SNIP1 (Smad nuclear interacting protein 1) - Rat Genome Database

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Gene: SNIP1 (Smad nuclear interacting protein 1) Canis lupus familiaris
Analyze
Symbol: SNIP1
Name: Smad nuclear interacting protein 1
RGD ID: 12347864
Description: ENCODES a protein that exhibits transcription regulator inhibitor activity (inferred); INVOLVED IN miRNA processing (inferred); mRNA splicing, via spliceosome (inferred); negative regulation of canonical NF-kappaB signal transduction (inferred); ASSOCIATED WITH ARTERIAL DISSECTION (ortholog); benign epilepsy with centrotemporal spikes (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: smad nuclear-interacting protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1154,924,035 - 4,934,565 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl154,924,178 - 4,933,724 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha155,170,972 - 5,181,500 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0155,058,195 - 5,068,724 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl155,058,250 - 5,068,659 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1154,917,372 - 4,927,894 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0154,983,733 - 4,994,245 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0155,000,424 - 5,010,952 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SNIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1154,924,035 - 4,934,565 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl154,924,178 - 4,933,724 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha155,170,972 - 5,181,500 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0155,058,195 - 5,068,724 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl155,058,250 - 5,068,659 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1154,917,372 - 4,927,894 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0154,983,733 - 4,994,245 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0155,000,424 - 5,010,952 (+)NCBIUU_Cfam_GSD_1.0
SNIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38137,534,449 - 37,554,293 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl137,534,449 - 37,554,293 (-)EnsemblGRCh38hg38GRCh38
GRCh37138,000,050 - 38,019,894 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36137,774,729 - 37,792,490 (-)NCBINCBI36Build 36hg18NCBI36
Celera136,280,132 - 36,297,891 (-)NCBICelera
Cytogenetic Map1p34.3NCBI
HuRef136,116,864 - 36,136,791 (-)NCBIHuRef
CHM1_1138,116,178 - 38,136,124 (-)NCBICHM1_1
T2T-CHM13v2.0137,399,180 - 37,419,043 (-)NCBIT2T-CHM13v2.0
Snip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394124,960,465 - 124,967,836 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4124,960,465 - 124,967,835 (+)EnsemblGRCm39 Ensembl
GRCm384125,066,672 - 125,074,043 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4125,066,672 - 125,074,042 (+)EnsemblGRCm38mm10GRCm38
MGSCv374124,743,937 - 124,751,287 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364124,568,997 - 124,576,339 (+)NCBIMGSCv36mm8
Celera4123,387,926 - 123,395,275 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map457.99NCBI
Snip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85142,613,028 - 142,620,502 (+)NCBIGRCr8
mRatBN7.25137,328,371 - 137,335,846 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5137,328,371 - 137,335,845 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5140,032,513 - 140,039,986 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05141,802,531 - 141,810,004 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05141,809,697 - 141,817,170 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01519,275,273 - 19,282,753 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5143,063,099 - 143,070,884 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05146,831,845 - 146,839,471 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45144,409,078 - 144,416,987 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15144,419,070 - 144,426,979 (+)NCBI
Celera5135,846,577 - 135,854,025 (+)NCBICelera
Cytogenetic Map5q36NCBI
Snip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545215,353,182 - 15,365,459 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545215,352,080 - 15,365,545 (-)NCBIChiLan1.0ChiLan1.0
SNIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21189,284,872 - 189,302,648 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11188,413,926 - 188,431,693 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0136,807,488 - 36,827,347 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1138,156,936 - 38,176,803 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl138,155,375 - 38,176,803 (-)Ensemblpanpan1.1panPan2
