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ONTOLOGY REPORT - ANNOTATIONS


Term:replication fork arrest
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Accession:GO:0043111 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.
Comment:See also the biological process term 'site-specific replication termination ; GO:0071170' and its children.
Synonyms:exact_synonym: negative regulation of DNA replication at replication fork barrier;   replication fork blocking;   replication fork stalling



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replication fork arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC120094818 TIMELESS-interacting protein-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:113,693,252...113,694,434
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Slfn9 schlafen family member 9 involved_in ISO (PMID:29395061) RGD PMID:29395061 NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383
JBrowse link
G Timeless timeless circadian regulator involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
JBrowse link
G Tipin timeless interacting protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:64,780,813...64,801,358
Ensembl chr 8:64,780,828...64,801,352
JBrowse link
G Tipinl1 TIMELESS interacting protein like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:113,542,841...113,544,022
Ensembl chr 9:113,543,173...113,605,998
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19870
    metabolic process 11602
      macromolecule metabolic process 9394
        nucleic acid metabolic process 5003
          DNA metabolic process 958
            DNA-templated DNA replication maintenance of fidelity 59
              replication fork arrest 5
                replication fork arrest at mating type locus 0
                replication fork arrest at rDNA repeats + 0
                replication fork arrest at tRNA locus 0
                replication fork arrest involved in DNA replication termination 0
Path 2
Term Annotations click to browse term
  biological_process 19870
    metabolic process 11602
      primary metabolic process 10139
        nucleobase-containing compound metabolic process 5585
          nucleic acid metabolic process 5003
            DNA metabolic process 958
              DNA replication 272
                DNA-templated DNA replication 158
                  regulation of DNA-templated DNA replication 38
                    negative regulation of DNA-templated DNA replication 11
                      replication fork arrest 5
                        replication fork arrest at mating type locus 0
                        replication fork arrest at rDNA repeats + 0
                        replication fork arrest at tRNA locus 0
                        replication fork arrest involved in DNA replication termination 0
paths to the root