ACTN4 (actinin alpha 4) - Rat Genome Database

Name: ACTN4
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: ACTN4 (actinin alpha 4) Pan paniscus

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Symbol:

ACTN4

Name:

actinin alpha 4

RGD ID:

12041327

Description:

ENCODES a protein that exhibits protein-containing complex binding (ortholog); structural constituent of cytoskeleton (ortholog); structural constituent of postsynaptic actin cytoskeleton (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); bicellular tight junction assembly (ortholog); gene expression (ortholog); PARTICIPATES IN platelet-derived growth factor signaling pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN cell-cell junction (ortholog); cortical actin cytoskeleton (ortholog); cortical cytoskeleton (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

alpha-actinin-4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ACTN4 (actinin alpha 4)	NCBI	Ortholog
Mus musculus (house mouse):	Actn4 (actinin alpha 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Actn4 (actinin alpha 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Actn4 (actinin alpha 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ACTN4 (actinin alpha 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Actn4 (actinin alpha 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ACTN4 (actinin alpha 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ACTN4 (actinin alpha 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Actn4 (actinin alpha 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	44,939,775 - 45,022,391 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	46,810,115 - 46,892,741 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	35,742,758 - 35,825,321 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	44,313,569 - 44,395,508 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	44,313,569 - 44,395,508 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Animal Mammary Neoplasms (ISO)

carcinoma (ISO)

Chemical and Drug Induced Liver Injury (ISO)

chronic kidney disease (ISO)

Coffin-Siris syndrome 2 (ISO)

Experimental Mammary Neoplasms (ISO)

focal segmental glomerulosclerosis (ISO)

focal segmental glomerulosclerosis 1 (ISO)

genetic disease (ISO)

kidney disease (ISO)

maturity-onset diabetes of the young type 1 (ISO)

nephrotic syndrome (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin filament bundle assembly (ISO)

bicellular tight junction assembly (ISO)

gene expression (ISO)

glomerulus development (ISO)

negative regulation of substrate adhesion-dependent cell spreading (IEA)

peroxisome proliferator activated receptor signaling pathway (IEA)

podocyte cell migration (ISO)

positive regulation of cell migration (IEA)

positive regulation of non-canonical NF-kappaB signal transduction (IEA)

positive regulation of pinocytosis (ISO)

positive regulation of transcription by RNA polymerase II (IEA)

protein localization to bicellular tight junction (ISO)

protein transport (IEA)

regulation of apoptotic process (ISO)

response to hypoxia (ISO)

retinoic acid receptor signaling pathway (IEA)

tumor necrosis factor-mediated signaling pathway (IEA)

vesicle transport along actin filament (IEA)

Cellular Component

actin cytoskeleton (IEA)

anchoring junction (IEA)

cell-cell junction (ISO)

cortical actin cytoskeleton (ISO)

cortical cytoskeleton (ISO)

cytoplasm (IEA)

focal adhesion (ISO)

glutamatergic synapse (ISO)

neuron projection (ISO)

nucleus (IEA)

perinuclear region of cytoplasm (IEA)

postsynaptic actin cytoskeleton (IEA,ISO)

protein-containing complex (IEA,ISO)

pseudopodium (ISO)

ribonucleoprotein complex (IEA)

stress fiber (IEA)

Z disc (ISO)

Molecular Function

actin binding (IEA)

actin filament binding (IEA)

calcium ion binding (IEA)

chromatin DNA binding (IEA)

cytoskeletal protein binding (IEA)

metal ion binding (IEA)

nuclear receptor binding (IEA)

nuclear retinoic acid receptor binding (IEA)

nucleoside binding (IEA)

obsolete nuclear receptor coactivator activity (IEA)

protein binding (ISO)

protein homodimerization activity (IEA)

protein-containing complex binding (ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IEA)

structural constituent of cytoskeleton (ISO)

structural constituent of postsynaptic actin cytoskeleton (ISO)

transcription coactivator activity (IEA)

transmembrane transporter binding (IEA)

ubiquitin protein ligase binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

platelet-derived growth factor signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ACTN4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	44,939,775 - 45,022,391 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	46,810,115 - 46,892,741 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	35,742,758 - 35,825,321 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	44,313,569 - 44,395,508 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	44,313,569 - 44,395,508 (+)	Ensembl	panpan1.1		panPan2

