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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of nuclear division
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Accession:GO:0051784 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
Synonyms:exact_synonym: down regulation of nuclear division;   downregulation of nuclear division
 narrow_synonym: inhibition of nuclear division

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deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) UniProt PMID:19010891 NCBI chrNW_004624740:27,174,450...27,523,366
Ensembl chrNW_004624740:27,174,354...27,523,492 		JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624754:16,044,275...16,047,500
Ensembl chrNW_004624754:16,045,331...16,047,497 		JBrowse link
G Prap1 proline rich acidic protein 1 involved_in ISO (PMID:24374861) UniProt PMID:24374861 NCBI chrNW_004624737:13,346,621...13,350,428
Ensembl chrNW_004624737:13,343,674...13,351,284 		JBrowse link
meiotic recombination checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hormad1 HORMA domain containing 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:4868505|PMID:21079677), (MGI:5009722|PMID:21478856)
(PMID:22530760)		 UniProt
MGI		 PMID:21079677 PMID:21478856 PMID:22530760 MGI:4868505 MGI:5009722 NCBI chrNW_004624772:18,379,154...18,403,456
Ensembl chrNW_004624772:18,379,745...18,403,745 		JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624759:19,994,660...20,001,545
Ensembl chrNW_004624759:19,994,696...20,001,541 		JBrowse link
G Trip13 thyroid hormone receptor interactor 13 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624751:439,195...459,033
Ensembl chrNW_004624751:439,119...459,080 		JBrowse link
mitotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO (PMID:17227893) MGI PMID:17227893 NCBI chrNW_004624743:30,517,034...30,635,740
Ensembl chrNW_004624743:30,546,323...30,635,737 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:11943150) UniProt PMID:11943150 NCBI chrNW_004624784:2,933,172...3,080,131
Ensembl chrNW_004624784:2,937,499...3,078,216 		JBrowse link
G Birc5 baculoviral IAP repeat containing 5 involved_in ISO (PMID:12805209) UniProt PMID:12805209 NCBI chrNW_004624801:7,727,084...7,735,946
Ensembl chrNW_004624801:7,727,093...7,735,940 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624749:1,584,289...1,639,334
Ensembl chrNW_004624749:1,584,186...1,639,770 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624804:7,477,046...7,533,322
Ensembl chrNW_004624804:7,492,799...7,533,408 		JBrowse link
G Bub3 BUB3 mitotic checkpoint protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624737:23,847,449...23,860,382
Ensembl chrNW_004624737:23,847,785...23,860,603 		JBrowse link
G Cenpe centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chrNW_004624830:4,930,533...4,986,437
Ensembl chrNW_004624830:4,930,555...4,986,076 		JBrowse link
G Haspin histone H3 associated protein kinase involved_in ISO (PMID:23071153) UniProt PMID:23071153 NCBI chrNW_004624786:6,371,639...6,374,517
Ensembl chrNW_004624786:6,371,874...6,374,195 		JBrowse link
G Ik IK cytokine involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624743:33,400,359...33,413,993
Ensembl chrNW_004624743:33,400,459...33,413,993 		JBrowse link
G Klhl22 kelch like family member 22 involved_in ISO (PMID:23455478) UniProt PMID:23455478 NCBI chrNW_004624945:409,093...446,619
Ensembl chrNW_004624945:408,999...441,975 		JBrowse link
G Kntc1 kinetochore associated 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624747:22,667,872...22,758,411
Ensembl chrNW_004624747:22,669,297...22,758,226 		JBrowse link
G LOC101715712 inactive serine/threonine-protein kinase TEX14 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624871:578,323...679,120 JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624740:27,174,450...27,523,366
Ensembl chrNW_004624740:27,174,354...27,523,492 		JBrowse link
G Plk1 polo like kinase 1 involved_in ISO (PMID:23455478) UniProt PMID:23455478 NCBI chrNW_004624782:8,811,593...8,823,060
Ensembl chrNW_004624782:8,811,616...8,826,749 		JBrowse link
G Psmg2 proteasome assembly chaperone 2 acts_upstream_of_or_within ISO (PMID:12147697) MGI PMID:12147697 NCBI chrNW_004624770:19,787,876...19,802,623
Ensembl chrNW_004624770:19,788,057...19,802,422 		JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624733:20,326,565...20,350,937
Ensembl chrNW_004624733:20,326,893...20,350,923 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO (PMID:20133940) UniProt PMID:20133940 NCBI chrNW_004624814:7,249,379...7,306,239
Ensembl chrNW_004624814:7,249,278...7,306,235 		JBrowse link
G Trip13 thyroid hormone receptor interactor 13 involved_in ISO (PMID:28553959) UniProt PMID:28553959 NCBI chrNW_004624751:439,195...459,033
