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ONTOLOGY REPORT - ANNOTATIONS


Term:phenol-containing compound metabolic process
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Accession:GO:0018958 term browser browse the term
Definition:The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.
Comment:Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds.
Synonyms:exact_synonym: carbolic acid metabolic process;   carbolic acid metabolism;   hydroxybenzene metabolic process;   hydroxybenzene metabolism;   phenol-containing compound metabolism
 xref: UM-BBD_pathwayID:phe


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phenol-containing compound metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP bisphenol A RGD PMID:18191889 RGD:4831838 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP bisphenol A RGD PMID:18191889 RGD:4831838 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 IEP gossypol RGD PMID:19429456 RGD:4890959 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP gossypol RGD PMID:19429456 RGD:4890959
G Star steroidogenic acute regulatory protein IEP bisphenol A RGD PMID:18191889 RGD:4831838 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 ISO (PMID:9463486) RGD PMID:9463486 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
JBrowse link
4-nitrophenol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO (PMID:9348445) RGD PMID:9348445 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 IDA RGD PMID:11181495 RGD:2301074 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
catechol-containing compound metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase ISO MGI:MGI:4830700 (MGI:MGI:4830461|PMID:19930170) RGD PMID:19930170 MGI:MGI:4830461 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
catecholamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:17194738 RGD:5131263 NCBI chr 4:85,286,371...85,329,374
Ensembl chr 4:85,286,372...85,329,362
JBrowse link
G Ddc dopa decarboxylase TAS
IEA
GO_REF:0000043 UniProt PMID:12047348 GO_REF:0000043, RGD:727571 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Hdc histidine decarboxylase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Th tyrosine hydroxylase IDA RGD PMID:20025246 RGD:4139888 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
catecholamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:11559542), (PMID:15645182), (PMID:21846718)
UniProt
RGD
PMID:11559542, PMID:15645182, PMID:21846718, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing ISO
IBA
ISS
(MGI:MGI:3799635|PMID:18794526)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:18794526, PMID:21873635 GO_REF:0000024, MGI:MGI:3799635, RGD:13792537 NCBI chr 1:166,985,468...166,989,681
Ensembl chr 1:166,986,013...166,988,062
JBrowse link
G Maoa monoamine oxidase A NAS RGD PMID:12388421 RGD:629546 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO MGI:MGI:1856098 (MGI:MGI:54307|PMID:17511) RGD PMID:17511 MGI:MGI:54307 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Dbh dopamine beta-hydroxylase IC RGD PMID:11521740 RGD:1625401 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Ddc dopa decarboxylase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Mtpn myotrophin IEP RGD PMID:12051753 RGD:625450 NCBI chr 4:63,012,009...63,039,422
Ensembl chr 4:63,012,011...63,039,422
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 IDA RGD PMID:6959650 RGD:2301075 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult1d1 sulfotransferase family 1D, member 1 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr14:22,107,418...22,126,011
Ensembl chr14:22,091,777...22,126,021
JBrowse link
dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:20097214 RGD:6903884 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:20097214 RGD:6903884 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit IEP RGD PMID:12438507 RGD:704388 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:19818757 RGD:5143981 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Dao D-amino-acid oxidase IEA
ISO
GO_REF:0000107
(PMID:17303072)
Ensembl
RGD
PMID:17303072 GO_REF:0000107 NCBI chr12:48,353,691...48,373,647
Ensembl chr12:48,354,196...48,365,784
JBrowse link
G Ddc dopa decarboxylase IDA
IEA
GO_REF:0000041 UniProt PMID:12703659 GO_REF:0000041, RGD:4139893 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO (PMID:16338639) RGD PMID:16338639 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gpr37 G protein-coupled receptor 37 ISO MGI:MGI:3027995 (MGI:MGI:3046856|PMID:15218106) RGD PMID:15218106 MGI:MGI:3046856 NCBI chr 4:51,822,163...51,844,228
Ensembl chr 4:51,822,153...51,844,331
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 IEA
ISO
GO_REF:0000107
MGI:MGI:2429971 (MGI:MGI:1203924|PMID:9608532), (MGI:MGI:3767764|PMID:16782508)
Ensembl
RGD