ACTN4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	38,647,649 - 38,731,589 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	38,647,649 - 38,731,589 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	39,138,289 - 39,222,229 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	43,830,167 - 43,913,010 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	43,830,166 - 43,913,010	NCBI
Celera	19	35,940,352 - 36,023,163 (+)	NCBI		Celera
Cytogenetic Map	19	q13.2	NCBI
HuRef	19	35,584,836 - 35,667,954 (+)	NCBI		HuRef
CHM1_1	19	39,139,090 - 39,221,979 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	41,451,629 - 41,535,643 (+)	NCBI		T2T-CHM13v2.0

Actn4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	28,592,673 - 28,661,799 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	28,592,673 - 28,661,765 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	28,893,248 - 28,962,351 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	28,893,248 - 28,962,340 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	29,678,273 - 29,747,299 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	28,602,014 - 28,671,040 (-)	NCBI		MGSCv36	mm8
Celera	7	23,454,694 - 23,523,720 (-)	NCBI		Celera
Cytogenetic Map	7	B1	NCBI
cM Map	7	16.94	NCBI

Actn4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	93,310,294 - 93,379,369 (-)	NCBI		GRCr8
mRatBN7.2	1	84,182,783 - 84,251,867 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	84,182,788 - 84,251,847 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	89,592,702 - 89,661,646 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	98,051,807 - 98,120,960 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	91,348,565 - 91,417,509 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	87,078,012 - 87,147,347 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	87,078,020 - 87,147,333 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	88,258,630 - 88,327,965 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	84,000,723 - 84,073,767 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	84,079,711 - 84,151,876 (-)	NCBI
Celera	1	78,572,890 - 78,641,919 (-)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

Actn4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	770,573 - 842,209 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	770,573 - 841,859 (-)	NCBI	ChiLan1.0	ChiLan1.0

ACTN4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	114,354,993 - 114,427,997 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	114,309,693 - 114,427,991 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	113,759,618 - 113,832,649 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	114,956,867 - 115,029,926 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	114,912,152 - 115,030,195 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	114,530,067 - 114,602,907 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	114,147,609 - 114,220,650 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	115,186,154 - 115,259,191 (-)	NCBI		UU_Cfam_GSD_1.0

Actn4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	13,167,758 - 13,237,529 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936801	1,333,077 - 1,404,054 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936801	1,333,077 - 1,402,885 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACTN4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	47,493,919 - 47,565,998 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	47,493,834 - 47,565,999 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	43,045,503 - 43,126,155 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACTN4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	33,290,639 - 33,373,059 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	33,290,622 - 33,374,693 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	11,240,578 - 11,323,802 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Actn4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	12,042,533 - 12,113,886 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624794	12,042,627 - 12,113,762 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008964667	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008964668	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034945703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034945704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063599570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000058509 ⟹ ENSPPAP00000035620

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	44,313,569 - 44,395,508 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000058571 ⟹ ENSPPAP00000035684

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	44,313,595 - 44,394,862 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000058576 ⟹ ENSPPAP00000035687

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	44,313,595 - 44,394,862 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000058588 ⟹ ENSPPAP00000035699

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	44,313,595 - 44,394,862 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000058591 ⟹ ENSPPAP00000035702

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	44,313,595 - 44,394,862 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000058607 ⟹ ENSPPAP00000035718

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	44,313,595 - 44,394,862 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000058615 ⟹ ENSPPAP00000035726

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	44,362,555 - 44,394,862 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000058652 ⟹ ENSPPAP00000035763

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	44,366,091 - 44,394,862 (+)	Ensembl

RefSeq Acc Id:

XM_008964667 ⟹ XP_008962915

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	44,939,775 - 45,022,391 (+)	NCBI
NHGRI_mPanPan1	19	46,810,160 - 46,892,741 (+)	NCBI
Mhudiblu_PPA_v0	19	35,742,758 - 35,825,315 (+)	NCBI
PanPan1.1	19	44,313,569 - 44,395,508 (+)	NCBI

