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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of DNA metabolic process
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Accession:GO:0051053 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.
Synonyms:exact_synonym: down regulation of DNA metabolic process;   downregulation of DNA metabolic process;   negative regulation of DNA metabolism
 narrow_synonym: inhibition of DNA metabolic process



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negative regulation of DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sub1 SUB1 regulator of transcription involved_in ISO (PMID:28369605) RGD PMID:28369605 NCBI chr 2:61,005,646...61,020,486
Ensembl chr 2:61,005,666...61,020,436
Ensembl chr 2:61,005,666...61,020,436
JBrowse link
negative regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dffa DNA fragmentation factor subunit alpha acts_upstream_of_or_within
involved_in
ISO MGI:2179456 (MGI:2182584|PMID:10601318), (MGI:3029597|PMID:14663139)
(PMID:11371636)
(PMID:15572351)
RGD PMID:10601318 PMID:11371636 PMID:14663139 PMID:15572351 MGI:2182584 MGI:3029597 NCBI chr 5:159,540,718...159,553,639
Ensembl chr 5:159,540,715...159,553,633
JBrowse link
G Dffb DNA fragmentation factor subunit beta involved_in ISO
IEA
(PMID:11371636)
GO_REF:0000107
RGD
Ensembl
PMID:11371636 GO_REF:0000107 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628
JBrowse link
G Mir146a microRNA 146a involved_in ISO (PMID:28433754) RGD PMID:28433754 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 IMP RGD PMID:27184051 RGD:13781945 NCBI chr 5:159,910,242...159,928,201
Ensembl chr 5:159,910,242...159,928,180
JBrowse link
G Pam16 presequence translocase associated motor 16 IDA RGD PMID:24069394 RGD:13462066 NCBI chr10:10,942,534...10,950,654
Ensembl chr10:10,943,001...10,950,649
JBrowse link
negative regulation of deoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dffa DNA fragmentation factor subunit alpha involved_in ISO (PMID:19944011) RGD PMID:19944011 NCBI chr 5:159,540,718...159,553,639
Ensembl chr 5:159,540,715...159,553,633
JBrowse link
negative regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 involved_in ISO (PMID:19366699) RGD PMID:19366699 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO
GO_REF:0000024
(PMID:12070119)
UniProt
RGD
PMID:12070119 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Ahr aryl hydrocarbon receptor IDA RGD PMID:12193573 RGD:625678 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ankrd1 ankyrin repeat domain 1 involved_in ISO (PMID:11139470) RGD PMID:11139470 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:19366699) RGD PMID:19366699 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:11595739) RGD PMID:11595739 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Chek1 checkpoint kinase 1 IMP RGD PMID:12429946 RGD:2316115 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Dach1 dachshund family transcription factor 1 involved_in ISO (PMID:16980615) RGD PMID:16980615 NCBI chr15:74,528,122...74,909,811
Ensembl chr15:74,529,208...74,909,922
JBrowse link
G Dnajc2 DnaJ heat shock protein family (Hsp40) member C2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:76992|PMID:7559602)
Ensembl
RGD
PMID:7559602 GO_REF:0000107 MGI:76992 NCBI chr 4:13,270,239...13,297,438
Ensembl chr 4:13,270,191...13,297,431
JBrowse link
G Dusp1 dual specificity phosphatase 1 IDA RGD PMID:10446064 RGD:7771571 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Gdf2 growth differentiation factor 2 involved_in ISO (PMID:19366699) RGD PMID:19366699 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429
JBrowse link
G Gja1 gap junction protein, alpha 1 IDA RGD PMID:14702389 RGD:8662403 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IMP RGD PMID:23271285 RGD:9831181 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435
JBrowse link
G Niban2 niban apoptosis regulator 2 involved_in ISO (PMID:14602737), (PMID:17569660), (PMID:20032057) RGD PMID:14602737 PMID:17569660 PMID:20032057 NCBI chr 3:16,174,674...16,224,293
Ensembl chr 3:16,174,659...16,224,293
JBrowse link
G Nppc natriuretic peptide C IDA RGD PMID:12746286 RGD:1580115 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
JBrowse link
G Rgn regucalcin IMP RGD PMID:11500948 RGD:9590199 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Tp53 tumor protein p53 IMP RGD PMID:11502571 RGD:70312 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
negative regulation of DNA catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgn regucalcin IDA RGD PMID:2001740 RGD:9590215 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
