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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of DNA replication
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Accession:GO:0008156 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication.
Synonyms:exact_synonym: down regulation of DNA replication;   downregulation of DNA replication
 narrow_synonym: inhibition of DNA replication
 related_synonym: DNA replication inhibitor


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negative regulation of DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atr ATR serine/threonine kinase involved_in ISO (PMID:14657349) RGD PMID:14657349 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Cdan1 codanin 1 involved_in ISO (PMID:22407294) RGD PMID:22407294 NCBI chr 3:112,660,839...112,676,596
Ensembl chr 3:112,663,383...112,676,556
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO
IEA
(PMID:12671034)
GO_REF:0000107
RGD
Ensembl
PMID:12671034 GO_REF:0000107 NCBI chr10:108,095,131...108,099,483
Ensembl chr10:108,095,131...108,099,483
JBrowse link
G Gmnc geminin coiled-coil domain containing involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:77,237,033...77,247,723
Ensembl chr11:77,239,098...77,246,315
JBrowse link
G Gmnn geminin, DNA replication inhibitor involved_in IBA
ISO
PMID:21873635
(MGI:2388867|PMID:12192004)
(PMID:9635433)
RGD PMID:9635433 PMID:12192004, PMID:21873635 MGI:2388867, RGD:13792537 NCBI chr17:42,302,523...42,310,783
Ensembl chr17:42,302,540...42,310,783
JBrowse link
G Gtpbp4 GTP binding protein 4 involved_in ISO
IEA
ISS
(PMID:17210637)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
HGNC-UCL
PMID:17210637 GO_REF:0000024 GO_REF:0000107 NCBI chr17:63,111,086...63,145,618
Ensembl chr17:63,110,254...63,145,577
JBrowse link
G Hcrt hypocretin neuropeptide precursor IDA in seminiferous tubules at epithelial cycle stage V RGD PMID:16141395 RGD:1600965 NCBI chr10:88,669,216...88,670,430
Ensembl chr10:88,669,214...88,670,430
JBrowse link
G Hmgb1 high mobility group box 1 IDA RGD PMID:18191612 RGD:2316772 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 IMP RGD PMID:12933696 RGD:1626126 NCBI chr 1:166,898,177...166,912,524
Ensembl chr 1:166,899,894...166,912,524
JBrowse link
G Mapk15 mitogen-activated protein kinase 15 IMP RGD PMID:9891064 RGD:632686 NCBI chr 7:117,041,287...117,061,799
Ensembl chr 7:117,055,395...117,061,047
JBrowse link
G Mcidas multiciliate differentiation and DNA synthesis associated cell cycle protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:44,863,246...44,869,732
Ensembl chr 2:44,863,252...44,870,536
JBrowse link
G Pds5a PDS5 cohesin associated factor A involved_in ISO
ISS
(PMID:19907496)
GO_REF:0000024
RGD
UniProt
PMID:19907496 GO_REF:0000024 NCBI chr14:44,185,445...44,282,308
Ensembl chr14:44,185,446...44,280,079
JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in ISO (PMID:14657349) RGD PMID:14657349 NCBI chr 2:30,634,353...30,664,618
Ensembl chr 2:30,634,354...30,664,163
JBrowse link
G Slfn13 schlafen family member 13 involved_in ISO (PMID:29395061) RGD PMID:29395061 NCBI chr10:70,326,157...70,343,024
Ensembl chr10:70,326,157...70,342,492
JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IBA
(PMID:11327863)
PMID:21873635
RGD PMID:11327863, PMID:21873635 RGD:13792537 NCBI chr 5:2,853,455...2,882,731
Ensembl chr 5:2,853,459...2,882,668
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:1926340 (MGI:3032953|PMID:11884608) RGD PMID:11884608 MGI:3032953 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tspyl2 TSPY-like 2 involved_in ISO (PMID:11395479) RGD PMID:11395479 NCBI chr  X:22,408,118...22,413,886
Ensembl chr  X:22,408,118...22,413,741
JBrowse link
G Wapl WAPL cohesin release factor involved_in ISO (PMID:19907496) RGD PMID:19907496 NCBI chr16:11,029,325...11,108,867
Ensembl chr16:11,032,531...11,106,589
JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:17875940) RGD PMID:17875940 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
