Symbol:
TIMP1
Name:
TIMP metallopeptidase inhibitor 1
RGD ID:
12124520
Description:
ENCODES a protein that exhibits cytokine activity (ortholog); metalloendopeptidase inhibitor activity (ortholog); protease binding (ortholog); INVOLVED IN cartilage development (ortholog); cellular response to peptide (ortholog); cellular response to UV-A (ortholog); PARTICIPATES IN interleukin-6 signaling pathway; ASSOCIATED WITH adrenoleukodystrophy (ortholog); adult respiratory distress syndrome (ortholog); alcoholic liver cirrhosis (ortholog); FOUND IN basement membrane (ortholog); extracellular space (ortholog); INTERACTS WITH spironolactone
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
metalloproteinase inhibitor 1; TIMP-1; tissue inhibitor of matrix metalloproteinase-1; tissue inhibitor of metalloproteinase 1; tissue inhibitor of metalloproteinases 1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 X 41,201,623 - 41,205,314 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl X 41,201,638 - 41,205,310 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha X 15,576,764 - 15,580,333 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 X 41,335,929 - 41,339,499 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl X 41,335,826 - 41,339,498 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 X 41,323,532 - 41,327,103 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 X 41,311,800 - 41,315,371 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 X 41,404,449 - 41,408,018 (+) NCBI UU_Cfam_GSD_1.0
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - PID (archival)
TIMP1 (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 X 41,201,623 - 41,205,314 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl X 41,201,638 - 41,205,310 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha X 15,576,764 - 15,580,333 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 X 41,335,929 - 41,339,499 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl X 41,335,826 - 41,339,498 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 X 41,323,532 - 41,327,103 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 X 41,311,800 - 41,315,371 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 X 41,404,449 - 41,408,018 (+) NCBI UU_Cfam_GSD_1.0
TIMP1 (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 X 47,582,436 - 47,586,789 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl X 47,582,408 - 47,586,789 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 X 47,441,835 - 47,446,188 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 X 47,326,634 - 47,331,134 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 X 47,198,084 - 47,202,441 NCBI Celera X 51,636,947 - 51,641,447 (+) NCBI Celera Cytogenetic Map X p11.3 NCBI HuRef X 45,154,211 - 45,158,632 (+) NCBI HuRef CHM1_1 X 47,472,792 - 47,477,292 (+) NCBI CHM1_1 T2T-CHM13v2.0 X 46,992,326 - 46,996,679 (+) NCBI T2T-CHM13v2.0
Timp1 (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 X 20,736,524 - 20,740,972 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl X 20,736,405 - 20,740,974 (+) Ensembl GRCm39 Ensembl GRCm38 X 20,870,166 - 20,874,737 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl X 20,870,166 - 20,874,735 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 X 20,447,292 - 20,451,863 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 X 20,027,998 - 20,031,591 (+) NCBI MGSCv36 mm8 Celera X 19,001,307 - 19,005,878 (+) NCBI Celera Cytogenetic Map X A1.3 NCBI cM Map X 16.38 NCBI
Timp1 (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 3,766,509 - 3,772,578 (-) NCBI GRCr8 mRatBN7.2 X 1,212,969 - 1,217,714 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl X 1,212,972 - 1,217,664 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx X 1,241,133 - 1,245,729 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 4,716,824 - 4,721,420 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 1,037,983 - 1,042,580 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 1,364,771 - 1,369,451 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 1,364,786 - 1,369,384 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 X 2,179,962 - 2,184,814 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 X 12,542,496 - 12,547,094 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 X 12,548,051 - 12,552,650 (-) NCBI Celera X 1,780,586 - 1,785,184 (-) NCBI Celera Cytogenetic Map X q11 NCBI
Timp1 (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955516 505,789 - 512,118 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955516 507,113 - 511,360 (-) NCBI ChiLan1.0 ChiLan1.0