PMID:9608532, PMID:16782508 GO_REF:0000107, MGI:MGI:1203924, MGI:MGI:3767764 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO MGI:MGI:2386303 (MGI:MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:MGI:2386819 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Snca synuclein alpha ISO MGI:MGI:1888382 (MGI:MGI:1352916|PMID:10707987) RGD PMID:10707987 MGI:MGI:1352916 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO
ISS
(MGI:MGI:3622848|PMID:16257223)
GO_REF:0000024
RGD
UniProt
PMID:16257223 GO_REF:0000024, MGI:MGI:3622848 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Th tyrosine hydroxylase ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
dopamine biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Th tyrosine hydroxylase IDA
IBA
ISO
IMP
PMID:21873635
MGI:MGI:1860450 (MGI:MGI:2386819|PMID:9520487), (MGI:MGI:72094|PMID:7715703), (MGI:MGI:77787|PMID:7592982)
PMID:11943812
RGD PMID:7592982, PMID:7715703, PMID:9520487, PMID:2427363, PMID:21873635, PMID:11943812, PMID:19584816 MGI:MGI:2386819, MGI:MGI:72094, MGI:MGI:77787, RGD:1580046, RGD:13792537, RGD:5129111, RGD:5130972 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
dopamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase ISO (MGI:MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:MGI:2386819 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Dbh dopamine beta-hydroxylase IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
MGI:MGI:1857556 (MGI:MGI:1332340|PMID:10051631), (MGI:MGI:5787847|PMID:27148966), (MGI:MGI:72180|PMID:7715704)
(PMID:3443096), (PMID:7961964)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:3443096, PMID:7715704, PMID:7961964, PMID:10051631, PMID:27148966, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1332340, MGI:MGI:5787847, MGI:MGI:72180, RGD:13792537 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Maoa monoamine oxidase A ISO
IEA
(MGI:MGI:2386819|PMID:9520487)
GO_REF:0000107
RGD
Ensembl
PMID:9520487 GO_REF:0000107, MGI:MGI:2386819 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:22,124,498...22,206,565
Ensembl chr 1:22,124,495...22,206,505
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO MGI:MGI:2386303 (MGI:MGI:2386819|PMID:9520487) RGD PMID:9520487 MGI:MGI:2386819 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO MGI:MGI:1856098|MGI:MGI:1856466 (MGI:MGI:50550|PMID:1752214), (MGI:MGI:65000|PMID:8174230) RGD PMID:1752214, PMID:8174230 MGI:MGI:50550, MGI:MGI:65000, MGI:MGI:71923 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Comt catechol-O-methyltransferase ISO
IBA
MGI:MGI:2178542|MGI:MGI:4830700 (MGI:MGI:4830461|PMID:19930170), (MGI:MGI:5510279|PMID:23863468)
PMID:21873635
RGD PMID:19930170, PMID:23863468, PMID:21873635 MGI:MGI:4830461, MGI:MGI:5510279, RGD:13792537 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:10945868 RGD:1599723 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Ddc dopa decarboxylase TAS RGD PMID:7567987 RGD:727686 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Drd2 dopamine receptor D2 ISO (MGI:MGI:68905|PMID:7925842) RGD PMID:7925842 MGI:MGI:68905 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO
IEA
MGI:MGI:1928285 (MGI:MGI:2384280|PMID:11160454)
GO_REF:0000107
RGD
Ensembl
PMID:11160454 GO_REF:0000107, MGI:MGI:2384280 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO MGI:MGI:1857299 (MGI:MGI:1321418|PMID:9886073), (MGI:MGI:65825|PMID:7509865), (MGI:MGI:65928|PMID:1432691) RGD PMID:1432691, PMID:7509865, PMID:9886073 MGI:MGI:1321418, MGI:MGI:65825, MGI:MGI:65928 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:166,985,468...166,989,681
Ensembl chr 1:166,986,013...166,988,062
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 ISO MGI:MGI:3527173 (MGI:MGI:6150107|PMID:28327638) RGD PMID:28327638 MGI:MGI:6150107 NCBI chr 2:46,372,488...46,476,162
Ensembl chr 2:46,372,518...46,476,203
JBrowse link
G Npr1 natriuretic peptide receptor 1 IMP RGD PMID:15544851 RGD:1580153 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 ISO MGI:MGI:2429971 (MGI:MGI:3529728|PMID:12385813) RGD PMID:12385813 MGI:MGI:3529728 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase NOT ISO MGI:MGI:2678247 (MGI:MGI:2675710|PMID:12915482)
MGI:MGI:3055212 (MGI:MGI:3525458|PMID:15684050)
RGD PMID:12915482, PMID:15684050 MGI:MGI:2675710, MGI:MGI:3525458 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Snca synuclein alpha ISO MGI:MGI:1889011 (MGI:MGI:3057254|PMID:15465911) RGD PMID:15465911 MGI:MGI:3057254 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sncaip synuclein, alpha interacting protein ISO
ISS
(PMID:14506261)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:14506261 GO_REF:0000024 NCBI chr18:47,739,284...47,877,679
Ensembl chr18:47,739,140...47,877,676
JBrowse link
G Sncb synuclein, beta ISO
IEA
MGI:MGI:1277151 (MGI:MGI:3057254|PMID:15465911)
