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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of T cell differentiation
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Accession:GO:0045581 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of T cell differentiation;   downregulation of T cell differentiation;   negative regulation of T lymphocyte differentiation
 narrow_synonym: inhibition of T cell differentiation
 related_synonym: negative regulation of T cell development



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negative regulation of T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd74 CD74 molecule acts_upstream_of_or_within ISO MGI:1927205 (PMID:7679955) RGD PMID:7679955 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410
JBrowse link
G Dtx1 deltex E3 ubiquitin ligase 1 acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
(PMID:12794108)
Ensembl
RGD
PMID:12794108 GO_REF:0000107 NCBI chr12:41,510,252...41,541,433
Ensembl chr12:41,510,264...41,541,430
JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487
JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:19346497) RGD PMID:19346497 NCBI chr 1:92,926,184...92,927,830 JBrowse link
G Nrarp Notch-regulated ankyrin repeat protein acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
(PMID:12794108)
Ensembl
RGD
PMID:12794108 GO_REF:0000107 NCBI chr 3:28,390,745...28,393,299
Ensembl chr 3:28,390,733...28,393,453
JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO MGI:2668456 (PMID:16290204) RGD PMID:16290204 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006
JBrowse link
negative regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli3 GLI family zinc finger 3 involved_in IEA
ISO
GO_REF:0000107
(PMID:19667090)
Ensembl
RGD
PMID:19667090 GO_REF:0000107 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:54,134,064...54,405,198
JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in IEA
ISO
GO_REF:0000107
(PMID:19109233)
Ensembl
RGD
PMID:19109233 GO_REF:0000107 NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:83,952,986...83,959,203
JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
(PMID:10981962)
Ensembl
RGD
PMID:10981962 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:7,687,846...7,697,901
JBrowse link
negative regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbfb core-binding factor subunit beta involved_in IEA
ISO
GO_REF:0000107
(PMID:18258917)
Ensembl
RGD
PMID:18258917 GO_REF:0000107 NCBI chr19:49,955,133...50,002,661
Ensembl chr19:49,959,096...50,002,657
JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:22473704) RGD PMID:22473704 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327
JBrowse link
G Runx1 RUNX family transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:18258917)
UniProt
RGD
PMID:18258917 GO_REF:0000024 NCBI chr11:45,325,778...45,560,300
Ensembl chr11:45,329,044...45,564,925
JBrowse link
G Runx3 RUNX family transcription factor 3 involved_in ISO (PMID:18258917) RGD PMID:18258917 NCBI chr 5:152,644,270...152,702,835
Ensembl chr 5:152,644,270...152,702,835
JBrowse link
negative regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a2 solute carrier family 4 member 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:24515893)
UniProt
RGD
PMID:24515893 GO_REF:0000024 NCBI chr 4:11,628,860...11,646,961
Ensembl chr 4:11,628,862...11,645,402
JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:24880459)
UniProt
RGD
PMID:24880459 GO_REF:0000024 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847
JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in IEA
ISO
GO_REF:0000107
(PMID:22730529), (PMID:24880459)
Ensembl
RGD
PMID:22730529 PMID:24880459 GO_REF:0000107 NCBI chr 2:177,093,569...177,111,894
Ensembl chr 2:177,095,185...177,109,031
JBrowse link
negative regulation of cytotoxic T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:16493035) RGD PMID:16493035 NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:78,847,685...78,853,326
JBrowse link
negative regulation of immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:12421925)
Ensembl
UniProt
RGD
PMID:12421925 GO_REF:0000024 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:15964995) RGD PMID:15964995 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
JBrowse link
G Clec4g C-type lectin domain family 4, member G acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr12:6,578,266...6,582,913
Ensembl chr12:6,578,258...6,582,894
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
(PMID:16230479)
Ensembl
RGD
PMID:16230479 GO_REF:0000107 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481
JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in IEA
ISO
GO_REF:0000107
(PMID:19109233)
Ensembl
RGD
PMID:19109233 GO_REF:0000107 NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:83,952,986...83,959,203
JBrowse link
G Tmem131l transmembrane 131 like involved_in ISO
IEA
(PMID:23690469)
GO_REF:0000107
RGD
Ensembl
PMID:23690469 GO_REF:0000107 NCBI chr 2:171,555,673...171,689,774
Ensembl chr 2:171,555,673...171,689,733
JBrowse link
negative regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgl2 fibrinogen-like 2 acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:3582343 (PMID:29341118)
Ensembl
RGD
PMID:29341118 GO_REF:0000107 NCBI chr 4:14,602,762...14,608,405
Ensembl chr 4:14,602,771...14,608,405
JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:19346497) RGD PMID:19346497 NCBI chr 1:92,926,184...92,927,830 JBrowse link
negative regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:22080863)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:22080863 GO_REF:0000024 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:63,498,890...63,564,481
JBrowse link
negative regulation of regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule involved_in ISO (PMID:25065622) RGD PMID:25065622 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 involved_in ISO
IEA
IBA
(PMID:18641304)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:18641304 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:69,813,265...69,819,973
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IMP RGD PMID:30287503 RGD:38549580 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
JBrowse link
G Irf1 interferon regulatory factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:18641303)
UniProt
RGD
PMID:18641303 GO_REF:0000024 NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947
JBrowse link
G Lag3 lymphocyte activating 3 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:15485628)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:15485628 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:159,398,930...159,407,001
Ensembl chr 4:159,398,932...159,406,669
JBrowse link
G Mdk midkine involved_in ISO
IEA
ISS
(PMID:22323540)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:22323540 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:98,356,789...98,358,743
JBrowse link
G Mir21 microRNA 21 involved_in ISO RNAcentral:URS0000338542_9606 (PMID:22387553) RGD PMID:22387553 NCBI chr10:71,902,600...71,902,691 JBrowse link
G Mir30b microRNA 30b involved_in ISO RNAcentral:URS000039ED8D_9606 (PMID:22387553) RGD PMID:22387553 NCBI chr 7:102,021,543...102,021,629 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:18713990)
Ensembl
RGD
PMID:18713990 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133
JBrowse link
G Tug1 taurine up-regulated 1 IMP RGD PMID:30287503 RGD:38549580 NCBI chr14:82,743,501...82,750,534
Ensembl chr14:82,746,113...82,750,534
JBrowse link
negative regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO
IEA
(PMID:12421925)
GO_REF:0000107
RGD
Ensembl
PMID:12421925 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172
JBrowse link
G Foxj1 forkhead box J1 involved_in IEA
ISO
GO_REF:0000107
(PMID:16339515)
Ensembl
RGD
PMID:16339515 GO_REF:0000107 NCBI chr10:102,065,163...102,069,945
Ensembl chr10:102,065,170...102,069,241
JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in IEA
ISO
GO_REF:0000107
(PMID:19109233)
Ensembl
RGD
PMID:19109233 GO_REF:0000107 NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:83,952,986...83,959,203
JBrowse link
G Nfkbid NFKB inhibitor delta acts_upstream_of_or_within ISO (PMID:11931770) RGD PMID:11931770 NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:94,808,453...94,817,861
JBrowse link
G Rag2 recombination activating 2 IMP RGD PMID:30206106 RGD:38508903 NCBI chr 3:108,357,399...108,367,186
Ensembl chr 3:108,357,399...108,365,253
JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:7,687,846...7,697,901
JBrowse link
G Zc3h8 zinc finger CCCH type containing 8 involved_in ISO
IEA
(PMID:12153508)
GO_REF:0000107
RGD
Ensembl
PMID:12153508 GO_REF:0000107 NCBI chr 3:136,629,998...136,646,998
Ensembl chr 3:136,629,999...136,646,952
JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:24463518)
Ensembl
RGD
PMID:24463518 GO_REF:0000107 NCBI chr 1:207,578,447...207,665,126
Ensembl chr 1:207,578,449...207,580,856
JBrowse link
G Jak3 Janus kinase 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:16020505)
BHF-UCL
RGD
PMID:16020505 GO_REF:0000024 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in IEA
ISO
GO_REF:0000107
(PMID:9670042)
Ensembl
RGD
PMID:9670042 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133
JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:24463518)
Ensembl
RGD
PMID:24463518 GO_REF:0000107 NCBI chr 1:207,578,447...207,665,126
Ensembl chr 1:207,578,449...207,580,856
JBrowse link
G Foxp3 forkhead box P3 involved_in ISO
IEA
(PMID:23169781)
GO_REF:0000107
RGD
Ensembl
PMID:23169781 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894
JBrowse link
G Il2 interleukin 2 involved_in ISO RNAcentral:URS000039ED8D_10090 (PMID:25642768) RGD PMID:25642768 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:18792410) RGD PMID:18792410 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
JBrowse link
G Pf4 platelet factor 4 IDA RGD PMID:24986443 RGD:329901907 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,582,477...17,583,392
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:25282160)
GO_REF:0000117
Ensembl
RGD
UniProt
PMID:25282160 GO_REF:0000107 GO_REF:0000117 NCBI chr13:75,707,098...75,779,114
Ensembl chr13:75,707,338...75,772,816
JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in IEA
ISO
GO_REF:0000117
(PMID:25282160)
UniProt
RGD
PMID:25282160 GO_REF:0000117 NCBI chr 3:41,531,319...41,596,496
Ensembl chr 3:41,531,617...41,589,715
JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO
GO_REF:0000107
(PMID:25642768)
Ensembl
RGD
PMID:25642768 GO_REF:0000107 NCBI chr18:71,263,508...71,291,849
Ensembl chr18:71,263,508...71,291,849
JBrowse link
G Tbx21 T-box transcription factor 21 involved_in IEA
ISO
GO_REF:0000107
(PMID:21151104)
Ensembl
RGD
