ONTOLOGY REPORT - ANNOTATIONS
Term: negative regulation of lymphocyte differentiation
Accession: GO:0045620
browse the term
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation.
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms: exact_synonym: down regulation of lymphocyte differentiation; downregulation of lymphocyte differentiation
narrow_synonym: inhibition of lymphocyte differentiation
related_synonym: negative regulation of lymphocyte development
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Fbxo7
F-box protein 7
acts_upstream_of_or_within
ISO
(PMID:21652635)
MGI
PMID:21652635
NCBI chrNW_004624750:1,977,666...1,997,408
Ensembl chrNW_004624750:1,977,761...1,997,231
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Gli3
GLI family zinc finger 3
involved_in
ISO
(MGI:4355451|PMID:19667090)
BHF-UCL
PMID:19667090
MGI:4355451
NCBI chrNW_004624740:18,961,395...19,238,760
Ensembl chrNW_004624740:18,975,596...19,235,900
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Ihh
Indian hedgehog signaling molecule
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624823:5,959,329...5,965,584
Ensembl chrNW_004624823:5,959,448...5,964,769
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Shh
sonic hedgehog signaling molecule
acts_upstream_of_or_within
ISO
(PMID:10981962)
MGI
PMID:10981962
NCBI chrNW_004624800:2,202,986...2,215,309
Ensembl chrNW_004624800:2,203,393...2,212,068
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Flt3
fms related receptor tyrosine kinase 3
acts_upstream_of_or_within
ISO
(PMID:16618805)
MGI
PMID:16618805
NCBI chrNW_004624776:10,407,083...10,516,350
Ensembl chrNW_004624776:10,435,850...10,517,066
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Hmgb3
high mobility group box 3
acts_upstream_of_or_within
ISO
(PMID:12714519)
MGI
PMID:12714519
NCBI chrNW_004624923:1,245,898...1,250,571
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Id2
inhibitor of DNA binding 2
acts_upstream_of_or_within
ISO
(PMID:18523151)
MGI
PMID:18523151
NCBI chrNW_004624846:2,281,292...2,283,596
Ensembl chrNW_004624846:2,277,961...2,283,571
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Sfrp1
secreted frizzled related protein 1
involved_in
ISO
(MGI:3814493|PMID:18941195) (PMID:18941195)
UniProt
PMID:18941195
MGI:3814493
NCBI chrNW_004624780:2,133,105...2,172,301
Ensembl chrNW_004624780:2,132,960...2,174,508
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Cbfb
core-binding factor subunit beta
involved_in
ISO
(MGI:3772948|PMID:18258917)
UniProt
PMID:18258917
MGI:3772948
NCBI chrNW_004624746:19,204,415...19,264,217
Ensembl chrNW_004624746:19,204,392...19,264,194
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Hmgb1
high mobility group box 1
involved_in
ISO
(PMID:22473704)
UniProt
PMID:22473704
NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184
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Runx3
RUNX family transcription factor 3
involved_in
ISO
(MGI:3772948|PMID:18258917)
UniProt
PMID:18258917
MGI:3772948
NCBI chrNW_004624764:9,192,067...9,218,617
Ensembl chrNW_004624764:9,191,556...9,248,252
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Slc4a2
solute carrier family 4 member 2
involved_in
ISO
(MGI:6840447|PMID:24515893)
UniProt
PMID:24515893
MGI:6840447
NCBI chrNW_004624800:5,545,380...5,560,789
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Socs1
suppressor of cytokine signaling 1
involved_in
ISO
(MGI:6140589|PMID:24880459)
UniProt
PMID:24880459
MGI:6140589
NCBI chrNW_004624824:8,444,877...8,446,628
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Zbtb7b
zinc finger and BTB domain containing 7B
involved_in
ISO
(MGI:5446998|PMID:22730529), (MGI:6140589|PMID:24880459)
UniProt
PMID:22730529 PMID:24880459
MGI:5446998 MGI:6140589
NCBI chrNW_004624885:2,474,427...2,489,024
Ensembl chrNW_004624885:2,475,727...2,489,030
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Bmp4
bone morphogenetic protein 4
involved_in
ISO
(PMID:12421925)
BHF-UCL
PMID:12421925
NCBI chrNW_004624731:15,262,480...15,269,196