negative regulation of DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dppa3 developmental pluripotency-associated 3 involved_in ISO
ISS
IBA
(MGI:5432962|PMID:22722204), (MGI:5447615|PMID:17143267), (MGI:5465527|PMID:21407207)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:17143267 PMID:21407207 PMID:22722204 PMID:21873635 GO_REF:0000024 MGI:5432962 MGI:5447615 MGI:5465527, RGD:13792537 NCBI chr 4:155,851,461...155,854,845
Ensembl chr 4:155,815,296...155,854,861
JBrowse link
G Dppa3l1 developmental pluripotency associated 3-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:56,421,825...56,422,277
Ensembl chr 8:56,421,825...56,422,277
JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:3046385|PMID:15087456) RGD PMID:15087456 MGI:3046385 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G LOC120096627 developmental pluripotency-associated protein 3-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:69,456,777...69,460,079
Ensembl chr14:69,457,383...69,457,859
JBrowse link
G LOC120096971 developmental pluripotency-associated protein 3-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:27,224,329...27,232,700
Ensembl chr15:27,225,434...27,225,910
JBrowse link
G Trim28 tripartite motif-containing 28 acts_upstream_of_or_within ISO MGI:1928907 (MGI:5319411|PMID:22495301) RGD PMID:22495301 MGI:5319411 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
JBrowse link
negative regulation of DNA endoreduplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 involved_in ISO (PMID:17875940) RGD PMID:17875940 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
negative regulation of DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt3l DNA methyltransferase 3 like involved_in ISO
ISS
(MGI:5553039|PMID:24074865)
GO_REF:0000024
RGD
UniProt
PMID:24074865 GO_REF:0000024 MGI:5553039 NCBI chr20:10,614,933...10,629,516
Ensembl chr20:10,614,934...10,629,516
JBrowse link
G Kmt2a lysine methyltransferase 2A involved_in ISO (PMID:20010842) RGD PMID:20010842 NCBI chr 8:45,116,771...45,193,320
Ensembl chr 8:45,118,814...45,193,181
JBrowse link
negative regulation of DNA recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase involved_in ISO (PMID:9671747) RGD PMID:9671747 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G H1f0 H1.0 linker histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
JBrowse link
G H1f1 H1.1 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,366,268...41,367,011
Ensembl chr17:41,366,268...41,367,011
JBrowse link
G H1f10 H1.10 linker histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:120,440,515...120,444,705
Ensembl chr 4:120,440,870...120,441,448
JBrowse link
G H1f2 H1.2 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,391,106...41,392,611
Ensembl chr17:41,388,477...41,392,635
JBrowse link
G H1f4 H1.4 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,486,634...41,487,293
Ensembl chr17:41,486,560...41,487,403
JBrowse link
G H1f5 H1.5 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,726,189...42,726,857
Ensembl chr17:42,726,127...42,769,160
JBrowse link
G H1f6 H1.6 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,427,365...41,428,109
Ensembl chr17:41,427,323...41,428,119
JBrowse link
G H1f8 H1.8 linker histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:148,993,133...148,998,254
Ensembl chr 4:148,993,133...148,998,254
JBrowse link
G H4f3 H1.3 linker histone, cluster member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,528,576...41,554,586
Ensembl chr17:41,529,667...41,552,334
JBrowse link
G Hils1 histone linker H1 domain, spermatid-specific 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:79,913,525...79,914,321
Ensembl chr10:79,913,480...79,914,321
JBrowse link
G Lig3 DNA ligase 3 acts_upstream_of_or_within ISO MGI:3629052 (MGI:3625660|PMID:16648486) RGD PMID:16648486 MGI:3625660 NCBI chr10:67,717,796...67,741,141
Ensembl chr10:67,717,812...67,798,414
JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:17715146)
MGI:1858055 (MGI:1351797|PMID:10545954), (MGI:74950|PMID:7628020)
GO_REF:0000107
RGD
Ensembl
PMID:7628020 PMID:10545954 PMID:17715146 GO_REF:0000107 MGI:1351797 MGI:74950 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Msh3 mutS homolog 3 involved_in ISO (PMID:17715146) RGD PMID:17715146 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Msh6 mutS homolog 6 involved_in
acts_upstream_of_or_within
ISO (PMID:17715146)
MGI:2151803 (MGI:1351797|PMID:10545954)
RGD PMID:10545954 PMID:17715146 MGI:1351797 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3835812 (MGI:2448116|PMID:12509447) RGD PMID:12509447 MGI:2448116 NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069
JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 involved_in IBA
ISO
PMID:21873635
(MGI:5645200|PMID:22579284)