PMID:21151104 GO_REF:0000107 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,578,751...82,595,253
JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:3530739 (PMID:23034280)
Ensembl
RGD
PMID:23034280 GO_REF:0000107 NCBI chr 2:177,093,569...177,111,894
Ensembl chr 2:177,095,185...177,109,031
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:25282160)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:25282160 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:142,661,193...142,670,051
Ensembl chr 5:142,661,199...142,669,985
JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd69 Cd69 molecule involved_in ISO (PMID:24752896) RGD PMID:24752896 NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:164,411,485...164,419,509
JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (PMID:20696842) RGD PMID:20696842 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222
JBrowse link
G Lgals1 galectin 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:24752896)
GO_REF:0000107
RGD
Ensembl
PMID:24752896 GO_REF:0000107 NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:112,361,850...112,368,800
JBrowse link
G Loxl3 lysyl oxidase-like 3 involved_in ISO
IEA
(PMID:28065600)
GO_REF:0000117
RGD
UniProt
PMID:28065600 GO_REF:0000117 NCBI chr 4:117,098,358...117,114,673
Ensembl chr 4:117,099,635...117,115,046
JBrowse link
G Stat5a signal transducer and activator of transcription 5A involved_in ISO
IEA
(PMID:20696842)
GO_REF:0000107
RGD
Ensembl
PMID:20696842 GO_REF:0000107 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:86,285,547...86,310,184
JBrowse link
G Tbx21 T-box transcription factor 21 involved_in IEA
ISO
GO_REF:0000107
(PMID:21151104)
Ensembl
RGD
PMID:21151104 GO_REF:0000107 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,578,751...82,595,253
JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in ISO (PMID:24107315) RGD PMID:24107315 NCBI chr13:76,366,790...76,440,673
Ensembl chr13:76,366,771...76,376,608
JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:17008549)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17008549 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831
JBrowse link
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:24463518)
Ensembl
RGD
PMID:24463518 GO_REF:0000107 NCBI chr 1:207,578,447...207,665,126
Ensembl chr 1:207,578,449...207,580,856
JBrowse link
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:96559 (PMID:12594267)
Ensembl
RGD
PMID:12594267 GO_REF:0000107 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047
JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:105367|MGI:2182089 (PMID:16424184)
Ensembl
RGD
PMID:16424184 GO_REF:0000107 NCBI chr13:98,811,852...98,817,264
Ensembl chr13:98,811,856...98,817,264
JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (PMID:12242343) RGD PMID:12242343 NCBI chr 6:13,235,157...13,266,161
Ensembl chr 6:13,234,062...13,273,883
JBrowse link
G Zfp35 zinc finger protein 35 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr18:15,543,604...15,559,084
Ensembl chr18:15,543,516...15,559,837
JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rc3h1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:3581675 (PMID:15917799)
Ensembl
RGD
PMID:15917799 GO_REF:0000107 NCBI chr13:75,707,098...75,779,114
Ensembl chr13:75,707,338...75,772,816
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    immune system process 2920
      leukocyte activation 1068
        lymphocyte activation 867
          lymphocyte differentiation 454
            T cell differentiation 337
              negative regulation of T cell differentiation 59
                negative regulation of T cell differentiation in thymus + 12
                negative regulation of alpha-beta T cell differentiation + 32
                negative regulation of cytotoxic T cell differentiation 1
                negative regulation of extrathymic T cell differentiation 0
                negative regulation of gamma-delta T cell differentiation 0
                negative regulation of memory T cell differentiation 2
                negative regulation of pro-T cell differentiation 0
                negative regulation of regulatory T cell differentiation + 10
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      cellular developmental process 4933
        cell differentiation 4932
          cell development 3418
            hemopoiesis 1096
              leukocyte differentiation 699
                mononuclear cell differentiation 559
                  lymphocyte differentiation 454
                    T cell differentiation 337
                      regulation of T cell differentiation 182
                        negative regulation of T cell differentiation 59
                          negative regulation of T cell differentiation in thymus + 12
                          negative regulation of alpha-beta T cell differentiation + 32
                          negative regulation of cytotoxic T cell differentiation 1
                          negative regulation of extrathymic T cell differentiation 0
                          negative regulation of gamma-delta T cell differentiation 0
                          negative regulation of memory T cell differentiation 2
                          negative regulation of pro-T cell differentiation 0
                          negative regulation of regulatory T cell differentiation + 10
paths to the root