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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:neuropeptide signaling pathway
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Accession:GO:0007218 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
Synonyms:exact_synonym: neuropeptide signalling pathway
 never_in_taxon: NCBITaxon:4751 ! Fungi


show annotations for term's descendants           Sort by:
neuropeptide signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1 adenylate cyclase activating polypeptide 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:13,414,618...13,421,668
Ensembl chr18:15,713,479...15,717,749 		JBrowse link
G AGRP agouti related neuropeptide acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9311920) RGD
MGI
TreeGrafter
Ensembl		 PMID:9311920 PMID:10875247 GO_REF:0000107 GO_REF:0000118 RGD:632165 NCBI chr16:47,827,532...47,872,727
Ensembl chr16:67,216,008...67,217,258 		JBrowse link
G ASL argininosuccinate lyase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9322931) Ensembl
MGI		 PMID:9322931 GO_REF:0000107 NCBI chr 7:59,908,648...59,948,822
Ensembl chr 7:73,142,842...73,157,472
Ensembl chr 7:73,142,842...73,157,472
Ensembl chr 7:73,142,842...73,157,472 		JBrowse link
G BRS3 bombesin receptor subtype 3 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:125,617,592...125,623,411
Ensembl chr  X:135,883,613...135,888,069 		JBrowse link
G CALCA calcitonin related polypeptide alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7698182) Ensembl
MGI		 PMID:7698182 GO_REF:0000107 NCBI chr11:15,055,897...15,061,539
Ensembl chr11:14,745,588...14,751,267 		JBrowse link
G CARTPT CART prepropeptide involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:43,591,683...43,593,586
Ensembl chr 5:44,236,114...44,238,229 		JBrowse link
G CCKAR cholecystokinin A receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:20,881,340...20,890,986
Ensembl chr 4:26,157,702...26,166,773 		JBrowse link
G CORT cortistatin ISO RGD PMID:11817718 RGD:728223 NCBI chr 1:9,210,186...9,212,201 JBrowse link
G CRCP CGRP receptor component involved_in IEA Ensembl GO_REF:0000107
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:11784785 RGD:70397 NCBI chr17:11,261,435...11,313,630
Ensembl chr17:11,650,057...11,701,208 		JBrowse link
G ECRG4 ECRG4 augurin precursor involved_in ISO (PMID:20233222) UniProt PMID:20233222 NCBI chr2A:95,762,149...95,774,834
Ensembl chr2A:107,140,895...107,152,967 		JBrowse link
G GAL galanin and GMAP prepropeptide involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12533601) UniProt
MGI
TreeGrafter		 PMID:12533601 GO_REF:0000043 GO_REF:0000118 NCBI chr11:63,770,758...63,777,421
Ensembl chr11:67,075,547...67,081,696 		JBrowse link
G GALP galanin like peptide involved_in IEA UniProt GO_REF:0000043 NCBI chr19:53,201,889...53,212,832
Ensembl chr19:61,996,543...62,007,333 		JBrowse link
G GALR1 galanin receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chr18:70,643,718...70,664,068
Ensembl chr18:73,899,995...73,917,752 		JBrowse link
G GALR2 galanin receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:70,019,383...70,028,689
Ensembl chr17:75,578,072...75,580,806 		JBrowse link
G GALR3 galanin receptor 3 ISO RGD PMID:9722565 RGD:728648 NCBI chr22:18,736,957...18,741,207 JBrowse link
G GLRA1 glycine receptor alpha 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:147,245,741...147,348,555
Ensembl chr 5:153,248,488...153,350,567 		JBrowse link
G GLRA2 glycine receptor alpha 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:7,145,794...7,349,911
Ensembl chr  X:14,430,441...14,634,973 		JBrowse link
G GLRB glycine receptor beta involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:149,422,654...149,518,669
Ensembl chr 4:161,236,610...161,333,035 		JBrowse link
G GPR139 G protein-coupled receptor 139 involved_in IEA GOC GO_REF:0000108 NCBI chr16:18,238,117...18,283,773
Ensembl chr16:20,126,515...20,172,343 		JBrowse link
G GPR143 G protein-coupled receptor 143 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:2,357,835...2,398,389
Ensembl chr  X:9,609,598...9,650,075 		JBrowse link
