Srsf1 (serine and arginine rich splicing factor 1)

Gene: Srsf1 (serine and arginine rich splicing factor 1) Chinchilla lanigera

Analyze

Symbol:

Srsf1

Name:

serine and arginine rich splicing factor 1

RGD ID:

8800240

Description:

ENCODES a protein that exhibits DNA topoisomerase binding (ortholog); mRNA binding (ortholog); protein kinase B binding (ortholog); INVOLVED IN alternative mRNA splicing, via spliceosome (ortholog); cardiac muscle contraction (ortholog); cellular response to interleukin-17 (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); Cardiomegaly (ortholog); cervix uteri carcinoma in situ (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); cytoplasm (ortholog); exon-exon junction complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

serine/arginine-rich splicing factor 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	4,992,634 - 4,999,029 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	4,992,634 - 4,996,619 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

Cardiomegaly (ISO)

cervix uteri carcinoma in situ (ISO)

chronic myeloid leukemia (ISO)

clear cell renal cell carcinoma (ISO)

colon cancer (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

human immunodeficiency virus infectious disease (ISO)

intellectual disability (ISO)

Joubert syndrome 1 (ISO)

lung adenocarcinoma (ISO)

Lung Neoplasms (ISO)

lung non-small cell carcinoma (ISO)

lung squamous cell carcinoma (ISO)

myeloid leukemia (ISO)

myocardial infarction (ISO)

myositis (ISO)

Neoplasm Metastasis (ISO)

neurodevelopmental disorder with dysmorphic facies and behavioral abnormalities (ISO)

Ovarian Neoplasms (ISO)

Pituitary Neoplasms (ISO)

renovascular hypertension (ISO)

schizophrenia (ISO)

stomach cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

alternative mRNA splicing, via spliceosome (ISO)

cardiac muscle contraction (ISO)

cellular response to interleukin-17 (ISO)

in utero embryonic development (ISO)

interleukin-17-mediated signaling pathway (ISO)

liver regeneration (ISO)

mRNA 5'-splice site recognition (ISO)

mRNA stabilization (ISO)

oligodendrocyte differentiation (ISO)

positive regulation of RNA splicing (ISO)

protein localization to nucleus (ISO)

protein localization to P-body (ISO)

regulation of RNA splicing (ISO)

RNA splicing (ISO)

signal transduction involved in regulation of gene expression (ISO)

Cellular Component

catalytic step 2 spliceosome (ISO)

cytoplasm (ISO)

exon-exon junction complex (ISO)

nuclear envelope (ISO)

nuclear speck (ISO)

nucleoplasm (ISO)

nucleus (ISO)

Molecular Function

DNA topoisomerase binding (ISO)

mRNA binding (ISO)

protein binding (ISO)

protein kinase B binding (ISO)

RNA binding (ISO)

RS domain binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

spliceosome pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Srsf1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	4,992,634 - 4,999,029 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	4,992,634 - 4,996,619 (+)	NCBI	ChiLan1.0	ChiLan1.0

SRSF1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	57,989,038 - 58,007,246 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	58,000,919 - 58,007,346 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	56,078,280 - 56,084,607 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	53,433,279 - 53,439,706 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	53,435,853 - 53,439,587	NCBI
Celera	17	52,540,069 - 52,546,497 (-)	NCBI		Celera
Cytogenetic Map	17	q22	NCBI
HuRef	17	51,439,237 - 51,445,664 (-)	NCBI		HuRef
CHM1_1	17	56,143,411 - 56,149,838 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	58,863,040 - 58,881,254 (-)	NCBI		T2T-CHM13v2.0

Srsf1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	87,937,325 - 87,944,583 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	87,938,199 - 87,944,581 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	88,046,499 - 88,053,757 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	88,047,373 - 88,053,755 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	87,861,173 - 87,867,259 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	87,863,972 - 87,867,844 (+)	NCBI		MGSCv36	mm8
Celera	11	87,395,560 - 87,401,471 (-)	NCBI		Celera
Cytogenetic Map	11	C	NCBI
cM Map	11	52.4	NCBI