Snip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505853,935,987 - 53,953,447 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647419,760,766 - 19,778,265 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647419,760,653 - 19,778,224 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl693,597,059 - 93,612,150 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1693,597,050 - 93,612,169 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SNIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12095,315,272 - 95,327,402 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2095,315,297 - 95,336,101 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603321,479,232 - 21,496,625 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476420,280,055 - 20,292,916 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SNIP1
70 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000005285   ⟹   ENSCAFP00000004890
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl154,924,178 - 4,933,724 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845054493   ⟹   ENSCAFP00845042831
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl155,058,250 - 5,068,659 (+)Ensembl
RefSeq Acc Id: XM_014119585   ⟹   XP_013975060
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1154,924,035 - 4,934,565 (+)NCBI
Dog10K_Boxer_Tasha155,170,972 - 5,181,500 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022427817   ⟹   XP_022283525
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1154,924,533 - 4,934,565 (+)NCBI
Dog10K_Boxer_Tasha155,171,474 - 5,181,500 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038495507   ⟹   XP_038351435
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1154,917,372 - 4,927,894 (+)NCBI
RefSeq Acc Id: XM_038495508   ⟹   XP_038351436
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1154,917,873 - 4,927,894 (+)NCBI
RefSeq Acc Id: XM_038557857   ⟹   XP_038413785
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0155,000,424 - 5,010,952 (+)NCBI
RefSeq Acc Id: XM_038557858   ⟹   XP_038413786
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0155,000,926 - 5,010,952 (+)NCBI
RefSeq Acc Id: XM_038621729   ⟹   XP_038477657
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0154,983,733 - 4,994,245 (+)NCBI
RefSeq Acc Id: XM_038621730   ⟹   XP_038477658
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0154,984,232 - 4,994,245 (+)NCBI
RefSeq Acc Id: XM_038687502   ⟹   XP_038543430
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0155,058,195 - 5,068,724 (+)NCBI
RefSeq Acc Id: XM_038687503   ⟹   XP_038543431
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0155,058,695 - 5,068,724 (+)NCBI
RefSeq Acc Id: XP_013975060   ⟸   XM_014119585
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RLX1 (UniProtKB/TrEMBL),   A0A8I3QBA4 (UniProtKB/TrEMBL),   A0A8C0K652 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022283525   ⟸   XM_022427817
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSCAFP00000004890   ⟸   ENSCAFT00000005285
RefSeq Acc Id: XP_038351435   ⟸   XM_038495507
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038351436   ⟸   XM_038495508
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038477657   ⟸   XM_038621729
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038477658   ⟸   XM_038621730
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038543430   ⟸   XM_038687502
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RLX1 (UniProtKB/TrEMBL),   A0A8I3QBA4 (UniProtKB/TrEMBL),   A0A8C0K652 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038543431   ⟸   XM_038687503
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038413785   ⟸   XM_038557857
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K652 (UniProtKB/TrEMBL),   A0A8C0RLX1 (UniProtKB/TrEMBL),   A0A8I3QBA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038413786   ⟸   XM_038557858
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCAFP00845042831   ⟸   ENSCAFT00845054493
Protein Domains
FHA

Promoters
RGD ID:13685864
Promoter ID:EPDNEW_C3931
Type:multiple initiation site
Name:SNIP1_1
Description:Smad nuclear interacting protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1154,924,066 - 4,924,126EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003301 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030016820 UniProtKB/TrEMBL
  ENSCAFG00040005700 UniProtKB/TrEMBL
  ENSCAFG00845030697 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000005285.6 UniProtKB/TrEMBL
  ENSCAFT00030031020.1 UniProtKB/TrEMBL
  ENSCAFT00040010685.1 UniProtKB/TrEMBL
  ENSCAFT00845054493 ENTREZGENE
  ENSCAFT00845054493.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.200.20 UniProtKB/TrEMBL
InterPro Cell_Proc_Reg/RNA_Proc UniProtKB/TrEMBL
  FHA_dom UniProtKB/TrEMBL
  SMAD_FHA_dom_sf UniProtKB/TrEMBL
KEGG Report cfa:106557470 UniProtKB/TrEMBL
NCBI Gene SNIP1 ENTREZGENE
PANTHER KANADAPTIN-RELATED UniProtKB/TrEMBL
  NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 UniProtKB/TrEMBL
Pfam FHA UniProtKB/TrEMBL
PROSITE FHA_DOMAIN UniProtKB/TrEMBL
SMART FHA UniProtKB/TrEMBL
Superfamily-SCOP SSF49879 UniProtKB/TrEMBL
UniProt A0A8C0K652 ENTREZGENE
  A0A8C0RLX1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QBA4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:46602 ENTREZGENE