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ONTOLOGY REPORT - ANNOTATIONS

Term:precatalytic spliceosome
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Accession:GO:0071011 term browser browse the term
Definition:A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.
Synonyms:narrow_synonym: mammalian spliceosomal complex B;   mammalian spliceosomal complex B1;   yeast spliceosomal complex A2-1


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precatalytic spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100687873 small nuclear ribonucleoprotein polypeptide E pseudogene part_of IBA GO_Central GO_REF:0000033 NCBI chr 8:15,582,856...15,583,331 JBrowse link
G LOC100855556 U6 snRNA-associated Sm-like protein LSm8 part_of IBA GO_Central GO_REF:0000033 NCBI chr 3:3,633,656...3,634,121 JBrowse link
G LOC102154080 U6 snRNA-associated Sm-like protein LSm3 part_of IBA GO_Central GO_REF:0000033 NCBI chr15:14,519,325...14,519,728 JBrowse link
G LOC111098242 small nuclear ribonucleoprotein G-like part_of IBA GO_Central GO_REF:0000033 NCBI chr12:6,244,678...6,245,140 JBrowse link
G LOC119865017 U6 snRNA-associated Sm-like protein LSm3 part_of IBA GO_Central GO_REF:0000033
G LOC609886 NHP2-like protein 1 part_of IBA GO_Central GO_REF:0000033 NCBI chr  X:99,519,362...99,520,465 JBrowse link
G LSM2 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated part_of IBA GO_Central GO_REF:0000033 NCBI chr12:1,270,328...1,279,269 JBrowse link
G LSM3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated part_of IBA GO_Central GO_REF:0000033 NCBI chr20:4,328,930...4,342,731
Ensembl chr20:4,329,038...4,342,859 		JBrowse link
G LSM3 part_of IBA GO_Central GO_REF:0000033
G LSM3 part_of IBA GO_Central GO_REF:0000033
G LSM8 LSM8 homolog, U6 small nuclear RNA associated part_of IBA GO_Central GO_REF:0000033 NCBI chr14:56,908,344...56,916,512 JBrowse link
G LSM8 LSM8 homolog, U6 small nuclear RNA associated part_of IBA GO_Central GO_REF:0000033 NCBI chr18:55,715,008...55,715,562
Ensembl chr18:55,715,105...55,715,395 		JBrowse link
G PHF5A PHD finger protein 5A part_of IBA GO_Central GO_REF:0000033 NCBI chr10:23,798,854...23,809,024
Ensembl chr10:23,798,969...23,808,865 		JBrowse link
G PRPF31 pre-mRNA processing factor 31 part_of IBA GO_Central GO_REF:0000033 NCBI chr 1:103,073,359...103,090,652
Ensembl chr 1:103,073,380...103,090,652 		JBrowse link
G PRPF38A pre-mRNA processing factor 38A part_of IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr15:8,950,621...8,965,205
Ensembl chr15:8,950,805...8,965,085 		JBrowse link
G PRPF38B pre-mRNA processing factor 38B part_of IBA GO_Central GO_REF:0000033 NCBI chr 6:43,044,322...43,052,622
Ensembl chr 6:42,948,236...43,053,027 		JBrowse link
G RBMX2 RNA binding motif protein X-linked 2 part_of IBA GO_Central GO_REF:0000033 NCBI chr  X:101,533,732...101,547,147
Ensembl chr  X:101,533,835...101,544,552 		JBrowse link
G SF3B2 splicing factor 3b subunit 2 part_of IBA GO_Central GO_REF:0000033 NCBI chr18:51,197,924...51,212,397
Ensembl chr18:51,197,939...51,212,354 		JBrowse link
G SF3B4 splicing factor 3b subunit 4 part_of IBA GO_Central GO_REF:0000033 NCBI chr17:59,208,989...59,214,643
Ensembl chr17:59,208,990...59,213,991 		JBrowse link
G SF3B5 splicing factor 3b subunit 5 part_of IEA
IBA		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr 1:35,558,249...35,558,998
Ensembl chr 1:35,558,599...35,558,859 		JBrowse link
G SNRPD1 small nuclear ribonucleoprotein D1 polypeptide part_of IBA GO_Central GO_REF:0000033 NCBI chr 7:66,407,313...66,421,193
