Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

Term:
[(R)-1-L-prolylpyrrolidin-2-yl]boronic acid (CHEBI:41285)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
(1R)-1-\{[(1-\{N-[(S)-hydroxy(morpholin-4-yl)methyl]-beta-phenyl-D-phenylalanyl\}-1H-pyrrol-2-yl)carbonyl]amino\}-4-methoxybutylboronic acid 
(1R)-3-methyl-1-\{[N-(morpholin-4-ylcarbonyl)-3-(1-naphthyl)-D-alanyl]amino\}butylboronic acid 
(1S)-2-[(2S,5R)-2-(aminomethyl)-5-ethynylpyrrolidin-1-yl]-1-cyclopentyl-2-oxoethanamine 
(1S)-2-[(2S,5R)-2-(aminomethyl)-5-prop-1-yn-1-ylpyrrolidin-1-yl]-1-cyclopentyl-2-oxoethanamine 
(1S,2R,5S)-5-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-2-(2,4,5-trifluorophenyl)cyclohexanamine 
(2S)-2-cyano-1-(4-phenyl-L-phenylalanyl)pyrrolidine 
(2S)-3-(3-pyridyl)propyl 1-(3,3-dimethyl-1,2-dioxopentyl)pyrrolidine-2-carboxylate 
(2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-[4-(\{(3R)-1-[(1Z)-ethanimidoyl]pyrrolidin-3-yl\}oxy)phenyl]propanoic acid 
(2S)-3-methyl-2-((2R,3S)-3-[(methylsulfonyl)amino]-1-\{[2-(pyrrolidin-1-ylmethyl)-1,3-oxazol-4-yl]carbonyl\}pyrrolidin-2-yl)butanoic acid 
(2S,3S)-3-\{3-[4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl\}-1-oxo-1-pyrrolidin-1-ylbutan-2-amine 
(2S,4R)-1-acetyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(benzothiazol-2-ylcarbonyl)butyl]-4-hydroxypyrrolidine-2-carboxamide 
(2S,4S,5R)-1-(4-tert-butylbenzoyl)-2-isobutyl-5-(1,3-thiazol-2-yl)pyrrolidine-2,4-dicarboxylic acid 
(2S,4S,5R)-2-isobutyl-5-(2-thienyl)-1-[4-(trifluoromethyl)benzoyl]pyrrolidine-2,4-dicarboxylic acid 
(3S)-1-[(E)-amino(imino)methyl]-N-(\{(2S)-1-[N-(2-naphthylsulfonyl)-L-seryl]pyrrolidin-2-yl\}methyl)piperidine-3-carboxamide 
(3S)-1-\{[(3,5-dimethylisoxazol-4-yl)amino]carbonyl\}-4,4-dimethylpyrrolidin-3-yl \{(1S)-1-[1-hydroxy-2-oxo-2-\{[(1R)-1-phenylethyl]amino\}ethyl]pentyl\}carbamate 
(3S,4S)-3,4-dihydroxy-L-proline 
(4S)-1-[(4-butoxyphenyl)sulfonyl]-N-hydroxy-4-[(methylsulfonyl)amino]-D-prolinamide 
(4S)-N-hydroxy-4-(methoxyamino)-1-[(4-methoxyphenyl)sulfonyl]-D-prolinamide 
(5S)-5-(carboxymethyl)-L-proline 