Sequence:

show sequence

CTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTA
CGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAG
GAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGACCT
TCACGGCGTGGTGCAACTCCCACCTGCGGAAGGCAGGCACACAGATCGAGAACATTGATGAGGA
CTTCCGAGACGGGCTCAAGCTCATGCTGCTCCTGGAGGTCATATCAGGGGAGCGGTTACCTAAG
CCGGAGCGGGGGAAGATGAGAGTGCACAAAATCAACAATGTGAACAAAGCGCTGGACTTTATTG
CCAGCAAAGGTGTCAAGCTGGTCTCCATCGGGGCAGAAGAGATTGTGGACGGCAACGCAAAGAT
GACCCTGGGAATGATCTGGACCATCATCCTTAGGTTCGCCATCCAGGACATCTCCGTGGAAGAG
ACCTCGGCCAAGGAAGGGCTCCTTCTCTGGTGCCAGAGAAAAACAGCCCCGTATAAGAATGTCA
ATGTGCAGAACTTCCACATCAGCTGGAAGGATGGTCTTGCCTTCAATGCCCTGATCCACCGGCA
CAGACCAGAGCTGATTGAGTATGACAAGCTGAGGAAGGACGACCCTGTCACCAACCTGAACAAT
GCCTTCGAAGTGGCTGAGAAATACCTCGACATCCCCAAGATGCTGGATGCAGAGGACATCGTGA
ACACGGCCCGGCCCGACGAGAAGGCCATAATGACCTATGTGTCCAGCTTCTACCATGCCTTTTC
AGGAGCGCAGAAGGCTGAAACTGCCGCCAACCGGATCTGTAAGGTGCTGGCTGTCAACCAAGAG
AACGAGCACCTGATGGAGGACTACGAGAAGCTGGCCAGCGACCTCCTGGAGTGGATCCGGCGCA
CCATCCCCTGGCTGGAGGACCGTGTGCCCCAAAAGACTATCCAGGAGATGCAGCAGAAGCTGGA
GGACTTCCGCGACTACCGGCGTGTGCACAAGCCGCCCAAGGTGCAGGAGAAGTGCCAGCTGGAG
ATCAACTTCAACACGCTGCAGACCAAGCTGCGCCTCAGCAACCGGCCCGCCTTCATGCCCTCCG
AGGGCAAGATGGTCTCGGACATCAACAATGGCTGGCAGCACTTGGAGCAGGCTGAGAAGGGCTA
CGAGGAGTGGCTGCTGAATGAGATCCGCAGGCTGGAGCGGCTCGACCACCTGGCAGAGAAGTTC
CGGCAGAAGGCCTCCATCCACGAGGCCTGGACTGACGGGAAGGAAGCCATGCTGAAGCACCGGG
ACTACGAGACGGCCACACTATCGGACATCAAAGCCCTCATTCGCAAGCACGAGGCCTTCGAGAG
CGACCTGGCTGCGCACCAGGACCGCGTGGAGCAGATCGCCGCCATTGCCCAGGAGCTCAACGAG
CTGGATTACTACGACTCCCACAATGTCAACACCCGGTGCCAGAAGATCTGTGACCAGTGGGACG
CCCTCGGTTCTCTGACACATAGTCGCAGGGAAGCCCTGGAGAAAACAGAGAAGCAGCTGGAGGC
CATCGACCAGCTGCACCTGGAATACGCCAAGCGCGCGGCCCCCTTCAACAACTGGATGGAGAGC
GCCATGGAGGACCTCCAGGACATGTTCATCGTCCATACCATCGAGGAGATTGAGGGCCTGATCT
CAGCCCATGACCAGTTCAAGTCCACCCTGCCGGACGCCGATAGGGAGCGCGAGGCCATCCTGGC
CATCCACAAGGAGGCCCAGAGGATCGCTGAGAGCAACCACATCAAGCTGTCGGGCAGCAACCCC
TACACCACCGTCACCCCGCAGATCATCAACTCCAAGTGGGAGAAGGTGCAGCAGCTGGTGCCAA
AACGGGACCACGCCCTCCTGGAGGAGCAGAGCAAGCAGCAGTCCAACGAGCACCTGCGCCGCCA
GTTCGCCAGCCAGGCCAACGTTGTGGGGCCCTGGATCCAGACCAAGATGGAGGAGATCGGGCGC
ATCTCCATTGAGATGAACGGGACCCTGGAGGACCAGCTGAGCCACCTGAAGCAGTATGAACGCA
GCATCGTGGACTACAAGCCCAACCTGGACCTGCTGGAGCAGCAGCACCAGCTCATCCAGGAGGC
CCTCATCTTCGACAACAAGCACACCAACTATACCATGGAGCACATTCGCGTGGGCTGGGAGCAG
CTGCTCACCACCATTGCCCGCACCATCAACGAGGTGGAGAACCAGATCCTCACCCGCGACGCCA
AGGGTATCAGCCAGGAGCAGATGCAGGAGTTCCGGGCGTCCTTCAACCACTTCGACAAGAAGCA
GACAGGCAGCATGGACTCCGATGACTTCAGGGCTCTGCTTATCTCCACAGGATACAGCCTGGGT
GAGGCCGAGTTCAACCGCATCATGAGCCTGGTCGACCCCAACCATAGCGGCCTTGTGACCTTCC
AAGCCTTCATCGACTTCATGTCGCGGGAGACCACCGACACGGACACGGCCGACCAGGTCATCGC
TTCCTTCAAGGTCCTGGCAGGGGACAAGAACTTCATCACAGCTGAGGAGCTGCGGAGAGAGCTG
CCCCCCGACCAGGCTGAGTACTGCATCGCCCGCATGGCGCCATACCAGGGCCCTGATGCCGTGC
CCGGCGCCCTCGACTACAAGTCCTTCTCCACGGCCTTGTATGGCGAGAGCGACCTGTGAGGCCC
CAGAGAGACCCGACCCAACACCCCCCATGGCCTCCAGGAGGGGCCTGGGCAGCCCCACAGTCCC
GTTCCTCCACTCTGTATCTATGCAAAGCACTCTCTGCAGTCCTCTGGGGTGGGTGGGTGGGCAG
GGAGGGGCTGGGGCAGGCTCTCTCCTCTCTCTCTTTGTGGGTTGGCCAGGAGGTTCCCCCGACC
AGGTTGGGGAGACTTGGGGCCAGCGCTTCTGGTCTGGTAAATATGTATGATGTGTTGTGCTTTT
TTAACCAAGGAGGGGCCAGTGGATTCCCACAGCACAACCGGTCCCTTCCATGCCCTGGGGATGC
CTCACCACACCCAGGTCTCTTCCTTTGCTCCCAGGTCCCTTCAAGGCCTCCCCAATCCAGGCCA
AAGCCCCATGTGCCTTGTCCAGGAACTGCCTGGGCCATGCGAGGGGCCAGCAGAGGGCGCCACC
GCCACCTGACGGCTGGGGACCCACCCAGCCCCCTCTCTGCTCCAGACTCACTTGCCATTGCCAG
GAGATGGCCCCAATAAGCACCCCGCTTTTGCAGCAGAGGAGCTGAGTTGGCAGACCGGGCCCCC
CTGAACCGCACCCCATCCCACCAGCCCCGGCCTTGCTTTGTCTGGCCTCACGTGTCTCAGATTT
T