G GPR149 G protein-coupled receptor 149 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:151,393,049...151,493,824
Ensembl chr 3:158,949,110...159,046,551 		JBrowse link
G GPR171 G protein-coupled receptor 171 involved_in IEA GOC GO_REF:0000108 NCBI chr 3:148,226,394...148,231,792
Ensembl chr 3:155,797,293...155,798,251 		JBrowse link
G GPR37 G protein-coupled receptor 37 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:116,727,912...116,751,647
Ensembl chr 7:129,410,458...129,430,292 		JBrowse link
G GPR83 G protein-coupled receptor 83 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:89,380,290...89,405,039
Ensembl chr11:92,868,849...92,889,827 		JBrowse link
G GPR84 G protein-coupled receptor 84 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:34,379,654...34,381,761
Ensembl chr12:35,106,114...35,107,304 		JBrowse link
G GRP gastrin releasing peptide involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:8756537) RGD
TreeGrafter
InterPro
Ensembl
MGI		 PMID:8756537 PMID:12419521 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:728702 NCBI chr18:52,614,169...52,626,427
Ensembl chr18:55,942,263...55,953,188 		JBrowse link
G GRPR gastrin releasing peptide receptor involved_in IEA GOC GO_REF:0000108 NCBI chr  X:8,744,020...8,775,085
Ensembl chr  X:16,099,778...16,131,069 		JBrowse link
G HCRT hypocretin neuropeptide precursor involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000104 NCBI chr17:15,130,581...15,132,024
Ensembl chr17:15,353,203...15,354,594 		JBrowse link
G HCRTR1 hypocretin receptor 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:12697296 GO_REF:0000107 RGD:730811 NCBI chr 1:30,901,772...30,913,633
Ensembl chr 1:31,919,980...31,928,290 		JBrowse link
G HCRTR2 hypocretin receptor 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:9491897 GO_REF:0000107 RGD:728644 NCBI chr 6:54,722,279...54,835,963
Ensembl chr 6:56,327,340...56,469,901 		JBrowse link
G LOC100985913 neuropeptide Y receptor type 4-2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1353743|PMID:10698177) GOC
GOC		 PMID:10698177 GO_REF:0000108 MGI:1353743 NCBI chr10:43,769,740...43,776,225 JBrowse link
G LOC100993088 endothelin-converting enzyme-like 1 ISO RGD PMID:12417666 RGD:628377 NCBI chr2B:119,711,355...119,719,378
Ensembl chr2B:238,630,731...238,637,233 		JBrowse link
G MC2R melanocortin 2 receptor involved_in IEA GOC GO_REF:0000108 NCBI chr18:409,141...442,578
Ensembl chr18:2,608,691...2,609,584 		JBrowse link
G MCHR1 melanin concentrating hormone receptor 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr22:21,577,190...21,581,062
Ensembl chr22:39,673,698...39,677,517 		JBrowse link
G MCHR2 melanin concentrating hormone receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:97,753,053...97,829,175
Ensembl chr 6:101,636,699...101,671,226 		JBrowse link
G MRGPRX3 MAS related GPR family member X3 acts_upstream_of_or_within ISO (MGI:2150459|PMID:11551509) GOC PMID:11551509 MGI:2150459 NCBI chr11:18,183,247...18,189,153
Ensembl chr11:17,870,060...17,871,028 		JBrowse link
G NMBR neuromedin B receptor involved_in IEA GOC GO_REF:0000108 NCBI chr 6:139,842,329...139,915,173
Ensembl chr 6:143,917,130...143,930,363 		JBrowse link
G NMS neuromedin S acts_upstream_of_or_within ISO PMID:15635449 MGI PMID:15635449 RGD:1359746 Ensembl chr2A:101,451,548...101,462,229 JBrowse link
G NMU neuromedin U acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:15635449 MGI
TreeGrafter
Ensembl		 PMID:15635449 GO_REF:0000107 GO_REF:0000118 RGD:1359746 NCBI chr 4:68,299,538...68,340,680
Ensembl chr 4:74,867,364...74,904,965 		JBrowse link
G NMUR1 neuromedin U receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15635449) Ensembl
TreeGrafter
MGI		 PMID:15635449 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:118,773,713...118,854,590
Ensembl chr2B:237,556,920...237,564,268 		JBrowse link
G NMUR2 neuromedin U receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15635449) Ensembl
TreeGrafter
MGI		 PMID:15635449 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:147,811,260...147,825,659
Ensembl chr 5:153,811,055...153,827,176 		JBrowse link