RGD PMID:22579284 PMID:21873635 MGI:5645200, RGD:13792537 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348
JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 involved_in ISO (PMID:22704558) RGD PMID:22704558 NCBI chr13:39,440,653...39,595,782
Ensembl chr13:39,440,889...39,595,670
JBrowse link
negative regulation of DNA recombination at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pot1b protection of telomeres 1B involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 9:9,670,355...9,728,624
Ensembl chr 9:9,670,362...9,728,532
JBrowse link
G Terf2ip TERF2 interacting protein involved_in ISS
ISO
GO_REF:0000024
(MGI:4440768|PMID:20339076), (MGI:4839412|PMID:20622869)
UniProt
RGD
PMID:20339076 PMID:20622869 GO_REF:0000024 MGI:4440768 MGI:4839412 NCBI chr19:39,976,965...39,984,055
Ensembl chr19:39,976,906...39,984,064
JBrowse link
negative regulation of DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in ISO (MGI:7294462|PMID:35210392) RGD PMID:35210392 MGI:7294462 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496
JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:17049931) RGD PMID:17049931 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
negative regulation of DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atr ATR serine/threonine kinase involved_in ISO (PMID:14657349) RGD PMID:14657349 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Cdan1 codanin 1 involved_in ISO (PMID:22407294) RGD PMID:22407294 NCBI chr 3:107,675,147...107,689,811
Ensembl chr 3:107,673,645...107,689,773
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (PMID:12671034) RGD PMID:12671034 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589
JBrowse link
G Gmnc geminin coiled-coil domain containing involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:73,836,255...73,847,698
Ensembl chr11:73,814,533...73,847,328
JBrowse link
G Gmnn geminin, DNA replication inhibitor involved_in IBA
ISO
PMID:21873635
(MGI:2388867|PMID:12192004)
(PMID:9635433)
RGD PMID:9635433 PMID:12192004 PMID:21873635 MGI:2388867, RGD:13792537 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
JBrowse link
G Gtpbp4 GTP binding protein 4 involved_in ISO
ISS
(PMID:17210637)
GO_REF:0000024
RGD
HGNC-UCL
PMID:17210637 GO_REF:0000024 NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009
JBrowse link
G Hcrt hypocretin neuropeptide precursor IDA in seminiferous tubules at epithelial cycle stage V RGD PMID:16141395 RGD:1600965 NCBI chr10:85,689,992...85,691,206
Ensembl chr10:85,689,465...85,691,210
JBrowse link
G Hmgb1 high mobility group box 1 IDA RGD PMID:18191612 RGD:2316772 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 IMP RGD PMID:12933696 RGD:1626126 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500
JBrowse link
G Mapk15 mitogen-activated protein kinase 15 IMP RGD PMID:9891064 RGD:632686 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645
JBrowse link
G Mcidas multiciliate differentiation and DNA synthesis associated cell cycle protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:44,636,581...44,643,730
Ensembl chr 2:44,636,856...44,642,601
JBrowse link
G Pds5a PDS5 cohesin associated factor A involved_in ISO
ISS
(PMID:19907496)
GO_REF:0000024
RGD
UniProt
PMID:19907496 GO_REF:0000024 NCBI chr14:42,551,653...42,651,074
Ensembl chr14:42,552,647...42,648,669
JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in ISO (PMID:14657349) RGD PMID:14657349 NCBI chr 2:31,764,260...31,794,542
Ensembl chr 2:31,764,261...31,794,072
JBrowse link
G Slfn13 schlafen family member 13 involved_in ISO (PMID:29395061) RGD PMID:29395061 NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383
JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IBA
(PMID:11327863)
PMID:21873635
RGD PMID:11327863 PMID:21873635 RGD:13792537 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:1926340 (MGI:3032953|PMID:11884608) RGD PMID:11884608 MGI:3032953 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tspyl2 TSPY-like 2 involved_in ISO (PMID:11395479) RGD PMID:11395479 NCBI chr  X:21,439,478...21,445,208
Ensembl chr  X:21,439,478...21,445,089
JBrowse link
G Wapl WAPL cohesin release factor involved_in ISO (PMID:19907496) RGD PMID:19907496 NCBI chr16:10,005,520...10,075,270
Ensembl chr16:10,004,941...10,073,510
JBrowse link
negative regulation of DNA-templated DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO (PMID:19906994) RGD PMID:19906994 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Gmnn geminin, DNA replication inhibitor involved_in ISO (PMID:11125146), (PMID:19906994) RGD PMID:11125146 PMID:19906994 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
JBrowse link
