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ONTOLOGY REPORT - ANNOTATIONS

Term:cAMP-dependent protein kinase inhibitor activity
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Accession:GO:0004862 term browser browse the term
Definition:Binds to and stops, prevents or reduces the activity of a cAMP-dependent protein kinase.
Synonyms:xref: reactome:R-HSA-180073 "DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function"


show annotations for term's descendants           Sort by:
cAMP-dependent protein kinase inhibitor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000068283 enables IEA GO_REF:0000002
GO_REF:0000118		 InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 Ensembl chr 6:44,214,352...44,214,555 JBrowse link
G LOC134479283 cAMP-dependent protein kinase inhibitor gamma-like enables IEA GO_REF:0000002
GO_REF:0000118		 InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118
G Pkia cAMP-dependent protein kinase inhibitor alpha enables ISO
IEA
IBA		 (PMID:21812984), (PMID:7905001)
GO_REF:0000002
GO_REF:0000118
GO_REF:0000033
(PMID:9218452)		 RGD
InterPro
TreeGrafter
GO_Central		 PMID:7905001 PMID:9218452 PMID:21812984 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:94,398,869...94,473,638
Ensembl chr 2:94,398,869...94,414,282 		JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta enables IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000104
GO_REF:0000118
GO_REF:0000033
(PMID:7905001)		 InterPro
UniProt
TreeGrafter
GO_Central
RGD		 PMID:7905001 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187 		JBrowse link
G Pkig cAMP-dependent protein kinase inhibitor gamma enables IMP
IBA
ISO		 GO_REF:0000033
(PMID:9218452)		 GO_Central
RGD		 PMID:9218452 PMID:15557275 GO_REF:0000033, RGD:1359036 NCBI chr 3:152,330,477...152,398,085
Ensembl chr 3:152,366,041...152,398,082 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 enables ISO (PMID:17255938) RGD PMID:17255938 NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,010,890...10,252,142 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha enables ISO
IEA
IBA		 (PMID:21812984)
GO_REF:0000107
GO_REF:0000033
(PMID:27803029), (PMID:32212257), (PMID:32735622)		 RGD
Ensembl
GO_Central		 PMID:21812984 PMID:27803029 PMID:32212257 PMID:32735622 GO_REF:0000033 GO_REF:0000107 NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041 		JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta enables ISO
IEA
IBA		 (PMID:21812984)
GO_REF:0000118
GO_REF:0000033		 RGD
TreeGrafter
GO_Central		 PMID:21812984 GO_REF:0000033 GO_REF:0000118 NCBI chr12:15,492,233...15,624,942
Ensembl chr12:15,511,801...15,624,942 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha enables ISO
IEA
IBA		 (PMID:21812984)
GO_REF:0000107
GO_REF:0000118
GO_REF:0000033		 RGD
Ensembl
TreeGrafter
GO_Central		 PMID:21812984 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628 		JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta enables ISO
IEA
IBA		 (PMID:21812984)
GO_REF:0000118
GO_REF:0000033		 RGD
TreeGrafter
GO_Central		 PMID:21812984 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933 		JBrowse link
G Smo smoothened, frizzled class receptor enables IEA
ISO		 GO_REF:0000107
(PMID:36202993)		 Ensembl
RGD		 PMID:36202993 GO_REF:0000107 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    molecular function regulator activity 2143
      enzyme regulator activity 1355
        kinase regulator activity 289
          protein kinase regulator activity 246
            cAMP-dependent protein kinase regulator activity 12
              cAMP-dependent protein kinase inhibitor activity 11
Path 2
Term Annotations click to browse term
  molecular_function 21010
    molecular function regulator activity 2143
      molecular function inhibitor activity 562
        enzyme inhibitor activity 426
          kinase inhibitor activity 81
            protein kinase inhibitor activity 75
              protein serine/threonine kinase inhibitor activity 39
                cAMP-dependent protein kinase inhibitor activity 11
paths to the root