G NPBWR1 neuropeptides B and W receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:49,363,390...49,368,499
Ensembl chr 8:46,745,428...46,746,414 		JBrowse link
G NPBWR2 neuropeptides B and W receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr20:62,022,973...62,023,974 JBrowse link
G NPFFR2 neuropeptide FF receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 4:52,073,462...52,189,443
Ensembl chr 4:58,393,065...58,508,526 		JBrowse link
G NPPA natriuretic peptide A involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373 		JBrowse link
G NPPB natriuretic peptide B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:10,621,416...10,622,960
Ensembl chr 1:11,838,518...11,839,995 		JBrowse link
G NPS neuropeptide S involved_in IEA InterPro GO_REF:0000002 NCBI chr10:124,135,616...124,139,845
Ensembl chr10:128,384,897...128,388,217 		JBrowse link
G NPSR1 neuropeptide S receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:35,274,102...35,494,389
Ensembl chr 7:35,663,335...35,883,988 		JBrowse link
G NPVF neuropeptide VF precursor involved_in ISO
IEA		 RGD
TreeGrafter
InterPro		 PMID:11481330 GO_REF:0000002 GO_REF:0000118 RGD:628488 NCBI chr 7:25,883,679...25,887,596
Ensembl chr 7:25,489,577...25,493,126 		JBrowse link
G NPY neuropeptide Y involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:15703301 PMID:16040808 GO_REF:0000118 RGD:1580180 RGD:1580181 NCBI chr 7:24,963,056...24,970,803
Ensembl chr 7:24,568,041...24,574,657 		JBrowse link
G NPY1R neuropeptide Y receptor Y1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1353743|PMID:10698177) GOC
GOC		 PMID:10698177 GO_REF:0000108 MGI:1353743 NCBI chr 4:155,583,870...155,604,336
Ensembl chr 4:167,372,310...167,381,597 		JBrowse link
G NPY2R neuropeptide Y receptor Y2 involved_in IEA GOC GO_REF:0000108 NCBI chr 4:147,542,551...147,586,397
Ensembl chr 4:159,401,080...159,402,231 		JBrowse link
G NTS neurotensin involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:83,402,313...83,410,356
Ensembl chr12:86,640,720...86,648,745 		JBrowse link
G NTSR1 neurotensin receptor 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:59,100,110...59,151,563
Ensembl chr20:60,392,736...60,446,056 		JBrowse link
G NTSR2 neurotensin receptor 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:82706|PMID:8795617) GOC
TreeGrafter		 PMID:8795617 GO_REF:0000118 MGI:82706 NCBI chr2A:11,645,312...11,657,377 JBrowse link
G OPRD1 opioid receptor delta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8393575) Ensembl
MGI
TreeGrafter		 PMID:8393575 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:28,068,053...28,143,053
Ensembl chr 1:29,112,152...29,163,464 		JBrowse link
G OPRK1 opioid receptor kappa 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:49,650,844...49,677,494
Ensembl chr 8:47,029,313...47,056,577 		JBrowse link
G OPRL1 opioid related nociceptin receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr20:62,004,176...62,017,866 JBrowse link
G OPRM1 opioid receptor mu 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:151,827,323...151,937,658
Ensembl chr 6:156,517,661...157,088,251 		JBrowse link
G PDYN prodynorphin involved_in IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr20:2,092,171...2,108,141
Ensembl chr20:1,856,850...1,872,452 		JBrowse link
G PENK proenkephalin involved_in IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 8:52,864,388...52,870,144
Ensembl chr 8:50,234,170...50,239,949 		JBrowse link
G PNOC prepronociceptin involved_in ISO
IEA		 RGD
TreeGrafter
UniProt
InterPro		 PMID:11826101 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 RGD:633635 NCBI chr 8:27,596,413...27,622,844
Ensembl chr 8:24,796,638...24,822,758 		JBrowse link
G POMC proopiomelanocortin involved_in IEA UniProt
TreeGrafter		 GO_REF:0000043 GO_REF:0000118 NCBI chr2A:25,161,668...25,165,600
Ensembl chr2A:25,258,768...25,262,706 		JBrowse link
G PPY pancreatic polypeptide involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:13,452,839...13,454,513
Ensembl chr17:13,619,936...13,620,788 		JBrowse link
G PRLHR prolactin releasing hormone receptor involved_in IEA GOC GO_REF:0000108 NCBI chr10:114,922,829...115,168,506
