIMP1Dogheart valve disease  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21335463
TIMP1Doghypertension  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21051829
TIMP1DogIgA glomerulonephritis  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25133636
TIMP1DogInflammation  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:17569694
TIMP1DogNeoplasm Invasiveness  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: therapeuticCTDPMID:1318976
TIMP1Dogoral submucous fibrosis  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16311067
TIMP1Dogpulmonary fibrosis  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21468558
TIMP1Dogtype 2 diabetes mellitus  ISOTIMP1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16023759
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Original Reference(s)
TIMP1Dogspironolactone increases expressionEXP 6480464Spironolactone results in increased expression of TIMP1 proteinCTDPMID:20082611


Biological Process
1 to 20 of 21 rows

  
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Original Reference(s)
TIMP1Dogcartilage development  ISOTimp1 (Rattus norvegicus)9068941 RGDPMID:16208432 and REF_RGD_ID:8694091
TIMP1Dogcellular response to peptide  ISOTimp1 (Rattus norvegicus)9068941 RGDPMID:17555880 and REF_RGD_ID:2290355
TIMP1Dogcellular response to UV-A involved_inIEAUniProtKB:P01033 and ensembl:ENSP00000218388150520179 EnsemblGO_REF:0000107
TIMP1Dogcellular response to UV-A involved_inISSUniProtKB:P01033150520179 UniProtGO_REF:0000024
TIMP1Dogconnective tissue replacement involved in inflammatory response wound healing acts_upstream_of_or_withinIEAUniProtKB:P12032 and ensembl:ENSMUSP00000110999150520179 EnsemblGO_REF:0000107
TIMP1Dognegative regulation of apoptotic process  ISOTimp1 (Rattus norvegicus)9068941 RGDPMID:12081564 and REF_RGD_ID:1580121
TIMP1Dognegative regulation of catalytic activity involved_inISSUniProtKB:P01033150520179 UniProtGO_REF:0000024
TIMP1Dognegative regulation of endopeptidase activity involved_inISSUniProtKB:P01033150520179 UniProtGO_REF:0000024
TIMP1Dognegative regulation of membrane protein ectodomain proteolysis involved_inIBAPANTHER:PTN000931945 more ...150520179 GO_CentralGO_REF:0000033
TIMP1Dognegative regulation of membrane protein ectodomain proteolysis involved_inIEAUniProtKB:P01033 and ensembl:ENSP00000218388150520179 EnsemblGO_REF:0000107
TIMP1Dognegative regulation of metallopeptidase activity involved_inISOTIMP1 (Homo sapiens)9068941 PMID:9573338UniProtPMID:9573338
TIMP1Dognegative regulation of trophoblast cell migration involved_inIEAUniProtKB:P01033 and ensembl:ENSP00000218388150520179 EnsemblGO_REF:0000107
TIMP1Dogpositive regulation of cell population proliferation involved_inISSUniProtKB:P01033150520179 UniProtGO_REF:0000024
TIMP1Dogpositive regulation of cell population proliferation involved_inIEAUniProtKB:P01033 and ensembl:ENSP00000218388150520179 EnsemblGO_REF:0000107
TIMP1Dogregulation of integrin-mediated signaling pathway involved_inISSUniProtKB:P01033150520179 UniProtGO_REF:0000024
TIMP1Dogregulation of integrin-mediated signaling pathway involved_inIEAUniProtKB:P01033 and ensembl:ENSP00000218388150520179 EnsemblGO_REF:0000107
TIMP1Dogresponse to cytokine  ISOTimp1 (Rattus norvegicus)9068941 RGDPMID:10435007 and REF_RGD_ID:2290469
TIMP1Dogresponse to cytokine involved_inIBAPANTHER:PTN002625923 more ...150520179 GO_CentralGO_REF:0000033
TIMP1Dogresponse to hormone involved_inIBAPANTHER:PTN002625923 and Timp1 (Rattus norvegicus)150520179 GO_CentralGO_REF:0000033
TIMP1Dogresponse to peptide hormone  ISOTimp1 (Rattus norvegicus)9068941 RGDPMID:1327205 and REF_RGD_ID:2290366
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Cellular Component
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Original Reference(s)
TIMP1Dogbasement membrane  ISOTimp1 (Rattus norvegicus)9068941 RGDPMID:9579471 and REF_RGD_ID:2290365
TIMP1Dogbasement membrane located_inIEAUniProtKB:P12032 and ensembl:ENSMUSP00000110999150520179 EnsemblGO_REF:0000107
TIMP1Dogextracellular matrix located_inIEAUniProtKB:P12032 and ensembl:ENSMUSP00000110999150520179 EnsemblGO_REF:0000107
TIMP1Dogextracellular matrix is_active_inIBAMGI:98752 more ...150520179 GO_CentralGO_REF:0000033
TIMP1Dogextracellular region located_inIEAUniProtKB-KW:KW-0964150520179 UniProtGO_REF:0000043
TIMP1Dogextracellular region located_inIEAUniProtKB-SubCell:SL-0243150520179 UniProtGO_REF:0000044
TIMP1Dogextracellular space located_inIEAUniProtKB:P01033 and ensembl:ENSP00000218388150520179 EnsemblGO_REF:0000107
TIMP1Dogextracellular space is_active_inIBAPANTHER:PTN000931945 more ...150520179 GO_CentralGO_REF:0000033
TIMP1Dogextracellular space located_inISSUniProtKB:P01033150520179 UniProtGO_REF:0000024
1 to 9 of 9 rows