(\{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino\}methyl)boronic acid 
(R)-4-hydroxy-1-methyl-L-proline 
1-(3-mercapto-2-methylpropionyl)pyrrolidine-2-carboxylic acid 
1-[(2E,4E)-2,4-decadienoyl]pyrrolidine 
1-[(2E,4E)-2,4-dodecadienoyl]pyrrolidine 
1-[(2E,4E,6E)-2,4,6-dodecatrienoyl]pyrrolidine 
1-[(2R)-2-amino-2-cyclohexylacetyl]-N-\{5-chloro-2-[2-(ethylamino)-2-oxoethoxy]benzyl\}-L-prolinamide 
1-[(3aR)-5-\{[3-(2,4-difluorophenyl)-5,6-dihydroimidazo[1,5-a]pyrazin-7(8H)-yl]carbonyl\}-6-methoxy-3aH-pyrrolo[2,3-b]pyridin-3-yl]-2-[(3R)-3-hydroxypyrrolidin-1-yl]-2-oxoethanone 
1-[3,3-dimethyl-2-(2-2-methylaminopropionylamino)butyryl]-4-phenoxypyrrolidine-2-[N-(1,2,3,4-tetrahydronaphthalen-1-yl)]carboxamide 
1-\{[1-(2-amino-3-phenylpropionyl)pyrrolidine-2-carbonyl]amino\}-2-(3-cyanophenyl)ethaneboronic acid 
1-propanoylproline 
2-(2-amino-1,3-thiazol-4-yl)-2-(1-carboxy-1-methylethoxyimino)acetylaminomethylboronic acid 
2-[4-(\{(S)-1-[((S)-2-\{[(RS)-3,3,3-trifluoro-1-isopropyl-2-oxopropyl]aminocarbonyl\}pyrrolidin-1-yl)carbonyl]-2-methylpropyl\}aminocarbonyl)benzoylamino]acetic acid 
2-[4-(\{2-[(2S,5R)-2-(aminomethyl)-5-ethynylpyrrolidin-1-yl]-2-oxoethyl\}amino)-4-methylpiperidin-1-yl]isonicotinic acid 
2-amino-3-methyl-1-pyrrolidin-1-ylbutan-1-one 
3'-L-prolyl-AMP 
3-acetylphenylboronic acid 
3-hydroxy-L-proline +  
4-\{[(2R,5S)-5-\{[(2S)-2-(aminomethyl)pyrrolidin-1-yl]carbonyl\}pyrrolidin-2-yl]methoxy\}-3-tert-butylbenzoic acid 
4-\{[(E)-amino(imino)methyl]amino\}-N-(\{(2S)-1-[N-(2-naphthylsulfonyl)-L-seryl]pyrrolidin-2-yl\}methyl)butanamide 
4-hydroxy-L-proline +  
4-O-(beta-L-Araf)-cis-L-Hyp 
4-O-(beta-L-Araf-(1->2)-beta-L-Araf-(1->2)-beta-L-Araf)-cis-L-Hyp 
4-oxo-L-proline 
5-oxo-L-proline +   
5-oxo-L-proline 2-naphthylamide 
6-(4-\{(1S,2S)-2-amino-1-[(dimethylamino)carbonyl]-3-[(3S)-3-fluoropyrrolidin-1-yl]-3-oxopropyl\}phenyl)-1H-[1,2,4]triazolo[1,5-a]pyridin-4-ium 
[(R)-1-L-prolylpyrrolidin-2-yl]boronic acid 
An N-acylpyrrolidine obtained by formal condenstion of the carboxy group of L-proline and the secondary amino group of (R)-pyrrolidine-2-carboxylic acid.
