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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of toll-like receptor signaling pathway
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Accession:GO:0034121 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway.
Synonyms:exact_synonym: regulation of TLR signaling pathway;   regulation of toll-like receptor signalling pathway

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regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chrNW_004624745:13,904,912...14,159,374
Ensembl chrNW_004624745:13,902,577...14,159,372 		JBrowse link
G Cd36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624739:29,341,620...29,441,232
Ensembl chrNW_004624739:29,407,568...29,441,333 		JBrowse link
G Esr1 estrogen receptor 1 acts_upstream_of_or_within ISO (PMID:22659029) MGI PMID:22659029 NCBI chrNW_004624785:6,164,507...6,601,302
Ensembl chrNW_004624785:6,164,379...6,601,326 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624742:5,260,651...5,271,908
Ensembl chrNW_004624742:5,261,537...5,270,695 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (MGI:6158883|PMID:20616063) UniProt PMID:20616063 MGI:6158883 NCBI chrNW_004624839:4,908,861...5,000,218
Ensembl chrNW_004624839:4,908,639...5,000,677 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624762:25,427,519...25,448,180
Ensembl chrNW_004624762:25,430,926...25,448,114 		JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a CD300a molecule involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chrNW_004624801:4,404,376...4,420,836
Ensembl chrNW_004624801:4,404,262...4,421,097 		JBrowse link
G Cd300lf CD300 molecule like family member f involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chrNW_004624801:4,573,010...4,587,632
Ensembl chrNW_004624801:4,573,010...4,587,592 		JBrowse link
negative regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sarm1 sterile alpha and TIR motif containing 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624786:974,785...1,001,810
Ensembl chrNW_004624786:974,876...997,956 		JBrowse link
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin beta 2 involved_in ISO (MGI:3662828|PMID:16378096) UniProt PMID:16378096 MGI:3662828 NCBI chrNW_004624786:8,568,102...8,576,445
Ensembl chrNW_004624786:8,568,198...8,577,914 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) UniProt PMID:20829348 NCBI chrNW_004624828:6,313,165...6,322,837
Ensembl chrNW_004624828:6,313,867...6,322,764 		JBrowse link
G Gpr108 G protein-coupled receptor 108 involved_in ISO (MGI:6220977|PMID:30332431) UniProt PMID:30332431 MGI:6220977 NCBI chrNW_004624828:3,805,151...3,812,113
Ensembl chrNW_004624828:3,805,366...3,812,055 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (MGI:5896692|PMID:28039360) UniProt PMID:28039360 MGI:5896692 NCBI chrNW_004624786:9,938,384...9,941,210
Ensembl chrNW_004624786:9,938,384...9,941,235 		JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 involved_in ISO (MGI:2183694|PMID:12150927) BHF-UCL PMID:12150927 MGI:2183694 NCBI chrNW_004624802:2,042,486...2,098,921
Ensembl chrNW_004624802:2,047,409...2,098,545 		JBrowse link
G Irf4 interferon regulatory factor 4 acts_upstream_of_or_within ISO (PMID:16236719) MGI PMID:16236719 NCBI chrNW_004624756:23,917,111...23,931,482
Ensembl chrNW_004624756:23,918,323...23,931,501 		JBrowse link
G Lgr4 leucine rich repeat containing G protein-coupled receptor 4 involved_in ISO (MGI:5499954|PMID:23589304) UniProt PMID:23589304 MGI:5499954 NCBI chrNW_004624766:17,110,809...17,147,585
Ensembl chrNW_004624766:17,112,909...17,147,785 		JBrowse link
G Lrrc14 leucine rich repeat containing 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624735:12,337,564...12,345,260 JBrowse link
G Nfkbil1 NFKB inhibitor like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624754:24,639,757...24,652,059
Ensembl chrNW_004624754:24,639,860...24,649,968 		JBrowse link
G Nlrp6 NLR family pyrin domain containing 6 acts_upstream_of_or_within ISO (PMID:22763455) MGI PMID:22763455 NCBI chrNW_004624766:22,143,405...22,150,903 JBrowse link
G Otud4 OTU deubiquitinase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624853:4,091,591...4,145,344
Ensembl chrNW_004624853:4,091,316...4,140,201 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (MGI:4821539|PMID:20584979) UniProt PMID:20584979 MGI:4821539 NCBI chrNW_004624824:279,893...383,220
