IK (IK cytokine) - Rat Genome Database

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Gene: IK (IK cytokine) Canis lupus familiaris
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Symbol: IK
Name: IK cytokine
RGD ID: 12113526
Description: ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN mitotic cell cycle (ortholog); ASSOCIATED WITH autosomal dominant non-syndromic intellectual disability 31 (ortholog); autosomal dominant nonsyndromic deafness 1 (ortholog); familial adenomatous polyposis 1 (ortholog); FOUND IN mitotic spindle pole (ortholog); nuclear chromosome (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: IK cytokine, down-regulator of HLA II; protein Red
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,805,631 - 35,818,205 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,805,689 - 35,818,050 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,844,638 - 32,857,193 (+)NCBI
ROS_Cfam_1.0236,261,280 - 36,273,815 (+)NCBI
UMICH_Zoey_3.1233,313,649 - 33,326,167 (+)NCBI
UNSW_CanFamBas_1.0234,181,413 - 34,193,941 (+)NCBI
UU_Cfam_GSD_1.0234,934,115 - 34,946,646 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
IK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,805,631 - 35,818,205 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,805,689 - 35,818,050 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,844,638 - 32,857,193 (+)NCBI
ROS_Cfam_1.0236,261,280 - 36,273,815 (+)NCBI
UMICH_Zoey_3.1233,313,649 - 33,326,167 (+)NCBI
UNSW_CanFamBas_1.0234,181,413 - 34,193,941 (+)NCBI
UU_Cfam_GSD_1.0234,934,115 - 34,946,646 (+)NCBI
IK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5140,647,058 - 140,662,480 (+)EnsemblGRCh38hg38GRCh38
GRCh385140,647,818 - 140,662,480 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375140,027,414 - 140,042,065 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365140,007,568 - 140,022,249 (+)NCBINCBI36hg18NCBI36
Build 345140,007,567 - 140,022,098NCBI
Celera5136,104,129 - 136,118,812 (+)NCBI
Cytogenetic Map5q31.3ENTREZGENE
HuRef5135,172,621 - 135,187,305 (+)ENTREZGENEHuRef
CHM1_15139,460,619 - 139,475,314 (+)NCBICHM1_1
Ik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391836,877,709 - 36,890,692 (+)NCBIGRCm39mm39
GRCm39 Ensembl1836,877,709 - 36,890,692 (+)Ensembl
GRCm381836,744,656 - 36,757,639 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1836,744,656 - 36,757,639 (+)EnsemblGRCm38mm10GRCm38
MGSCv371836,904,310 - 36,917,293 (+)NCBIGRCm37mm9NCBIm37
MGSCv361836,870,690 - 36,883,609 (+)NCBImm8
Celera1837,196,721 - 37,209,702 (+)NCBICelera
Cytogenetic Map18B2NCBI
Ik
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21828,358,004 - 28,372,809 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1828,357,977 - 28,378,832 (+)Ensembl
Rnor_6.01829,587,901 - 29,602,705 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,587,901 - 29,608,338 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01829,291,708 - 29,306,512 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41829,444,004 - 29,458,808 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11829,470,649 - 29,485,454 (+)NCBI
Celera1828,078,557 - 28,093,361 (+)NCBICelera
Cytogenetic Map18p11NCBI
Ik
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541839,695 - 52,862 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541839,695 - 52,862 (-)NCBIChiLan1.0ChiLan1.0
IK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15142,129,130 - 142,143,393 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5142,129,130 - 142,143,393 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05136,012,381 - 136,027,099 (+)NCBIMhudiblu_PPA_v0panPan3
Ik
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213152,010,239 - 152,022,723 (-)NCBI
SpeTri2.0NW_0049365319,589,035 - 9,601,266 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2142,361,155 - 142,378,745 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12142,361,134 - 142,376,335 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22148,305,095 - 148,320,513 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12343,280,876 - 43,295,844 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2343,280,981 - 43,297,843 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603434,588,676 - 34,603,675 (-)NCBIVero_WHO_p1.0
Ik
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474333,400,359 - 33,413,993 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000009474   ⟹   ENSCAFP00000008794
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl235,805,689 - 35,818,050 (+)Ensembl
RefSeq Acc Id: XM_005617285   ⟹   XP_005617342
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1235,805,631 - 35,818,205 (+)NCBI
Dog10K_Boxer_Tasha232,844,638 - 32,857,193 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038469582   ⟹   XP_038325510
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1233,313,649 - 33,326,167 (+)NCBI
RefSeq Acc Id: XM_038530347   ⟹   XP_038386275
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0234,934,115 - 34,946,646 (+)NCBI
RefSeq Acc Id: XM_038594598   ⟹   XP_038450526
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0234,181,413 - 34,193,941 (+)NCBI
RefSeq Acc Id: XM_038658639   ⟹   XP_038514567
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0236,261,280 - 36,273,815 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_005617342   ⟸   XM_005617285
- UniProtKB: F1PL89 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000008794   ⟸   ENSCAFT00000009474
RefSeq Acc Id: XP_038325510   ⟸   XM_038469582
RefSeq Acc Id: XP_038450526   ⟸   XM_038594598
RefSeq Acc Id: XP_038514567   ⟸   XM_038658639
RefSeq Acc Id: XP_038386275   ⟸   XM_038530347

Promoters
RGD ID:13682447
Promoter ID:EPDNEW_C517
Type:initiation region
Name:IK_1
Description:IK cytokine
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1235,805,748 - 35,805,808EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005869 Ensembl
NCBI Gene IK ENTREZGENE
UniProt F1PL89 ENTREZGENE
VGNC ID VGNC:54958 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-09-26 IK  IK cytokine    IK cytokine, down-regulator of HLA II  Symbol and/or name change 5135510 APPROVED