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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of ERBB signaling pathway
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Accession:GO:1901186 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway.
Synonyms:exact_synonym: activation of EGF receptor family signaling pathway;   activation of ERBB signalling pathway;   activation of ErbB signaling;   positive regulation of EGF receptor family signaling pathway;   positive regulation of ERBB signalling pathway;   positive regulation of ErbB signaling;   up regulation of EGF receptor family signaling pathway;   up regulation of ERBB signaling pathway;   up regulation of ERBB signalling pathway;   up regulation of ErbB signaling;   upregulation of EGF receptor family signaling pathway;   upregulation of ERBB signaling pathway;   upregulation of ERBB signalling pathway;   upregulation of ErbB signaling
 narrow_synonym: activation of ERBB signaling pathway
 related_synonym: activation of EGFR family signaling pathway;   positive regulation of EGFR family signaling pathway;   up regulation of EGFR family signaling pathway;   upregulation of EGFR family signaling pathway



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positive regulation of ERBB signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:84,060,417...84,286,008
Ensembl chr 3:84,064,440...84,286,360
JBrowse link
positive regulation of epidermal growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in
acts_upstream_of
IEA
ISO
(MGI:3829110|PMID:18625725) Ensembl
BHF-UCL
PMID:18625725 GO_REF:0000107 MGI:3829110 NCBI chr17:6,589,874...6,638,788
Ensembl chr17:6,589,878...6,638,731
JBrowse link
G ADRA2A adrenoceptor alpha 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:22,366,989...22,392,163
Ensembl chr28:22,367,780...22,370,684
JBrowse link
G AFAP1L2 actin filament associated protein 1 like 2 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr28:25,137,235...25,228,454
Ensembl chr28:25,133,296...25,194,431
JBrowse link
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:31,303,784...31,316,752
Ensembl chr14:31,305,567...31,316,686
JBrowse link
G AGT angiotensinogen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880
JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) AgBase PMID:23389627 NCBI chr 7:41,835,322...41,850,488
Ensembl chr 7:41,812,353...41,850,488
JBrowse link
G B9D2 B9 domain containing 2 acts_upstream_of ISO (PMID:18625725) BHF-UCL PMID:18625725 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G CCDC88A coiled-coil domain containing 88A involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:56,167,907...56,300,974
Ensembl chr10:56,170,479...56,300,908
JBrowse link
G CNOT9 CCR4-NOT transcription complex subunit 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:25,186,928...25,213,255
Ensembl chr37:25,187,066...25,212,642
JBrowse link
G DGKD diacylglycerol kinase delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:44,851,827...44,961,352
Ensembl chr25:44,851,493...44,961,364
JBrowse link
G ESR1 estrogen receptor 1 ISO RGD PMID:17928626 RGD:5128669 NCBI chr 1:42,081,952...42,368,544
Ensembl chr 1:42,081,969...42,368,544
JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:17928626 RGD:5128669 NCBI chr 8:38,645,917...38,715,347
Ensembl chr 8:38,645,430...38,702,691
JBrowse link
G FAM83B family with sequence similarity 83 member B involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:22,256,452...22,341,919
Ensembl chr12:22,257,110...22,338,231
JBrowse link
G FASLG Fas ligand ISO RGD PMID:18471522 RGD:2315731 NCBI chr 7:26,335,837...26,344,224
Ensembl chr 7:26,335,846...26,344,224
JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in ISO
IEA
RGD
Ensembl
PMID:20445128 GO_REF:0000107 RGD:4892084 NCBI chr 6:15,792,072...15,796,922
Ensembl chr 6:15,792,897...15,794,051
JBrowse link
G HAP1 huntingtin associated protein 1 involved_in ISO PMID:12890790 UniProt PMID:12890790 RGD:10047165 NCBI chr 9:21,065,770...21,074,462
Ensembl chr 9:21,065,846...21,072,991
JBrowse link
G HIP1 huntingtin interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,957,760...7,115,676
Ensembl chr 6:6,961,053...7,115,618
JBrowse link
G HIP1R huntingtin interacting protein 1 related involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:6,623,583...6,639,107
Ensembl chr26:6,624,791...6,637,659
JBrowse link
G MIR29A microRNA mir-29a involved_in ISO (PMID:25058496) FlyBase PMID:25058496 NCBI chr14:6,184,844...6,184,903
Ensembl chr14:6,184,830...6,184,916
JBrowse link
G MMP9 matrix metallopeptidase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293
JBrowse link
G NEU3 neuraminidase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:23,456,424...23,484,872 JBrowse link
G PDE6G phosphodiesterase 6G involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
(PMID:11502744) GO_Central
MGI
TreeGrafter
PMID:11502744 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:525,123...529,406
Ensembl chr 9:526,577...529,526
JBrowse link
G PDE6H phosphodiesterase 6H involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11502744) TreeGrafter
MGI
PMID:11502744 GO_REF:0000118 NCBI chr27:31,640,731...31,664,494
Ensembl chr27:31,640,737...31,664,401
JBrowse link
G PLAUR plasminogen activator, urokinase receptor involved_in ISO (PMID:22984561) CACAO PMID:22984561 NCBI chr 1:111,476,804...111,490,876
Ensembl chr 1:111,476,893...111,490,880
JBrowse link
G RALA RAS like proto-oncogene A involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:10,022,490...10,047,583
Ensembl chr18:10,024,311...10,039,183
JBrowse link
G RALB RAS like proto-oncogene B involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:29,820,006...29,868,345
Ensembl chr19:29,768,359...29,868,335
JBrowse link
G SHKBP1 SH3KBP1 binding protein 1 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 1:113,154,285...113,165,988
Ensembl chr 1:113,154,460...113,165,992
JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO RGD PMID:8577724 RGD:1581110 NCBI chr17:31,007,940...31,181,569
Ensembl chr17:31,009,257...31,142,063
JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in ISO (PMID:15962011) MGI PMID:15962011 NCBI chr22:33,366,139...33,371,102
Ensembl chr22:33,366,931...33,367,878
JBrowse link
G TGFB1 transforming growth factor beta 1 acts_upstream_of
involved_in
ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
positive regulation of ERBB3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RTN4 reticulon 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:55,884,452...55,954,476
Ensembl chr10:55,885,125...55,936,574
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17925
    cellular process 16910
      signal transduction 6317
        positive regulation of signal transduction 1712
          positive regulation of ERBB signaling pathway 32
            positive regulation of ERBB3 signaling pathway 1
            positive regulation of epidermal growth factor receptor signaling pathway + 30
Path 2
Term Annotations click to browse term
  biological_process 17925
    biological regulation 12446
      regulation of biological process 12082
        regulation of cellular process 11572
          signal transduction 6317
            cell surface receptor signaling pathway 2807
              enzyme-linked receptor protein signaling pathway 1041
                cell surface receptor protein tyrosine kinase signaling pathway 654
                  ERBB signaling pathway 132
                    regulation of ERBB signaling pathway 71
                      positive regulation of ERBB signaling pathway 32
                        positive regulation of ERBB3 signaling pathway 1
                        positive regulation of epidermal growth factor receptor signaling pathway + 30
paths to the root