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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of actin filament depolymerization
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Accession:GO:0030836 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of actin depolymerization.
Comment:Note that this term was split from 'positive regulation of actin polymerization and/or depolymerization ; GO:0045758' (sibling term 'positive regulation of actin polymerization ; GO:0030838').
Synonyms:exact_synonym: actin filament destabilization;   positive regulation of actin depolymerization;   up regulation of actin filament depolymerization;   upregulation of actin filament depolymerization
 narrow_synonym: activation of actin filament depolymerization;   stimulation of actin filament depolymerization
 broad_synonym: positive regulation of actin polymerization and/or depolymerization
 alt_id: GO:0030045



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positive regulation of actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 acts_upstream_of_or_within
involved_in
ISO (PMID:15548599)
(PMID:23921380)
RGD PMID:15548599 PMID:23921380 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Cfl2 cofilin 2 involved_in ISO (PMID:17160903) RGD PMID:17160903 NCBI chr 6:72,355,664...72,359,709
Ensembl chr 6:72,355,664...72,359,674
JBrowse link
G Dstn destrin, actin depolymerizing factor acts_upstream_of_or_within ISO (PMID:15548599) RGD PMID:15548599 NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:131,284,648...131,311,379
JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:17500066) RGD PMID:17500066 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Pdxp pyridoxal phosphatase involved_in ISO
ISS
IEA
(PMID:15580268)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:15580268 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:110,472,515...110,477,963
Ensembl chr 7:110,472,515...110,477,963
JBrowse link
G Plek pleckstrin involved_in ISO
IEA
(PMID:10497244)
(PMID:19190246)
GO_REF:0000107
RGD
Ensembl
PMID:10497244 PMID:19190246 GO_REF:0000107 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
G Sema5a semaphorin 5A involved_in ISS
ISO
GO_REF:0000024
(PMID:19850054)
UniProt
RGD
PMID:19850054 GO_REF:0000024 NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084
JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:15272027) RGD PMID:15272027 NCBI chr 9:75,991,141...76,018,860
Ensembl chr 9:75,991,141...76,018,858
JBrowse link
G Wdr1 WD repeat domain 1 acts_upstream_of_or_within ISO MGI:101763 (PMID:24840128) RGD PMID:24840128 NCBI chr14:72,258,032...72,291,768
Ensembl chr14:72,257,956...72,291,766
JBrowse link
actin filament uncapping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 involved_in ISO (PMID:25433700) RGD PMID:25433700 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622
JBrowse link
barbed-end actin filament uncapping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (PMID:16054028) RGD PMID:16054028 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (PMID:16054028) RGD PMID:16054028 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) RGD PMID:26466680 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965
JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO
IBA
(PMID:30361697)
GO_REF:0000033
RGD
GO_Central
PMID:30361697 GO_REF:0000033 NCBI chr14:31,284,066...31,520,103
Ensembl chr14:31,284,184...31,522,431
JBrowse link
G Washc2c WASH complex subunit 2C involved_in ISO (PMID:20498093) RGD PMID:20498093 NCBI chr 4:149,267,851...149,325,850
Ensembl chr 4:149,267,924...149,325,851
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      positive regulation of cellular process 6402
        positive regulation of cellular component organization 1305
          positive regulation of supramolecular fiber organization 187
            positive regulation of actin filament depolymerization 14
              actin filament uncapping + 2
              negative regulation of barbed-end actin filament capping 4
Path 2
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      cellular component organization or biogenesis 7176
        cellular component organization 6922
          organelle organization 3701
            cytoskeleton organization 1548
              actin cytoskeleton organization 762
                actin filament organization 493
                  actin polymerization or depolymerization 212
                    regulation of actin polymerization or depolymerization 172
                      regulation of actin filament depolymerization 59
                        positive regulation of actin filament depolymerization 14
                          actin filament uncapping + 2
                          negative regulation of barbed-end actin filament capping 4
paths to the root