Ensembl chrNW_004624824:293,374...383,156 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (MGI:5487531|PMID:20728433) UniProt PMID:20728433 MGI:5487531 NCBI chrNW_004624737:8,021,478...8,154,543
Ensembl chrNW_004624737:8,022,836...8,154,422 		JBrowse link
G Rnf115 ring finger protein 115 involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004624772:17,099,593...17,196,258
Ensembl chrNW_004624772:17,104,189...17,196,326 		JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase acid like 3B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624764:11,785,739...11,807,351
Ensembl chrNW_004624764:11,785,640...11,807,084 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in ISO (MGI:3773763|PMID:18083102) UniProt PMID:18083102 MGI:3773763 NCBI chrNW_004624804:8,711,487...8,729,025
Ensembl chrNW_004624804:8,710,821...8,728,072 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004624786:4,080,650...4,135,200
Ensembl chrNW_004624786:4,080,427...4,135,459 		JBrowse link
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdi1 GDP dissociation inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624946:902,831...908,815
Ensembl chrNW_004624946:902,461...909,613 		JBrowse link
G Lrch4 leucine rich repeats and calponin homology domain containing 4 involved_in ISO (MGI:3615854|PMID:16449650) UniProt PMID:16449650 MGI:3615854 NCBI chrNW_004624740:16,491,804...16,503,682
Ensembl chrNW_004624740:16,491,837...16,503,491 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (MGI:5487531|PMID:20728433) UniProt PMID:20728433 MGI:5487531 NCBI chrNW_004624737:8,021,478...8,154,543
Ensembl chrNW_004624737:8,022,836...8,154,422 		JBrowse link
regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf1 interferon regulatory factor 1 involved_in ISO (MGI:3691368|PMID:17018642) UniProt PMID:17018642 MGI:3691368 NCBI chrNW_004624733:39,596,565...39,603,428
Ensembl chrNW_004624733:39,596,501...39,603,526 		JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (MGI:3575992|PMID:15800576) UniProt PMID:15800576 MGI:3575992 NCBI chrNW_004624766:21,850,211...21,853,189 JBrowse link
regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf7 interferon regulatory factor 7 involved_in ISO (MGI:3575992|PMID:15800576) UniProt PMID:15800576 MGI:3575992 NCBI chrNW_004624766:21,850,211...21,853,189 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    cellular process 14237
      signal transduction 5415
        regulation of signal transduction 2810
          regulation of pattern recognition receptor signaling pathway 151
            regulation of toll-like receptor signaling pathway 30
              negative regulation of toll-like receptor signaling pathway + 20
              positive regulation of toll-like receptor signaling pathway + 3
              regulation of MyD88-dependent toll-like receptor signaling pathway + 4
              regulation of MyD88-independent toll-like receptor signaling pathway + 2
              regulation of toll-like receptor 21 signaling pathway + 0
Path 2
Term Annotations click to browse term
  biological_process 15093
    response to stimulus 8161
      response to external stimulus 2128
        response to external biotic stimulus 1317
          response to other organism 1314
            defense response to other organism 906
              defense response to symbiont 802
                innate immune response 664
                  regulation of innate immune response 371
                    positive regulation of innate immune response 309
                      activation of innate immune response 253
                        innate immune response-activating signaling pathway 237
                          pattern recognition receptor signaling pathway 235
                            toll-like receptor signaling pathway 69
                              regulation of toll-like receptor signaling pathway 30
                                negative regulation of toll-like receptor signaling pathway + 20
                                positive regulation of toll-like receptor signaling pathway + 3
                                regulation of MyD88-dependent toll-like receptor signaling pathway + 4
                                regulation of MyD88-independent toll-like receptor signaling pathway + 2
                                regulation of toll-like receptor 21 signaling pathway + 0
paths to the root