negative regulation of double-strand break repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir221 microRNA 221 involved_in ISO (PMID:24147153) RGD PMID:24147153 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:20725033)
UniProt
RGD
PMID:20725033 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:204,387,215...204,395,495
Ensembl chr 1:204,387,215...204,395,483
JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:122,545,029...122,563,651
Ensembl chr 6:122,545,061...122,563,644
JBrowse link
G Rnf169 ring finger protein 169 involved_in ISO (PMID:22492721), (PMID:22733822), (PMID:22742833) RGD PMID:22492721 PMID:22733822 PMID:22742833 NCBI chr 1:154,250,462...154,311,867
Ensembl chr 1:154,254,473...154,311,653
JBrowse link
G Trip12 thyroid hormone receptor interactor 12 involved_in ISO
ISS
(PMID:22884692)
GO_REF:0000024
RGD
UniProt
PMID:22884692 GO_REF:0000024 NCBI chr 9:85,916,691...86,043,312
Ensembl chr 9:85,916,691...86,051,403
JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:17690110) RGD PMID:17690110 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 involved_in ISO
ISS
(PMID:22884692)
GO_REF:0000024
RGD
UniProt
PMID:22884692 GO_REF:0000024 NCBI chr 7:69,116,758...69,224,490
Ensembl chr 7:69,116,761...69,224,903
JBrowse link
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in IBA
ISO
PMID:21873635
(MGI:6241455|PMID:30356214), (MGI:6370284|PMID:31544964)
(PMID:30356214), (PMID:31544964)
RGD PMID:30356214 PMID:31544964 PMID:21873635 MGI:6241455 MGI:6370284, RGD:13792537 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496
JBrowse link
G Fancb FA complementation group B acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:2156841 (MGI:5648586|PMID:25520194)
PMID:21873635
RGD PMID:25520194 PMID:21873635 MGI:5648586, RGD:13792537 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192
JBrowse link
G Fbh1 F-box DNA helicase 1 involved_in ISO (PMID:19736316)
(MGI:5566975|PMID:24108124)
RGD PMID:19736316 PMID:24108124 MGI:5566975 NCBI chr17:66,749,506...66,787,590
Ensembl chr17:66,749,534...66,787,590
JBrowse link
G Helb DNA helicase B involved_in IBA
ISO
PMID:21873635
(MGI:5766842|PMID:26774285)
(PMID:26774285)
RGD PMID:26774285 PMID:21873635 MGI:5766842, RGD:13792537 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585
JBrowse link
G Klhl15 kelch-like family member 15 involved_in ISO
ISS
(PMID:27561354)
(PMID:27561354), (PMID:35219381)
GO_REF:0000024
RGD
UniProt
PMID:27561354 PMID:35219381 GO_REF:0000024 NCBI chr  X:58,994,726...59,050,207
Ensembl chr  X:58,995,461...59,046,069
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693
JBrowse link
G Parpbp PARP1 binding protein involved_in ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
GO_REF:0000002
PMID:21873635
(PMID:22153967)
UniProt
Ensembl
InterPro
RGD
PMID:22153967 PMID:21873635 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 7:22,511,427...22,580,834
Ensembl chr 7:22,511,427...22,573,695
JBrowse link
G Polq DNA polymerase theta involved_in ISO (PMID:25642963)
(MGI:5621198|PMID:25642960)
RGD PMID:25642960 PMID:25642963 MGI:5621198 NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878
JBrowse link
G Radx RPA1 related single stranded DNA binding protein, X-linked involved_in ISO
ISS
(PMID:28735897)
GO_REF:0000024
RGD
UniProt
PMID:28735897 GO_REF:0000024 NCBI chr  X:103,089,284...103,176,840
Ensembl chr  X:103,089,284...103,176,838
JBrowse link
G Recql5 RecQ like helicase 5 acts_upstream_of_or_within ISO MGI:2448558 (MGI:5648586|PMID:25520194) RGD PMID:25520194 MGI:5648586 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652
JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:23333306)
(MGI:5468037|PMID:23306437), (MGI:5476381|PMID:23333305)
RGD PMID:23306437 PMID:23333305 PMID:23333306 MGI:5468037 MGI:5476381 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617
JBrowse link
G Rmi2 RecQ mediated genome instability 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:4,829,333...4,837,264
Ensembl chr10:4,830,553...4,837,235
JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA
(PMID:29656893)
PMID:21873635
RGD PMID:29656893 PMID:21873635 RGD:13792537 NCBI chr 3:119,938,695...120,011,068
Ensembl chr 3:119,938,833...120,009,550
JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965
JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 2:35,294,956...35,301,865
Ensembl chr 2:35,295,859...35,302,346
JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:25294876) RGD PMID:25294876 NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23333306), (PMID:23345425)
(MGI:5476381|PMID:23333305), (MGI:5887194|PMID:20362325)
RGD PMID:20362325 PMID:23333305 PMID:23333306 PMID:23345425 MGI:5476381 MGI:5887194 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
