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Gene: GGCX (gamma-glutamyl carboxylase) Homo sapiens
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Symbol: GGCX
Name: gamma-glutamyl carboxylase
Description: Predicted to have gamma-glutamyl carboxylase activity. Predicted to be involved in blood coagulation and peptidyl-glutamic acid carboxylation. Predicted to localize to the endoplasmic reticulum membrane. Implicated in coagulation protein disease and inherited blood coagulation disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ26629; peptidyl-glutamate 4-carboxylase; vitamin K gamma glutamyl carboxylase; vitamin K-dependent gamma-carboxylase; VKCFD1
Orthologs:
Mus musculus (house mouse) : Ggcx (gamma-glutamyl carboxylase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ggcx (gamma-glutamyl carboxylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ggcx (gamma-glutamyl carboxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : GGCX (gamma-glutamyl carboxylase)
Canis lupus familiaris (dog) : GGCX (gamma-glutamyl carboxylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ggcx (gamma-glutamyl carboxylase)
Sus scrofa (pig) : GGCX (gamma-glutamyl carboxylase)
Chlorocebus sabaeus (green monkey) : GGCX (gamma-glutamyl carboxylase)
Heterocephalus glaber (naked mole-rat) : Ggcx (gamma-glutamyl carboxylase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl285,544,720 - 85,561,547 (-)Ensembl
GRCh38285,544,720 - 85,561,527 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37285,771,978 - 85,788,657 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36285,629,714 - 85,642,090 (-)NCBINCBI36hg18NCBI36
Build 34285,687,861 - 85,700,237NCBI
Celera285,604,381 - 85,616,845 (-)NCBI
Cytogenetic Map2p11.2NCBI
HuRef285,669,320 - 85,686,004 (-)NCBIHuRef
CHM1_1285,701,650 - 85,718,463 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GGCX
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68554
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.