Srsf1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	73,335,519 - 73,342,549 (+)	NCBI		GRCr8
mRatBN7.2	10	72,838,926 - 72,859,066 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	72,839,274 - 72,845,336 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	77,449,632 - 77,455,683 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	76,954,574 - 76,960,625 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	72,419,074 - 72,425,125 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	75,334,200 - 75,341,197 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	75,335,146 - 75,341,197 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	74,759,412 - 74,765,821 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	76,339,824 - 76,344,552 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	71,749,406 - 71,755,457 (+)	NCBI		Celera
Cytogenetic Map	10	q26	NCBI

SRSF1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	74,179,536 - 74,185,632 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	78,975,993 - 78,996,573 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	52,083,676 - 52,087,454 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	56,937,295 - 56,944,874 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	56,937,295 - 56,944,425 (-)	Ensembl	panpan1.1		panPan2

SRSF1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	32,692,517 - 32,696,325 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	32,694,073 - 32,696,285 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	31,930,816 - 31,934,636 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	33,500,269 - 33,504,092 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	33,500,274 - 33,504,046 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	32,284,909 - 32,288,729 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	32,568,190 - 32,572,012 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	32,651,906 - 32,655,725 (-)	NCBI		UU_Cfam_GSD_1.0

Srsf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	32,015,932 - 32,019,748 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936490	5,055,253 - 5,059,116 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936490	5,055,258 - 5,059,118 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SRSF1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	34,272,956 - 34,282,162 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	34,278,363 - 34,282,164 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	35,278,498 - 35,284,062 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SRSF1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	35,392,573 - 35,396,815 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	35,392,873 - 35,394,982 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	6,208,339 - 6,216,079 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005394041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_262578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01043157	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDI01001036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000021674 ⟹ ENSCLAP00000021471

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955451	4,992,634 - 4,999,029 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000021675 ⟹ ENSCLAP00000021472

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955451	4,992,763 - 4,994,830 (+)	Ensembl

RefSeq Acc Id:

XM_005394041 ⟹ XP_005394098

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955451	4,992,634 - 4,996,619 (+)	NCBI

Sequence:

show sequence

CGTGCGCCAAGCAGATAAAGGCGCCATTTTGGAGAGGCCACGGGAGACGTGGTGCCGCTGCGGG
TTCGCTCTGCTGTGCGCTAGGCTTGGTGGGAAGGCCCGTTCTCGAGTCCGCGCTTTTCCGCCGC
CATGTCGGGAGGTGGTGTGATTCGTGGCCCGGCAGGGAACAACGACTGCCGAATCTACGTGGGA
AACTTACCTCCAGACATCCGAACCAAGGACATTGAGGACGTGTTTTATAAATACGGCGCTATCC
GCGACATCGATCTCAAAAATCGCCGCGGGGGACCTCCTTTCGCCTTCGTAGAATTCGAGGACCC
GCGAGACGCGGAAGACGCCGTGTACGGTCGCGACGGCTACGATTACGATGGATACCGTCTGCGG
GTGGAGTTTCCTCGAAGCGGCCGTGGTACAGGCCGAGGCGGCGGCGGGGGTGGAGGTGGTGGAG
CGCCCCGAGGCCGCTATGGCCCCCCATCCAGACGGTCTGAAAACAGAGTGGTTGTCTCTGGACT
TCCTCCAAGTGGAAGCTGGCAGGATTTAAAGGATCACATGCGTGAAGCAGGTGATGTATGTTAT
GCTGATGTTTACCGAGATGGCACTGGTGTCGTGGAGTTTGTACGGAAAGAAGATATGACCTATG
CGGTTCGAAAACTGGATAACACTAAGTTTAGATCTCATGAGGGAGAAACTGCCTACATCCGGGT
TAAAGTTGATGGGCCCAGAAGTCCAAGTTATGGAAGATCTCGATCTCGAAGCCGTAGTCGTAGC
AGAAGCCGTAGCAGAAGCAACAGCAGGAGTCGCAGTTACTCCCCAAGGAGAAGCAGAGGATCAC
CACGCTATTCTCCCCGTCATAGCAGATCTCGCTCTCGTACATAAGATGATTGGTGACACTTTTT
GTAGAACCCATGTTGTATACAGTTTTCCTTTATTCAGTACAATCTTCATTTTTTTAATTCAAAC
TGTTTTGTTCCGAATGGGCTAAAGTGTTTAATTGCATTCTTGTGTAATATCCCCTTGCTCCTAA
CATCTACATTCCCCTCATGTCTTTGACAAATTGTATTTTAAGTGATGTAGACAGGATTGTTTAA
ATTTAGTTAACTCTCCATGCTCTTCAGACTGTGATATTGTGTAAATGTCTATTATGCTCTGGTT
TGTGTGAACTGGGATGTTGGGGGTGTTTGTGGTTATCTTACCTGGGGAAGTTCTTATGTTTATC
TTGCTTTTCATGTGTCTTTCTGTAGACATATCTGAAGAGATGGATTAAGAATGCTTTGGATTAA
GGATTGTGGAGCACATTTCAATCATTTTAGGATTGTCAAAAGGAGGATTGAGGAGGATCAGATC
AATAATGGAGGCAATGGTATGACTCCAAGTGCTATTGTCACAGATGAAATTGGCAGTATTGACC
TTATACTAAAAGGCAAGGGTTGAAAATGAAAAAGAAAATCTAAAAACACTTGTAAACATCTTAT
GCAGTTATCATTAAGCTACAATTGCTTTGCTCTTTAAACCTTTGCAATTGTGGCAAAATAACAT
TGCCCATTTCGTAACTATTTTACTCCCTTCCCCTTTTTTTGTTTTAATAGGGACTAATGTGGGA
AGAACTGGCTAATTGTCACAGTGCTTAGTTACAACTGTTAATGTGTGACCTGCTGTTGGTGTAC
ATGTGGGTACAGGGTGTTTTTAATTCCAATGAGATAGAGTATAATATCAATACTGCTAAATCTG
CATGTCCTCTGTGTGACTGATACGAGCGTTGCTATTTCATTTTTTTAAGACAAAATGAAAGCAA
AATATAGAATTCCAGTGTATTGGTGTAGATAATCTAGTTGGGAGTACTTTTTAAGTCTCATCTT
CCCCTTTAAACTAATATTCATAATTGACTCACGTTTAAGACACTTTAATTTACAAATTAAATTG
CAGATGGGAACATTAGATTTAGTTTAGACTTAGGTGGGTAACAGTATCAGTAAACTTTTCAACT
ACATAACTCTGCAACCACAAAACCTGTAATACGCTGTACAGTAACAAGTGTTGGCATTATCAGT
TGAACTGTAAATATAAAATGCTTCTTCCAGTTAGTCTCTATGATGATTAAGTTTCTAAAATTTA
TCTGAACACCATTCAGAAACTTGTTTTGGGGAATTTGATAGTTATTGATGTACATCTGTTAAAC
TGATGACAGACATAACTCATCATTCCCCAGAAACCTTTTTTGATTACAGTATCTAACATTTTGC
CTCCTCTTTTTTGGTTTTGCTGGTTATAAAGGTTTGGATTGGAGAGGGCTCACTGGATCCCAAT
CCTTGGAGCTGGATCATTGGATTCAAATCATAATGTGGATAGGATAGGGAGGATGAATTACAAG
GATTCATGGAGCGGGATCAGATTACCAGGAACATAGGAGTGGATTCCTGCCCCAACCAAACCGC
ACTCGTGTGGATTTTTTTATTCAACTTAATTGGCTATTCCAAAGATTTTTTTTTTTTTCCTATT
TTTGACGATTGGAGCCCTTAAGATGCACGATGGAATTGAGTTTTGCATTTTTTGGTAAAAGGAG
CAAAGCGAGGACCTGGAGATATACGCTGGAGCAATCTCCTTGGAAGGATTCAGCACGAGTAGAT
GGTAAACACTTAAAGGGGTAAGGGGGGGTTTGTTTAAAATAGTAATCAGTAAGTCACTTCTAAA
TTTAAAGAAAAAAATTGGAGTTGAAGAATGAGTAGGTTTCCAATTGGCTATTGCCGTTTTTTCT
TTGAAAAAATAAACATTTTTTAAAAAACTATGCATGGTTGTCCTTTTTCCTCTTCATGTAAGAT
TTTGACTTGTAACTATCAGTTTAAATAAGATTCTGACTCTTGTGTTTATGTATTAAAGTTTCTT
GAAAGGCAGTCTAATAAATGGTATTAGCCGTCTCTTACTGTTAATTGTGAAAGTCATAAGGGGA
GGATAAAAATTGAGAATAAGATAGTTGTATATGTAATGGCAATTGAGGGGATGATCTAGTTTGA
AAGATAAACTCTTTACTAAAAGTAATTAAAAACTTATTAATGCTG

