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ONTOLOGY REPORT - ANNOTATIONS


Term:SUMO ligase activity
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Accession:GO:0061665 term browser browse the term
Definition:Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S = X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate.
Synonyms:related_synonym: E3
 xref: Reactome:R-HSA-9834809 "SUMOylation of PKR";   Reactome:R-HSA-9842868 "TRIM28 in TRIM28:KRAB-ZFP:retroelement chromatin autoSUMOylates with SUMO2"



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SUMO ligase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbx4 chromobox 4 enables ISO
IBA
(PMID:27068747)
GO_REF:0000033
RGD
GO_Central
PMID:27068747 GO_REF:0000033 NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706
JBrowse link
G Egr2 early growth response 2 enables ISO (PMID:21836637) RGD PMID:21836637 NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899
JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 enables ISO
IBA
(PMID:18579533), (PMID:27068747), (PMID:36050397)
(PMID:16600910), (PMID:22539995)
GO_REF:0000033
RGD
GO_Central
PMID:16600910 PMID:18579533 PMID:22539995 PMID:27068747 PMID:36050397 GO_REF:0000033 NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905
JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 enables ISO
IEA
IBA
(PMID:20408817)
(PMID:18579533)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:18579533 PMID:20408817 GO_REF:0000033 GO_REF:0000107 NCBI chr18:72,883,008...72,989,486
Ensembl chr18:70,607,665...70,710,033
JBrowse link
G Pias3 protein inhibitor of activated STAT, 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:186,921,384...186,930,292
Ensembl chr 2:184,232,571...184,241,480
JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 enables ISO
IBA
(PMID:18579533), (PMID:32832608), (PMID:34048572), (PMID:35013556)
(PMID:19955185)
GO_REF:0000033
RGD
GO_Central
PMID:18579533 PMID:19955185 PMID:32832608 PMID:34048572 PMID:35013556 GO_REF:0000033 NCBI chr 7:8,546,312...8,559,838
Ensembl chr 7:8,546,312...8,559,808
JBrowse link
G Ranbp2 RAN binding protein 2 enables ISO (PMID:17264123) RGD PMID:17264123 NCBI chr20:26,442,156...26,493,481
Ensembl chr20:26,442,217...26,493,481
JBrowse link
G Zfp451 zinc finger protein 451 enables ISO
IBA
(PMID:26524494)
GO_REF:0000033
RGD
GO_Central
PMID:26524494 GO_REF:0000033 NCBI chr 9:43,481,395...43,546,103
Ensembl chr 9:35,985,443...36,040,652
JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:1,033,983...1,239,425
Ensembl chr16:1,027,325...1,232,597
JBrowse link
G Zmiz2 zinc finger, MIZ-type containing 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:85,465,323...85,481,860
Ensembl chr14:81,251,417...81,267,936
JBrowse link
SUMO-ubiquitin ligase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trim60 tripartite motif containing 60 enables ISO (PMID:33184450) RGD PMID:33184450 NCBI chr16:24,722,770...24,724,188 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      catalytic activity, acting on a protein 2509
        ubiquitin-like protein transferase activity 455
          SUMO transferase activity 27
            SUMO ligase activity 12
              SUMO-ubiquitin ligase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      transferase activity 2444
        acyltransferase activity 722
          aminoacyltransferase activity 471
            ubiquitin-like protein transferase activity 455
              ubiquitin-like protein ligase activity 353
                SUMO ligase activity 12
                  SUMO-ubiquitin ligase activity 1
paths to the root