NMBR (neuromedin B receptor) - Rat Genome Database

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Gene: NMBR (neuromedin B receptor) Chlorocebus sabaeus
Analyze
Symbol: NMBR
Name: neuromedin B receptor
RGD ID: 18502307
Description: ENCODES a protein that exhibits neuropeptide receptor activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); negative regulation of interleukin-6 production (ortholog); positive regulation of interferon-alpha production (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Familial Behcet-Like Autoinflammatory Syndrome (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neuromedin-B receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11331,170,727 - 31,193,830 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1331,171,670 - 31,192,008 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660403,248,199 - 3,315,563 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)
membrane  (IEA)
plasma membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
NMBR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11331,170,727 - 31,193,830 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1331,171,670 - 31,192,008 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660403,248,199 - 3,315,563 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
NMBR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386142,074,484 - 142,147,122 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6142,058,330 - 142,147,122 (-)EnsemblGRCh38hg38GRCh38
GRCh376142,395,621 - 142,468,259 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366142,438,438 - 142,451,629 (-)NCBINCBI36Build 36hg18NCBI36
Build 346142,438,437 - 142,451,629NCBI
Celera6143,137,223 - 143,150,416 (-)NCBICelera
Cytogenetic Map6q24.1NCBI
HuRef6139,962,598 - 139,975,792 (-)NCBIHuRef
CHM1_16142,658,985 - 142,672,176 (-)NCBICHM1_1
T2T-CHM13v2.06143,260,409 - 143,339,214 (-)NCBIT2T-CHM13v2.0
Nmbr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391014,634,894 - 14,647,202 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1014,581,335 - 14,646,594 (+)EnsemblGRCm39 Ensembl
GRCm381014,759,356 - 14,771,458 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1014,705,591 - 14,770,850 (+)EnsemblGRCm38mm10GRCm38
MGSCv371014,480,095 - 14,490,362 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361014,450,487 - 14,460,754 (+)NCBIMGSCv36mm8
Celera1014,666,248 - 14,676,488 (+)NCBICelera
Cytogenetic Map10A2NCBI
cM Map105.5NCBI
Nmbr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8110,942,476 - 10,966,174 (+)NCBIGRCr8
mRatBN7.219,115,033 - 9,146,081 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl19,134,889 - 9,145,462 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx18,854,053 - 8,864,609 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0114,855,973 - 14,866,529 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.019,108,728 - 9,119,316 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.018,933,744 - 8,945,850 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl18,933,831 - 8,944,987 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0110,550,181 - 10,560,850 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.419,598,651 - 9,613,018 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.119,614,247 - 9,627,257 (+)NCBI
Celera17,611,477 - 7,622,026 (+)NCBICelera
RH 3.4 Map1128.12RGD
Cytogenetic Map1p13NCBI
Nmbr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543618,116,274 - 18,127,045 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543618,116,274 - 18,127,045 (+)NCBIChiLan1.0ChiLan1.0
NMBR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25162,033,859 - 162,121,628 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16159,928,484 - 160,016,139 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06139,842,329 - 139,915,173 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16143,915,784 - 143,988,667 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6143,917,130 - 143,930,363 (-)Ensemblpanpan1.1panPan2
NMBR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1133,772,687 - 33,858,112 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl133,772,690 - 33,801,720 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha134,671,595 - 34,756,297 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0133,947,794 - 34,032,604 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl133,947,114 - 33,976,148 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1133,818,335 - 33,903,030 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0133,700,066 - 33,784,852 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0134,011,044 - 34,095,793 (-)NCBIUU_Cfam_GSD_1.0
Nmbr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946128,751,204 - 128,762,908 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366253,873,062 - 3,883,172 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366253,872,786 - 3,883,478 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NMBR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl122,972,885 - 22,988,179 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1122,972,049 - 22,989,188 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,808,851 - 25,823,914 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Nmbr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475312,017,711 - 12,028,673 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475312,017,650 - 12,029,360 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 11 16
Below cutoff 18 6 40

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000015143   ⟹   ENSCSAP00000013092
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1331,171,670 - 31,192,008 (+)Ensembl
RefSeq Acc Id: XM_008006841   ⟹   XP_008005032
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11331,170,727 - 31,193,830 (+)NCBI
Vero_WHO_p1.0NW_0236660403,248,199 - 3,315,563 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038000810   ⟹   XP_037856738
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660403,248,199 - 3,315,563 (+)NCBI
RefSeq Acc Id: XM_038000812   ⟹   XP_037856740
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660403,248,199 - 3,315,563 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008005032 (Get FASTA)   NCBI Sequence Viewer  
  XP_037856738 (Get FASTA)   NCBI Sequence Viewer  
  XP_037856740 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000013092
  ENSCSAP00000013092.1
Reference Protein Sequences
RefSeq Acc Id: XP_008005032   ⟸   XM_008006841
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RWV3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000013092   ⟸   ENSCSAT00000015143
RefSeq Acc Id: XP_037856738   ⟸   XM_038000810
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037856740   ⟸   XM_038000812
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017049 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015143.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro Bombsn_rcpt-like UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  NeuroB_rcpt UniProtKB/TrEMBL
KEGG Report csab:103240268 UniProtKB/TrEMBL
NCBI Gene NMBR ENTREZGENE
PANTHER LEUCOKININ RECEPTOR-RELATED UniProtKB/TrEMBL
  NEUROMEDIN-B RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS BOMBESINR UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
  NEUROMEDINBR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0D9RWV3 ENTREZGENE, UniProtKB/TrEMBL