Ensembl chr10:118,590,543...118,591,655 		JBrowse link
G PROKR1 prokineticin receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:68,685,129...68,700,372
Ensembl chr2A:69,808,033...69,822,404 		JBrowse link
G PROKR2 prokineticin receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:5,311,043...5,319,148
Ensembl chr20:5,102,997...5,106,655 		JBrowse link
G PYY peptide YY involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:13,390,801...13,442,536
Ensembl chr17:13,608,080...13,608,827 		JBrowse link
G QRFP pyroglutamylated RFamide peptide involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:102,008,900...102,013,194
Ensembl chr 9:130,659,140...130,659,550 		JBrowse link
G QRFPR pyroglutamylated RFamide peptide receptor involved_in IEA GOC GO_REF:0000108 NCBI chr 4:113,537,723...113,591,507
Ensembl chr 4:124,676,059...124,729,754 		JBrowse link
G RAPGEF2 Rap guanine nucleotide exchange factor 2 involved_in ISO (PMID:23800469)
(MGI:5514088|PMID:23800469)		 UniProt PMID:23800469 MGI:5514088 NCBI chr 4:151,419,402...151,680,769
Ensembl chr 4:163,316,396...163,487,495 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868 		JBrowse link
G SCG5 secretogranin V involved_in IEA InterPro GO_REF:0000002 NCBI chr15:11,136,920...11,192,606
Ensembl chr15:29,974,633...30,030,291 		JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:116,297,014...116,477,399
Ensembl chr11:120,222,491...120,402,432 		JBrowse link
G SORT1 sortilin 1 involved_in ISO (PMID:9756851) BHF-UCL PMID:9756851 NCBI chr 1:111,687,119...111,775,339 JBrowse link
G SSTR1 somatostatin receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:68738|PMID:7929134), (PMID:9166719) Ensembl
TreeGrafter
GOC		 PMID:7929134 PMID:9166719 GO_REF:0000107 GO_REF:0000118 MGI:68738 NCBI chr14:18,968,969...18,973,560
Ensembl chr14:37,329,309...37,330,484 		JBrowse link
G SSTR2 somatostatin receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:68738|PMID:7929134), (PMID:9166719) Ensembl
TreeGrafter
MGI		 PMID:7929134 PMID:9166719 GO_REF:0000107 GO_REF:0000118 MGI:68738 NCBI chr17:67,093,013...67,099,086
Ensembl chr17:72,553,506...72,554,615 		JBrowse link
G SSTR3 somatostatin receptor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:18,116,993...18,125,170
Ensembl chr22:35,954,232...35,955,488 		JBrowse link
G SSTR4 somatostatin receptor 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:22,982,009...22,986,058
Ensembl chr20:23,333,320...23,334,766 		JBrowse link
G TAC1 tachykinin precursor 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 7:89,675,834...89,684,391
Ensembl chr 7:103,257,501...103,266,389 		JBrowse link
G TYRO3 TYRO3 protein tyrosine kinase acts_upstream_of_or_within ISO (PMID:9331176) MGI PMID:9331176 NCBI chr15:20,499,789...20,520,152
Ensembl chr15:38,739,509...38,760,288 		JBrowse link
G UCN urocortin ISO RGD PMID:11784785 RGD:70397 NCBI chr2A:27,309,458...27,311,268
Ensembl chr2A:27,397,295...27,397,669 		JBrowse link
G UTS2R urotensin 2 receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:76,783,432...76,788,639
Ensembl chr17:82,592,312...82,593,702 		JBrowse link
galanin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALR2 galanin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:70,019,383...70,028,689
Ensembl chr17:75,578,072...75,580,806 		JBrowse link
G GALR3 galanin receptor 3 involved_in ISO (PMID:9832121) GO_Central PMID:9832121 NCBI chr22:18,736,957...18,741,207 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16447
    cellular process 15499
      signal transduction 5443
        G protein-coupled receptor signaling pathway 1066
          neuropeptide signaling pathway 84
            galanin-activated signaling pathway 2
Path 2
Term Annotations click to browse term
  biological_process 16447
    biological regulation 11463
      regulation of biological process 11110
        signaling 5940
          signal transduction 5443
            G protein-coupled receptor signaling pathway 1066
              neuropeptide signaling pathway 84
                galanin-activated signaling pathway 2
paths to the root