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ONTOLOGY REPORT - ANNOTATIONS

Term:intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
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Accession:GO:1990127 term browser browse the term
Definition:The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered.


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intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:98834|MGI:99702 (PMID:16571598)		 Ensembl
RGD		 PMID:16571598 GO_REF:0000107 NCBI chr 6:124,472,317...124,502,497 JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:98834|MGI:99702 (PMID:16571598)		 Ensembl
RGD		 PMID:16571598 GO_REF:0000107 NCBI chr 6:124,472,317...124,502,497 JBrowse link
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tifab TIFA inhibitor acts_upstream_of_or_within ISO (PMID:32101751) RGD PMID:32101751 NCBI chr17:8,433,406...8,436,541 JBrowse link
G Usp15 ubiquitin specific peptidase 15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:32101751)		 Ensembl
RGD		 PMID:32101751 GO_REF:0000107 NCBI chr 7:58,756,714...58,848,778 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    response to stimulus 11014
      response to abiotic stimulus 1597
        response to osmotic stress 119
          cellular response to osmotic stress 73
            intrinsic apoptotic signaling pathway in response to osmotic stress 11
              intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 3
                negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 0
                regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 3
Path 2
Term Annotations click to browse term
  biological_process 20536
    biological regulation 13822
      regulation of biological process 13376
        signaling 7809
          signal transduction 7251
            apoptotic signaling pathway 680
              intrinsic apoptotic signaling pathway 341
                intrinsic apoptotic signaling pathway by p53 class mediator 87
                  intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 3
                    negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                    positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 0
                    regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 3
paths to the root