Ensembl chr 7:66,407,313...66,421,194 		JBrowse link
G SNRPD2 small nuclear ribonucleoprotein D2 polypeptide part_of IBA GO_Central GO_REF:0000033 NCBI chr 1:109,891,253...109,896,712
Ensembl chr 1:109,891,223...109,896,711 		JBrowse link
G SNRPD3 small nuclear ribonucleoprotein D3 polypeptide part_of IBA GO_Central GO_REF:0000033 NCBI chr26:28,247,878...28,263,519 JBrowse link
G SNRPE small nuclear ribonucleoprotein polypeptide E part_of IBA GO_Central GO_REF:0000033 NCBI chr38:515,808...521,536
Ensembl chr38:515,860...521,535 		JBrowse link
G SNRPG small nuclear ribonucleoprotein polypeptide G part_of IBA GO_Central GO_REF:0000033 NCBI chr10:68,826,250...68,836,755
Ensembl chr10:68,826,250...68,836,755
Ensembl chr10:68,826,250...68,836,755 		JBrowse link
G SNU13 small nuclear ribonucleoprotein 13 part_of IBA GO_Central GO_REF:0000033 NCBI chr10:23,622,897...23,631,526
Ensembl chr10:23,618,293...23,631,004 		JBrowse link
G WBP4 WW domain binding protein 4 part_of IBA GO_Central GO_REF:0000033 NCBI chr22:9,504,525...9,565,230
Ensembl chr22:9,505,012...9,565,208 		JBrowse link
U2-type precatalytic spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BUD13 BUD13 homolog part_of IEA Ensembl GO_REF:0000107 NCBI chr 5:16,789,297...16,862,933
Ensembl chr 5:16,789,313...16,888,894 		JBrowse link
G CWC22 CWC22 spliceosome associated protein homolog part_of IEA Ensembl GO_REF:0000107 NCBI chr36:23,355,501...23,415,059
Ensembl chr36:23,168,979...23,397,045 		JBrowse link
G CWC27 CWC27 spliceosome associated cyclophilin part_of IEA Ensembl GO_REF:0000107 NCBI chr 2:50,654,977...50,847,055
Ensembl chr 2:50,655,037...50,846,604 		JBrowse link
G DHX16 DEAH-box helicase 16 part_of IEA Ensembl GO_REF:0000107 NCBI chr12:460,669...478,026
Ensembl chr12:460,713...478,001 		JBrowse link
G EFTUD2 elongation factor Tu GTP binding domain containing 2 part_of IEA Ensembl GO_REF:0000107 NCBI chr 9:18,585,918...18,631,743
Ensembl chr 9:18,585,971...18,635,570 		JBrowse link
G IK IK cytokine part_of IEA Ensembl GO_REF:0000107 NCBI chr 2:35,805,631...35,818,205
Ensembl chr 2:35,805,689...35,818,050 		JBrowse link
G LSM2 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated part_of IEA Ensembl GO_REF:0000107 NCBI chr12:1,270,328...1,279,269 JBrowse link
G LSM3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated part_of IEA Ensembl GO_REF:0000107 NCBI chr20:4,328,930...4,342,731
Ensembl chr20:4,329,038...4,342,859 		JBrowse link
G LSM4 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated part_of IEA Ensembl GO_REF:0000107 NCBI chr20:44,707,460...44,720,490
Ensembl chr20:44,707,460...44,720,490 		JBrowse link
G LSM5 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated part_of ISO (PMID:28781166) UniProt PMID:28781166 NCBI chr14:44,857,882...44,860,929
Ensembl chr14:44,857,930...44,860,821 		JBrowse link
G LSM6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated part_of ISO (PMID:28781166) UniProt PMID:28781166 NCBI chr15:44,651,830...44,666,418
Ensembl chr15:44,651,830...44,666,418 		JBrowse link
G LSM7 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated part_of ISO (PMID:28781166) UniProt PMID:28781166 NCBI chr20:56,730,476...56,735,115
Ensembl chr20:56,730,486...56,735,112 		JBrowse link
G LSM8 LSM8 homolog, U6 small nuclear RNA associated part_of ISO (PMID:28781166) UniProt PMID:28781166 NCBI chr14:56,908,344...56,916,512 JBrowse link
G MAGOHB mago homolog B, exon junction complex subunit part_of ISO (PMID:28502770) UniProt PMID:28502770 NCBI chr27:35,125,786...35,133,372 JBrowse link