Ensembl chrNW_004624731:15,263,274...15,269,743
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Clec4g
C-type lectin domain family 4 member G
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:23487419)
Ensembl MGI
PMID:23487419
GO_REF:0000107
NCBI chrNW_004624828:775,114...778,526
Ensembl chrNW_004624828:773,569...778,615
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Erbb2
erb-b2 receptor tyrosine kinase 2
acts_upstream_of_or_within
ISO
(PMID:16230479)
MGI
PMID:16230479
NCBI chrNW_004624795:3,373,313...3,391,509
Ensembl chrNW_004624795:3,373,000...3,391,602
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Ihh
Indian hedgehog signaling molecule
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624823:5,959,329...5,965,584
Ensembl chrNW_004624823:5,959,448...5,964,769
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Tmem131l
transmembrane 131 like
involved_in
ISO
(PMID:23690469)
UniProt
PMID:23690469
NCBI chrNW_004624858:4,772,450...4,931,064
Ensembl chrNW_004624858:4,772,457...4,932,593
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Fgl2
fibrinogen like 2
acts_upstream_of_or_within
ISO
(PMID:29341118)
MGI
PMID:29341118
NCBI chrNW_004624739:26,501,149...26,507,305
Ensembl chrNW_004624739:26,503,965...26,507,305
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Pglyrp1
peptidoglycan recognition protein 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:20709292)
Ensembl MGI
PMID:20709292
GO_REF:0000107
NCBI chrNW_004624832:7,220,739...7,225,146
Ensembl chrNW_004624832:7,221,064...7,224,615
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Pglyrp2
peptidoglycan recognition protein 2
acts_upstream_of_or_within
ISO
(PMID:20709292)
MGI
PMID:20709292
NCBI chrNW_004624901:2,554,303...2,562,436
Ensembl chrNW_004624901:2,554,048...2,561,826
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Bcl6
BCL6 transcription repressor
acts_upstream_of_or_within
ISO
(PMID:15240705)
MGI
PMID:15240705
NCBI chrNW_004624730:69,145,035...69,167,583
Ensembl chrNW_004624730:69,154,080...69,167,689
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Ptpn2
protein tyrosine phosphatase non-receptor type 2
involved_in
ISO
(MGI:5320871|PMID:22080863)
UniProt
PMID:22080863
MGI:5320871
NCBI chrNW_004624770:19,808,400...19,877,494
Ensembl chrNW_004624770:19,808,400...19,876,503
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Cd44
CD44 molecule (IN blood group)
involved_in
ISO
(MGI:5688819|PMID:25065622)
UniProt
PMID:25065622
MGI:5688819
NCBI chrNW_004624767:11,938,452...12,024,970
Ensembl chrNW_004624767:11,938,028...12,025,069
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Ctla4
cytotoxic T-lymphocyte associated protein 4
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624765:12,449,205...12,454,324
Ensembl chrNW_004624765:12,449,205...12,454,324
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Hspb1
heat shock protein family B (small) member 1
ISO
RGD
PMID:30287503
RGD:38549580
NCBI chrNW_004624740:14,940,161...14,941,561
Ensembl chrNW_004624740:14,939,445...14,941,819
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Irf1
interferon regulatory factor 1
involved_in
ISO
(MGI:3803082|PMID:18641303)
UniProt
PMID:18641303
MGI:3803082
NCBI chrNW_004624733:39,596,565...39,603,428
Ensembl chrNW_004624733:39,596,501...39,603,526
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Lag3
lymphocyte activating 3
involved_in
ISO
(MGI:3510279|PMID:15485628)
UniProt
PMID:15485628
MGI:3510279
NCBI chrNW_004624860:3,454,587...3,461,649
Ensembl chrNW_004624860:3,456,347...3,461,592
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Mdk
midkine
involved_in
ISO
(PMID:22323540)
UniProt
PMID:22323540
NCBI chrNW_004624767:2,171,096...2,173,436
Ensembl chrNW_004624767:2,171,096...2,173,512
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Tnfsf4
TNF superfamily member 4
involved_in
ISO
(MGI:3806904|PMID:18713990)
BHF-UCL
PMID:18713990
MGI:3806904
NCBI chrNW_004624771:8,580,489...8,599,735
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Cd74
