Sfswap (splicing factor SWAP) - Rat Genome Database

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Gene: Sfswap (splicing factor SWAP) Chinchilla lanigera
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Symbol: Sfswap
Name: splicing factor SWAP
RGD ID: 9025490
Description: INVOLVED IN alternative mRNA splicing, via spliceosome (ortholog); mRNA 5'-splice site recognition (ortholog); negative regulation of mRNA splicing, via spliceosome (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: splicing factor SWAP homolog; splicing factor, suppressor of white-apricot family; splicing factor, suppressor of white-apricot homolog
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955482808,632 - 871,402 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955482808,684 - 871,377 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Sfswap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955482808,632 - 871,402 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955482808,684 - 871,377 (-)NCBIChiLan1.0ChiLan1.0
SFSWAP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812131,711,090 - 131,799,738 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12131,711,081 - 131,799,738 (+)EnsemblGRCh38hg38GRCh38
GRCh3712132,195,635 - 132,284,283 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612130,761,588 - 130,850,235 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412130,861,864 - 130,950,512NCBI
Celera12131,812,182 - 131,900,934 (+)NCBICelera
Cytogenetic Map12q24.33NCBI
HuRef12129,080,987 - 129,170,070 (+)NCBIHuRef
CHM1_112132,010,269 - 132,105,145 (+)NCBICHM1_1
T2T-CHM13v2.012131,753,414 - 131,843,835 (+)NCBIT2T-CHM13v2.0
Sfswap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395129,578,286 - 129,648,448 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5129,578,285 - 129,648,448 (+)EnsemblGRCm39 Ensembl
GRCm385129,501,231 - 129,571,384 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5129,501,221 - 129,571,384 (+)EnsemblGRCm38mm10GRCm38
MGSCv375130,007,106 - 130,077,259 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365129,815,939 - 129,886,092 (+)NCBIMGSCv36mm8
Celera5126,543,991 - 126,614,293 (+)NCBICelera
Cytogenetic Map5G1.3NCBI
cM Map568.13NCBI
Sfswap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81232,745,704 - 32,816,032 (-)NCBIGRCr8
mRatBN7.21227,109,607 - 27,179,941 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1227,109,611 - 27,179,884 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1228,246,004 - 28,316,319 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01228,856,567 - 28,926,883 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01227,918,044 - 27,988,360 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01230,740,563 - 30,811,015 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1230,740,520 - 30,811,054 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,675,284 - 32,745,308 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41228,179,091 - 28,249,425 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11228,039,375 - 28,112,849 (-)NCBI
Celera1228,813,478 - 28,883,636 (-)NCBICelera
Cytogenetic Map12q13NCBI
SFSWAP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210139,799,194 - 139,887,413 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112139,795,885 - 139,883,919 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012129,362,704 - 129,450,678 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112133,793,149 - 133,881,150 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12133,793,300 - 133,880,910 (+)Ensemblpanpan1.1panPan2
SFSWAP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1261,035,059 - 1,104,730 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl261,035,074 - 1,104,694 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha261,083,285 - 1,153,081 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0261,101,263 - 1,171,503 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl261,101,269 - 1,171,494 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1261,038,422 - 1,108,212 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0261,134,994 - 1,204,741 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0261,058,218 - 1,128,003 (-)NCBIUU_Cfam_GSD_1.0
Sfswap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118122,600,083 - 122,666,141 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366602,054,978 - 2,121,279 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366602,055,180 - 2,121,008 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SFSWAP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1423,516,257 - 23,594,257 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11423,516,253 - 23,594,252 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21424,981,763 - 25,059,559 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SFSWAP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111127,086,690 - 127,177,327 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11127,086,668 - 127,177,324 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037117,843,829 - 117,940,423 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sfswap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474727,588,285 - 27,656,660 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474727,588,684 - 27,653,704 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000012293   ⟹   ENSCLAP00000012152
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955482808,632 - 871,402 (-)Ensembl
RefSeq Acc Id: XM_005402976   ⟹   XP_005403033
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955482808,684 - 871,377 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005402977   ⟹   XP_005403034
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955482808,684 - 871,377 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005402978   ⟹   XP_005403035
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955482810,208 - 871,377 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005402980   ⟹   XP_005403037
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955482808,684 - 871,014 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005402981   ⟹   XP_005403038
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955482808,684 - 871,004 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005402983   ⟹   XP_005403040
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955482818,337 - 871,377 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005402984   ⟹   XP_005403041
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955482808,684 - 871,014 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005403034   ⟸   XM_005402977
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VEG6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005403033   ⟸   XM_005402976
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VEG6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005403037   ⟸   XM_005402980
- Peptide Label: isoform X4
- UniProtKB: A0A8C2VEG6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005403041   ⟸   XM_005402984
- Peptide Label: isoform X6
- UniProtKB: A0A8C2VEG6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005403038   ⟸   XM_005402981
- Peptide Label: isoform X4
- UniProtKB: A0A8C2VEG6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005403035   ⟸   XM_005402978
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VEG6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005403040   ⟸   XM_005402983
- Peptide Label: isoform X5
- UniProtKB: A0A8C2VEG6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000012152   ⟸   ENSCLAT00000012293
Protein Domains
SURP motif


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000008380 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000012293 ENTREZGENE
  ENSCLAT00000012293.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.790 UniProtKB/TrEMBL
InterPro Surp UniProtKB/TrEMBL
  SWAP UniProtKB/TrEMBL
  SWAP/Surp_sf UniProtKB/TrEMBL
  SWAP_N_domain UniProtKB/TrEMBL
NCBI Gene Sfswap ENTREZGENE
PANTHER PTHR13161 UniProtKB/TrEMBL
  SPLICING FACTOR, SUPPRESSOR OF WHITE-APRICOT HOMOLOG UniProtKB/TrEMBL
Pfam DRY_EERY UniProtKB/TrEMBL
  Surp UniProtKB/TrEMBL
PROSITE SURP UniProtKB/TrEMBL
SMART DRY_EERY UniProtKB/TrEMBL
  SWAP UniProtKB/TrEMBL
Superfamily-SCOP SSF109905 UniProtKB/TrEMBL
UniProt A0A8C2VEG6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-09-26 Sfswap  splicing factor SWAP    splicing factor SWAP homolog  Symbol and/or name change 5135510 APPROVED
2016-08-03 Sfswap  splicing factor SWAP homolog    splicing factor, suppressor of white-apricot family  Symbol and/or name change 5135510 APPROVED
2015-08-25 Sfswap  splicing factor, suppressor of white-apricot family    splicing factor, suppressor of white-apricot homolog (Drosophila)  Symbol and/or name change 5135510 APPROVED