G Ubqln4 ubiquilin 4 involved_in ISO (PMID:30612738) RGD PMID:30612738 NCBI chr 2:174,012,726...174,028,062
Ensembl chr 2:174,012,777...174,028,059
JBrowse link
negative regulation of double-strand break repair via nonhomologous end joining term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aunip aurora kinase A and ninein interacting protein involved_in ISS
ISO
GO_REF:0000024
(PMID:29042561)
UniProt
RGD
PMID:29042561 GO_REF:0000024 NCBI chr 5:146,722,157...146,736,233
Ensembl chr 5:146,722,337...146,736,501
JBrowse link
G Cyren cell cycle regulator of NHEJ involved_in ISO
ISS
IEA
(PMID:28959974)
GO_REF:0000024
GO_REF:0000002
RGD
UniProt
InterPro
PMID:28959974 GO_REF:0000002 GO_REF:0000024 NCBI chr 4:63,547,311...63,553,394
Ensembl chr 4:63,547,335...63,551,602
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) RGD PMID:25820262 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:19549901)
UniProt
RGD
PMID:19549901 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Hsf1 heat shock transcription factor 1 involved_in ISO (PMID:26359349) RGD PMID:26359349 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Nudt16l1 nudix hydrolase 16 like 1 involved_in ISO (PMID:28241136) RGD PMID:28241136 NCBI chr10:10,636,174...10,638,090
Ensembl chr10:10,636,174...10,688,370
JBrowse link
negative regulation of double-strand break repair via single-strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ogg1 8-oxoguanine DNA glycosylase acts_upstream_of_or_within ISO (PMID:19506022) RGD PMID:19506022 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
negative regulation of endodeoxyribonuclease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gzma granzyme A involved_in ISO (PMID:12524539) RGD PMID:12524539 NCBI chr 2:44,740,638...44,752,471
Ensembl chr 2:44,740,569...44,752,493
JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly (ADP-ribose) polymerase family, member 3 involved_in ISO (MGI:6214451|PMID:26000965) RGD PMID:26000965 MGI:6214451 NCBI chr 8:107,111,010...107,117,073
Ensembl chr 8:107,111,012...107,116,782
JBrowse link
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Da2-19 uncharacterized LOC302729 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:44,820,693...44,837,935
Ensembl chr  X:44,820,820...44,837,934
JBrowse link
G Thoc1 THO complex subunit 1 involved_in ISO (MGI:5520039|PMID:22144908) RGD PMID:22144908 MGI:5520039 NCBI chr18:983,606...1,020,379
Ensembl chr18:983,824...1,019,114
JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:103034|MGI:2158438 (MGI:1345885|PMID:10490661) RGD PMID:10490661 MGI:1345885 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (MGI:3695768|PMID:16275384) RGD PMID:16275384 MGI:3695768 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO MGI:3695433 (MGI:3694584|PMID:17137798) RGD PMID:17137798 MGI:3694584 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311
JBrowse link
negative regulation of mitochondrial DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flcn folliculin involved_in ISO (MGI:5463828|PMID:23150719) RGD PMID:23150719 MGI:5463828 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 IMP RGD PMID:23800874 RGD:11557986 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Lig3 DNA ligase 3 involved_in ISO (PMID:21878356) RGD PMID:21878356 NCBI chr10:67,717,796...67,741,141
Ensembl chr10:67,717,812...67,798,414
JBrowse link
negative regulation of mitotic recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankle1 ankyrin repeat and LEM domain containing 1 involved_in ISO UniProtKB:O88700 (MGI:5800654|PMID:27010503) RGD PMID:27010503 MGI:5800654 NCBI chr16:18,076,413...18,082,356
Ensembl chr16:18,076,492...18,083,729
JBrowse link
G Blm BLM RecQ like helicase acts_upstream_of_or_within
involved_in
ISO MGI:1857708|MGI:2158669|MGI:2158670|MGI:3053044|MGI:3663359 (MGI:1312959|PMID:9808625), (MGI:1928200|PMID:11101838), (MGI:3655554|PMID:16914751), (MGI:3700903|PMID:17210642)
UniProtKB:A8VU90 (MGI:5800654|PMID:27010503)
RGD PMID:9808625 PMID:11101838 PMID:16914751 PMID:17210642 PMID:27010503 MGI:1312959 MGI:1928200 MGI:3655554 MGI:3700903 MGI:5800654 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1858054 (MGI:3513725|PMID:15480418)
GO_REF:0000107
RGD
Ensembl
PMID:15480418 GO_REF:0000107 MGI:3513725 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
negative regulation of protection from non-homologous end joining at telomere term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:14690602) RGD PMID:14690602 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 involved_in ISO (MGI:3758502|PMID:14690602) RGD PMID:14690602 MGI:3758502 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 involved_in ISO (MGI:3758502|PMID:14690602) RGD PMID:14690602 MGI:3758502 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808
