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ONTOLOGY REPORT - ANNOTATIONS

Term:replication fork arrest
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Accession:GO:0043111 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.
Comment:See also the biological process term 'site-specific replication termination ; GO:0071170' and its children.
Synonyms:exact_synonym: negative regulation of DNA replication at replication fork barrier;   replication fork blocking;   replication fork stalling


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replication fork arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC120094818 TIMELESS-interacting protein-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:113,693,252...113,694,434
Ensembl chr 9:113,543,173...113,605,998 		JBrowse link
G Slfn9 schlafen family member 9 involved_in ISO (PMID:29395061) RGD PMID:29395061 NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383 		JBrowse link
G Timeless timeless circadian regulator involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738 		JBrowse link
G Tipin timeless interacting protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:64,780,813...64,801,358
Ensembl chr 8:64,780,828...64,801,352
Ensembl chr 9:64,780,828...64,801,352 		JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:113,542,841...113,544,022
Ensembl chr 9:113,543,173...113,605,998 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    cellular process 19536
      metabolic process 12171
        macromolecule metabolic process 9985
          nucleic acid metabolic process 5334
            DNA metabolic process 972
              DNA-templated DNA replication maintenance of fidelity 59
                replication fork arrest 5
                  replication fork arrest at mating type locus 0
                  replication fork arrest at rDNA repeats + 0
                  replication fork arrest at tRNA locus 0
                  replication fork arrest involved in DNA replication termination 0
Path 2
Term Annotations click to browse term
  biological_process 20546
    biological regulation 13834
      regulation of biological process 13389
        regulation of cellular process 13025
          regulation of metabolic process 6832
            regulation of primary metabolic process 5683
              regulation of nucleobase-containing compound metabolic process 4131
                negative regulation of nucleobase-containing compound metabolic process 1552
                  negative regulation of DNA metabolic process 141
                    negative regulation of DNA replication 24
                      negative regulation of DNA-templated DNA replication 11
                        replication fork arrest 5
                          replication fork arrest at mating type locus 0
                          replication fork arrest at rDNA repeats + 0
                          replication fork arrest at tRNA locus 0
                          replication fork arrest involved in DNA replication termination 0
paths to the root