GO_REF:0000107
RGD
Ensembl
PMID:15465911 GO_REF:0000107, MGI:MGI:3057254 NCBI chr17:10,384,472...10,392,776
Ensembl chr17:10,384,511...10,392,843
JBrowse link
G Spr sepiapterin reductase ISO MGI:MGI:3757641 (MGI:MGI:3722569|PMID:16532389) RGD PMID:16532389 MGI:MGI:3722569 NCBI chr 4:116,912,343...116,916,073
Ensembl chr 4:116,912,351...116,916,236
JBrowse link
epinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnmt phenylethanolamine-N-methyltransferase TAS
IEA
IDA
IC
GO_REF:0000041 UniProt PMID:11514309, PMID:7914070, PMID:7503429 GO_REF:0000041, RGD:628457, RGD:4139902, RGD:4139901 NCBI chr10:86,340,893...86,342,501
Ensembl chr10:86,340,940...86,342,858
JBrowse link
G Th tyrosine hydroxylase ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
epinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO MGI:MGI:1856098|MGI:MGI:1856466 (MGI:MGI:50550|PMID:1752214) RGD PMID:1752214 MGI:MGI:50550, MGI:MGI:71923 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
homogentisate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fah fumarylacetoacetate hydrolase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:146,713,663...146,736,339
Ensembl chr 1:146,713,676...146,736,261
JBrowse link
melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asip agouti signaling protein ISO MGI:MGI:1855937 (MGI:MGI:76308|PMID:7665913) RGD PMID:7665913 MGI:MGI:76308 NCBI chr 3:150,492,010...150,579,870
Ensembl chr 3:150,574,473...150,579,870
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 ISO
ISS
(MGI:MGI:4412464|PMID:11434569)
GO_REF:0000024
RGD
UniProt
PMID:11434569 GO_REF:0000024, MGI:MGI:4412464 NCBI chr  X:72,128,996...72,133,692
Ensembl chr  X:72,128,994...72,133,692
JBrowse link
G Dct dopachrome tautomerase ISO MGI:MGI:1856379 (MGI:MGI:76308|PMID:7665913) RGD PMID:7665913 MGI:MGI:76308 NCBI chr15:103,208,174...103,245,033
Ensembl chr15:103,208,258...103,244,494
JBrowse link
G Ddt D-dopachrome tautomerase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:13,827,153...13,829,624
Ensembl chr20:13,827,132...13,831,588
JBrowse link
G Mc1r melanocortin 1 receptor ISO MGI:MGI:1856028 (MGI:MGI:76308|PMID:7665913) RGD PMID:7665913 MGI:MGI:76308 NCBI chr19:56,215,420...56,219,987 JBrowse link
G Myo5a myosin VA ISO
IEA
MGI:MGI:1856004 (MGI:MGI:76308|PMID:7665913)
GO_REF:0000107
RGD
Ensembl
PMID:7665913 GO_REF:0000107, MGI:MGI:76308 NCBI chr 8:82,038,966...82,156,507
Ensembl chr 8:82,037,977...82,156,617
JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein ISO MGI:MGI:1856114 (MGI:MGI:1202196|PMID:9548375), (MGI:MGI:76308|PMID:7665913) RGD PMID:7665913, PMID:9548375 MGI:MGI:1202196, MGI:MGI:76308 NCBI chr 1:114,661,970...114,987,433
Ensembl chr 1:114,679,537...114,987,433
JBrowse link
G Pmel premelanosome protein ISO MGI:MGI:1857040 (MGI:MGI:76308|PMID:7665913) RGD PMID:7665913 MGI:MGI:76308 NCBI chr 7:3,133,347...3,143,827
Ensembl chr 7:3,133,506...3,143,911
JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 ISO
IEA
(PMID:8126111)
GO_REF:0000107
RGD
Ensembl
PMID:8126111 GO_REF:0000107 NCBI chr 8:103,503,982...103,554,905
Ensembl chr 8:103,503,985...103,554,468
JBrowse link
G Tyr tyrosinase ISO
IBA
(PMID:8126111)
PMID:21873635
MGI:MGI:1855976|MGI:MGI:1855978 (MGI:MGI:1202196|PMID:9548375), (MGI:MGI:76308|PMID:7665913)
RGD PMID:7665913, PMID:8126111, PMID:9548375, PMID:21873635 MGI:MGI:1202196, MGI:MGI:76308, RGD:13792537 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Tyrp1 tyrosinase-related protein 1 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:98,387,291...98,406,083
Ensembl chr 5:98,387,291...98,406,083
JBrowse link
melanin biosynthetic process from tyrosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dct dopachrome tautomerase ISO (MGI:MGI:3690794|PMID:2169885) RGD PMID:2169885 MGI:MGI:3690794 NCBI chr15:103,208,174...103,245,033
Ensembl chr15:103,208,258...103,244,494
JBrowse link
melanin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator ISO
IEA
MGI:MGI:2156165 (MGI:MGI:2154874|PMID:11709185)
GO_REF:0000107
RGD
Ensembl
PMID:11709185 GO_REF:0000107, MGI:MGI:2154874 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Myo5a myosin VA ISO MGI:MGI:1856004 (MGI:MGI:1202196|PMID:9548375) RGD PMID:9548375 MGI:MGI:1202196 NCBI chr 8:82,038,966...82,156,507
Ensembl chr 8:82,037,977...82,156,617
JBrowse link
G Tyrp1 tyrosinase-related protein 1 ISO MGI:MGI:1855960 (MGI:MGI:1202196|PMID:9548375) RGD PMID:9548375 MGI:MGI:1202196 NCBI chr 5:98,387,291...98,406,083
Ensembl chr 5:98,387,291...98,406,083
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO MGI:MGI:2136645 (MGI:MGI:5429122|PMID:22627278) RGD PMID:22627278 MGI:MGI:5429122 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
negative regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO MGI:MGI:1856098 (MGI:MGI:54307|PMID:17511) RGD PMID:17511 MGI:MGI:54307 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