Molecular Function
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Original Reference(s)
TIMP1Dogcytokine activity enablesIEAUniProtKB:P01033 and ensembl:ENSP00000218388150520179 EnsemblGO_REF:0000107
TIMP1Dogcytokine activity enablesISSUniProtKB:P01033150520179 UniProtGO_REF:0000024
TIMP1Dogenzyme inhibitor activity enablesIEAUniProtKB-KW:KW-0481150520179 UniProtGO_REF:0000043
TIMP1Doggrowth factor activity enablesIEAUniProtKB-KW:KW-0339150520179 UniProtGO_REF:0000043
TIMP1Dogmetal ion binding enablesIEAUniProtKB-KW:KW-0479150520179 UniProtGO_REF:0000043
TIMP1Dogmetalloendopeptidase inhibitor activity enablesIBAFB:FBgn0025879 more ...150520179 GO_CentralGO_REF:0000033
TIMP1Dogmetalloendopeptidase inhibitor activity enablesIEAInterPro:IPR001820150520179 InterProGO_REF:0000002
TIMP1Dogmetalloendopeptidase inhibitor activity enablesISSUniProtKB:P01033150520179 UniProtGO_REF:0000024
TIMP1Dogmetalloendopeptidase inhibitor activity enablesIEAUniProtKB:P01033 and ensembl:ENSP00000218388150520179 EnsemblGO_REF:0000107
TIMP1Dogpeptidase inhibitor activity enablesIEAUniProtKB:P01033 and ensembl:ENSP00000218388150520179 EnsemblGO_REF:0000107
TIMP1Dogpeptidase inhibitor activity enablesIEAUniProtKB-KW:KW-0483 and UniProtKB-KW:KW-0646150520179 UniProtGO_REF:0000043
TIMP1Dogprotease binding  ISOMmp1 (Rattus norvegicus)9068941 RGDPMID:21846328 and REF_RGD_ID:7207284
TIMP1Dogprotein binding enablesISOUniProtKB:P209089068941 PMID:20979576IntActPMID:20979576
TIMP1Dogprotein binding enablesISOUniProtKB:P08962 and UniProtKB:P277019068941 PMID:28030805IntActPMID:28030805
TIMP1Dogprotein binding enablesISOUniProtKB:P089629068941 PMID:16917503IntActPMID:16917503
TIMP1Dogprotein binding enablesISOUniProtKB:P147809068941 PMID:2251898UniProtPMID:2251898
TIMP1Dogprotein binding enablesISOUniProtKB:P981589068941PMID:28659595UniProtPMID:28659595 and REF_RGD_ID:13210547
TIMP1Dogzinc ion binding enablesIEAUniProtKB:P01033 and ensembl:ENSP00000218388150520179 EnsemblGO_REF:0000107
1 to 18 of 18 rows