JBrowse link
negative regulation of t-circle formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO
IBA
(PMID:25620558)
(MGI:5522574|PMID:24115439), (MGI:5645200|PMID:22579284)
PMID:21873635
RGD PMID:22579284 PMID:24115439 PMID:25620558 PMID:21873635 MGI:5522574 MGI:5645200, RGD:13792537 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348
JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:15507207) RGD PMID:15507207 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:19581589) RGD PMID:19581589 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018
JBrowse link
negative regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cers1 ceramide synthase 1 involved_in ISO (PMID:17548428) RGD PMID:17548428 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit NOT|involved_in ISO (PMID:18812185) RGD PMID:18812185 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
JBrowse link
G Mcrs1 microspherule protein 1 involved_in ISO (PMID:15044100) RGD PMID:15044100 NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:130,383,853...130,392,685
JBrowse link
G Men1 menin 1 involved_in ISO (PMID:12837246) RGD PMID:12837246 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:16522649) RGD PMID:16522649 NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200
JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 involved_in ISO (PMID:11701125), (PMID:21119197) RGD PMID:11701125 PMID:21119197 NCBI chr15:38,098,027...38,157,143
Ensembl chr15:38,097,886...38,157,140
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:19567472) RGD PMID:19567472 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Pot1 protection of telomeres 1 involved_in IBA
ISO
PMID:21873635
(PMID:15632080)
RGD PMID:15632080 PMID:21873635 RGD:13792537 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042
JBrowse link
G Pot1b protection of telomeres 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:9,670,355...9,728,624
Ensembl chr 9:9,670,362...9,728,532
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IMP RGD PMID:16556873 RGD:1580657 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Ten1 TEN1 subunit of CST complex involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:101,431,328...101,455,105
Ensembl chr10:101,431,328...101,453,052
JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO UniProtKB:O14746 (PMID:11971978) RGD PMID:11971978 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:10597287) RGD PMID:10597287 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
negative regulation of telomerase RNA reverse transcriptase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly (ADP-ribose) polymerase family, member 3 involved_in ISO (PMID:24528514) RGD PMID:24528514 NCBI chr 8:107,111,010...107,117,073
Ensembl chr 8:107,111,012...107,116,782
JBrowse link
negative regulation of telomere capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:17694070) RGD PMID:17694070 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Nbn nibrin involved_in IEA
ISO
GO_REF:0000107
(PMID:17694070)
Ensembl
RGD
PMID:17694070 GO_REF:0000107 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in ISO
IEA
(PMID:17694070)
GO_REF:0000107
RGD
Ensembl
PMID:17694070 GO_REF:0000107 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
JBrowse link
G Smg6 SMG6 nonsense mediated mRNA decay factor involved_in ISO (PMID:12676087) RGD PMID:12676087 NCBI chr10:59,786,258...60,014,395
Ensembl chr10:59,786,258...60,014,395
JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:24270157) RGD PMID:24270157 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
JBrowse link
negative regulation of telomere maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in ISO (PMID:17055345) RGD PMID:17055345 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:17055345) RGD PMID:17055345 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:17055345) RGD PMID:17055345 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 acts_upstream_of_or_within ISO (MGI:2656398|PMID:12676566) RGD PMID:12676566 MGI:2656398 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984
JBrowse link
negative regulation of telomere maintenance in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtel1 regulator of telomere elongation helicase 1 involved_in ISO (MGI:5645200|PMID:22579284) RGD PMID:22579284 MGI:5645200 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348
JBrowse link
negative regulation of telomere maintenance via recombination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IBA
(PMID:15507207)
(MGI:5883205|PMID:24120135)
PMID:21873635
RGD PMID:15507207 PMID:24120135 PMID:21873635 MGI:5883205, RGD:13792537 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO
IBA
UniProtKB:Q9NUX5 (PMID:15181449), (PMID:15380063)
PMID:21873635
RGD PMID:15181449 PMID:15380063 PMID:21873635 RGD:13792537 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461
JBrowse link
G Ctc1 CST telomere replication complex component 1 involved_in ISO (PMID:22763445) RGD PMID:22763445 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298
JBrowse link
G Dcp2 decapping mRNA 2 involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557
JBrowse link
G Exosc10 exosome component 10 involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr 5:158,995,318...159,018,946
Ensembl chr 5:158,995,313...159,018,940
JBrowse link
G Gnl3l G protein nucleolar 3 like involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr  X:19,961,277...19,994,454
Ensembl chr  X:19,958,603...19,994,508
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) RGD PMID:23935072 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:18082603)
Ensembl
RGD
PMID:18082603 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Nat10 N-acetyltransferase 10 involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr 3:90,111,643...90,151,644
Ensembl chr 3:90,111,645...90,149,927
JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:23657261) RGD PMID:23657261 NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200
JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 involved_in ISO (PMID:11701125), (PMID:21119197) RGD PMID:11701125 PMID:21119197 NCBI chr15:38,098,027...38,157,143
Ensembl chr15:38,097,886...38,157,140
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:19567472) RGD PMID:19567472 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO UniProtKB:Q96AP0 (PMID:15181449) RGD PMID:15181449 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Stn1 STN1 subunit of CST complex involved_in ISO
IEA
(PMID:22763445)
GO_REF:0000107
RGD
Ensembl
PMID:22763445 GO_REF:0000107 NCBI chr 1:246,391,311...246,429,844
Ensembl chr 1:246,395,613...246,429,531
JBrowse link
G Ten1 TEN1 subunit of CST complex involved_in IBA
ISO
PMID:21873635
(PMID:22763445)
RGD PMID:22763445 PMID:21873635 RGD:13792537 NCBI chr10:101,431,328...101,455,105
Ensembl chr10:101,431,328...101,453,052
JBrowse link
G Tent4b terminal nucleotidyltransferase 4B involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537
JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO UniProtKB:O14746 (PMID:11971978) RGD PMID:11971978 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:11971978), (PMID:17055345) RGD PMID:11971978 PMID:17055345 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 involved_in ISO (PMID:10581025), (PMID:15133513) RGD PMID:10581025 PMID:15133513 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984
JBrowse link
negative regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit involved_in ISO (PMID:18812185) RGD PMID:18812185 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
JBrowse link
G Mcrs1 microspherule protein 1 involved_in ISO (PMID:15044100) RGD PMID:15044100 NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:130,383,853...130,392,685
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO (MGI:5705431|PMID:26586427) RGD PMID:26586427 MGI:5705431 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775
JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr10:11,526,563...11,549,291
Ensembl chr10:11,528,424...11,549,295
JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:24012755) RGD PMID:24012755 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
JBrowse link
G Tnks tankyrase involved_in ISO (PMID:25939383) RGD PMID:25939383 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260
JBrowse link
G Tnks2 tankyrase 2 involved_in ISO (PMID:25939383) RGD PMID:25939383 NCBI chr 1:234,567,888...234,621,079
Ensembl chr 1:234,567,858...234,621,079
JBrowse link
negative regulation of telomeric D-loop disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IBA
(PMID:15200954)
PMID:21873635
RGD PMID:15200954 PMID:21873635 RGD:13792537 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IBA
(PMID:15200954)
PMID:21873635
RGD PMID:15200954 PMID:21873635 RGD:13792537 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
JBrowse link
replication fork arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC120094818 TIMELESS-interacting protein-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:113,693,252...113,694,434
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Slfn13 schlafen family member 13 involved_in ISO (PMID:29395061) RGD PMID:29395061 NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383
JBrowse link
G Timeless timeless circadian regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