CD74 molecule
acts_upstream_of_or_within
ISO
(PMID:7679955)
MGI
PMID:7679955
NCBI chrNW_004624774:9,699,876...9,708,871
Ensembl chrNW_004624774:9,700,393...9,709,514
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Dtx1
deltex E3 ubiquitin ligase 1
acts_upstream_of_or_within
ISO
(PMID:12794108)
MGI
PMID:12794108
NCBI chrNW_004624747:19,321,842...19,352,661
Ensembl chrNW_004624747:19,318,465...19,352,473
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Ifnb1
interferon beta 1
involved_in
ISO
(PMID:20554961)
UniProt
PMID:20554961
NCBI chrNW_004624736:25,099,061...25,099,746
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Nrarp
NOTCH regulated ankyrin repeat protein
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:12794108)
Ensembl MGI
PMID:12794108
GO_REF:0000107
NCBI chrNW_004624760:670,796...672,679
Ensembl chrNW_004624760:670,837...671,181
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Prdx2
peroxiredoxin 2
acts_upstream_of_or_within
ISO
(PMID:16290204)
MGI
PMID:16290204
NCBI chrNW_004624901:407,240...410,902
Ensembl chrNW_004624901:406,257...410,866
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Bmp4
bone morphogenetic protein 4
involved_in
ISO
(PMID:12421925)
BHF-UCL
PMID:12421925
NCBI chrNW_004624731:15,262,480...15,269,196
Ensembl chrNW_004624731:15,263,274...15,269,743
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Foxj1
forkhead box J1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624801:6,025,756...6,030,487
Ensembl chrNW_004624801:6,025,793...6,030,486
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Ihh
Indian hedgehog signaling molecule
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624823:5,959,329...5,965,584
Ensembl chrNW_004624823:5,959,448...5,964,769
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Nfkbid
NFKB inhibitor delta
acts_upstream_of_or_within
ISO
(PMID:11931770)
MGI
PMID:11931770
NCBI chrNW_004624794:10,172,789...10,180,693
Ensembl chrNW_004624794:10,168,792...10,179,510
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Rag2
recombination activating 2
ISO
RGD
PMID:30206106
RGD:38508903
NCBI chrNW_004624767:10,678,547...10,680,130
Ensembl chrNW_004624767:10,678,359...10,680,132
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Shh
sonic hedgehog signaling molecule
acts_upstream_of_or_within
ISO
(PMID:10981962)
MGI
PMID:10981962
NCBI chrNW_004624800:2,202,986...2,215,309
Ensembl chrNW_004624800:2,203,393...2,212,068
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Zc3h8
zinc finger CCCH-type containing 8
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624749:137,599...169,641
Ensembl chrNW_004624749:137,721...169,324
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Ascl2
achaete-scute family bHLH transcription factor 2
involved_in
ISO
(MGI:5565031|PMID:24463518)
UniProt
PMID:24463518
MGI:5565031
NCBI chrNW_004624767:15,107,157...15,111,696
Ensembl chrNW_004624767:15,107,159...15,109,191
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Il4r
interleukin 4 receptor
acts_upstream_of_or_within
ISO
(PMID:16424184)
MGI
PMID:16424184
NCBI chrNW_004624782:11,981,781...12,008,362
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Jak3
Janus kinase 3
involved_in
ISO
(MGI:3719947|PMID:16020505)
BHF-UCL
PMID:16020505
MGI:3719947
NCBI chrNW_004624908:1,371,595...1,383,879
Ensembl chrNW_004624908:1,371,595...1,383,879
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Tnfsf4
TNF superfamily member 4
involved_in
ISO
(MGI:4942267|PMID:9670042)
BHF-UCL
PMID:9670042
MGI:4942267
NCBI chrNW_004624771:8,580,489...8,599,735
G
Ascl2
achaete-scute family bHLH transcription factor 2
involved_in
ISO
(MGI:5565031|PMID:24463518)
UniProt
PMID:24463518
MGI:5565031
NCBI chrNW_004624767:15,107,157...15,111,696
Ensembl chrNW_004624767:15,107,159...15,109,191
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Foxp3
forkhead box P3
involved_in
ISO
(PMID:23169781)
UniProt
PMID:23169781
NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679
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Il2