Imported Annotations - PID (archival)

Object Symbol
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Original Reference(s)
TIMP1Doginterleukin-6 signaling pathway   ISOTIMP1 (Homo sapiens)9068941 PIDPID:200146
PMID:1794505   PMID:9931441   PMID:18039671   PMID:18706834   PMID:18717642   PMID:22301074   PMID:22701711   PMID:30032202   PMID:30720210  



TIMP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X41,201,623 - 41,205,314 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX41,201,638 - 41,205,310 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX15,576,764 - 15,580,333 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X41,335,929 - 41,339,499 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX41,335,826 - 41,339,498 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X41,323,532 - 41,327,103 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X41,311,800 - 41,315,371 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X41,404,449 - 41,408,018 (+)NCBIUU_Cfam_GSD_1.0
TIMP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X47,582,436 - 47,586,789 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX47,582,408 - 47,586,789 (+)EnsemblGRCh38hg38GRCh38
GRCh37X47,441,835 - 47,446,188 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X47,326,634 - 47,331,134 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X47,198,084 - 47,202,441NCBI
CeleraX51,636,947 - 51,641,447 (+)NCBICelera
Cytogenetic MapXp11.3NCBI
HuRefX45,154,211 - 45,158,632 (+)NCBIHuRef
CHM1_1X47,472,792 - 47,477,292 (+)NCBICHM1_1
T2T-CHM13v2.0X46,992,326 - 46,996,679 (+)NCBIT2T-CHM13v2.0
Timp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X20,736,524 - 20,740,972 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX20,736,405 - 20,740,974 (+)EnsemblGRCm39 Ensembl
GRCm38X20,870,166 - 20,874,737 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX20,870,166 - 20,874,735 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X20,447,292 - 20,451,863 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X20,027,998 - 20,031,591 (+)NCBIMGSCv36mm8
CeleraX19,001,307 - 19,005,878 (+)NCBICelera
Cytogenetic MapXA1.3NCBI
cM MapX16.38NCBI
Timp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X3,766,509 - 3,772,578 (-)NCBIGRCr8
mRatBN7.2X1,212,969 - 1,217,714 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX1,212,972 - 1,217,664 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX1,241,133 - 1,245,729 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X4,716,824 - 4,721,420 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X1,037,983 - 1,042,580 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X1,364,771 - 1,369,451 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX1,364,786 - 1,369,384 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X2,179,962 - 2,184,814 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X12,542,496 - 12,547,094 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X12,548,051 - 12,552,650 (-)NCBI
CeleraX1,780,586 - 1,785,184 (-)NCBICelera
Cytogenetic MapXq11NCBI
Timp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955516505,789 - 512,118 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955516507,113 - 511,360 (-)NCBIChiLan1.0ChiLan1.0
TIMP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X49,208,573 - 49,213,215 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X49,212,076 - 49,216,587 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X40,018,190 - 40,022,636 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X47,914,906 - 47,919,419 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX47,914,906 - 47,919,419 (+)Ensemblpanpan1.1panPan2
Timp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X33,505,193 - 33,509,420 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650213,345,832 - 13,350,248 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650213,345,936 - 13,350,170 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TIMP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX42,102,172 - 42,106,296 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X42,103,251 - 42,106,289 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X47,372,604 - 47,375,643 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig CytomapXpNCBI
LOC103231892
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X44,759,412 - 44,763,243 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX44,760,531 - 44,765,571 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366656624,012 - 27,843 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Timp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624978121,803 - 124,912 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624978120,723 - 125,006 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in TIMP1
38 total Variants