negative regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase IMP RGD PMID:15190105 RGD:2289786 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP RGD PMID:17018023 RGD:1625003 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Itgam integrin subunit alpha M ISO (MGI:MGI:3814938|PMID:18981141) RGD PMID:18981141 MGI:MGI:3814938 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Snca synuclein alpha IMP PMID:11943812 BHF-UCL PMID:11943812 RGD:5129111 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
negative regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd12 major facilitator superfamily domain containing 12 ISO (MGI:MGI:5912387|PMID:29025994) RGD PMID:29025994 MGI:MGI:5912387 NCBI chr 7:11,214,832...11,223,713
Ensembl chr 7:11,216,975...11,223,649
JBrowse link
G Opn3 opsin 3 ISO
IEA
(PMID:31097585)
GO_REF:0000107
RGD
Ensembl
PMID:31097585 GO_REF:0000107 NCBI chr13:93,716,481...93,746,994
Ensembl chr13:93,716,481...93,746,994
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 ISO
ISS
(MGI:MGI:5499726|PMID:16272156)
GO_REF:0000024
RGD
UniProt
PMID:16272156 GO_REF:0000024, MGI:MGI:5499726 NCBI chr 2:177,836,191...178,057,378
Ensembl chr 2:177,836,202...178,057,157
JBrowse link
G Slc24a5 solute carrier family 24 member 5 ISO (MGI:MGI:3775882|PMID:18166528) RGD PMID:18166528 MGI:MGI:3775882 NCBI chr 3:117,335,212...117,354,480
Ensembl chr 3:117,335,212...117,354,480
JBrowse link
G Wnt5a Wnt family member 5A ISO
IEA
(MGI:MGI:5619434|PMID:23569434)
GO_REF:0000107
RGD
Ensembl
PMID:23569434 GO_REF:0000107, MGI:MGI:5619434 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO MGI:MGI:1856097|MGI:MGI:1856098 (MGI:MGI:53801|PMID:4405722), (MGI:MGI:53940|PMID:4858102) RGD PMID:4405722, PMID:4858102 MGI:MGI:53801, MGI:MGI:53940 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Dbh dopamine beta-hydroxylase TAS
IBA
ISO
ISS
IEA
IMP
PMID:21873635
MGI:MGI:1857556 (MGI:MGI:1203930|PMID:9603211), (MGI:MGI:1332340|PMID:10051631), (MGI:MGI:5787847|PMID:27148966), (MGI:MGI:72180|PMID:7715704)
GO_REF:0000024
(PMID:27148966)
GO_REF:0000041
RGD
UniProt
PMID:7715704, PMID:9603211, PMID:10051631, PMID:27148966, PMID:11914591, PMID:21873635, PMID:10573542 GO_REF:0000024, GO_REF:0000041, MGI:MGI:1203930, MGI:MGI:1332340, MGI:MGI:5787847, MGI:MGI:72180, RGD:727567, RGD:13792537, RGD:1625403 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Gata3 GATA binding protein 3 ISO
ISS
MGI:MGI:2153826 (MGI:MGI:1859081|PMID:10835639)
GO_REF:0000024
RGD
UniProt
PMID:10835639 GO_REF:0000024, MGI:MGI:1859081 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Insm1 INSM transcriptional repressor 1 ISO (MGI:MGI:3772428|PMID:18094025) RGD PMID:18094025 MGI:MGI:3772428 NCBI chr 3:140,427,961...140,430,467 JBrowse link
G Kl Klotho IMP RGD PMID:20086041 RGD:10403068 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:22,124,498...22,206,565
Ensembl chr 1:22,124,495...22,206,505
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
JBrowse link
G Th tyrosine hydroxylase ISO (PMID:12457228) RGD PMID:12457228 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
norepinephrine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B IDA RGD PMID:10424772 RGD:8548769 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Atp7a ATPase copper transporting alpha ISO MGI:MGI:1856102|MGI:MGI:1856466 (MGI:MGI:53851|PMID:4147174) RGD PMID:4147174 MGI:MGI:53851, MGI:MGI:71923 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Epas1 endothelial PAS domain protein 1 ISO
IEA
MGI:MGI:1861921 (MGI:MGI:1313089|PMID:9808618)
GO_REF:0000107
RGD
Ensembl
PMID:9808618 GO_REF:0000107, MGI:MGI:1313089 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Ly6e lymphocyte antigen 6 family member E ISO MGI:MGI:2429638 (MGI:MGI:2157257|PMID:11784869) RGD PMID:11784869 MGI:MGI:2157257 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IDA RGD PMID:3945626 RGD:5130757 NCBI chr10:86,340,893...86,342,501
Ensembl chr10:86,340,940...86,342,858
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO MGI:MGI:3050230 (MGI:MGI:3047192|PMID:15249681) RGD PMID:15249681 MGI:MGI:3047192 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Rnf180 ring finger protein 180 ISO
IBA
(MGI:MGI:5505713|PMID:23926250)
PMID:21873635
RGD PMID:23926250, PMID:21873635 MGI:MGI:5505713, RGD:13792537 NCBI chr 2:35,718,100...35,892,578
Ensembl chr 2:35,718,889...35,870,578
JBrowse link
G Rtl4 retrotransposon Gag like 4 ISO MGI:MGI:5789261 (MGI:MGI:5749620|PMID:26402067) RGD PMID:26402067 MGI:MGI:5749620 NCBI chr  X:115,908,999...116,402,406
Ensembl chr  X:116,399,611...116,400,516
JBrowse link
G Spr sepiapterin reductase ISO MGI:MGI:3757641 (MGI:MGI:3722569|PMID:16532389) RGD PMID:16532389 MGI:MGI:3722569 NCBI chr 4:116,912,343...116,916,073