hide sequence

RefSeq Acc Id:

XM_008964668 ⟹ XP_008962916

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	44,939,830 - 45,022,391 (+)	NCBI
NHGRI_mPanPan1	19	46,810,152 - 46,892,741 (+)	NCBI
Mhudiblu_PPA_v0	19	35,742,758 - 35,825,321 (+)	NCBI
PanPan1.1	19	44,313,569 - 44,395,508 (+)	NCBI

Sequence:

show sequence

CTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTA
CGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAG
GAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGACCT
TCACGGCGTGGTGCAACTCCCACCTGCGGAAGGCAGGCACACAGATCGAGAACATTGATGAGGA
CTTCCGAGACGGGCTCAAGCTCATGCTGCTCCTGGAGGTCATATCAGGGGAGCGGTTACCTAAG
CCGGAGCGGGGGAAGATGAGAGTGCACAAAATCAACAATGTGAACAAAGCGCTGGACTTTATTG
CCAGCAAAGGTGTCAAGCTGGTCTCCATCGGGGCAGAAGAGATTGTGGACGGCAACGCAAAGAT
GACCCTGGGAATGATCTGGACCATCATCCTTAGGTTCGCCATCCAGGACATCTCCGTGGAAGAG
ACCTCGGCCAAGGAAGGGCTCCTTCTCTGGTGCCAGAGAAAAACAGCCCCGTATAAGAATGTCA
ATGTGCAGAACTTCCACATCAGCTGGAAGGATGGTCTTGCCTTCAATGCCCTGATCCACCGGCA
CAGACCAGAGCTGATTGAGTATGACAAGCTGAGGAAGGACGACCCTGTCACCAACCTGAACAAT
GCCTTCGAAGTGGCTGAGAAATACCTCGACATCCCCAAGATGCTGGATGCAGAGGATATTGTGG
GCACTCTGAGGCCAGATGAGAAGGCCATCATGACTTACGTGTCCTGCTTCTACCACGCTTTCTC
GGGGGCTCAGAAGGCTGAAACTGCCGCCAACCGGATCTGTAAGGTGCTGGCTGTCAACCAAGAG
AACGAGCACCTGATGGAGGACTACGAGAAGCTGGCCAGCGACCTCCTGGAGTGGATCCGGCGCA
CCATCCCCTGGCTGGAGGACCGTGTGCCCCAAAAGACTATCCAGGAGATGCAGCAGAAGCTGGA
GGACTTCCGCGACTACCGGCGTGTGCACAAGCCGCCCAAGGTGCAGGAGAAGTGCCAGCTGGAG
ATCAACTTCAACACGCTGCAGACCAAGCTGCGCCTCAGCAACCGGCCCGCCTTCATGCCCTCCG
AGGGCAAGATGGTCTCGGACATCAACAATGGCTGGCAGCACTTGGAGCAGGCTGAGAAGGGCTA
CGAGGAGTGGCTGCTGAATGAGATCCGCAGGCTGGAGCGGCTCGACCACCTGGCAGAGAAGTTC
CGGCAGAAGGCCTCCATCCACGAGGCCTGGACTGACGGGAAGGAAGCCATGCTGAAGCACCGGG
ACTACGAGACGGCCACACTATCGGACATCAAAGCCCTCATTCGCAAGCACGAGGCCTTCGAGAG
CGACCTGGCTGCGCACCAGGACCGCGTGGAGCAGATCGCCGCCATTGCCCAGGAGCTCAACGAG
CTGGATTACTACGACTCCCACAATGTCAACACCCGGTGCCAGAAGATCTGTGACCAGTGGGACG
