NMBR (neuromedin B receptor) - Rat Genome Database

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Gene: NMBR (neuromedin B receptor) Pan paniscus
Analyze
Symbol: NMBR
Name: neuromedin B receptor
RGD ID: 12022517
Description: ENCODES a protein that exhibits neuropeptide receptor activity (ortholog); INVOLVED IN antiviral innate immune response (inferred); bombesin receptor signaling pathway (inferred); G protein-coupled receptor signaling pathway (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); Familial Behcet-Like Autoinflammatory Syndrome (ortholog); FOUND IN cytosol (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neuromedin-B receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25162,033,859 - 162,121,628 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16159,928,484 - 160,016,139 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06139,842,329 - 139,915,173 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16143,915,784 - 143,988,667 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6143,917,130 - 143,930,363 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
membrane  (IEA)
plasma membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NMBR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25162,033,859 - 162,121,628 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16159,928,484 - 160,016,139 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06139,842,329 - 139,915,173 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16143,915,784 - 143,988,667 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6143,917,130 - 143,930,363 (-)Ensemblpanpan1.1panPan2
NMBR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386142,074,484 - 142,147,122 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6142,058,330 - 142,147,122 (-)EnsemblGRCh38hg38GRCh38
GRCh376142,395,621 - 142,468,259 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366142,438,438 - 142,451,629 (-)NCBINCBI36Build 36hg18NCBI36
Build 346142,438,437 - 142,451,629NCBI
Celera6143,137,223 - 143,150,416 (-)NCBICelera
Cytogenetic Map6q24.1NCBI
HuRef6139,962,598 - 139,975,792 (-)NCBIHuRef
CHM1_16142,658,985 - 142,672,176 (-)NCBICHM1_1
T2T-CHM13v2.06143,260,409 - 143,339,214 (-)NCBIT2T-CHM13v2.0
Nmbr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391014,634,894 - 14,647,202 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1014,581,335 - 14,646,594 (+)EnsemblGRCm39 Ensembl
GRCm381014,759,356 - 14,771,458 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1014,705,591 - 14,770,850 (+)EnsemblGRCm38mm10GRCm38
MGSCv371014,480,095 - 14,490,362 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361014,450,487 - 14,460,754 (+)NCBIMGSCv36mm8
Celera1014,666,248 - 14,676,488 (+)NCBICelera
Cytogenetic Map10A2NCBI
cM Map105.5NCBI
Nmbr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8110,942,476 - 10,966,174 (+)NCBIGRCr8
mRatBN7.219,115,033 - 9,146,081 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl19,134,889 - 9,145,462 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx18,854,053 - 8,864,609 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0114,855,973 - 14,866,529 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.019,108,728 - 9,119,316 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.018,933,744 - 8,945,850 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl18,933,831 - 8,944,987 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0110,550,181 - 10,560,850 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.419,598,651 - 9,613,018 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.119,614,247 - 9,627,257 (+)NCBI
Celera17,611,477 - 7,622,026 (+)NCBICelera
RH 3.4 Map1128.12RGD
Cytogenetic Map1p13NCBI
Nmbr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543618,116,274 - 18,127,045 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543618,116,274 - 18,127,045 (+)NCBIChiLan1.0ChiLan1.0
NMBR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1133,772,687 - 33,858,112 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl133,772,690 - 33,801,720 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha134,671,595 - 34,756,297 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0133,947,794 - 34,032,604 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl133,947,114 - 33,976,148 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1133,818,335 - 33,903,030 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0133,700,066 - 33,784,852 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0134,011,044 - 34,095,793 (-)NCBIUU_Cfam_GSD_1.0
Nmbr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946128,751,204 - 128,762,908 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366253,873,062 - 3,883,172 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366253,872,786 - 3,883,478 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NMBR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl122,972,885 - 22,988,179 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1122,972,049 - 22,989,188 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,808,851 - 25,823,914 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NMBR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11331,170,727 - 31,193,830 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1331,171,670 - 31,192,008 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660403,248,199 - 3,315,563 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nmbr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475312,017,711 - 12,028,673 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475312,017,650 - 12,029,360 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000065138   ⟹   ENSPPAP00000042208
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6143,917,130 - 143,930,363 (-)Ensembl
RefSeq Acc Id: XM_003827713   ⟹   XP_003827761
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25162,048,816 - 162,064,022 (-)NCBI
NHGRI_mPanPan16159,943,443 - 159,958,664 (-)NCBI
Mhudiblu_PPA_v06139,842,329 - 139,857,535 (-)NCBI
PanPan1.16143,916,029 - 143,930,363 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024929158   ⟹   XP_024784926
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25162,048,816 - 162,121,628 (-)NCBI
NHGRI_mPanPan16159,943,443 - 160,016,139 (-)NCBI
Mhudiblu_PPA_v06139,842,329 - 139,915,173 (-)NCBI
PanPan1.16143,916,029 - 143,988,661 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034962963   ⟹   XP_034818854
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25162,048,822 - 162,062,787 (-)NCBI
NHGRI_mPanPan16159,943,449 - 159,957,427 (-)NCBI
Mhudiblu_PPA_v06139,842,335 - 139,856,300 (-)NCBI
RefSeq Acc Id: XM_055114162   ⟹   XP_054970137
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25162,033,859 - 162,064,022 (-)NCBI
NHGRI_mPanPan16159,928,484 - 159,958,664 (-)NCBI
RefSeq Acc Id: XM_055114163   ⟹   XP_054970138
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25162,048,822 - 162,117,005 (-)NCBI
NHGRI_mPanPan16159,943,449 - 160,011,646 (-)NCBI
RefSeq Acc Id: XP_003827761   ⟸   XM_003827713
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CMF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024784926   ⟸   XM_024929158
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_034818854   ⟸   XM_034962963
- Peptide Label: isoform X4
Ensembl Acc Id: ENSPPAP00000042208   ⟸   ENSPPAT00000065138
RefSeq Acc Id: XP_054970137   ⟸   XM_055114162
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054970138   ⟸   XM_055114163
- Peptide Label: isoform X4

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043688 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000065138.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro Bombsn_rcpt-like UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  NeuroB_rcpt UniProtKB/TrEMBL
KEGG Report pps:100973950 UniProtKB/TrEMBL
NCBI Gene NMBR ENTREZGENE
PANTHER LEUCOKININ RECEPTOR-RELATED UniProtKB/TrEMBL
  NEUROMEDIN-B RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS BOMBESINR UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
  NEUROMEDINBR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A2R9CMF6 ENTREZGENE, UniProtKB/TrEMBL