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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of double-strand break repair via nonhomologous end joining
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Accession:GO:2001033 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
Synonyms:exact_synonym: negative regulation of NHEJ


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negative regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aunip aurora kinase A and ninein interacting protein involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:29042561)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:29042561 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:146,722,329...146,734,924
Ensembl chr 5:146,722,337...146,736,501 		JBrowse link
G Cyren cell cycle regulator of NHEJ involved_in ISO
IEA
ISS		 (PMID:28959974)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:28959974 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:63,547,311...63,553,394
Ensembl chr 4:63,547,335...63,551,602 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) RGD PMID:25820262 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19549901)		 UniProt
RGD		 PMID:19549901 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hsf1 heat shock transcription factor 1 involved_in ISO (PMID:26359349) RGD PMID:26359349 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:24316220)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24316220 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Nudt16l1 nudix hydrolase 16 like 1 involved_in ISO (PMID:28241136) RGD PMID:28241136 NCBI chr10:10,636,174...10,638,090
Ensembl chr10:10,636,174...10,688,370 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20228
    response to stimulus 10821
      negative regulation of response to stimulus 1880
        negative regulation of DNA repair 38
          negative regulation of double-strand break repair 37
            negative regulation of double-strand break repair via nonhomologous end joining 7
Path 2
Term Annotations click to browse term
  biological_process 20228
    cellular process 19289
      metabolic process 12069
        primary metabolic process 10685
          nucleobase-containing compound metabolic process 5842
            nucleic acid metabolic process 5233
              DNA metabolic process 972
                DNA repair 558
                  regulation of DNA repair 174
                    negative regulation of DNA repair 38
                      negative regulation of double-strand break repair 37
                        negative regulation of double-strand break repair via nonhomologous end joining 7
paths to the root