Ensembl chr 4:116,912,351...116,916,236
JBrowse link
octopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:22,124,498...22,206,565
Ensembl chr 1:22,124,495...22,206,505
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
JBrowse link
octopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbh dopamine beta-hydroxylase IMP RGD PMID:11521740 RGD:1625401 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
positive regulation of dopamine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 IMP RGD PMID:19457096 RGD:5128877 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Park7 Parkinsonism associated deglycase ISO
IEA
ISS
(PMID:19703902)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
ParkinsonsUK-UCL
PMID:19703902 GO_REF:0000024, GO_REF:0000107 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Vps35 VPS35 retromer complex component ISO (MGI:MGI:5694519|PMID:26203154) RGD PMID:26203154 MGI:MGI:5694519 NCBI chr19:27,464,937...27,500,636
Ensembl chr19:27,464,937...27,500,636
JBrowse link
positive regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:11239920 RGD:10047061 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Gpr37 G protein-coupled receptor 37 ISO MGI:MGI:3027995 (MGI:MGI:3046856|PMID:15218106) RGD PMID:15218106 MGI:MGI:3046856 NCBI chr 4:51,822,163...51,844,228
Ensembl chr 4:51,822,153...51,844,331
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO (PMID:8643611) RGD PMID:8643611 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Maob monoamine oxidase B IMP RGD PMID:12175458 RGD:2316765 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Npy neuropeptide Y IDA RGD PMID:19579268 RGD:10448966 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
positive regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 ISO (PMID:21291857) RGD PMID:21291857 NCBI chr16:2,560,103...2,602,035
Ensembl chr16:2,563,520...2,602,103
JBrowse link
G Asip agouti signaling protein ISO
IBA
UniProtKB:P07147|UniProtKB:Q60696 (MGI:MGI:5294257|PMID:21949658)
PMID:21873635
RGD PMID:21949658, PMID:21873635 MGI:MGI:5294257, RGD:13792537 NCBI chr 3:150,492,010...150,579,870
Ensembl chr 3:150,574,473...150,579,870
JBrowse link
G Cdh3 cadherin 3 ISO (PMID:23334344) RGD PMID:23334344 NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 ISS
ISO
GO_REF:0000024
(PMID:21291857)
UniProt
RGD
PMID:21291857 GO_REF:0000024 NCBI chr19:24,786,604...24,798,231
Ensembl chr19:24,786,628...24,798,233
JBrowse link
G Opn3 opsin 3 ISO
IEA
(PMID:28842328)
GO_REF:0000107
RGD
Ensembl
PMID:28842328 GO_REF:0000107 NCBI chr13:93,716,481...93,746,994
Ensembl chr13:93,716,481...93,746,994
JBrowse link
G Pmel premelanosome protein ISO (MGI:MGI:5294257|PMID:21949658) RGD PMID:21949658 MGI:MGI:5294257 NCBI chr 7:3,133,347...3,143,827
Ensembl chr 7:3,133,506...3,143,911
JBrowse link
G Tyrp1 tyrosinase-related protein 1 ISO (PMID:21996312)
UniProtKB:Q03288|UniProtKB:Q60696 (MGI:MGI:5294257|PMID:21949658)
RGD PMID:21949658, PMID:21996312 MGI:MGI:5294257 NCBI chr 5:98,387,291...98,406,083
Ensembl chr 5:98,387,291...98,406,083
JBrowse link
positive regulation of thyroid hormone generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 ISS
ISO
GO_REF:0000024
(PMID:19248180), (PMID:19723756)
UniProt
RGD
PMID:19248180, PMID:19723756 GO_REF:0000024 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Hpn hepsin ISO
ISS
(MGI:MGI:3719967|PMID:17620368)
GO_REF:0000024
RGD
UniProt
PMID:17620368 GO_REF:0000024, MGI:MGI:3719967 NCBI chr 1:89,534,112...89,549,575
Ensembl chr 1:89,534,106...89,543,967
JBrowse link
G Pax8 paired box 8 ISO
ISS
(PMID:15356023)
GO_REF:0000024
(MGI:MGI:3691903|PMID:12586753)
RGD
UniProt
PMID:12586753, PMID:15356023 GO_REF:0000024, MGI:MGI:3691903 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Slco1c1 solute carrier organic anion transporter family, member 1c1 ISO
IEA
(PMID:18566113)
GO_REF:0000107
RGD
Ensembl
PMID:18566113 GO_REF:0000107 NCBI chr 4:175,729,709...175,776,749
Ensembl chr 4:175,729,726...175,776,808
JBrowse link
positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 ISO
IEA
(MGI:MGI:4413411|PMID:19008477)
GO_REF:0000107
RGD
Ensembl
PMID:19008477 GO_REF:0000107, MGI:MGI:4413411 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546
JBrowse link
regulation of catecholamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vhl von Hippel-Lindau tumor suppressor IMP RGD PMID:11912140 RGD:619592 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
regulation of dopamine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO MGI:MGI:1926253 (MGI:MGI:3618656|PMID:11282258) RGD PMID:11282258 MGI:MGI:3618656 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Drd1 dopamine receptor D1 ISO
IEA
MGI:MGI:1857158 (MGI:MGI:2136539|PMID:11438590)
GO_REF:0000107
RGD
Ensembl
PMID:11438590 GO_REF:0000107, MGI:MGI:2136539 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd4 dopamine receptor D4 ISO