hide sequence

RefSeq Acc Id:

XR_262578

Type:

NON-CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955451	4,992,634 - 4,996,619 (+)	NCBI

Sequence:

show sequence

CGTGCGCCAAGCAGATAAAGGCGCCATTTTGGAGAGGCCACGGGAGACGTGGTGCCGCTGCGGG
TTCGCTCTGCTGTGCGCTAGGCTTGGTGGGAAGGCCCGTTCTCGAGTCCGCGCTTTTCCGCCGC
CATGTCGGGAGGTGGTGTGATTCGTGGCCCGGCAGGGAACAACGACTGCCGAATCTACGTGGGA
AACTTACCTCCAGACATCCGAACCAAGGACATTGAGGACGTGTTTTATAAATACGGCGCTATCC
GCGACATCGATCTCAAAAATCGCCGCGGGGGACCTCCTTTCGCCTTCGTAGAATTCGAGGACCC
GCGAGACGCGGAAGACGCCGTGTACGGTCGCGACGGCTACGATTACGATGGATACCGTCTGCGG
GTGGAGTTTCCTCGAAGCGGCCGTGGTACAGGCCGAGGCGGCGGCGGGGGTGGAGGTGGTGGAG
CGCCCCGAGGCCGCTATGGCCCCCCATCCAGACGGTCTGAAAACAGAGTGGTTGTCTCTGGACT
TCCTCCAAGTGGAAGCTGGCAGGATTTAAAGGATCACATGCGTGAAGCAGGTGATGTATGTTAT
GCTGATGTTTACCGAGATGGCACTGGTGTCGTGGAGTTTGTACGGAAAGAAGATATGACCTATG
CGGTTCGAAAACTGGATAACACTAAGTTTAGATCTCATGAGGGAGAAACTGCCTACATCCGGGT
TAAAGTTGATGGGCCCAGAAGTCCAAGTTATGGAAGATCTCGATCTCGAAGCCGTAGTCGTAGC
AGAAGCCGTAGCAGAAGCAACAGCAGGAGTCGCAGTTACTCCCCAAGGAGAAGCAGAGGATCAC
CACGCTATTCTCCCCGTCATAGCAGATCTCGCTCTCGTACATAAGATGATTGGTGACACTTTTT
GTAGAACCCATGTTGTATACAGTTTTCCTTTATTCAGTACAATCTTCATTTTTTTAATTCAAAC
TGTTTTGTTCCGAATGGGCTAAAGTGTTTAATTGCATTCTTGTGTAATATCCCCTTGCTCCTAA
CATCTACATTCCCCTCATGTCTTTGACAAATTGTATTTTAAGTGATGTAGACAGGATTGTTTAA
ATTTAGTTAACTCTCCATGCTCTTCAGACTGTGATATTGTGTAAATGTCTATTATGCTCTGGTT
TGTGTGAACTGGGATGTTGGGGGTGTTTGTGGTTATCTTACCTGGGGAAGTTCTTATGTTTATC
TTGCTTTTCATGTGTCTTTCTGTAGACATATCTGAAGAGATGGATTAAGAATGCTTTGGATTAA
GGATTGTGGAGCACATTTCAATCATTTTAGGATTGTCAAAAGGAGGATTGAGGAGGATCAGATC
AATAATGGAGGCAATGGTTTGGATTGGAGAGGGCTCACTGGATCCCAATCCTTGGAGCTGGATC
ATTGGATTCAAATCATAATGTGGATAGGATAGGGAGGATGAATTACAAGGATTCATGGAGCGGG
ATCAGATTACCAGGAACATAGGAGTGGATTCCTGCCCCAACCAAACCGCACTCGTGTGGATTTT
TTTATTCAACTTAATTGGCTATTCCAAAGATTTTTTTTTTTTTCCTATTTTTGACGATTGGAGC
CCTTAAGATGCACGATGGAATTGAGTTTTGCATTTTTTGGTAAAAGGAGCAAAGCGAGGACCTG
GAGATATACGCTGGAGCAATCTCCTTGGAAGGATTCAGCACGAGTAGATGGTAAACACTTAAAG
GGGTAAGGGGGGGTTTGTTTAAAATAGTAATCAGTAAGTCACTTCTAAATTTAAAGAAAAAAAT
TGGAGTTGAAGAATGAGTAGGTTTCCAATTGGCTATTGCCGTTTTTTCTTTGAAAAAATAAACA
TTTTTTAAAAAACTATGCATGGTTGTCCTTTTTCCTCTTCATGTAAGATTTTGACTTGTAACTA
TCAGTTTAAATAAGATTCTGACTCTTGTGTTTATGTATTAAAGTTTCTTGAAAGGCAGTCTAAT
AAATGGTATTAGCCGTCTCTTACTGTTAATTGTGAAAGTCATAAGGGGAGGATAAAAATTGAGA
ATAAGATAGTTGTATATGTAATGGCAATTGAGGGGATGATCTAGTTTGAAAGATAAACTCTTTA
CTAAAAGTAATTAAAAACTTATTAATGCTG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005394098	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000021471
	ENSCLAP00000021471.1
	ENSCLAP00000021472.1