CCCTCGGTTCTCTGACACATAGTCGCAGGGAAGCCCTGGAGAAAACAGAGAAGCAGCTGGAGGC
CATCGACCAGCTGCACCTGGAATACGCCAAGCGCGCGGCCCCCTTCAACAACTGGATGGAGAGC
GCCATGGAGGACCTCCAGGACATGTTCATCGTCCATACCATCGAGGAGATTGAGGGCCTGATCT
CAGCCCATGACCAGTTCAAGTCCACCCTGCCGGACGCCGATAGGGAGCGCGAGGCCATCCTGGC
CATCCACAAGGAGGCCCAGAGGATCGCTGAGAGCAACCACATCAAGCTGTCGGGCAGCAACCCC
TACACCACCGTCACCCCGCAGATCATCAACTCCAAGTGGGAGAAGGTGCAGCAGCTGGTGCCAA
AACGGGACCACGCCCTCCTGGAGGAGCAGAGCAAGCAGCAGTCCAACGAGCACCTGCGCCGCCA
GTTCGCCAGCCAGGCCAACGTTGTGGGGCCCTGGATCCAGACCAAGATGGAGGAGATCGGGCGC
ATCTCCATTGAGATGAACGGGACCCTGGAGGACCAGCTGAGCCACCTGAAGCAGTATGAACGCA
GCATCGTGGACTACAAGCCCAACCTGGACCTGCTGGAGCAGCAGCACCAGCTCATCCAGGAGGC
CCTCATCTTCGACAACAAGCACACCAACTATACCATGGAGCACATTCGCGTGGGCTGGGAGCAG
CTGCTCACCACCATTGCCCGCACCATCAACGAGGTGGAGAACCAGATCCTCACCCGCGACGCCA
AGGGTATCAGCCAGGAGCAGATGCAGGAGTTCCGGGCGTCCTTCAACCACTTCGACAAGAAGCA
GACAGGCAGCATGGACTCCGATGACTTCAGGGCTCTGCTTATCTCCACAGGATACAGCCTGGGT
GAGGCCGAGTTCAACCGCATCATGAGCCTGGTCGACCCCAACCATAGCGGCCTTGTGACCTTCC
AAGCCTTCATCGACTTCATGTCGCGGGAGACCACCGACACGGACACGGCCGACCAGGTCATCGC
TTCCTTCAAGGTCCTGGCAGGGGACAAGAACTTCATCACAGCTGAGGAGCTGCGGAGAGAGCTG
CCCCCCGACCAGGCTGAGTACTGCATCGCCCGCATGGCGCCATACCAGGGCCCTGATGCCGTGC
CCGGCGCCCTCGACTACAAGTCCTTCTCCACGGCCTTGTATGGCGAGAGCGACCTGTGAGGCCC
CAGAGAGACCCGACCCAACACCCCCCATGGCCTCCAGGAGGGGCCTGGGCAGCCCCACAGTCCC
GTTCCTCCACTCTGTATCTATGCAAAGCACTCTCTGCAGTCCTCTGGGGTGGGTGGGTGGGCAG
GGAGGGGCTGGGGCAGGCTCTCTCCTCTCTCTCTTTGTGGGTTGGCCAGGAGGTTCCCCCGACC
AGGTTGGGGAGACTTGGGGCCAGCGCTTCTGGTCTGGTAAATATGTATGATGTGTTGTGCTTTT
TTAACCAAGGAGGGGCCAGTGGATTCCCACAGCACAACCGGTCCCTTCCATGCCCTGGGGATGC
CTCACCACACCCAGGTCTCTTCCTTTGCTCCCAGGTCCCTTCAAGGCCTCCCCAATCCAGGCCA
AAGCCCCATGTGCCTTGTCCAGGAACTGCCTGGGCCATGCGAGGGGCCAGCAGAGGGCGCCACC
GCCACCTGACGGCTGGGGACCCACCCAGCCCCCTCTCTGCTCCAGACTCACTTGCCATTGCCAG
GAGATGGCCCCAATAAGCACCCCGCTTTTGCAGCAGAGGAGCTGAGTTGGCAGACCGGGCCCCC
CTGAACCGCACCCCATCCCACCAGCCCCGGCCTTGCTTTGTCTGGCCTCACGTGTCTCAGATTT
T

