ONTOLOGY REPORT - ANNOTATIONS
Term: SUMO ligase activity
Accession: GO:0061665
browse the term
Definition: Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S = X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate.
Synonyms: related_synonym: E3
xref: Reactome:R-HSA-9834809 "SUMOylation of PKR"
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Cbx4
chromobox 4
enables
ISO IBA
(PMID:27068747) GO_REF:0000033
RGD GO_Central
PMID:27068747
GO_REF:0000033
NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706
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Egr2
early growth response 2
enables
ISO
(MGI:5508720|PMID:21836637)
RGD
PMID:21836637
MGI:5508720
NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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ENSRNOG00000070780
enables
IEA
GO_REF:0000118
TreeGrafter
GO_REF:0000118
Ensembl chr 3:76,228,298...76,230,622
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Nsmce2
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
enables
IEA IBA
GO_REF:0000118 GO_REF:0000033
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899
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Pias1
protein inhibitor of activated STAT, 1
enables
ISO IBA
(MGI:3620509|PMID:16600910) GO_REF:0000033 (PMID:18579533), (PMID:27068747), (PMID:36050397)
RGD GO_Central
PMID:16600910 PMID:18579533 PMID:27068747 PMID:36050397
GO_REF:0000033 MGI:3620509
NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905
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Pias2
protein inhibitor of activated STAT, 2
enables
ISO IEA IBA
(PMID:20408817) (PMID:18579533) GO_REF:0000107 GO_REF:0000118 GO_REF:0000033
RGD Ensembl TreeGrafter GO_Central
PMID:18579533 PMID:20408817
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr18:70,608,034...70,714,295
Ensembl chr18:70,607,665...70,710,033
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Pias3
protein inhibitor of activated STAT, 3
enables
IEA IBA
GO_REF:0000118 GO_REF:0000033
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 2:184,232,546...184,241,455
Ensembl chr 2:184,232,571...184,241,480
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Pias4
protein inhibitor of activated STAT, 4
enables
ISO IBA
(MGI:4887534|PMID:19955185) (PMID:18579533), (PMID:32832608), (PMID:34048572), (PMID:35013556) GO_REF:0000033
RGD GO_Central
PMID:18579533 PMID:19955185 PMID:32832608 PMID:34048572 PMID:35013556
GO_REF:0000033 MGI:4887534
NCBI chr 7:8,546,312...8,559,838
Ensembl chr 7:8,546,312...8,559,808
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Ranbp2
RAN binding protein 2
enables
ISO
(PMID:17264123)
RGD
PMID:17264123
NCBI chr20:26,442,156...26,493,481
Ensembl chr20:26,442,217...26,493,481
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Zfp451
zinc finger protein 451
enables
ISO IBA
(PMID:26524494) GO_REF:0000033
RGD GO_Central
PMID:26524494
GO_REF:0000033
NCBI chr 9:35,985,441...36,040,991
Ensembl chr 9:35,985,443...36,040,652
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Zmiz1
zinc finger, MIZ-type containing 1
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr16:1,027,083...1,232,616
Ensembl chr16:1,027,325...1,232,597
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Zmiz2
zinc finger, MIZ-type containing 2
enables
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr14:81,251,391...81,267,936
Ensembl chr14:81,251,417...81,267,936
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Trim60
tripartite motif containing 60
enables
ISO
(PMID:33184450)
RGD
PMID:33184450
NCBI chr16:24,722,770...24,724,188
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all