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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of DNA replication
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Accession:GO:0008156 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication.
Synonyms:exact_synonym: down regulation of DNA replication;   downregulation of DNA replication
 narrow_synonym: inhibition of DNA replication
 related_synonym: DNA replication inhibitor



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negative regulation of DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atr ATR serine/threonine kinase involved_in ISO (PMID:14657349) RGD PMID:14657349 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Cdan1 codanin 1 involved_in ISO (PMID:22407294) RGD PMID:22407294 NCBI chr 3:107,675,147...107,689,811
Ensembl chr 3:107,673,645...107,689,773
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (PMID:12671034) RGD PMID:12671034 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589
JBrowse link
G Gmnc geminin coiled-coil domain containing involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:73,836,255...73,847,698
Ensembl chr11:73,814,533...73,847,328
JBrowse link
G Gmnn geminin, DNA replication inhibitor involved_in IBA
ISO
PMID:21873635
(MGI:2388867|PMID:12192004)
(PMID:9635433)
RGD PMID:9635433 PMID:12192004 PMID:21873635 MGI:2388867, RGD:13792537 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
JBrowse link
G Gtpbp4 GTP binding protein 4 involved_in ISO
ISS
(PMID:17210637)
GO_REF:0000024
RGD
HGNC-UCL
PMID:17210637 GO_REF:0000024 NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009
JBrowse link
G Hcrt hypocretin neuropeptide precursor IDA in seminiferous tubules at epithelial cycle stage V RGD PMID:16141395 RGD:1600965 NCBI chr10:85,689,992...85,691,206
Ensembl chr10:85,689,465...85,691,210
JBrowse link
G Hmgb1 high mobility group box 1 IDA RGD PMID:18191612 RGD:2316772 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 IMP RGD PMID:12933696 RGD:1626126 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500
JBrowse link
G Mapk15 mitogen-activated protein kinase 15 IMP RGD PMID:9891064 RGD:632686 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645
JBrowse link
G Mcidas multiciliate differentiation and DNA synthesis associated cell cycle protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:44,636,581...44,643,730
Ensembl chr 2:44,636,856...44,642,601
JBrowse link
G Pds5a PDS5 cohesin associated factor A involved_in ISO
ISS
(PMID:19907496)
GO_REF:0000024
RGD
UniProt
PMID:19907496 GO_REF:0000024 NCBI chr14:42,551,653...42,651,074
Ensembl chr14:42,552,647...42,648,669
JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in ISO (PMID:14657349) RGD PMID:14657349 NCBI chr 2:31,764,260...31,794,542
Ensembl chr 2:31,764,261...31,794,072
JBrowse link
G Slfn13 schlafen family member 13 involved_in ISO (PMID:29395061) RGD PMID:29395061 NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383
JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IBA
(PMID:11327863)
PMID:21873635
RGD PMID:11327863 PMID:21873635 RGD:13792537 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:1926340 (MGI:3032953|PMID:11884608) RGD PMID:11884608 MGI:3032953 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tspyl2 TSPY-like 2 involved_in ISO (PMID:11395479) RGD PMID:11395479 NCBI chr  X:21,439,478...21,445,208
Ensembl chr  X:21,439,478...21,445,089
JBrowse link
G Wapl WAPL cohesin release factor involved_in ISO (PMID:19907496) RGD PMID:19907496 NCBI chr16:10,005,520...10,075,270
Ensembl chr16:10,004,941...10,073,510
JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:17875940) RGD PMID:17875940 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
negative regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:19906994) RGD PMID:19906994 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Gmnn geminin, DNA replication inhibitor involved_in ISO (PMID:11125146), (PMID:19906994) RGD PMID:11125146 PMID:19906994 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
JBrowse link
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 IMP RGD PMID:23800874 RGD:11557986 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Lig3 DNA ligase 3 involved_in ISO (PMID:21878356) RGD PMID:21878356 NCBI chr10:67,717,796...67,741,141
Ensembl chr10:67,717,812...67,798,414
JBrowse link
replication fork arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC120094818 TIMELESS-interacting protein-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:113,693,252...113,694,434
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Slfn13 schlafen family member 13 involved_in ISO (PMID:29395061) RGD PMID:29395061 NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383
JBrowse link
G Timeless timeless circadian regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
JBrowse link
G Tipin timeless interacting protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:64,780,741...64,801,355
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:113,542,841...113,544,022
Ensembl chr 9:113,543,173...113,605,998
JBrowse link
replication fork protection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1930616 (MGI:2683861|PMID:14681210)
Ensembl
RGD
PMID:14681210 GO_REF:0000107 MGI:2683861 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) RGD PMID:28191891 NCBI chr11:30,911,616...30,933,150
Ensembl chr11:30,923,239...30,932,889
JBrowse link
G Fbh1 F-box DNA helicase 1 involved_in ISO (MGI:5566975|PMID:24108124) RGD PMID:24108124 MGI:5566975 NCBI chr17:66,749,506...66,787,590
Ensembl chr17:66,749,534...66,787,590
JBrowse link
G LOC120094818 TIMELESS-interacting protein-like involved_in IEA
IBA
GO_REF:0000104
PMID:21873635
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 9:113,693,252...113,694,434
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:74,239,718...74,286,156
Ensembl chr 9:74,240,241...74,286,146
JBrowse link
G Timeless timeless circadian regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
JBrowse link
G Tipin timeless interacting protein involved_in IBA
IEA
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 8:64,780,741...64,801,355
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:113,542,841...113,544,022
Ensembl chr 9:113,543,173...113,605,998
JBrowse link
G Zfp830 zinc finger protein 830 involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:4950701|PMID:21191184)
PMID:21873635
UniProt
RGD
PMID:21191184 PMID:21873635 GO_REF:0000024 MGI:4950701, RGD:13792537 NCBI chr10:67,701,340...67,702,804
Ensembl chr10:67,701,073...67,704,523
JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 involved_in IBA
ISO
PMID:21873635
(PMID:22704558), (PMID:22705370)
RGD PMID:22704558 PMID:22705370 PMID:21873635 RGD:13792537 NCBI chr13:39,440,653...39,595,782
Ensembl chr13:39,440,889...39,595,670
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20050
    metabolic process 12312
      negative regulation of metabolic process 3384
        negative regulation of macromolecule metabolic process 3148
          negative regulation of DNA metabolic process 161
            negative regulation of DNA replication 32
              negative regulation of DNA-templated DNA replication + 16
Path 2
Term Annotations click to browse term
  biological_process 20050
    metabolic process 12312
      cellular metabolic process 10357
        cellular aromatic compound metabolic process 6021
          nucleobase-containing compound metabolic process 5782
            nucleic acid metabolic process 5189
              DNA metabolic process 1033
                DNA replication 285
                  regulation of DNA replication 143
                    negative regulation of DNA replication 32
                      negative regulation of DNA-templated DNA replication + 16
paths to the root