Ensembl chrNW_004624751:439,119...459,080 		JBrowse link
G Ttk TTK protein kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624819:6,631,697...6,682,181 JBrowse link
G Znf207 zinc finger protein 207 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624875:434,770...463,977
Ensembl chrNW_004624875:434,087...453,932 		JBrowse link
G Zw10 zw10 kinetochore protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624784:9,221,123...9,255,294
Ensembl chrNW_004624784:9,221,128...9,255,284 		JBrowse link
G Zwilch zwilch kinetochore protein involved_in IEA UniProt
TreeGrafter		 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004624781:6,168,482...6,209,581
Ensembl chrNW_004624781:6,171,114...6,209,380 		JBrowse link
G Zwint ZW10 interacting kinetochore protein involved_in ISO (PMID:15485811) HGNC-UCL PMID:15485811 NCBI chrNW_004624791:7,528,452...7,534,182
Ensembl chrNW_004624791:7,528,426...7,534,553 		JBrowse link
negative regulation of meiotic nuclear division term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmrt1 doublesex and mab-3 related transcription factor 1 involved_in ISO (MGI:4839662|PMID:20951351) UniProt PMID:20951351 MGI:4839662 NCBI chrNW_004624736:5,525,417...5,641,612
Ensembl chrNW_004624736:5,525,408...5,645,636 		JBrowse link
G Fbxo5 F-box protein 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15526037) InterPro
TreeGrafter
MGI		 PMID:15526037 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624785:5,248,434...5,260,623
Ensembl chrNW_004624785:5,247,731...5,260,736 		JBrowse link
G Lif LIF interleukin 6 family cytokine acts_upstream_of_or_within ISO (PMID:11203703) MGI PMID:11203703 NCBI chrNW_004624747:6,558,872...6,565,207
Ensembl chrNW_004624747:6,558,817...6,565,281 		JBrowse link
G Nanos2 nanos C2HC-type zinc finger 2 involved_in ISO (MGI:3776712|PMID:18281459) UniProt PMID:18281459 MGI:3776712 NCBI chrNW_004624832:7,309,334...7,310,645 JBrowse link
G Osm oncostatin M acts_upstream_of_or_within ISO (PMID:11203703) MGI PMID:11203703 NCBI chrNW_004624747:6,580,717...6,584,695 JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha ISO RGD PMID:12088872 RGD:633705 NCBI chrNW_004624870:3,552,608...3,575,461
Ensembl chrNW_004624870:3,552,745...3,574,880 		JBrowse link
G Rgs22 regulator of G protein signaling 22 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624763:6,922,059...7,059,827
Ensembl chrNW_004624763:6,923,087...7,037,726
Ensembl chrNW_004624763:6,923,087...7,037,726 		JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 acts_upstream_of_or_within ISO (PMID:15526037) MGI PMID:15526037 NCBI chrNW_004624785:12,450,686...12,839,563
Ensembl chrNW_004624785:12,657,845...12,839,569 		JBrowse link
negative regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:11988738), (PMID:16921029) UniProt PMID:11988738 PMID:16921029 NCBI chrNW_004624785:5,248,434...5,260,623
Ensembl chrNW_004624785:5,247,731...5,260,736 		JBrowse link
G Rad21 RAD21 cohesin complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624763:15,131,106...15,157,512
Ensembl chrNW_004624763:15,131,005...15,158,155 		JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624750:11,697,919...11,725,421
Ensembl chrNW_004624750:11,710,218...11,724,529 		JBrowse link
negative regulation of mitotic nuclear division term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO (PMID:17244894) UniProt PMID:17244894 NCBI chrNW_004624731:15,262,480...15,269,196
Ensembl chrNW_004624731:15,263,274...15,269,743 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO (PMID:17244894) UniProt PMID:17244894 NCBI chrNW_004624741:23,658,214...23,743,227
Ensembl chrNW_004624741:23,658,004...23,737,742 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624927:1,609,404...1,643,409
Ensembl chrNW_004624927:1,610,878...1,643,409 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO (PMID:18455718) MGI PMID:18455718 NCBI chrNW_004624737:25,052,698...25,158,346
Ensembl chrNW_004624737:25,052,606...25,158,529 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:18455718) MGI PMID:18455718 NCBI chrNW_004624755:25,633,690...25,647,361
Ensembl chrNW_004624755:25,635,165...25,646,932 		JBrowse link
G Mtbp MDM2 binding protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21274008) Ensembl
MGI		 PMID:21274008 GO_REF:0000107 NCBI chrNW_004624763:18,228,820...18,299,706
Ensembl chrNW_004624763:18,228,252...18,299,925 		JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624730:73,414,124...73,421,161
Ensembl chrNW_004624730:73,414,798...73,419,261 		JBrowse link
G Tom1l1 target of myb1 like 1 membrane trafficking protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624795:10,206,059...10,248,395
Ensembl chrNW_004624795:10,205,533...10,247,379 		JBrowse link
