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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of melanin biosynthetic process
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Accession:GO:0048021 term browser browse the term
Definition:Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
Synonyms:exact_synonym: regulation of melanin anabolism;   regulation of melanin biosynthesis;   regulation of melanin formation;   regulation of melanin synthesis

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regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:6,296,975...6,318,266
Ensembl chrNW_004624786:6,298,243...6,317,743 		JBrowse link
G Mfsd12 major facilitator superfamily domain containing 12 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624828:6,255,889...6,268,697
Ensembl chrNW_004624828:6,259,618...6,268,272 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO (PMID:16037214) MGI PMID:16037214 NCBI chrNW_004624777:18,540,006...18,619,881
Ensembl chrNW_004624777:18,546,799...18,619,947 		JBrowse link
negative regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO (PMID:29025994) CACAO PMID:29025994 NCBI chrNW_004624828:6,255,889...6,268,697
Ensembl chrNW_004624828:6,259,618...6,268,272 		JBrowse link
G Opn3 opsin 3 involved_in ISO (PMID:31097585) UniProt PMID:31097585 NCBI chrNW_004624771:11,943,894...11,991,477
Ensembl chrNW_004624771:11,943,914...11,991,411 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISO (PMID:16272156) UniProt PMID:16272156 NCBI chrNW_004624848:3,968,845...4,184,740
Ensembl chrNW_004624848:3,968,362...4,182,885 		JBrowse link
G Slc24a5 solute carrier family 24 member 5 acts_upstream_of_or_within ISO (PMID:18166528) MGI PMID:18166528 NCBI chrNW_004624731:11,552,865...11,573,987
Ensembl chrNW_004624731:11,552,969...11,574,044 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:23569434) CACAO PMID:23569434 NCBI chrNW_004624822:1,824,378...1,843,599
Ensembl chrNW_004624822:1,825,238...1,841,288 		JBrowse link
positive regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:21291857) UniProt PMID:21291857 NCBI chrNW_004624822:31,175...74,252
Ensembl chrNW_004624822:33,880...74,308 		JBrowse link
G Asip agouti signaling protein involved_in ISO (PMID:21949658) CACAO PMID:21949658 NCBI chrNW_004624842:5,079,499...5,084,933
Ensembl chrNW_004624842:5,079,499...5,084,933 		JBrowse link
G Atp7a ATPase copper transporting alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624836:2,804,349...3,058,125
Ensembl chrNW_004624836:2,808,681...2,993,452 		JBrowse link
G Cdh3 cadherin 3 involved_in ISO (PMID:23334344) UniProt PMID:23334344 NCBI chrNW_004624746:17,616,296...17,659,021
Ensembl chrNW_004624746:17,616,940...17,658,548 		JBrowse link
G Opn3 opsin 3 involved_in ISO (PMID:28842328) UniProt PMID:28842328 NCBI chrNW_004624771:11,943,894...11,991,477
Ensembl chrNW_004624771:11,943,914...11,991,411 		JBrowse link
G Pmel premelanosome protein involved_in ISO (PMID:21949658) CACAO PMID:21949658 NCBI chrNW_004624802:12,073,932...12,092,885
Ensembl chrNW_004624802:12,083,090...12,092,767 		JBrowse link
G Rab38 RAB38, member RAS oncogene family ISO RGD PMID:17043139 RGD:152025192 NCBI chrNW_004624845:1,908,410...1,983,897
Ensembl chrNW_004624845:1,906,671...1,984,029 		JBrowse link
G Tyrp1 tyrosinase related protein 1 involved_in ISO (PMID:21996312)
(PMID:21949658)		 CACAO PMID:21949658 PMID:21996312 NCBI chrNW_004624736:17,011,092...17,028,689
Ensembl chrNW_004624736:17,011,115...17,029,322 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17637
    cellular process 17219
      metabolic process 11013
        phenol-containing compound metabolic process 126
          melanin metabolic process 25
            melanin biosynthetic process 23
              regulation of melanin biosynthetic process 14
                negative regulation of melanin biosynthetic process 5
                positive regulation of melanin biosynthetic process 8
Path 2
Term Annotations click to browse term
  biological_process 17637
    biological regulation 11843
      regulation of biological process 11485
        regulation of cellular process 11159
          regulation of metabolic process 5978
            regulation of secondary metabolic process 14
              regulation of secondary metabolite biosynthetic process 14
                regulation of melanin biosynthetic process 14
                  negative regulation of melanin biosynthetic process 5
                  positive regulation of melanin biosynthetic process 8
paths to the root