IEA
MGI:MGI:2178631 (MGI:MGI:1097029|PMID:9323127)
GO_REF:0000107
RGD
Ensembl
PMID:9323127 GO_REF:0000107, MGI:MGI:1097029 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO
ISS
(MGI:MGI:1927024|PMID:11080193)
GO_REF:0000024
RGD
UniProt
PMID:11080193 GO_REF:0000024, MGI:MGI:1927024 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 ISO
IEA
(MGI:MGI:2671567|PMID:12915123)
GO_REF:0000107
RGD
Ensembl
PMID:12915123 GO_REF:0000107, MGI:MGI:2671567 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Pde1b phosphodiesterase 1B ISO MGI:MGI:3604470 (MGI:MGI:3769297|PMID:17559891) RGD PMID:17559891 MGI:MGI:3769297 NCBI chr 7:145,117,951...145,147,711
Ensembl chr 7:145,117,951...145,145,376
JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing ISO MGI:MGI:5006973 (MGI:MGI:5466578|PMID:22214848) RGD PMID:22214848 MGI:MGI:5466578 NCBI chr 9:81,566,074...81,634,531
Ensembl chr 9:81,566,074...81,634,534
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO (PMID:22314364) RGD PMID:22314364 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO MGI:MGI:2386303 (MGI:MGI:2386819|PMID:9520487), (MGI:MGI:894559|PMID:9247269) RGD PMID:9247269, PMID:9520487 MGI:MGI:2386819, MGI:MGI:894559 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:8574643 RGD:2305963 NCBI chr 2:240,021,152...240,118,971
Ensembl chr 2:240,021,152...240,118,971
JBrowse link
regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a11 solute carrier family 7 member 11 ISO MGI:MGI:1857061 (MGI:MGI:3588610|PMID:16037214) RGD PMID:16037214 MGI:MGI:3588610 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
regulation of thyroid hormone generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Duoxa1 dual oxidase maturation factor 1 ISO MGI:MGI:1914061 (MGI:MGI:5544584|PMID:22301785) RGD PMID:22301785 MGI:MGI:5544584 NCBI chr 3:114,241,057...114,251,720
Ensembl chr 3:114,241,057...114,251,647
JBrowse link
G Duoxa2 dual oxidase maturation factor 2 ISO MGI:MGI:2384861 (MGI:MGI:5544584|PMID:22301785) RGD PMID:22301785 MGI:MGI:5544584 NCBI chr 3:114,236,718...114,240,086
Ensembl chr 3:114,236,718...114,240,086
JBrowse link
serotonin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddc dopa decarboxylase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:10027744, PMID:21873635 RGD:5129182, RGD:13792537 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Tph2 tryptophan hydroxylase 2 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 7:58,042,279...58,149,220
Ensembl chr 7:58,042,281...58,149,061
JBrowse link
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IDA RGD PMID:23098818 RGD:11353778 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Tph1 tryptophan hydroxylase 1 TAS RGD PMID:12153488 RGD:625621 NCBI chr 1:102,669,868...102,699,442
Ensembl chr 1:102,669,868...102,699,442
JBrowse link
serotonin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 ISO MGI:MGI:1857092 (MGI:MGI:68065|PMID:2765934) RGD PMID:2765934 MGI:MGI:68065 NCBI chr 4:145,704,779...145,948,997
Ensembl chr 4:145,703,046...146,016,325
JBrowse link
G Atp7a ATPase copper transporting alpha ISO MGI:MGI:1856098 (MGI:MGI:65000|PMID:8174230) RGD PMID:8174230 MGI:MGI:65000 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Btbd9 BTB domain containing 9 ISO MGI:MGI:4127237 (MGI:MGI:5436392|PMID:22678064) RGD PMID:22678064 MGI:MGI:5436392 NCBI chr20:8,899,286...9,253,936
Ensembl chr20:8,901,931...9,249,820
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO
IEA
MGI:MGI:1928285 (MGI:MGI:2384280|PMID:11160454)
GO_REF:0000107
RGD
Ensembl
PMID:11160454 GO_REF:0000107, MGI:MGI:2384280 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO
ISS
(MGI:MGI:1927024|PMID:11080193)
GO_REF:0000024
RGD
UniProt
PMID:11080193 GO_REF:0000024, MGI:MGI:1927024 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Maoa monoamine oxidase A IDA
IMP
Y402A, Y407A, Y410A had an impact on the properties of the protein while Y402F, Y410F had little effect; the residues are near the C406 FAD binding site RGD PMID:11754741, PMID:11754741, PMID:11263670 RGD:1600709, RGD:1600709, RGD:1600713 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Pde1b phosphodiesterase 1B ISO MGI:MGI:3604470 (MGI:MGI:3769297|PMID:17559891) RGD PMID:17559891 MGI:MGI:3769297 NCBI chr 7:145,117,951...145,147,711
Ensembl chr 7:145,117,951...145,145,376
JBrowse link
G Rnf180 ring finger protein 180 ISO
IBA
(MGI:MGI:5505713|PMID:23926250)
PMID:21873635
RGD PMID:23926250, PMID:21873635 MGI:MGI:5505713, RGD:13792537 NCBI chr 2:35,718,100...35,892,578
Ensembl chr 2:35,718,889...35,870,578
JBrowse link
G Spr sepiapterin reductase ISO MGI:MGI:3757641 (MGI:MGI:3722569|PMID:16532389) RGD PMID:16532389 MGI:MGI:3722569 NCBI chr 4:116,912,343...116,916,073
Ensembl chr 4:116,912,351...116,916,236