interleukin 2
involved_in
ISO
(MGI:5634593|PMID:25642768)
BHF-UCL
PMID:25642768
MGI:5634593
NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453
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Il4
interleukin 4
acts_upstream_of_or_within
ISO
(PMID:18792410)
MGI
PMID:18792410
NCBI chrNW_004624733:39,412,800...39,420,079
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Rc3h1
ring finger and CCCH-type domains 1
involved_in
ISO
(MGI:6142401|PMID:25282160)
UniProt
PMID:25282160
MGI:6142401
NCBI chrNW_004624771:7,837,547...7,948,217
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Rc3h2
ring finger and CCCH-type domains 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624760:12,025,206...12,074,548
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Smad7
SMAD family member 7
involved_in
ISO
(MGI:5634593|PMID:25642768)
BHF-UCL
PMID:25642768
MGI:5634593
NCBI chrNW_004624778:12,415,364...12,444,882
Ensembl chrNW_004624778:12,415,282...12,444,835
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Tbx21
T-box transcription factor 21
involved_in
ISO
(MGI:4868293|PMID:21151104)
UniProt
PMID:21151104
MGI:4868293
NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143
G
Zbtb7b
zinc finger and BTB domain containing 7B
acts_upstream_of_or_within
ISO
(PMID:23034280)
MGI
PMID:23034280
NCBI chrNW_004624885:2,474,427...2,489,024
Ensembl chrNW_004624885:2,475,727...2,489,030
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Zc3h12a
zinc finger CCCH-type containing 12A
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624764:20,224,919...20,234,108
Ensembl chrNW_004624764:20,224,906...20,234,629
G
Cd69
CD69 molecule
involved_in
ISO
(PMID:24752896)
UniProt
PMID:24752896
NCBI chrNW_004624860:4,345,497...4,364,251
Ensembl chrNW_004624860:4,345,232...4,365,817
G
Jak3
Janus kinase 3
involved_in
ISO
(PMID:20696842)
UniProt
PMID:20696842
NCBI chrNW_004624908:1,371,595...1,383,879
Ensembl chrNW_004624908:1,371,595...1,383,879
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Lgals1
galectin 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624752:10,220,115...10,223,434
Ensembl chrNW_004624752:10,219,872...10,223,317
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Loxl3
lysyl oxidase like 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624749:28,959,682...28,980,428
Ensembl chrNW_004624749:28,960,593...28,980,428
G
Tbx21
T-box transcription factor 21
involved_in
ISO
(MGI:4868293|PMID:21151104)
UniProt
PMID:21151104
MGI:4868293
NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143
G
Tnfsf18
TNF superfamily member 18
involved_in
ISO
(MGI:5551556|PMID:24107315)
UniProt
PMID:24107315
MGI:5551556
NCBI chrNW_004624771:8,711,093...8,722,518
Ensembl chrNW_004624771:8,711,017...8,722,539
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Anxa1
annexin A1
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624811:765,338...782,203
Ensembl chrNW_004624811:764,940...782,198
G
Ascl2
achaete-scute family bHLH transcription factor 2
involved_in
ISO
(MGI:5565031|PMID:24463518)
UniProt
PMID:24463518
MGI:5565031
NCBI chrNW_004624767:15,107,157...15,111,696
Ensembl chrNW_004624767:15,107,159...15,109,191
G
Bcl6
BCL6 transcription repressor
acts_upstream_of_or_within
ISO
(PMID:12594267)
MGI
PMID:12594267
NCBI chrNW_004624730:69,145,035...69,167,583
Ensembl chrNW_004624730:69,154,080...69,167,689
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Hlx
H2.0 like homeobox
acts_upstream_of_or_within
ISO
(PMID:16424184)
MGI
PMID:16424184
NCBI chrNW_004624835:4,223,252...4,227,892
Ensembl chrNW_004624835:4,223,511...4,227,979
G
Socs5
suppressor of cytokine signaling 5
involved_in
ISO
(MGI:3687909|PMID:12242343)
UniProt
PMID:12242343
MGI:3687909
NCBI chrNW_004624738:28,150,004...28,217,850
Ensembl chrNW_004624738:28,150,664...28,216,389
G
Rc3h1
ring finger and CCCH-type domains 1
acts_upstream_of_or_within
ISO
(PMID:15917799)
MGI
PMID:15917799
NCBI chrNW_004624771:7,837,547...7,948,217
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all