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ONTOLOGY REPORT - ANNOTATIONS
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Term:
negative regulation of T-helper 17 cell lineage commitment
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Accession:
GO:2000329
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Definition:
Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell lineage commitment.
Synonyms:
exact_synonym:
negative regulation of T-helper 17 cell fate commitment; negative regulation of Th17 cell lineage commitment; negative regulation of Th17 fate commitment
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reference
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Rat (3)
Mouse (3)
Human (3)
Chinchilla (3)
Bonobo (3)
Dog (3)
Squirrel (3)
Pig (3)
All
Genes (3)
negative regulation of T-helper 17 cell lineage commitment
Symbol
Object Name
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Loxl3
lysyl oxidase-like 3
ISO
(MGI:5825383|PMID:28065600)
RGD
PMID:28065600
MGI:5825383
NCBI chr 4:113,866,782...113,883,713
Ensembl chr 4:113,866,804...113,883,477
G
Tbx21
T-box transcription factor 21
ISO
(MGI:4868293|PMID:21151104)
RGD
PMID:21151104
MGI:4868293
NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
G
Tnfsf18
TNF superfamily member 18
ISO
(MGI:5551556|PMID:24107315)
RGD
PMID:24107315
MGI:5551556
NCBI chr13:79,378,412...79,388,687
Ensembl chr13:79,378,733...79,388,498
Term paths to the root
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Path 1
Term
Annotations
biological_process
20045
developmental process
6824
regulation of developmental process
2652
regulation of cell fate commitment
35
negative regulation of cell fate commitment
16
negative regulation of T-helper 17 cell lineage commitment
3
Path 2
Term
Annotations
biological_process
20045
developmental process
6824
anatomical structure development
6290
multicellular organism development
5766
system development
5298
immune system development
1081
hematopoietic or lymphoid organ development
1016
hemopoiesis
964
leukocyte differentiation
601
mononuclear cell differentiation
467
lymphocyte differentiation
414
T cell differentiation
294
T cell differentiation involved in immune response
79
alpha-beta T cell differentiation involved in immune response
71
CD4-positive, alpha-beta T cell differentiation involved in immune response
70
T-helper cell differentiation
68
regulation of T-helper cell differentiation
40
negative regulation of T-helper cell differentiation
19
negative regulation of T-helper 17 cell differentiation
11
negative regulation of T-helper 17 cell lineage commitment
3