\{(2S,3S,4S)-2-carboxy-4-[(1Z,3E,5R)-5-carboxy-1-methylhexa-1,3-dienyl]pyrrolidin-3-yl\}acetic acid 
aculene A 
aculene B 
alpha-Allokainic acid 
aniracetam  
beta-phenyl-D-phenylalanyl-N-(2,5-dichlorobenzyl)-L-prolinamide 
boronic acid +   
C-terminal boronic acid peptide +  
captopril +   
celesticetin 
dextromoramide 
domoic acid  
EC 3.4.11.* (aminopeptidase) inhibitor +   
EC 3.4.13.* (dipeptidase) inhibitor +   
EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor +   
EC 3.4.15.* (peptidyl-dipeptidase) inhibitor +   
EC 3.4.17* (metallocarboxypeptidase) inhibitor +  
EC 3.4.19.* (omega-peptidase) inhibitor +   
EC 3.4.21.* (serine endopeptidase) inhibitor +   
EC 3.4.22.* (cysteine endopeptidase) inhibitor +   
EC 3.4.23.* (aspartic endopeptidase) inhibitor +   
EC 3.4.24.* (metalloendopeptidase) inhibitor +   
elbasvir +  
fosinopril  
fosinoprilat +   
ixazomib +   
kainic acid +   
L-hydroxyproline 2-naphthylamide 
L-prolinamide 
L-proline 2-naphthylamide 
ledipasvir +   
lincomycin +   
LSM-1512 
malyngamide B 
matrix metalloproteinase inhibitor +   
methyl 1-methyl-5-oxo-L-prolinate 
methyl 4-\{[(\{[(2R,5S)-5-\{[(2S)-2-(aminomethyl)pyrrolidin-1-yl]carbonyl\}pyrrolidin-2-yl]methyl\}amino)carbonyl]amino\}benzoate 
N(2)-[(benzyloxy)carbonyl]-N(1)-((3R)-1-\{N-[(benzyloxy)carbonyl]-L-leucyl\}-4-oxopyrrolidin-3-yl)-L-leucinamide 
N-(2,4-dinitrophenyl)-L-proline 
N-(\{(2S)-1-[(3R)-3-amino-4-(2-fluorophenyl)butanoyl]pyrrolidin-2-yl\}methyl)benzamide 
N-(trans-4-\{(1S,2S)-2-amino-3-[(3S)-3-fluoropyrrolidin-1-yl]-1-methyl-3-oxopropyl\}cyclohexyl)-N-methylacetamide 
N-[(2R,3S)-1-((2S)-2-\{[(cyclopentylamino)carbonyl]amino\}-3-methylbutanoyl)-2-(1-formylcyclobutan-1-yl)pyrrolidin-3-yl]cyclopropanecarboxamide 
N-[4-(D-prolinosulfonyl)benzoyl]-L-glutamic acid 
N-[4-(morpholin-4-ylcarbonyl)benzoyl]-L-valyl-N-[(3S)-5,5,6,6,6-pentafluoro-2-methyl-4-oxohexan-3-yl]-L-prolinamide 
N-\{(2S,3R)-2-[(1S)-1-formyl-2-methylpropyl]-1-[(2E)-4-piperidin-1-ylbut-2-enoyl]pyrrolidin-3-yl\}methanesulfonamide 
N-acetyl-D-proline 
N-acetyl-L-proline +  
N-acetyltryptophyl-N(1)-\{3-[1-(N-acetyltryptophylvalyl)pyrrolidin-2-yl]-1-benzyl-2,3-dihydroxypropyl\}valinamide 
N-benzyloxycarbonyl-L-prolyl-L-prolinal 
N-ethoxycarbonyl-D-phenylalanylprolyl-2-(4-aminobutyl)hydrazine 
N-methylproline 
N-Nitrosohydroxyproline 
N-Nitrosoproline 
PF-956980  
PHA-665752  
phenylboronic acid +  
protease inhibitor +   
tert-butyl \{1-[2-(1-formylpropyl)-3-methanesulfonylaminopyrrolidine-1-carbonyl]-2-methylpropyl\}carbamate 
Variotin 
velpatasvir +  
zofenopril 
zofenoprilat 

Synonyms
Exact Synonyms: [(2R)-1-L-prolylpyrrolidin-2-yl]boronic acid
Related Synonyms: Formula=C9H17BN2O3 ;   InChI=1S/C9H17BN2O3/c13-9(7-3-1-5-11-7)12-6-2-4-8(12)10(14)15/h7-8,11,14-15H,1-6H2/t7-,8-/m0/s1 ;   InChIKey=XSBZZZGVAIXJLD-YUMQZZPRSA-N ;   Pro-boroPro ;   SMILES=OB(O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1
Xrefs: PDBeChem:BPR ;   PMID:10098663 ;   PMID:1353423 ;   PMID:16330047 ;   PMID:1671716 ;   PMID:16802131 ;   PMID:7780144 ;   PMID:7892748 ;   PMID:7910536 ;   PMID:7918465 ;   PMID:8103356 ;   Reaxys:14528096

paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.