G MFAP1 microfibril associated protein 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr30:10,545,987...10,559,507
Ensembl chr30:10,546,369...10,559,414 		JBrowse link
G PHF5A PHD finger protein 5A part_of IEA Ensembl GO_REF:0000107 NCBI chr10:23,798,854...23,809,024
Ensembl chr10:23,798,969...23,808,865 		JBrowse link
G PRPF3 pre-mRNA processing factor 3 part_of IEA Ensembl GO_REF:0000107 NCBI chr17:59,552,227...59,577,027
Ensembl chr17:59,552,340...59,577,009 		JBrowse link
G PRPF31 pre-mRNA processing factor 31 part_of IEA Ensembl GO_REF:0000107 NCBI chr 1:103,073,359...103,090,652
Ensembl chr 1:103,073,380...103,090,652 		JBrowse link
G PRPF38A pre-mRNA processing factor 38A part_of IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr15:8,950,621...8,965,205
Ensembl chr15:8,950,805...8,965,085 		JBrowse link
G PRPF4 pre-mRNA splicing tri-snRNP complex factor PRPF4 part_of IEA Ensembl GO_REF:0000107 NCBI chr11:67,641,332...67,659,070
Ensembl chr11:67,641,459...67,657,870 		JBrowse link
G PRPF6 pre-mRNA processing factor 6 part_of IEA Ensembl GO_REF:0000107 NCBI chr24:47,439,210...47,483,531
Ensembl chr24:47,433,130...47,483,522 		JBrowse link
G PRPF8 pre-mRNA processing factor 8 part_of IEA Ensembl GO_REF:0000107 NCBI chr 9:45,797,882...45,827,365
Ensembl chr 9:45,797,959...45,828,071 		JBrowse link
G RBMX2 RNA binding motif protein X-linked 2 part_of IEA Ensembl GO_REF:0000107 NCBI chr  X:101,533,732...101,547,147
Ensembl chr  X:101,533,835...101,544,552 		JBrowse link
G RNF113A ring finger protein 113A part_of ISO (PMID:29360106) UniProt PMID:29360106 NCBI chr  X:91,884,757...91,885,998
Ensembl chr  X:91,884,808...91,885,854 		JBrowse link
G SART1 spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP part_of IEA Ensembl GO_REF:0000107 NCBI chr18:51,297,419...51,313,804
Ensembl chr18:51,297,419...51,313,793 		JBrowse link
G SF3A1 splicing factor 3a subunit 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr26:23,485,551...23,504,242
Ensembl chr26:23,485,797...23,504,346 		JBrowse link
G SF3A2 splicing factor 3a subunit 2 part_of IEA Ensembl GO_REF:0000107 NCBI chr20:56,789,450...56,796,004
Ensembl chr20:56,788,577...56,795,262 		JBrowse link
G SF3A3 splicing factor 3a subunit 3 part_of ISO (PMID:29360106), (PMID:8022796) UniProt PMID:8022796 PMID:29360106 NCBI chr15:4,595,812...4,620,565 JBrowse link
G SF3B1 splicing factor 3b subunit 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr37:6,922,150...6,962,474
Ensembl chr37:6,924,047...6,962,896 		JBrowse link
G SF3B2 splicing factor 3b subunit 2 part_of IEA Ensembl GO_REF:0000107 NCBI chr18:51,197,924...51,212,397
Ensembl chr18:51,197,939...51,212,354 		JBrowse link
G SF3B3 splicing factor 3b subunit 3 part_of IEA Ensembl GO_REF:0000107 NCBI chr 5:76,490,622...76,543,877
Ensembl chr 5:76,490,682...76,543,877 		JBrowse link
G SF3B4 splicing factor 3b subunit 4 part_of IEA Ensembl GO_REF:0000107 NCBI chr17:59,208,989...59,214,643
Ensembl chr17:59,208,990...59,213,991 		JBrowse link
G SF3B5 splicing factor 3b subunit 5 part_of IEA Ensembl GO_REF:0000107 NCBI chr 1:35,558,249...35,558,998
Ensembl chr 1:35,558,599...35,558,859 		JBrowse link
G SMU1 SMU1 DNA replication regulator and spliceosomal factor part_of IEA Ensembl GO_REF:0000107 NCBI chr11:50,172,679...50,195,719
Ensembl chr11:50,174,153...50,195,644 		JBrowse link
G SNIP1 Smad nuclear interacting protein 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr15:4,924,035...4,934,565
