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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of melanin biosynthetic process
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Accession:GO:0048022 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
Synonyms:exact_synonym: down regulation of melanin biosynthetic process;   downregulation of melanin biosynthetic process;   negative regulation of melanin anabolism;   negative regulation of melanin biosynthesis;   negative regulation of melanin formation;   negative regulation of melanin synthesis
 narrow_synonym: inhibition of melanin biosynthetic process



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negative regulation of melanin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfsd12 major facilitator superfamily domain containing 12 involved_in ISO (MGI:5912387|PMID:29025994) RGD PMID:29025994 MGI:5912387 NCBI chr 7:8,345,171...8,354,050
Ensembl chr 7:8,347,314...8,353,988
JBrowse link
G Opn3 opsin 3 involved_in ISO (PMID:31097585) RGD PMID:31097585 NCBI chr13:87,589,330...87,619,847
Ensembl chr13:87,589,333...87,619,847
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5499726|PMID:16272156)
UniProt
RGD
PMID:16272156 GO_REF:0000024 MGI:5499726 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247
JBrowse link
G Slc24a5 solute carrier family 24 member 5 acts_upstream_of_or_within ISO (MGI:3775882|PMID:18166528) RGD PMID:18166528 MGI:3775882 NCBI chr 3:112,319,305...112,339,231
Ensembl chr 3:112,319,308...112,339,231
JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (MGI:5619434|PMID:23569434) RGD PMID:23569434 MGI:5619434 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    metabolic process 11461
      biosynthetic process 5814
        negative regulation of biosynthetic process 1716
          negative regulation of cellular biosynthetic process 1672
            negative regulation of melanin biosynthetic process 5
Path 2
Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      cellular metabolic process 9699
        cellular aromatic compound metabolic process 5557
          phenol-containing compound metabolic process 129
            phenol-containing compound biosynthetic process 52
              melanin biosynthetic process 23
                regulation of melanin biosynthetic process 15
                  negative regulation of melanin biosynthetic process 5
paths to the root