JBrowse link
G Tipin timeless interacting protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:64,780,741...64,801,355
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:113,542,841...113,544,022
Ensembl chr 9:113,543,173...113,605,998
JBrowse link
replication fork protection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1930616 (MGI:2683861|PMID:14681210)
Ensembl
RGD
PMID:14681210 GO_REF:0000107 MGI:2683861 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) RGD PMID:28191891 NCBI chr11:30,911,616...30,933,150
Ensembl chr11:30,923,239...30,932,889
JBrowse link
G Fbh1 F-box DNA helicase 1 involved_in ISO (MGI:5566975|PMID:24108124) RGD PMID:24108124 MGI:5566975 NCBI chr17:66,749,506...66,787,590
Ensembl chr17:66,749,534...66,787,590
JBrowse link
G LOC120094818 TIMELESS-interacting protein-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:113,693,252...113,694,434
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Smarcal1 Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:74,239,718...74,286,156
Ensembl chr 9:74,240,241...74,286,146
JBrowse link
G Timeless timeless circadian regulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
JBrowse link
G Tipin timeless interacting protein involved_in IBA
IEA
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 8:64,780,741...64,801,355
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:113,542,841...113,544,022
Ensembl chr 9:113,543,173...113,605,998
JBrowse link
G Zfp830 zinc finger protein 830 involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:4950701|PMID:21191184)
PMID:21873635
UniProt
RGD
PMID:21191184 PMID:21873635 GO_REF:0000024 MGI:4950701, RGD:13792537 NCBI chr10:67,701,340...67,702,804
Ensembl chr10:67,701,073...67,704,523
JBrowse link
G Zranb3 zinc finger RANBP2-type containing 3 involved_in IBA
ISO
PMID:21873635
(PMID:22704558), (PMID:22705370)
RGD PMID:22704558 PMID:22705370 PMID:21873635 RGD:13792537 NCBI chr13:39,440,653...39,595,782
Ensembl chr13:39,440,889...39,595,670
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19874
    metabolic process 12191
      negative regulation of metabolic process 3323
        negative regulation of macromolecule metabolic process 3091
          negative regulation of DNA metabolic process 159
            negative regulation of DNA biosynthetic process + 44
            negative regulation of DNA catabolic process + 6
            negative regulation of DNA demethylation 6
            negative regulation of DNA ligation + 0
            negative regulation of DNA methylation 2
            negative regulation of DNA primase activity 0
            negative regulation of DNA recombination + 47
            negative regulation of DNA repair + 33
            negative regulation of DNA replication + 32
            negative regulation of deoxyribonuclease activity + 2
            negative regulation of mitochondrial DNA metabolic process + 3
            negative regulation of mitotic recombination-dependent replication fork processing 0
            negative regulation of t-circle formation 3
            negative regulation of telomere maintenance + 35
            negative regulation of transposon integration 0
Path 2
Term Annotations click to browse term
  biological_process 19874
    metabolic process 12191
      cellular metabolic process 10294
        cellular aromatic compound metabolic process 5989
          nucleobase-containing compound metabolic process 5755
            nucleic acid metabolic process 5178
              DNA metabolic process 1034
                regulation of DNA metabolic process 539
                  negative regulation of DNA metabolic process 159
                    negative regulation of DNA biosynthetic process + 44
                    negative regulation of DNA catabolic process + 6
                    negative regulation of DNA demethylation 6
                    negative regulation of DNA ligation + 0
                    negative regulation of DNA methylation 2
                    negative regulation of DNA primase activity 0
                    negative regulation of DNA recombination + 47
                    negative regulation of DNA repair + 33
                    negative regulation of DNA replication + 32
                    negative regulation of deoxyribonuclease activity + 2
                    negative regulation of mitochondrial DNA metabolic process + 3
                    negative regulation of mitotic recombination-dependent replication fork processing 0
                    negative regulation of t-circle formation 3
                    negative regulation of telomere maintenance + 35
                    negative regulation of transposon integration 0
paths to the root