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IEP RGD PMID:15936112 RGD:4891926 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756
JBrowse link
thyroid hormone catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dio2 iodothyronine deiodinase 2 ISO MGI:MGI:2182450 (MGI:MGI:2154044|PMID:11731615) RGD PMID:11731615 MGI:MGI:2154044 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Dio3 iodothyronine deiodinase 3 ISO MGI:MGI:2664293 (MGI:MGI:3615073|PMID:16410833), (MGI:MGI:4441081|PMID:20203194), (MGI:MGI:5578402|PMID:25002520) RGD PMID:16410833, PMID:20203194, PMID:25002520 MGI:MGI:3615073, MGI:MGI:4441081, MGI:MGI:5578402 NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138
JBrowse link
thyroid hormone generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cga glycoprotein hormones, alpha polypeptide ISO
IBA
MGI:MGI:1857152 (MGI:MGI:1316794|PMID:12114718)
PMID:21873635
RGD PMID:12114718, PMID:21873635 MGI:MGI:1316794, RGD:13792537 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
JBrowse link
G Cpq carboxypeptidase Q IDA
IBA
PMID:22127294
PMID:21873635
UniProt
GO_Central
PMID:22127294, PMID:21873635 RGD:8554022, RGD:13792537 NCBI chr 7:71,709,174...72,167,413
Ensembl chr 7:71,709,157...72,167,417
JBrowse link
G Ctsb cathepsin B IEA
ISO
GO_REF:0000107
(MGI:MGI:2664014|PMID:12782676)
Ensembl
RGD
PMID:12782676 GO_REF:0000107, MGI:MGI:2664014 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsk cathepsin K ISS
ISO
GO_REF:0000024
(MGI:MGI:2664014|PMID:12782676)
(PMID:11082042)
UniProt
RGD
PMID:11082042, PMID:12782676 GO_REF:0000024, MGI:MGI:2664014 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Ctsl cathepsin L ISO (MGI:MGI:2664014|PMID:12782676) RGD PMID:12782676 MGI:MGI:2664014 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Dio2 iodothyronine deiodinase 2 IDA RGD PMID:15550511 RGD:1626436 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Duox1 dual oxidase 1 IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 3:114,251,794...114,286,827
Ensembl chr 3:114,253,637...114,286,802
JBrowse link
G Duox2 dual oxidase 2 TAS
IEA
GO_REF:0000041 UniProt PMID:12538618 GO_REF:0000041, RGD:632568 NCBI chr 3:114,218,187...114,237,808
Ensembl chr 3:114,218,193...114,235,933
JBrowse link
G Foxe1 forkhead box E1 ISO MGI:MGI:2181780 (MGI:MGI:1276273|PMID:9697704) RGD PMID:9697704 MGI:MGI:1276273 NCBI chr 5:61,954,549...61,957,357
Ensembl chr 5:61,954,549...61,957,357
JBrowse link
G Med1 mediator complex subunit 1 ISO MGI:MGI:1861125 (MGI:MGI:1355642|PMID:10882104) RGD PMID:10882104 MGI:MGI:1355642 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
JBrowse link
G Slc16a10 solute carrier family 16 member 10 ISO
IEA
MGI:MGI:1203732 (MGI:MGI:5604693|PMID:24248460)
GO_REF:0000107
RGD
Ensembl
PMID:24248460 GO_REF:0000107, MGI:MGI:5604693 NCBI chr20:45,138,433...45,260,155
Ensembl chr20:45,143,453...45,260,119
JBrowse link
G Slc16a2 solute carrier family 16 member 2 ISO
IEA
MGI:MGI:1919722|MGI:MGI:3710233 (MGI:MGI:5604693|PMID:24248460)
GO_REF:0000107
RGD
Ensembl
PMID:24248460 GO_REF:0000107, MGI:MGI:5604693 NCBI chr  X:74,578,600...74,706,068
Ensembl chr  X:74,577,131...74,706,214
JBrowse link
G Slc5a5 solute carrier family 5 member 5 TAS
IEA
GO_REF:0000002 InterPro PMID:8559252 GO_REF:0000002, RGD:68854 NCBI chr16:20,297,414...20,307,401
Ensembl chr16:20,297,414...20,307,400
JBrowse link
G Tg thyroglobulin TAS
IEA
ISO
IBA
IDA
GO_REF:0000107
(PMID:32025030)
PMID:21873635
(MGI:MGI:2664014|PMID:12782676)
(PMID:11082042), (PMID:12387814)
Ensembl
RGD
PMID:11082042, PMID:12387814, PMID:12782676, PMID:32025030, PMID:11884402, PMID:21873635, PMID:3953233 GO_REF:0000107, MGI:MGI:2664014, RGD:728752, RGD:13792537, RGD:1600150 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Tpo thyroid peroxidase TAS
ISO
IEA
(PMID:12387814)
GO_REF:0000041
RGD
UniProt
PMID:12387814, PMID:15917231 GO_REF:0000041, RGD:1599649 NCBI chr 6:49,020,918...49,089,855
Ensembl chr 6:49,021,044...49,089,855
JBrowse link
thyroid hormone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC118957.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 6:114,478,293...114,488,880 JBrowse link
G Crym crystallin, mu ISO
IBA
IEA
MGI:MGI:3703787 (MGI:MGI:3703173|PMID:17264173)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:17264173, PMID:21873635 GO_REF:0000107, MGI:MGI:3703173, RGD:13792537 NCBI chr 1:189,944,895...189,960,069
Ensembl chr 1:189,944,895...189,960,073
JBrowse link
G Dio1 iodothyronine deiodinase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Dio2 iodothyronine deiodinase 2 TAS
IBA
ISO
IDA
PMID:21873635
(PMID:19651899)
RGD PMID:19651899, PMID:11934678, PMID:21873635, PMID:15550511 RGD:628323, RGD:13792537, RGD:1626436 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Dio3 iodothyronine deiodinase 3 TAS
IBA
ISO
PMID:21873635