RefSeq Acc Id:

XP_005394098 ⟸ XM_005394041

- UniProtKB:

A0A8C2VVZ4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDP
RDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGL
PPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRV
KVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT

hide sequence

RefSeq Acc Id:

ENSCLAP00000021472 ⟸ ENSCLAT00000021675

RefSeq Acc Id:

ENSCLAP00000021471 ⟸ ENSCLAT00000021674

Protein Domains

RRM

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000014707	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000021674	ENTREZGENE
	ENSCLAT00000021674.1	UniProtKB/TrEMBL
	ENSCLAT00000021675.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.330	UniProtKB/TrEMBL
InterPro	Nucleotide-bd_a/b_plait_sf	UniProtKB/TrEMBL
	RBD_domain_sf	UniProtKB/TrEMBL
	RRM_dom	UniProtKB/TrEMBL
	SRSF1_RRM1	UniProtKB/TrEMBL
	SRSF1_RRM2	UniProtKB/TrEMBL
NCBI Gene	Srsf1	ENTREZGENE
PANTHER	RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN	UniProtKB/TrEMBL
	SERINE_ARGININE-RICH SPLICING FACTOR 1	UniProtKB/TrEMBL
Pfam	RRM_1	UniProtKB/TrEMBL
PROSITE	RRM	UniProtKB/TrEMBL
SMART	RRM	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54928	UniProtKB/TrEMBL
UniProt	A0A8C2VVZ4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2VWD3_CHILA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Srsf1	serine and arginine rich splicing factor 1		serine/arginine-rich splicing factor 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

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Imported Disease Annotations - OMIM

RGD Manual Annotations