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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA damage response, signal transduction resulting in transcription
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Accession:GO:0042772 term browser browse the term
Definition:A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription.



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DNA damage response, signal transduction resulting in transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAD2L2 mitotic arrest deficient 2 like 2 involved_in IDA (PMID:17296730) UniProt PMID:17296730 NCBI chr 1:11,674,480...11,691,830
Ensembl chr 1:11,658,918...11,691,811
JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA2 BRCA2 DNA repair associated involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:8738145) Ensembl
MGI
PMID:8738145 GO_REF:0000107 NCBI chr13:32,315,508...32,400,268
Ensembl chr13:32,315,086...32,400,268
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10710310) Ensembl
MGI
PMID:10710310 GO_REF:0000107 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CHEK2 checkpoint kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10710310) Ensembl
MGI
PMID:10710310 GO_REF:0000107 NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422
JBrowse link
G FOXM1 forkhead box M1 involved_in IMP (PMID:17101782) UniProt PMID:17101782 NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174
JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in IDA (PMID:14966270) UniProt PMID:14966270 NCBI chr11:65,712,018...65,719,604
Ensembl chr11:65,711,996...65,719,604
JBrowse link
G RBM38 RNA binding motif protein 38 involved_in IDA (PMID:17050675) UniProt PMID:17050675 NCBI chr20:57,391,396...57,409,333
Ensembl chr20:57,391,396...57,409,333
JBrowse link
G RPS27L ribosomal protein S27 like involved_in IDA (PMID:18056458) UniProt PMID:18056458 NCBI chr15:63,148,249...63,157,477
Ensembl chr15:63,125,872...63,158,021
JBrowse link
G RPS6KA6 ribosomal protein S6 kinase A6 involved_in IMP
IBA
(PMID:15042092) UniProt
GO_Central
PMID:15042092 GO_REF:0000033 NCBI chr  X:84,058,346...84,188,499
Ensembl chr  X:84,058,346...84,206,356
JBrowse link
G TFAP4 transcription factor AP-4 involved_in IDA (PMID:18818310) UniProt PMID:18818310 NCBI chr16:4,257,186...4,273,023
Ensembl chr16:4,257,186...4,273,075
JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
IDA
IMP
ISO
(PMID:16213212)
(PMID:16479015)
(PMID:10710310)
Ensembl
CAFA
UniProt
MGI
PMID:10710310 PMID:16213212 PMID:16479015 GO_REF:0000107 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCBP4 poly(rC) binding protein 4 acts_upstream_of_or_within ISO (PMID:20817677) MGI PMID:20817677 NCBI chr 3:51,957,454...51,967,466
Ensembl chr 3:51,957,454...51,974,016
JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ING4 inhibitor of growth family member 4 involved_in IDA (PMID:15251430) UniProt PMID:15251430 NCBI chr12:6,650,301...6,663,119
Ensembl chr12:6,650,301...6,663,142
JBrowse link
G PYHIN1 pyrin and HIN domain family member 1 involved_in IDA (PMID:16479015) UniProt PMID:16479015 NCBI chr 1:158,931,552...158,990,870
Ensembl chr 1:158,930,796...158,977,059
JBrowse link
G RPL26 ribosomal protein L26 involved_in IMP (PMID:16213212) CAFA PMID:16213212 NCBI chr17:8,377,516...8,383,193
Ensembl chr17:8,377,516...8,383,213
JBrowse link
G ZNF385A zinc finger protein 385A involved_in IMP (PMID:17719541) UniProt PMID:17719541 NCBI chr12:54,369,136...54,391,298
Ensembl chr12:54,369,133...54,391,298
JBrowse link
G ZNHIT1 zinc finger HIT-type containing 1 involved_in IDA (PMID:17700068) UniProt PMID:17700068 NCBI chr 7:101,218,165...101,224,190
Ensembl chr 7:101,218,165...101,224,190
JBrowse link
regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COPS3 COP9 signalosome subunit 3 involved_in IMP (PMID:15861129) UniProt PMID:15861129 NCBI chr17:17,246,616...17,281,246
Ensembl chr17:17,246,616...17,281,273
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19613
    cellular process 18233
      signal transduction 6566
        intracellular signal transduction 2993
          signal transduction in response to DNA damage 205
            DNA damage response, signal transduction resulting in transcription 18
              DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator + 17
Path 2
Term Annotations click to browse term
  biological_process 19613
    biological regulation 13363
      regulation of biological process 12979
        signaling 7170
          signal transduction 6566
            intracellular signal transduction 2993
              signal transduction in response to DNA damage 205
                DNA damage response, signal transduction resulting in transcription 18
                  DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator + 17
paths to the root