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ONTOLOGY REPORT - ANNOTATIONS

Term:mRNA cis splicing, via spliceosome
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Accession:GO:0045292 term browser browse the term
Definition:The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript.
Synonyms:exact_synonym: nuclear mRNA cis splicing, via spliceosome
 narrow_synonym: nuclear mRNA cis splicing, via U2-type spliceosome
 broad_synonym: splicing

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mRNA cis splicing, via spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUNH9orf78 chromosome unknown C9orf78 homolog involved_in ISO (PMID:35241646) UniProt PMID:35241646 NCBI chrNW_004955513:38,060...43,450
Ensembl chrNW_004955513:38,060...43,450 		JBrowse link
G Dcps decapping enzyme, scavenger involved_in ISO (PMID:18426921) UniProt PMID:18426921 NCBI chrNW_004955412:27,326,946...27,367,455
Ensembl chrNW_004955412:27,326,971...27,367,342 		JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 involved_in ISO (PMID:18426921) UniProt PMID:18426921 NCBI chrNW_004955420:12,979,368...12,992,500
Ensembl chrNW_004955420:12,979,368...12,992,500 		JBrowse link
G Rbm22 RNA binding motif protein 22 involved_in ISO (PMID:22246180) UniProt PMID:22246180 NCBI chrNW_004955415:3,895,272...3,905,801 JBrowse link
G Sde2 SDE2 telomere maintenance homolog involved_in ISO (PMID:34365507) UniProt PMID:34365507 NCBI chrNW_004955489:181,425...210,966
Ensembl chrNW_004955489:180,414...210,900 		JBrowse link
G Wbp4 WW domain binding protein 4 involved_in ISO (PMID:19592703) UniProt PMID:19592703 NCBI chrNW_004955404:51,046,245...51,094,245
Ensembl chrNW_004955404:51,046,177...51,084,272 		JBrowse link
mRNA 5'-splice site recognition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Psip1 PC4 and SRSF1 interacting protein 1 involved_in ISO (PMID:9885563) UniProt PMID:9885563 NCBI chrNW_004955434:18,312,646...18,357,753
Ensembl chrNW_004955434:18,312,646...18,357,761 		JBrowse link
G Sfswap splicing factor SWAP acts_upstream_of_or_within ISO (PMID:8940107) MGI PMID:8940107 NCBI chrNW_004955482:808,684...871,377
Ensembl chrNW_004955482:808,632...871,402 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 involved_in ISO (PMID:8940107), (PMID:9885563) GO_Central PMID:8940107 PMID:9885563 NCBI chrNW_004955451:4,992,634...4,996,619
Ensembl chrNW_004955451:4,992,634...4,999,029 		JBrowse link
G Srsf12 serine and arginine rich splicing factor 12 involved_in ISO (PMID:11684676) UniProt PMID:11684676 NCBI chrNW_004955411:15,851,482...15,918,864 JBrowse link
positive regulation of mRNA cis splicing, via spliceosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif1 eukaryotic translation initiation factor 1 acts_upstream_of_or_within ISO (PMID:16789828) MGI PMID:16789828 NCBI chrNW_004955451:15,978,571...15,980,352 JBrowse link
G Exosc10 exosome component 10 acts_upstream_of_or_within ISO (PMID:16789828) MGI PMID:16789828 NCBI chrNW_004955486:2,601,362...2,626,451
Ensembl chrNW_004955486:2,601,322...2,626,876 		JBrowse link
G Upf1 UPF1 RNA helicase and ATPase acts_upstream_of_or_within ISO (PMID:16789828) MGI PMID:16789828 NCBI chrNW_004955524:2,798,336...2,814,063
Ensembl chrNW_004955524:2,798,336...2,913,176 		JBrowse link
G Upf3a UPF3A regulator of nonsense mediated mRNA decay acts_upstream_of_or_within ISO (PMID:16789828) MGI PMID:16789828 NCBI chrNW_004955404:25,556...36,730 JBrowse link
G Upf3b UPF3B regulator of nonsense mediated mRNA decay acts_upstream_of_or_within ISO (PMID:16789828) MGI PMID:16789828 NCBI chrNW_004955534:176,553...193,033
Ensembl chrNW_004955534:176,522...193,319 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12360
    metabolic process 7487
      primary metabolic process 6455
        RNA processing 583
          mRNA processing 280
            mRNA splicing, via spliceosome 219
              mRNA cis splicing, via spliceosome 15
                cis assembly of pre-catalytic spliceosome 0
                mRNA 5'-splice site recognition + 4
                negative regulation of mRNA cis splicing, via spliceosome 0
                positive regulation of mRNA cis splicing, via spliceosome 5
                regulation of mRNA cis splicing, via spliceosome + 5
Path 2
Term Annotations click to browse term
  biological_process 12360
    metabolic process 7487
      biosynthetic process 5310
        organic substance biosynthetic process 5264
          organic cyclic compound biosynthetic process 3173
            nucleobase-containing compound biosynthetic process 2999
              nucleic acid biosynthetic process 2838
                RNA biosynthetic process 2744
                  RNA processing 583
                    RNA splicing 276
                      RNA splicing, via transesterification reactions 219
                        RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 219
                          mRNA splicing, via spliceosome 219
                            mRNA cis splicing, via spliceosome 15
                              cis assembly of pre-catalytic spliceosome 0
                              mRNA 5'-splice site recognition + 4
                              negative regulation of mRNA cis splicing, via spliceosome 0
                              positive regulation of mRNA cis splicing, via spliceosome 5
                              regulation of mRNA cis splicing, via spliceosome + 5
paths to the root