G Tom1l2 target of myb1 like 2 membrane trafficking protein involved_in ISO (PMID:16479011) UniProt PMID:16479011 NCBI chrNW_004624849:3,466,572...3,594,397
Ensembl chrNW_004624849:3,466,520...3,594,738 		JBrowse link
negative regulation of mitotic spindle assembly checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ska1 spindle and kinetochore associated complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624778:13,948,567...13,968,643
Ensembl chrNW_004624778:13,953,390...13,968,683 		JBrowse link
G Ska3 spindle and kinetochore associated complex subunit 3 involved_in ISO (PMID:19646878) UniProt PMID:19646878 NCBI chrNW_004624776:16,412,683...16,450,784
Ensembl chrNW_004624776:16,413,048...16,445,892 		JBrowse link
positive regulation of meiosis I spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Knl1 kinetochore scaffold 1 involved_in ISO (MGI:7356173|PMID:35167144) UniProt PMID:35167144 MGI:7356173 NCBI chrNW_004624804:7,884,580...7,952,567
Ensembl chrNW_004624804:7,889,689...7,952,384 		JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 involved_in ISO (PMID:19229290) UniProt PMID:19229290 NCBI chrNW_004624788:10,593,647...10,624,755
Ensembl chrNW_004624788:10,593,940...10,625,052 		JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624738:689,835...718,549
Ensembl chrNW_004624738:696,080...718,240 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624740:27,174,450...27,523,366
Ensembl chrNW_004624740:27,174,354...27,523,492 		JBrowse link
G Ndc80 NDC80 kinetochore complex component involved_in ISO (PMID:25743205) UniProt PMID:25743205 NCBI chrNW_004624770:12,937,887...12,974,352
Ensembl chrNW_004624770:12,939,763...12,974,162 		JBrowse link
G Pcid2 PCI domain containing 2 involved_in ISO (MGI:4839685|PMID:20870947)
(PMID:20870947)		 UniProt PMID:20870947 MGI:4839685 NCBI chrNW_004624793:722,743...744,824
Ensembl chrNW_004624793:722,762...744,743 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO (PMID:18981471), (PMID:19273613) UniProt PMID:18981471 PMID:19273613 NCBI chrNW_004624814:7,249,379...7,306,239
Ensembl chrNW_004624814:7,249,278...7,306,235 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO (PMID:23108668) UniProt PMID:23108668 NCBI chrNW_004624734:1,216,641...1,223,860
Ensembl chrNW_004624734:1,217,549...1,223,280 		JBrowse link
regulation of meiosis I spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zwint ZW10 interacting kinetochore protein involved_in ISO (MGI:6215447|PMID:26486467) UniProt PMID:26486467 MGI:6215447 NCBI chrNW_004624791:7,528,452...7,534,182
Ensembl chrNW_004624791:7,528,426...7,534,553 		JBrowse link
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc15 anaphase promoting complex subunit 15 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624817:4,863,426...4,866,452
Ensembl chrNW_004624817:4,864,670...4,866,452 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624760:14,736,273...14,930,168
Ensembl chrNW_004624760:14,736,104...14,930,119 		JBrowse link
G Knl1 kinetochore scaffold 1 involved_in ISO (PMID:19893618) UniProt PMID:19893618 NCBI chrNW_004624804:7,884,580...7,952,567
Ensembl chrNW_004624804:7,889,689...7,952,384 		JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 acts_upstream_of_or_within ISO (PMID:17724024) MGI PMID:17724024 NCBI chrNW_004624782:9,974,415...10,043,475
Ensembl chrNW_004624782:9,979,433...10,043,475 		JBrowse link
G Prp4k pre-mRNA processing factor kinase PRP4K involved_in ISO (PMID:17998396) UniProt PMID:17998396 NCBI chrNW_004624756:21,038,438...21,082,607 JBrowse link
G Usp44 ubiquitin specific peptidase 44 involved_in ISO (MGI:5448515|PMID:21853124) UniProt PMID:21853124 MGI:5448515 NCBI chrNW_004624750:11,697,919...11,725,421
Ensembl chrNW_004624750:11,710,218...11,724,529 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15225
    negative regulation of biological process 5102
      negative regulation of cellular process 4723
        negative regulation of cellular component organization 745
          negative regulation of organelle organization 360
            negative regulation of nuclear division 58
              negative regulation of meiotic nuclear division + 13
              negative regulation of mitotic nuclear division + 49
Path 2
Term Annotations click to browse term
  biological_process 15225
    cellular process 14346
      cellular component organization or biogenesis 6258
        cellular component organization 6068
          organelle organization 3392
            organelle fission 482
              nuclear division 429
                regulation of nuclear division 136
                  negative regulation of nuclear division 58
                    negative regulation of meiotic nuclear division + 13
                    negative regulation of mitotic nuclear division + 49
paths to the root