Assembly: CanFam3.1

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
X 41205195 41205196 G A snv Border Collie (BC597), Bullmastiff (BU002), German Shepherd/Mixed breed (DS032), Whippet (WH083), Sloughi (SG006), German Shepherd/Mixed breed (DS042), Greyhound (GY432), Sloughi (SG005), German Shepherd/Mixed breed (DS041) View more Information




adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10



Ensembl Acc Id: ENSCAFT00000024055   ⟹   ENSCAFP00000022333
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX41,201,638 - 41,205,310 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000065531   ⟹   ENSCAFP00000050322
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX41,201,638 - 41,204,401 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000070963   ⟹   ENSCAFP00000048895
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX41,201,638 - 41,204,401 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000085889   ⟹   ENSCAFP00000043332
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX41,202,661 - 41,204,401 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000092840   ⟹   ENSCAFP00000062428
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX41,201,638 - 41,204,401 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845054234   ⟹   ENSCAFP00845042606
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX41,335,826 - 41,339,498 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845054250   ⟹   ENSCAFP00845042620
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX41,335,883 - 41,338,051 (+)Ensembl
RefSeq Acc Id: NM_001003182   ⟹   NP_001003182
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X41,201,741 - 41,205,311 (+)NCBI
Dog10K_Boxer_TashaX15,576,764 - 15,580,333 (+)NCBI
ROS_Cfam_1.0X41,335,929 - 41,339,499 (+)NCBI
UMICH_Zoey_3.1X41,323,532 - 41,327,103 (+)NCBI
UNSW_CanFamBas_1.0X41,311,800 - 41,315,371 (+)NCBI
UU_Cfam_GSD_1.0X41,404,449 - 41,408,018 (+)NCBI
Sequence:
Protein RefSeqs NP_001003182 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD10632 (Get FASTA)   NCBI Sequence Viewer  
  AAD10633 (Get FASTA)   NCBI Sequence Viewer  
  AAS48102 (Get FASTA)   NCBI Sequence Viewer  
  BAA32393 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00845042606
GenBank Protein P81546 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001003182   ⟸   NM_001003182
- Peptide Label: precursor
- UniProtKB: Q9TQS5 (UniProtKB/Swiss-Prot),   P81546 (UniProtKB/Swiss-Prot),   A0A8C0T2U6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000048895   ⟸   ENSCAFT00000070963
Ensembl Acc Id: ENSCAFP00000062428   ⟸   ENSCAFT00000092840
Ensembl Acc Id: ENSCAFP00000022333   ⟸   ENSCAFT00000024055
Ensembl Acc Id: ENSCAFP00000050322   ⟸   ENSCAFT00000065531
NTR



1 to 27 of 27 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCAFG00000015155 Ensembl
  ENSCAFG00845030572 Ensembl, ENTREZGENE
Ensembl Transcript ENSCAFT00845054234 ENTREZGENE
Gene3D-CATH 2.40.50.120 UniProtKB/Swiss-Prot
  3.90.370.10 UniProtKB/Swiss-Prot
InterPro Netrin_domain UniProtKB/Swiss-Prot
  TIMP UniProtKB/Swiss-Prot
  TIMP-like_OB-fold UniProtKB/Swiss-Prot
  TIMP_C UniProtKB/Swiss-Prot
KEGG Report cfa:403816 UniProtKB/Swiss-Prot
NCBI Gene TIMP1 ENTREZGENE
PANTHER PTHR11844 UniProtKB/Swiss-Prot
  PTHR11844:SF20 UniProtKB/Swiss-Prot
Pfam TIMP UniProtKB/Swiss-Prot
PROSITE NTR UniProtKB/Swiss-Prot
SMART NTR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50242 UniProtKB/Swiss-Prot
UniProt A0A8C0N3C9_CANLF UniProtKB/TrEMBL
  A0A8C0N8Z9_CANLF UniProtKB/TrEMBL
  A0A8C0T2U6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q4H4_CANLF UniProtKB/TrEMBL
  A0A8I3QNP2_CANLF UniProtKB/TrEMBL
  P81546 ENTREZGENE
  Q9TQS5 ENTREZGENE
  TIMP1_CANLF UniProtKB/Swiss-Prot
UniProt Secondary Q9TQS5 UniProtKB/Swiss-Prot
VGNC ID VGNC:47376 ENTREZGENE
1 to 27 of 27 rows