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ONTOLOGY REPORT - ANNOTATIONS

Term:single strand break repair
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Accession:GO:0000012 term browser browse the term
Definition:The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair.


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single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APLF aprataxin and PNKP like factor involved_in IMP (PMID:17396150) UniProt PMID:17396150 NCBI chr 2:68,467,585...68,580,162
Ensembl chr 2:68,467,572...68,655,862 		JBrowse link
G APTX aprataxin involved_in IEA
IBA
IMP
IDA		 (PMID:15044383)
(PMID:14755728), (PMID:17519253)		 Ensembl
GO_Central
TreeGrafter
UniProt		 PMID:14755728 PMID:15044383 PMID:17519253 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:32,972,616...33,025,120
Ensembl chr 9:32,886,601...33,025,130 		JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor involved_in IDA (PMID:29545921) UniProt PMID:29545921 NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,168...49,539,538 		JBrowse link
G ERCC8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit involved_in IDA (PMID:29545921) UniProt PMID:29545921 NCBI chr 5:60,866,454...60,945,070
Ensembl chr 5:60,866,454...60,945,073 		JBrowse link
G L34079.1 novel protein involved_in IEA InterPro GO_REF:0000002 Ensembl chr19:43,554,692...43,593,036 JBrowse link
G LIG4 DNA ligase 4 involved_in IDA (PMID:8798671) UniProt PMID:8798671 NCBI chr13:108,207,442...108,218,349
Ensembl chr13:108,207,439...108,218,368 		JBrowse link
G SIRT1 sirtuin 1 involved_in IMP (PMID:20097625) UniProt PMID:20097625 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G TDP1 tyrosyl-DNA phosphodiesterase 1 involved_in
acts_upstream_of_or_within		 IMP
ISO
IDA		 (PMID:17600775)
(PMID:17914460), (PMID:17948061)
(PMID:15811850)		 UniProt
MGI		 PMID:15811850 PMID:17600775 PMID:17914460 PMID:17948061 NCBI chr14:89,954,968...90,044,764
Ensembl chr14:89,954,939...90,044,764 		JBrowse link
G TNP1 transition protein 1 involved_in IDA (PMID:12743712) UniProt PMID:12743712 NCBI chr 2:216,859,458...216,860,064
Ensembl chr 2:216,859,458...216,860,064 		JBrowse link
G XNDC1N XRCC1 N-terminal domain containing 1, N-terminal like involved_in IEA InterPro GO_REF:0000002 NCBI chr11:71,865,509...71,928,594
Ensembl chr11:71,865,504...71,928,654 		JBrowse link
G XNDC1N-ZNF705EP-ALG1L9P XNDC1N-ZNF705EP-ALG1L9P readthrough involved_in IEA InterPro GO_REF:0000002 NCBI chr11:71,804,981...71,928,594
Ensembl chr11:71,804,997...71,928,656 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
negative regulation of telomere single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TERF2 telomeric repeat binding factor 2 involved_in NAS (PMID:17395247) BHF-UCL PMID:17395247 NCBI chr16:69,355,567...69,386,007
Ensembl chr16:69,355,567...69,408,571 		JBrowse link
positive regulation of single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IGI (PMID:28002403) UniProt PMID:28002403 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 involved_in IMP
IEA
IGI		 (PMID:28002403) UniProt
Ensembl		 PMID:28002403 GO_REF:0000107 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
regulation of single strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARP1 poly(ADP-ribose) polymerase 1 acts_upstream_of_or_within ISO (PMID:25378300) MGI PMID:25378300 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19670
    response to stimulus 10180
      response to stress 4600
        cellular response to stress 2150
          DNA damage response 964
            DNA repair 647
              single strand break repair 14
                negative regulation of single strand break repair + 1
                positive regulation of single strand break repair + 2
                regulation of single strand break repair + 3
                single-strand break repair via homologous recombination + 0
                telomere single strand break repair + 1
Path 2
Term Annotations click to browse term
  biological_process 19670
    metabolic process 12471
      organic substance metabolic process 11974
        organic cyclic compound metabolic process 7070
          nucleobase-containing compound metabolic process 6539
            nucleic acid metabolic process 5935
              DNA metabolic process 1074
                DNA repair 647
                  single strand break repair 14
                    negative regulation of single strand break repair + 1
                    positive regulation of single strand break repair + 2
                    regulation of single strand break repair + 3
                    single-strand break repair via homologous recombination + 0
                    telomere single strand break repair + 1
paths to the root