hide sequence

RefSeq Acc Id:

XM_034945703 ⟹ XP_034801594

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	44,939,775 - 45,022,391 (+)	NCBI
NHGRI_mPanPan1	19	46,810,142 - 46,892,741 (+)	NCBI
Mhudiblu_PPA_v0	19	35,742,758 - 35,825,321 (+)	NCBI

RefSeq Acc Id:

XM_034945704 ⟹ XP_034801595

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	44,939,793 - 45,022,391 (+)	NCBI
NHGRI_mPanPan1	19	46,810,115 - 46,892,741 (+)	NCBI
Mhudiblu_PPA_v0	19	35,742,759 - 35,825,315 (+)	NCBI

RefSeq Acc Id:

XM_063599570 ⟹ XP_063455640

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	44,939,775 - 45,022,391 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008962915	(Get FASTA)	NCBI Sequence Viewer
	XP_008962916	(Get FASTA)	NCBI Sequence Viewer
	XP_034801594	(Get FASTA)	NCBI Sequence Viewer
	XP_034801595	(Get FASTA)	NCBI Sequence Viewer
	XP_063455640	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000035620
	ENSPPAP00000035620.1
	ENSPPAP00000035684.1
	ENSPPAP00000035687.1
	ENSPPAP00000035699.1
	ENSPPAP00000035702.1
	ENSPPAP00000035718.1
	ENSPPAP00000035726.1
	ENSPPAP00000035763.1

RefSeq Acc Id:	XP_008962915 ⟸ XM_008964667
- Peptide Label:	isoform X5
- UniProtKB:	A0A2R9CB79 (UniProtKB/TrEMBL), A0A2R9C199 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHL RKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVS IGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISW KDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKA IMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLEDRV PQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDIN NGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKHRDYETATLSD IKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDALGSLTHSR REALEKTEKQLEAIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKST LPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEE QSKQQSNEHLRRQFASQANVVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNL DLLEQQHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQ EFRASFNHFDKKQTGSMDSDDFRALLISTGYSLGEAEFNRIMSLVDPNHSGLVTFQAFIDFMSR ETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAVPGALDYKSF STALYGESDL hide sequence