UniProtKB:P36021 (PMID:26305885)
RGD PMID:26305885, PMID:7622463, PMID:21873635 RGD:68236, RGD:13792537 NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138
JBrowse link
G Duox2 dual oxidase 2 ISO MGI:MGI:3712359 (MGI:MGI:3712355|PMID:17440044) RGD PMID:17440044 MGI:MGI:3712355 NCBI chr 3:114,218,187...114,237,808
Ensembl chr 3:114,218,193...114,235,933
JBrowse link
G Gcnt4 glucosaminyl (N-acetyl) transferase 4 ISO
IEA
MGI:MGI:3849682 (MGI:MGI:3849361|PMID:19349303)
GO_REF:0000107
RGD
Ensembl
PMID:19349303 GO_REF:0000107, MGI:MGI:3849361 Ensembl chr 2:27,713,880...27,780,119 JBrowse link
G Iyd iodotyrosine deiodinase ISO
IBA
ISS
(PMID:25395621)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:25395621, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:40,086,513...40,100,966
Ensembl chr 1:40,086,470...40,101,840
JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 ISO MGI:MGI:1856525 RGD MGI:MGI:85368 NCBI chr11:35,011,007...35,262,362
Ensembl chr11:35,024,196...35,099,383
JBrowse link
G Reln reelin ISO MGI:MGI:1856398 RGD MGI:MGI:85368 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Slc16a2 solute carrier family 16 member 2 ISO UniProtKB:P55073 (PMID:26305885) RGD PMID:26305885 NCBI chr  X:74,578,600...74,706,068
Ensembl chr  X:74,577,131...74,706,214
JBrowse link
G Slco4a1 solute carrier organic anion transporter family, member 4a1 IDA RGD PMID:11316767 RGD:727314 NCBI chr 3:175,838,994...175,857,985
Ensembl chr 3:175,838,994...175,857,983
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 ISO (PMID:9443824) RGD PMID:9443824 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
JBrowse link
G Tg thyroglobulin ISO MGI:MGI:1856829 (MGI:MGI:57033|PMID:3803305) RGD PMID:3803305 MGI:MGI:57033 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Ttr transthyretin TAS RGD PMID:11995998 RGD:737655 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      cellular metabolic process 11065
        cellular aromatic compound metabolic process 5708
          phenol-containing compound metabolic process 123
            (+)-lariciresinol metabolic process + 0
            (+)-larreatricin metabolic process 0
            (+)-pinoresinol metabolic process + 0
            (+)-secoisolariciresinol metabolic process + 0
            (-)-lariciresinol metabolic process + 0
            (-)-pinoresinol metabolic process + 0
            (-)-secoisolariciresinol metabolic process + 0
            (R)-4-hydroxymandelate metabolic process + 0
            1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process + 0
            2-hydroxybenzoyl-CoA metabolic process + 0
            3-hydroxybenzyl alcohol metabolic process 0
            3-hydroxyphenylacetate metabolic process + 0
            4-hydroxyphenylacetate metabolic process + 0
            4-nitrophenol metabolic process + 2
            F-9775A metabolic process + 0
            F-9775B metabolic process + 0
            actinorhodin metabolic process + 0
            aerobic phenol-containing compound metabolic process + 0
            anaerobic phenol-containing compound metabolic process + 0
            asperthecin metabolic process + 0
            averantin metabolic process + 0
            bromoxynil metabolic process 0
            catechol-containing compound metabolic process + 59
            cresol metabolic process + 0
            curcumin metabolic process + 0
            diorcinol metabolic process + 0
            emericellin metabolic process + 0
            emodin metabolic process + 0
            endocrocin metabolic process + 0
            eugenol metabolic process + 0
            ferulate metabolic process + 0
            fonsecin metabolic process + 0
            funalenone metabolic process + 0
            gallate metabolic process + 0
            homogentisate metabolic process + 1
            melanin metabolic process + 22
            monodictyphenone metabolic process + 0
            neosartoricin metabolic process + 0
            novobiocin metabolic process + 0
            o-orsellinic acid metabolic process + 0
            octopamine metabolic process + 3
            orcinol metabolic process + 0
            pentachlorophenol metabolic process + 0
            phenol metabolic process + 0
            phenol-containing compound biosynthetic process + 49
            phenol-containing compound catabolic process + 10
            pyochelin metabolic process + 0
            resorcinol metabolic process 0
            salicylic acid metabolic process + 0
            serotonin metabolic process + 14
            shamixanthone metabolic process + 0
            sinapate ester metabolic process + 0
            sinapate metabolic process + 0
            thyroid hormone metabolic process + 32
            vanillin metabolic process + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.