Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:dicoumarol pharmacodynamics pathway
go back to main search page
Accession:PW:0002497 term browser browse the term
Definition:The pathway of dicoumarol-target interaction and of the biochemical or physiological responses to drug. Dicoumarol is a naturally occurring anticoagulant that antagonizes the vitamin K dependent clotting pathway. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00270;   SMP:00656;   dicumarol pharmacodynamics pathway


show annotations for term's descendants           Sort by:
dicoumarol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain EXP SMPDB SMP:00270 SMP:00656 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G F10 coagulation factor X EXP SMPDB SMP:00270 SMP:00656 NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529 		JBrowse link
G F11 coagulation factor XI EXP SMPDB SMP:00270 SMP:00656 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681 		JBrowse link
G F12 coagulation factor XII EXP SMPDB SMP:00270 SMP:00656 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583 		JBrowse link
G F13A1 coagulation factor XIII A chain EXP SMPDB SMP:00270 SMP:00656 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013 		JBrowse link
G F13B coagulation factor XIII B chain EXP SMPDB SMP:00270 SMP:00656 NCBI chr 1:197,038,741...197,067,260
Ensembl chr 1:197,038,741...197,067,260 		JBrowse link
G F2 coagulation factor II, thrombin EXP SMPDB SMP:00270 SMP:00656 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G F3 coagulation factor III, tissue factor EXP SMPDB SMP:00270 SMP:00656 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G F5 coagulation factor V EXP SMPDB SMP:00270 SMP:00656 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588 		JBrowse link
G F7 coagulation factor VII EXP SMPDB SMP:00270 SMP:00656 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685 		JBrowse link
G F8 coagulation factor VIII EXP SMPDB SMP:00270 SMP:00656 NCBI chr  X:154,835,792...155,022,723
Ensembl chr  X:154,835,788...155,026,940 		JBrowse link
G F9 coagulation factor IX EXP SMPDB SMP:00270 SMP:00656 NCBI chr  X:139,530,739...139,563,459
Ensembl chr  X:139,530,739...139,563,459 		JBrowse link
G FGA fibrinogen alpha chain EXP SMPDB SMP:00270 SMP:00656 NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742 		JBrowse link
G FGB fibrinogen beta chain EXP SMPDB SMP:00270 SMP:00656 NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807 		JBrowse link
G FGG fibrinogen gamma chain EXP SMPDB SMP:00270 SMP:00656 NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967 		JBrowse link
G GGCX gamma-glutamyl carboxylase EXP SMPDB SMP:00270 SMP:00656 NCBI chr 2:85,544,720...85,561,493
Ensembl chr 2:85,544,720...85,561,532 		JBrowse link
G KLKB1 kallikrein B1 EXP SMPDB SMP:00270 SMP:00656 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471 		JBrowse link
G PLAT plasminogen activator, tissue type EXP SMPDB SMP:00270 SMP:00656 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLG plasminogen EXP SMPDB SMP:00270 SMP:00656 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097 		JBrowse link
G VKORC1 vitamin K epoxide reductase complex subunit 1 EXP SMPDB SMP:00270 SMP:00656 NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5957
    drug pathway 412
      blood and blood forming organs drug pathway 67
        antithrombotic drug pathway 67
          anticoagulant drug pathway 32
            vitamin K antagonist drug pathway 31
              dicoumarol drug pathway 20
                dicoumarol pharmacodynamics pathway 20
paths to the root