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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of T-helper 17 cell differentiation
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Accession:GO:2000320 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation.
Synonyms:related_synonym: negative regulation of T-helper 17 cell development


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negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in ISO (MGI:5565031|PMID:24463518) RGD PMID:24463518 MGI:5565031 NCBI chr 1:198,148,999...198,151,406
Ensembl chr 1:198,148,999...198,151,406 		JBrowse link
G Foxp3 forkhead box P3 involved_in ISO (PMID:23169781) RGD PMID:23169781 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Il2 interleukin 2 involved_in ISO RNAcentral:URS000039ED8D_10090 (MGI:5634593|PMID:25642768) RGD PMID:25642768 MGI:5634593 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:18792410) RGD PMID:18792410 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Pf4 platelet factor 4 IDA RGD PMID:24986443 RGD:329901907 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839 		JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr 3:21,121,531...21,186,711
Ensembl chr 3:21,110,679...21,179,933 		JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5634593|PMID:25642768)		 Ensembl
RGD		 PMID:25642768 GO_REF:0000107 MGI:5634593 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:4868293|PMID:21151104) RGD PMID:21151104 MGI:4868293 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within ISO MGI:3530739 (PMID:23034280) RGD PMID:23034280 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO		 GO_REF:0000024
(MGI:6142401|PMID:25282160)		 UniProt
RGD		 PMID:25282160 GO_REF:0000024 MGI:6142401 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Loxl3 lysyl oxidase-like 3 involved_in ISO (MGI:5825383|PMID:28065600)
(PMID:28065600)		 RGD PMID:28065600 MGI:5825383 NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:4868293|PMID:21151104) RGD PMID:21151104 MGI:4868293 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in ISO (MGI:5551556|PMID:24107315) RGD PMID:24107315 MGI:5551556 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    immune system process 2822
      immune effector process 725
        negative regulation of immune effector process 142
          negative regulation of T-helper cell differentiation 21
            negative regulation of T-helper 17 cell differentiation 13
              negative regulation of T-helper 17 cell lineage commitment 3
Path 2
Term Annotations click to browse term
  biological_process 19692
    cellular process 18168
      cellular developmental process 4695
        cell differentiation 4694
          cell development 3269
            hemopoiesis 1061
              leukocyte differentiation 674
                mononuclear cell differentiation 544
                  lymphocyte differentiation 447
                    T cell differentiation 324
                      T cell differentiation involved in immune response 89
                        alpha-beta T cell differentiation involved in immune response 81
                          CD4-positive, alpha-beta T cell differentiation involved in immune response 80
                            T-helper cell differentiation 78
                              regulation of T-helper cell differentiation 46
                                negative regulation of T-helper cell differentiation 21
                                  negative regulation of T-helper 17 cell differentiation 13
                                    negative regulation of T-helper 17 cell lineage commitment 3
paths to the root