Ensembl chr15:4,924,178...4,933,724 		JBrowse link
G SNRNP200 small nuclear ribonucleoprotein U5 subunit 200 part_of ISO (PMID:29361316) UniProt PMID:29361316 NCBI chr17:34,472,638...34,505,332
Ensembl chr17:34,472,767...34,505,333 		JBrowse link
G SNRPA1 small nuclear ribonucleoprotein polypeptide A' part_of ISO (PMID:28781166) UniProt PMID:28781166 NCBI chr 3:39,777,947...39,791,256
Ensembl chr 3:39,777,987...39,790,849 		JBrowse link
G SNRPB small nuclear ribonucleoprotein polypeptides B and B1 part_of IEA Ensembl GO_REF:0000107 NCBI chr24:18,673,975...18,683,315
Ensembl chr24:18,674,039...18,683,229 		JBrowse link
G SNRPB2 small nuclear ribonucleoprotein polypeptide B2 part_of ISO (PMID:28781166) UniProt PMID:28781166 NCBI chr24:6,106,217...6,117,369
Ensembl chr24:6,106,217...6,117,369 		JBrowse link
G SNRPD1 small nuclear ribonucleoprotein D1 polypeptide part_of IEA Ensembl GO_REF:0000107 NCBI chr 7:66,407,313...66,421,193
Ensembl chr 7:66,407,313...66,421,194 		JBrowse link
G SNRPD2 small nuclear ribonucleoprotein D2 polypeptide part_of ISO (PMID:28781166) UniProt PMID:28781166 NCBI chr 1:109,891,253...109,896,712
Ensembl chr 1:109,891,223...109,896,711 		JBrowse link
G SNRPD3 small nuclear ribonucleoprotein D3 polypeptide part_of ISO (PMID:28781166) UniProt PMID:28781166 NCBI chr26:28,247,878...28,263,519 JBrowse link
G SNRPE small nuclear ribonucleoprotein polypeptide E part_of ISO (PMID:28781166) UniProt PMID:28781166 NCBI chr38:515,808...521,536
Ensembl chr38:515,860...521,535 		JBrowse link
G SNRPF small nuclear ribonucleoprotein polypeptide F part_of ISO (PMID:28781166) UniProt PMID:28781166 NCBI chr15:35,691,071...35,698,734 JBrowse link
G SNRPG small nuclear ribonucleoprotein polypeptide G part_of ISO (PMID:28781166) UniProt PMID:28781166 NCBI chr10:68,826,250...68,836,755
Ensembl chr10:68,826,250...68,836,755
Ensembl chr10:68,826,250...68,836,755 		JBrowse link
G SNU13 small nuclear ribonucleoprotein 13 part_of ISO (PMID:28781166) UniProt PMID:28781166 NCBI chr10:23,622,897...23,631,526
Ensembl chr10:23,618,293...23,631,004 		JBrowse link
G SRRM2 serine/arginine repetitive matrix 2 part_of ISO (PMID:29361316) UniProt PMID:29361316 NCBI chr 6:38,291,847...38,310,624
Ensembl chr 6:38,291,842...38,393,924 		JBrowse link
G TXNL4A thioredoxin like 4A part_of IEA Ensembl GO_REF:0000107 NCBI chr 1:722,223...735,253
Ensembl chr 1:722,293...735,258 		JBrowse link
G WBP4 WW domain binding protein 4 part_of IEA Ensembl GO_REF:0000107 NCBI chr22:9,504,525...9,565,230
Ensembl chr22:9,505,012...9,565,208 		JBrowse link
G ZMAT2 zinc finger matrin-type 2 part_of ISO (PMID:28781166) UniProt PMID:28781166 NCBI chr 2:35,851,972...35,860,818
Ensembl chr 2:35,852,109...35,858,065 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 23075
    protein-containing complex 9442
      nuclear protein-containing complex 4368
        spliceosomal complex 221
          precatalytic spliceosome 60
            U12-type precatalytic spliceosome 0
            U2-type precatalytic spliceosome 50
Path 2
Term Annotations click to browse term
  cellular_component 23075
    cellular anatomical structure 22785
      organelle 17404
        membrane-bounded organelle 16138
          intracellular membrane-bounded organelle 15599
            nucleus 11283
              nuclear protein-containing complex 4368
                spliceosomal complex 221
                  precatalytic spliceosome 60
                    U12-type precatalytic spliceosome 0
                    U2-type precatalytic spliceosome 50
paths to the root