negative regulation of DNA-dependent DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gmnn geminin, DNA replication inhibitor involved_in ISO (PMID:11125146) RGD PMID:11125146 NCBI chr17:42,302,523...42,310,783
Ensembl chr17:42,302,540...42,310,783
JBrowse link
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 IMP RGD PMID:23800874 RGD:11557986 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Lig3 DNA ligase 3 involved_in ISO (PMID:21878356) RGD PMID:21878356 NCBI chr10:70,134,734...70,158,051
Ensembl chr10:70,134,729...70,158,055
JBrowse link
replication fork arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Msh3 mutS homolog 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:21,790,048...21,931,791
Ensembl chr 2:21,790,044...21,931,720
JBrowse link
G Slfn13 schlafen family member 13 involved_in ISO (PMID:29395061) RGD PMID:29395061 NCBI chr10:70,326,157...70,343,024
Ensembl chr10:70,326,157...70,342,492
JBrowse link
G Timeless timeless circadian regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:2,643,288...2,667,329
Ensembl chr 7:2,643,288...2,667,628
JBrowse link
G Tipin timeless interacting protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:69,753,363...69,768,640
Ensembl chr 8:69,753,373...69,768,305
JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:173,761...174,959
Ensembl chr 5:173,744...174,921
JBrowse link
replication fork protection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1930616 (MGI:2683861|PMID:14681210)
Ensembl
RGD
PMID:14681210 GO_REF:0000107 MGI:2683861 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) RGD PMID:28191891 NCBI chr11:31,834,608...31,847,751
Ensembl chr11:31,837,839...31,847,490
JBrowse link
G Fbh1 F-box DNA helicase 1 involved_in ISO (MGI:5566975|PMID:24108124) RGD PMID:24108124 MGI:5566975 NCBI chr17:70,399,093...70,437,151
Ensembl chr17:70,399,049...70,437,144
JBrowse link
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:79,943,775...79,990,230
Ensembl chr 9:79,944,132...79,990,229
JBrowse link
G Timeless timeless circadian regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:2,643,288...2,667,329
Ensembl chr 7:2,643,288...2,667,628
JBrowse link
G Tipin timeless interacting protein involved_in IBA
IEA
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 8:69,753,363...69,768,640
Ensembl chr 8:69,753,373...69,768,305
JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:173,761...174,959
Ensembl chr 5:173,744...174,921
JBrowse link
G Zfp830 zinc finger protein 830 involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:4950701|PMID:21191184)
PMID:21873635
UniProt
RGD
PMID:21191184, PMID:21873635 GO_REF:0000024 MGI:4950701, RGD:13792537 NCBI chr10:70,118,250...70,119,714
Ensembl chr10:70,118,250...70,119,716
JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 involved_in IBA
ISO
PMID:21873635
(PMID:22704558), (PMID:22705370)
RGD PMID:22704558 PMID:22705370, PMID:21873635 RGD:13792537 NCBI chr13:44,661,375...44,812,430
Ensembl chr13:44,661,398...44,798,543
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19610
    metabolic process 11878
      biosynthetic process 6146
        cellular biosynthetic process 5990
          cellular macromolecule biosynthetic process 5060
            DNA replication 256
              negative regulation of DNA replication 31
                negative regulation of DNA-dependent DNA replication + 15
Path 2
Term Annotations click to browse term
  biological_process 19610
    metabolic process 11878
      organic substance metabolic process 11408
        macromolecule metabolic process 9863
          macromolecule biosynthetic process 5102
            cellular macromolecule biosynthetic process 5060
              DNA replication 256
                regulation of DNA replication 116
                  negative regulation of DNA replication 31
                    negative regulation of DNA-dependent DNA replication + 15
paths to the root