RefSeq Acc Id:	XP_008962916 ⟸ XM_008964668
- Peptide Label:	isoform X4
- UniProtKB:	A0A2R9C199 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHL RKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVS IGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISW KDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVGTLRPDEKA IMTYVSCFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLEDRV PQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDIN NGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKHRDYETATLSD IKALIRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDALGSLTHSR REALEKTEKQLEAIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKST LPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEE QSKQQSNEHLRRQFASQANVVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNL DLLEQQHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQ EFRASFNHFDKKQTGSMDSDDFRALLISTGYSLGEAEFNRIMSLVDPNHSGLVTFQAFIDFMSR ETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAVPGALDYKSF STALYGESDL hide sequence

RefSeq Acc Id:	XP_034801594 ⟸ XM_034945703
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9C1S1 (UniProtKB/TrEMBL), A0A2R9C199 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034801595 ⟸ XM_034945704
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R9C1B6 (UniProtKB/TrEMBL), A0A2R9C199 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSPPAP00000035620 ⟸ ENSPPAT00000058509

Ensembl Acc Id:

ENSPPAP00000035687 ⟸ ENSPPAT00000058576

Ensembl Acc Id:

ENSPPAP00000035684 ⟸ ENSPPAT00000058571

Ensembl Acc Id:

ENSPPAP00000035699 ⟸ ENSPPAT00000058588

Ensembl Acc Id:

ENSPPAP00000035702 ⟸ ENSPPAT00000058591

Ensembl Acc Id:

ENSPPAP00000035763 ⟸ ENSPPAT00000058652

Ensembl Acc Id:

ENSPPAP00000035718 ⟸ ENSPPAT00000058607

Ensembl Acc Id:

ENSPPAP00000035726 ⟸ ENSPPAT00000058615

RefSeq Acc Id:	XP_063455640 ⟸ XM_063599570
- Peptide Label:	isoform X1

Protein Domains

Calponin-homology (CH) EF-hand

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000040184	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000058509.1	UniProtKB/TrEMBL
	ENSPPAT00000058571.1	UniProtKB/TrEMBL
	ENSPPAT00000058576.1	UniProtKB/TrEMBL
	ENSPPAT00000058588.1	UniProtKB/TrEMBL
	ENSPPAT00000058591.1	UniProtKB/TrEMBL
	ENSPPAT00000058607.1	UniProtKB/TrEMBL
	ENSPPAT00000058615.1	UniProtKB/TrEMBL
	ENSPPAT00000058652.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.418.10	UniProtKB/TrEMBL
	1.20.58.60	UniProtKB/TrEMBL
	EF-hand	UniProtKB/TrEMBL
InterPro	Actinin_actin-bd_CS	UniProtKB/TrEMBL
	CH-domain	UniProtKB/TrEMBL
	CH_dom_sf	UniProtKB/TrEMBL
	EF-hand-dom_pair	UniProtKB/TrEMBL
	EF-hand_Ca_insen	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/TrEMBL
	Spectrin/alpha-actinin	UniProtKB/TrEMBL
	Spectrin_repeat	UniProtKB/TrEMBL
KEGG Report	pps:100981951	UniProtKB/TrEMBL
NCBI Gene	ACTN4	ENTREZGENE
PANTHER	ALPHA-ACTININ-4	UniProtKB/TrEMBL
	SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN	UniProtKB/TrEMBL
Pfam	EF-hand_7	UniProtKB/TrEMBL
	EF-hand_8	UniProtKB/TrEMBL
	EFhand_Ca_insen	UniProtKB/TrEMBL
	PF00307	UniProtKB/TrEMBL
	Spectrin	UniProtKB/TrEMBL
PROSITE	ACTININ_1	UniProtKB/TrEMBL
	ACTININ_2	UniProtKB/TrEMBL
	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
	PS50021	UniProtKB/TrEMBL
SMART	EFh	UniProtKB/TrEMBL
	efhand_Ca_insen	UniProtKB/TrEMBL
	SM00033	UniProtKB/TrEMBL
	SPEC	UniProtKB/TrEMBL
Superfamily-SCOP	Spectrin repeat	UniProtKB/TrEMBL
	SSF47473	UniProtKB/TrEMBL
	SSF47576	UniProtKB/TrEMBL
UniProt	A0A2R9C199	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9C1B6	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9C1C2_PANPA	UniProtKB/TrEMBL
	A0A2R9C1G4_PANPA	UniProtKB/TrEMBL
	A0A2R9C1S1	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9C1T8_PANPA	UniProtKB/TrEMBL
	A0A2R9C4D8_PANPA	UniProtKB/TrEMBL
	A0A2R9CB79	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)