Mfsd12 (major facilitator superfamily domain containing 12) - Rat Genome Database

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Gene: Mfsd12 (major facilitator superfamily domain containing 12) Heterocephalus glaber
Analyze
Symbol: Mfsd12
Name: major facilitator superfamily domain containing 12
RGD ID: 18918117
Description: ENCODES a protein that exhibits cysteine transmembrane transporter activity (ortholog); INVOLVED IN cysteine transmembrane transport (ortholog); hair follicle development (ortholog); negative regulation of melanin biosynthetic process (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN late endosome (ortholog); lysosome (ortholog); melanosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: major facilitator superfamily domain-containing protein 12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248286,259,618 - 6,268,272 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248286,255,889 - 6,268,697 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
late endosome  (ISO)
lysosome  (ISO)
melanosome  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Mfsd12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248286,259,618 - 6,268,272 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248286,255,889 - 6,268,697 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MFSD12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38193,538,275 - 3,557,586 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl193,538,261 - 3,574,290 (-)EnsemblGRCh38hg38GRCh38
GRCh37193,544,197 - 3,557,584 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,489,263 - 3,508,571 (-)NCBINCBI36Build 36hg18NCBI36
Build 34193,495,197 - 3,508,561NCBI
Celera193,475,073 - 3,494,380 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef193,303,815 - 3,323,043 (-)NCBIHuRef
CHM1_1193,537,933 - 3,557,234 (-)NCBICHM1_1
T2T-CHM13v2.0193,516,446 - 3,535,742 (-)NCBIT2T-CHM13v2.0
Mfsd12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391081,193,325 - 81,202,059 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1081,193,325 - 81,202,059 (+)EnsemblGRCm39 Ensembl
GRCm381081,357,491 - 81,366,225 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1081,357,491 - 81,366,225 (+)EnsemblGRCm38mm10GRCm38
MGSCv371080,820,315 - 80,826,780 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361080,820,236 - 80,828,967 (+)NCBIMGSCv36mm8
Celera1082,378,603 - 82,385,068 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Mfsd12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr878,998,050 - 9,004,724 (-)NCBIGRCr8
mRatBN7.278,345,171 - 8,354,050 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,347,314 - 8,353,988 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx711,232,889 - 11,239,559 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,108,376 - 13,115,046 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0710,976,036 - 10,982,709 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,214,832 - 11,223,713 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,216,975 - 11,223,649 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,383,866 - 11,390,540 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,831,853 - 9,838,324 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.179,829,711 - 9,837,769 (-)NCBI
Celera76,536,377 - 6,543,051 (-)NCBICelera
Cytogenetic Map7q11NCBI
Mfsd12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554955,506,154 - 5,516,142 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554955,505,528 - 5,516,330 (-)NCBIChiLan1.0ChiLan1.0
MFSD12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2207,936,086 - 7,954,989 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,173,528 - 7,186,956 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0192,570,068 - 2,583,505 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1193,519,886 - 3,548,934 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,520,399 - 3,532,767 (-)Ensemblpanpan1.1panPan2
MFSD12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,855,102 - 55,863,606 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,858,687 - 55,862,181 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2055,579,634 - 55,588,060 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02056,514,447 - 56,522,856 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2056,514,215 - 56,524,326 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12055,570,115 - 55,578,534 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02056,053,492 - 56,061,939 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02056,252,252 - 56,260,682 (+)NCBIUU_Cfam_GSD_1.0
Mfsd12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,815,659 - 215,823,018 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,011,506 - 2,019,125 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,011,838 - 2,019,119 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MFSD12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl275,107,529 - 75,120,705 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1275,098,531 - 75,120,795 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2275,765,114 - 75,775,975 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MFSD12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.163,307,855 - 3,322,966 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl63,304,960 - 3,322,896 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660815,171,004 - 5,184,456 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000020608   ⟹   ENSHGLP00000020406
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248286,259,618 - 6,268,272 (-)Ensembl
RefSeq Acc Id: XM_004865835   ⟹   XP_004865892
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248286,257,414 - 6,268,697 (-)NCBI
RefSeq Acc Id: XM_004865837   ⟹   XP_004865894
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248286,259,522 - 6,268,692 (-)NCBI
RefSeq Acc Id: XM_021244857   ⟹   XP_021100516
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248286,255,889 - 6,268,697 (-)NCBI
RefSeq Acc Id: XM_021244858   ⟹   XP_021100517
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248286,255,944 - 6,268,695 (-)NCBI
RefSeq Acc Id: XM_021244859   ⟹   XP_021100518
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248286,255,949 - 6,268,695 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004865892 (Get FASTA)   NCBI Sequence Viewer  
  XP_004865894 (Get FASTA)   NCBI Sequence Viewer  
  XP_021100516 (Get FASTA)   NCBI Sequence Viewer  
  XP_021100517 (Get FASTA)   NCBI Sequence Viewer  
  XP_021100518 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000020406
Reference Protein Sequences
RefSeq Acc Id: XP_021100516   ⟸   XM_021244857
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021100517   ⟸   XM_021244858
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021100518   ⟸   XM_021244859
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004865892   ⟸   XM_004865835
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004865894   ⟸   XM_004865837
- Peptide Label: isoform X4
RefSeq Acc Id: ENSHGLP00000020406   ⟸   ENSHGLT00000020608


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014588 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000020608 ENTREZGENE
NCBI Gene Mfsd12 ENTREZGENE