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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal digestive system physiology
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Accession:MP:0001663 term browser browse the term
Definition:any functional anomaly of the organ system that converts ingested food to nutrients and energy
Synonyms:exact_synonym: digestive system physiology abnormalities;   digestive system: functional anomalies
 alt_id: MP:0002142
 xref: MGI:2173602


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abnormal gastrointestinal motility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghsr growth hormone secretagogue receptor IMP compared to wild type rats in response to ghrelin (CHEBI:75431) RGD PMID:21258824 RGD:150520012 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Ghsrm1Mcwi growth hormone secretagogue receptor; mutation 1, Medical College of Wisconsin IMP compared to wild type rats in response to ghrelin (CHEBI:75431) RGD PMID:21258824 RGD:150520012
abnormal intestinal absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IMP RGD PMID:22049154 RGD:8657330 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1aem2Sage ATP binding cassette subfamily B member 1A; ZFN induced mutant 2, Sage IMP RGD PMID:22049154 RGD:8657330
decreased defecation amount term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pmch pro-melanin-concentrating hormone IMP RGD PMID:19934402 RGD:150429945 NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250 		JBrowse link
G Pmchm1Hubr pro-melanin-concentrating hormone; ENU induced mutant1, Hubr IMP RGD PMID:19934402 RGD:150429945
increased defecation amount term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gad1 glutamate decarboxylase 1 IMP RGD PMID:33293518 RGD:158012686 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad1em15Yyan glutamate decarboxylase 1; CRISPR/Cas9 induced mutant 15, Yyan IMP RGD PMID:33293518 RGD:158012686
G Mc4r melanocortin 4 receptor IMP RGD PMID:21527895 RGD:6478803 NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719 		JBrowse link
G Mc4rm1Hubr melanocortin 4 receptor; ENU induced mutation 1, Hubr IMP RGD PMID:21527895 RGD:6478803
increased stomach pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 IAGP DNA:deletion:exon (rat) RGD PMID:16368876 RGD:1581602 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
G Kcnq1dfk potassium voltage-gated channel subfamily Q member 1;deafness Kyoto IAGP RGD PMID:16368876 RGD:1581602
intestinal hypoperistalsis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:7542218 RGD:12910748 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
rectal hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway sexual_dimorphism IMP compared to females RGD PMID:17360473 RGD:1601201 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G ApcPirc APC, WNT signaling pathway regulator; polyposis in the rat colon sexual_dimorphism IMP compared to females RGD PMID:17360473 RGD:1601201
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5420
    digestive/alimentary phenotype 81
      abnormal digestive system physiology 31
        abnormal defecation + 10
        abnormal digestion + 5
        abnormal exocrine pancreas physiology + 0
        abnormal gastroesophageal sphincter physiology + 0
        abnormal gastrointestinal motility + 6
        abnormal gut flora balance 0
        abnormal intestine physiology + 4
        abnormal salivary gland physiology + 0
        abnormal stomach pH + 3
        aerophagia 0
        dysphagia 0
        esophageal inflammation 0
        gastrointestinal hemorrhage + 3
        meteorism 0
        palate inflammation 0
        peritoneal inflammation 0
        stomach inflammation 0
        stomatitis 0
paths to the root