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ONTOLOGY REPORT - ANNOTATIONS

Term:protein serine/threonine kinase inhibitor activity
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Accession:GO:0030291 term browser browse the term
Definition:Binds to and stops, prevents or reduces the activity of a protein serine/threonine kinase.


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protein serine/threonine kinase inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 enables ISO PMID:8524413 BHF-UCL PMID:8524413 RGD:8554844 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G AKT1S1 AKT1 substrate 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:106,686,349...106,694,854
Ensembl chr 1:106,687,024...106,693,928 		JBrowse link
G CIB1 calcium and integrin binding 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 3:53,184,713...53,209,195
Ensembl chr 3:53,184,714...53,188,224 		JBrowse link
G CIT citron rho-interacting serine/threonine kinase enables IEA Ensembl GO_REF:0000107 NCBI chr26:15,721,500...15,885,133
Ensembl chr26:15,723,690...15,884,343 		JBrowse link
G DEPTOR DEP domain containing MTOR interacting protein enables IEA Ensembl GO_REF:0000107 NCBI chr13:18,859,526...18,993,464
Ensembl chr13:18,859,634...18,988,583 		JBrowse link
G HTRA2 HtrA serine peptidase 2 enables ISO (PMID:25118933) ParkinsonsUK-UCL PMID:25118933 NCBI chr17:48,610,408...48,613,399
Ensembl chr17:48,610,408...48,613,399 		JBrowse link
G INKA1 inka box actin regulator 1 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr20:39,469,103...39,477,169
Ensembl chr20:39,469,146...39,470,857 		JBrowse link
G INKA2 inka box actin regulator 2 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118
G MACROH2A1 macroH2A.1 histone enables IEA Ensembl GO_REF:0000107 NCBI chr11:23,369,957...23,448,235
Ensembl chr11:23,370,300...23,438,219 		JBrowse link
G PRKCH protein kinase C eta enables ISO (PMID:34593629) UniProt PMID:34593629 NCBI chr 8:36,185,430...36,452,893
Ensembl chr 8:36,219,212...36,451,777 		JBrowse link
G RPTOR regulatory associated protein of MTOR complex 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:1,012,512...1,345,872
Ensembl chr 9:1,013,603...1,344,148 		JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 enables IEA Ensembl GO_REF:0000107 NCBI chr30:5,594,327...5,716,082
Ensembl chr30:5,594,473...5,712,040 		JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 enables ISO (MGI:5318016|PMID:20736167) BHF-UCL PMID:20736167 MGI:5318016 NCBI chr10:64,764,275...64,815,937
Ensembl chr10:64,764,311...64,867,009 		JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 ISO due to an autoinhibitory domain RGD PMID:15081430 RGD:2298791 NCBI chr27:42,764,184...42,914,591
Ensembl chr27:42,765,181...42,912,806 		JBrowse link
cAMP-dependent protein kinase inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FABP7 fatty acid binding protein 7 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr 1:62,084,372...62,088,547
Ensembl chr 1:61,967,129...62,088,547 		JBrowse link
G PKIA cAMP-dependent protein kinase inhibitor alpha enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr29:26,182,842...26,278,838
Ensembl chr29:26,182,876...26,275,883 		JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr 1:61,960,466...62,049,553
Ensembl chr 1:61,967,129...62,088,547 		JBrowse link
G PKIG cAMP-dependent protein kinase inhibitor gamma enables ISO
IEA		 RGD
TreeGrafter
InterPro
UniProt		 PMID:15557275 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 RGD:1359036 NCBI chr24:31,983,131...32,083,307
Ensembl chr24:32,050,242...32,082,919 		JBrowse link
G PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2 enables IEA Ensembl GO_REF:0000107 NCBI chr16:15,521,304...15,786,237
Ensembl chr16:15,522,111...15,785,854 		JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha enables IEA Ensembl GO_REF:0000107 NCBI chr 9:15,180,940...15,203,035
Ensembl chr 9:15,181,393...15,200,683 		JBrowse link
G PRKAR1B protein kinase cAMP-dependent type I regulatory subunit beta enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:16,135,406...16,248,567
Ensembl chr 6:16,135,715...16,247,465 		JBrowse link
G PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:40,277,655...40,388,156
Ensembl chr20:40,277,906...40,384,633 		JBrowse link
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:13,375,216...13,467,811
Ensembl chr18:13,376,425...13,468,038 		JBrowse link
G SMO smoothened, frizzled class receptor enables IEA Ensembl GO_REF:0000107 NCBI chr14:7,518,871...7,527,703
Ensembl chr14:7,518,856...7,528,033 		JBrowse link
G SMPDL3A sphingomyelin phosphodiesterase acid like 3A enables IEA InterPro
UniProt
TreeGrafter		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chr 1:62,091,947...62,110,081
Ensembl chr 1:62,092,121...62,109,773 		JBrowse link
cyclin-dependent protein serine/threonine kinase inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 enables IEA Ensembl GO_REF:0000107 NCBI chr16:45,920,074...45,940,507
Ensembl chr16:45,920,071...45,940,505 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A enables IEA InterPro GO_REF:0000002 NCBI chr12:5,746,898...5,755,103
Ensembl chr12:5,745,852...5,892,281 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B enables IEA
IBA
ISS		 Ensembl
GO_Central
TreeGrafter
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr27:33,609,154...33,613,558
Ensembl chr27:33,611,760...33,612,906 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C enables IEA InterPro GO_REF:0000002 NCBI chr18:46,860,636...46,861,697 JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A enables IEA TreeGrafter GO_REF:0000118 NCBI chr11:41,223,316...41,226,056
Ensembl chr11:41,223,315...41,264,379 		JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B enables ISS
IEA		 UniProt
TreeGrafter
Ensembl		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000118 NCBI chr11:41,259,627...41,264,832 JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:10,219,974...10,224,944
Ensembl chr15:10,220,185...10,224,390 		JBrowse link
G CDKN2D cyclin dependent kinase inhibitor 2D enables IEA Ensembl GO_REF:0000107 NCBI chr20:50,607,382...50,609,929
Ensembl chr20:50,607,674...50,609,482 		JBrowse link
G HEXIM1 HEXIM P-TEFb complex subunit 1 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 9:18,384,811...18,387,981 JBrowse link
G HEXIM2 HEXIM P-TEFb complex subunit 2 enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:18,373,761...18,379,185
Ensembl chr 9:18,373,992...18,377,260 		JBrowse link
G INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 5:31,639,263...31,642,663
Ensembl chr 5:31,639,189...31,642,914 		JBrowse link
G KAT2B lysine acetyltransferase 2B enables IEA Ensembl GO_REF:0000107 NCBI chr23:23,166,722...23,242,447
Ensembl chr23:23,168,600...23,233,478 		JBrowse link
protein kinase C inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPB1 heat shock protein family B (small) member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:7,487,164...7,488,576
Ensembl chr 6:7,487,250...7,488,576 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 18798
    molecular function regulator activity 1950
      enzyme regulator activity 1219
        enzyme inhibitor activity 356
          kinase inhibitor activity 74
            protein kinase inhibitor activity 69
              protein serine/threonine kinase inhibitor activity 38
                cAMP-dependent protein kinase inhibitor activity 11
                cyclin-dependent protein serine/threonine kinase inhibitor activity 12
                protein kinase C inhibitor activity 1
paths to the root