TIMP1 (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 X 49,208,573 - 49,213,215 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 X 49,212,076 - 49,216,587 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 X 40,018,190 - 40,022,636 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 X 47,914,906 - 47,919,419 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl X 47,914,906 - 47,919,419 (+) Ensembl panpan1.1 panPan2
Timp1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 X 33,505,193 - 33,509,420 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936502 13,345,832 - 13,350,248 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936502 13,345,936 - 13,350,170 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
TIMP1 (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl X 42,102,172 - 42,106,296 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 X 42,103,251 - 42,106,289 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 X 47,372,604 - 47,375,643 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3 Pig Cytomap X p NCBI
LOC103231892 (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 X 44,759,412 - 44,763,243 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl X 44,760,531 - 44,765,571 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666566 24,012 - 27,843 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Timp1 (Heterocephalus glaber - naked mole-rat)
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Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
6
5
5
23
22
16
6
6
6
6
33
22
12
14
10
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSCAFT00000024055 ⟹ ENSCAFP00000022333
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl X 41,201,638 - 41,205,310 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000065531 ⟹ ENSCAFP00000050322
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl X 41,201,638 - 41,204,401 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000070963 ⟹ ENSCAFP00000048895
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl X 41,201,638 - 41,204,401 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000085889 ⟹ ENSCAFP00000043332
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl X 41,202,661 - 41,204,401 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000092840 ⟹ ENSCAFP00000062428
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl X 41,201,638 - 41,204,401 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00845054234 ⟹ ENSCAFP00845042606
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source ROS_Cfam_1.0 Ensembl X 41,335,826 - 41,339,498 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00845054250 ⟹ ENSCAFP00845042620
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source ROS_Cfam_1.0 Ensembl X 41,335,883 - 41,338,051 (+) Ensembl
RefSeq Acc Id:
NM_001003182 ⟹ NP_001003182
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 X 41,201,741 - 41,205,311 (+) NCBI Dog10K_Boxer_Tasha X 15,576,764 - 15,580,333 (+) NCBI ROS_Cfam_1.0 X 41,335,929 - 41,339,499 (+) NCBI UMICH_Zoey_3.1 X 41,323,532 - 41,327,103 (+) NCBI UNSW_CanFamBas_1.0 X 41,311,800 - 41,315,371 (+) NCBI UU_Cfam_GSD_1.0 X 41,404,449 - 41,408,018 (+) NCBI
Sequence:
CATCGCCGCAGACCCAGCGCCCAGAGAGACTCACCAGAGAACCCACCATGGCACCCTTTGCGCCCCTGGCCTCCTGCATCCTGCTGTTGCTGTGGGTGACCGCCCCCAGCAGGGCCTGTACCTGTGCC CCACCCCACCCGCAGACAGCCTTGTGCAACTCCCAAATCGTCATCAGGGCCAAGTTCGTGGGGACCGCAGAAGTCAACCAGACCGACTTAAACCGGCGTTATGAGATCAAGATGACCAAGATGTTCAA GGGTTTCAGCGCCTTGGGGAATGCCTCGGACATCCGCTTCGTCGACACCCCCGCCCTGGAAAGCGTCTGCGGATACTTGCACAGGTCCCAGAACCGCAGCGAGGAGTTTCTGGTCGCCGGAAACCTGC GGGACGGACACTTGCAGATCAACACCTGCAGTTTCGTGGCCCCGTGGAGCAGCCTGAGTACCGCTCAGCGCCGGGGCTTCACCAAGACCTATGCTGCTGGCTGTGAGGGGTGCACAGTGTTTACCTGT TCATCCATCCCCTGCAAACTGCAGAGTGACACTCACTGCTTGTGGACGGACCACTTCCTCACAGGCTCTGACAAGGGTTTCCAGAGCCGCCACCTGGCCTGCCTGCCAAGAGAGCCAGGGATATGCAC CTGGCAGTCCCTGCGGCCCCGGATGGCCTAAATCCTACTCCCCGTGGAAGCCAAAGCCTGCACAGTGTTCACCCCACTTCCCACTCCCGTCTTTCTTTATCCAAAACAATGAAATAAAGAACTACCAT CCAAAAAAAAAAAAAAAAA
hide sequence
RefSeq Acc Id:
NP_001003182 ⟸ NM_001003182
- Peptide Label:
precursor
- UniProtKB:
Q9TQS5 (UniProtKB/Swiss-Prot), P81546 (UniProtKB/Swiss-Prot), A0A8C0T2U6 (UniProtKB/TrEMBL)
- Sequence:
MAPFAPLASCILLLLWVTAPSRACTCAPPHPQTALCNSQIVIRAKFVGTAEVNQTDLNRRYEIKMTKMFKGFSALGNASDIRFVDTPALESVCGYLHRSQNRSEEFLVAGNLRDGHLQINTCSFVAPW SSLSTAQRRGFTKTYAAGCEGCTVFTCSSIPCKLQSDTHCLWTDHFLTGSDKGFQSRHLACLPREPGICTWQSLRPRMA
hide sequence
Ensembl Acc Id:
ENSCAFP00000048895 ⟸ ENSCAFT00000070963
Ensembl Acc Id:
ENSCAFP00000062428 ⟸ ENSCAFT00000092840
Ensembl Acc Id:
ENSCAFP00000022333 ⟸ ENSCAFT00000024055
Ensembl Acc Id:
ENSCAFP00000050322 ⟸ ENSCAFT00000065531
Ensembl Acc Id:
ENSCAFP00000043332 ⟸ ENSCAFT00000085889
Ensembl Acc Id:
ENSCAFP00845042620 ⟸ ENSCAFT00845054250
Ensembl Acc Id:
ENSCAFP00845042606 ⟸ ENSCAFT00845054234