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ONTOLOGY REPORT - ANNOTATIONS

Term:NAD+ nucleotidase, cyclic ADP-ribose generating
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Accession:GO:0061809 term browser browse the term
Definition:Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose, in a two steps reaction: first an ADP-ribosyl cyclase reaction, followed by a cyclic ADP-ribose hydrolase reaction.
Synonyms:exact_synonym: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
 narrow_synonym: NAD hydrolase;   NAD(+) nucleosidase;   NADase;   nicotinamide adenine dinucleotide nucleosidase
 xref: EC:3.2.2.6;   MetaCyc:NADNUCLEOSID-RXN;   RHEA:16301


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NAD+ nucleotidase, cyclic ADP-ribose generating term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Art2b ADP-ribosyltransferase 2b enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 1:155,956,601...155,974,252
Ensembl chr 1:155,956,603...155,974,253 		JBrowse link
G Bst1 bone marrow stromal cell antigen 1 enables IEA
ISO		 GO_REF:0000003
(PMID:11866528), (PMID:7805847)
GO_REF:0000002		 UniProt
RGD
InterPro		 PMID:7805847 PMID:11866528 GO_REF:0000002 GO_REF:0000003 NCBI chr14:67,253,706...67,270,203
Ensembl chr14:67,252,998...67,270,180 		JBrowse link
G Cd38 CD38 molecule enables IDA
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:11733184 GO_REF:0000002, RGD:1299847 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Il1rap interleukin 1 receptor accessory protein enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530 		JBrowse link
G Il1rapl1 interleukin 1 receptor accessory protein-like 1 enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr  X:51,371,969...52,876,726
Ensembl chr  X:51,378,215...52,876,772 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il1rl2 interleukin 1 receptor-like 2 enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667 		JBrowse link
G Sarm1 sterile alpha and TIR motif containing 1 enables ISO (PMID:28334607), (PMID:31128467) RGD PMID:28334607 PMID:31128467 NCBI chr10:63,369,456...63,393,016
Ensembl chr10:63,369,456...63,392,822 		JBrowse link
G Tlr4 toll-like receptor 4 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20729
    catalytic activity 6109
      hydrolase activity 2595
        hydrolase activity, acting on glycosyl bonds 129
          hydrolase activity, hydrolyzing N-glycosyl compounds 33
            NAD+ nucleotidase, cyclic ADP-ribose generating 10
paths to the root