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Gene: Pam (peptidylglycine alpha-amidating monooxygenase) Mus musculus
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Symbol: Pam
Name: peptidylglycine alpha-amidating monooxygenase
Description: Predicted to have several functions, including metal ion binding activity; peptidylamidoglycolate lyase activity; and peptidylglycine monooxygenase activity. Predicted to be involved in several processes, including fatty acid primary amide biosynthetic process; peptide amidation; and protein homooligomerization. Predicted to localize to several cellular components, including the perikaryon; secretory granule membrane; and trans-Golgi network. Is expressed in several structures, including alimentary system; central nervous system; forelimb bud; limb interdigital region; and sensory organ. Orthologous to human PAM (peptidylglycine alpha-amidating monooxygenase); PARTICIPATES IN melanocortin system pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: peptidyl-glycine alpha-amidating monooxygenase; PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PRECURSOR (PAM); PHM
Orthologs:
Homo sapiens (human) : PAM (peptidylglycine alpha-amidating monooxygenase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pam (peptidylglycine alpha-amidating monooxygenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pam (peptidylglycine alpha-amidating monooxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : PAM (peptidylglycine alpha-amidating monooxygenase)
Canis lupus familiaris (dog) : PAM (peptidylglycine alpha-amidating monooxygenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pam (peptidylglycine alpha-amidating monooxygenase)
Sus scrofa (pig) : PAM (peptidylglycine alpha-amidating monooxygenase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl197,795,114 - 98,095,646 (-)Ensembl
GRCm38197,821,091 - 98,095,853 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37199,717,671 - 99,992,209 (-)NCBIGRCm37mm9NCBIm37
MGSCv36199,651,500 - 99,925,919 (-)NCBImm8
Celera1100,701,674 - 100,975,784 (-)NCBICelera
Cytogenetic Map1 DNCBI
cM Map147.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pam
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11056
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.