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ONTOLOGY REPORT - ANNOTATIONS

Term:triglyceride biosynthetic process
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Accession:GO:0019432 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.
Synonyms:exact_synonym: triacylglycerol biosynthesis;   triacylglycerol biosynthetic process;   triglyceride anabolism;   triglyceride biosynthesis;   triglyceride formation;   triglyceride synthesis
 xref: MetaCyc:TRIGLSYN-PWY

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triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long chain family member 1 ISO RGD PMID:16466685 RGD:2312800 NCBI chrNW_004936554:4,425,518...4,484,853
Ensembl chrNW_004936554:4,425,495...4,484,887 		JBrowse link
G Acsl4 acyl-CoA synthetase long chain family member 4 ISO RGD PMID:16466685 RGD:2312800 NCBI chrNW_004936499:5,456,985...5,540,115
Ensembl chrNW_004936499:5,456,986...5,540,144 		JBrowse link
G Acsl6 acyl-CoA synthetase long chain family member 6 ISO RGD PMID:16466685 RGD:2312800 NCBI chrNW_004936647:3,153,586...3,208,935
Ensembl chrNW_004936647:3,153,485...3,213,582 		JBrowse link
G Agmo alkylglycerol monooxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936546:1,993,477...2,179,623
Ensembl chrNW_004936546:1,855,801...2,179,461 		JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936669:1,185,204...1,198,972
Ensembl chrNW_004936669:1,195,365...1,202,042 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:18458083) RGD
TreeGrafter
Ensembl
InterPro
MGI		 PMID:14596837 PMID:18458083 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1625586 NCBI chrNW_004936470:7,916,438...7,926,089
Ensembl chrNW_004936470:7,916,438...7,926,088 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14668353)
(PMID:11481335), (PMID:12077311)		 Ensembl
MGI
TreeGrafter		 PMID:11481335 PMID:12077311 PMID:14668353 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936498:4,514,212...4,544,523
Ensembl chrNW_004936498:4,514,184...4,544,527 		JBrowse link
G Gk glycerol kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936553:6,707,148...6,787,245 JBrowse link
G Gnpat glyceronephosphate O-acyltransferase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936484:19,414,094...19,434,929
Ensembl chrNW_004936484:19,410,956...19,434,929 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936486:2,754,753...2,823,600
Ensembl chrNW_004936486:2,754,751...2,823,665 		JBrowse link
G Gpat2 glycerol-3-phosphate acyltransferase 2, mitochondrial involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17689486) Ensembl
MGI
TreeGrafter		 PMID:17689486 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936744:183,679...194,448
Ensembl chrNW_004936744:183,882...193,661 		JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936738:1,107,725...1,166,697
Ensembl chrNW_004936738:1,108,822...1,166,913 		JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 NOT|involved_in ISO
IEA		 (PMID:18238778) UniProt
TreeGrafter
Ensembl		 PMID:18238778 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936785:967,871...1,007,761
Ensembl chrNW_004936785:966,295...1,007,747 		JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 involved_in ISO (MGI:6467683|PMID:20018982) UniProt PMID:20018982 MGI:6467683 NCBI chrNW_004936557:1,520,692...1,627,479
Ensembl chrNW_004936557:1,556,526...1,621,456 		JBrowse link
G Lpin1 lipin 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936532:7,596,279...7,654,139
Ensembl chrNW_004936532:7,605,965...7,652,573 		JBrowse link
G Lpin2 lipin 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936672:1,550,865...1,606,268
Ensembl chrNW_004936672:1,568,732...1,602,931 		JBrowse link
G Lpin3 lipin 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936561:430,491...443,307
Ensembl chrNW_004936561:431,866...443,307 		JBrowse link
G Lpl lipoprotein lipase ISO RGD PMID:11788374 RGD:70246 NCBI chrNW_004936555:4,084,099...4,108,219
Ensembl chrNW_004936555:4,084,099...4,108,365 		JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936569:4,625,981...4,665,930
Ensembl chrNW_004936569:4,625,867...4,662,861 		JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12576479) Ensembl
MGI
TreeGrafter		 PMID:12576479 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936498:4,464,453...4,482,237
Ensembl chrNW_004936498:4,464,427...4,481,509 		JBrowse link
G Mogat3 monoacylglycerol O-acyltransferase 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936543:1,082,916...1,085,904
Ensembl chrNW_004936543:1,082,785...1,086,979 		JBrowse link
G Pnpla3 patatin like phospholipase domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936718:1,620,034...1,638,315
Ensembl chrNW_004936718:1,619,948...1,638,317 		JBrowse link
G Tmem68 transmembrane protein 68 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936496:2,453,014...2,484,637
Ensembl chrNW_004936496:2,452,990...2,485,166 		JBrowse link
glycerol biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pck1 phosphoenolpyruvate carboxykinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11792850) Ensembl
MGI
TreeGrafter		 PMID:11792850 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936530:361,872...367,005
Ensembl chrNW_004936530:361,872...367,005 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2, mitochondrial involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936722:428,473...450,452
Ensembl chrNW_004936722:428,307...437,328 		JBrowse link
negative regulation of phosphatidate phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpin1 lipin 1 ISO RGD PMID:21715287 RGD:38599010 NCBI chrNW_004936532:7,596,279...7,654,139
Ensembl chrNW_004936532:7,605,965...7,652,573 		JBrowse link
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:29148806 RGD:15042869 NCBI chrNW_004936492:13,315,265...13,365,186
Ensembl chrNW_004936492:13,315,265...13,374,034 		JBrowse link
G Sik1 salt inducible kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936500:774,749...784,326
Ensembl chrNW_004936500:774,092...784,330 		JBrowse link
G Sirt1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:10,296,097...10,316,673
Ensembl chrNW_004936521:10,296,097...10,322,215 		JBrowse link
G Tmx1 thioredoxin related transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936495:14,432,971...14,447,380
Ensembl chrNW_004936495:14,431,137...14,447,476 		JBrowse link
positive regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl5 acyl-CoA synthetase long chain family member 5 ISO RGD PMID:16263710 RGD:2312807 NCBI chrNW_004936486:2,952,379...2,992,148
Ensembl chrNW_004936486:2,967,522...2,991,154 		JBrowse link
G Apoc3 apolipoprotein C3 ISO RGD PMID:23542898 RGD:10054091 NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603 		JBrowse link
G Cnep1r1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:3,163,275...3,176,210
Ensembl chrNW_004936475:3,162,995...3,176,669 		JBrowse link
G Ctdnep1 CTD nuclear envelope phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:537,131...543,341
Ensembl chrNW_004936595:536,297...543,071 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 ISO RGD PMID:23449193 RGD:10400846 NCBI chrNW_004936470:7,916,438...7,926,089
Ensembl chrNW_004936470:7,916,438...7,926,088 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chrNW_004936498:4,514,212...4,544,523
Ensembl chrNW_004936498:4,514,184...4,544,527 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial ISO RGD PMID:15598672 RGD:2313665 NCBI chrNW_004936486:2,754,753...2,823,600
Ensembl chrNW_004936486:2,754,751...2,823,665 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (MGI:3617276|PMID:16219662) UniProt PMID:16219662 MGI:3617276 NCBI chrNW_004936671:780,173...827,628
Ensembl chrNW_004936671:782,135...827,771 		JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:3,767,526...3,775,416
Ensembl chrNW_004936599:3,766,242...3,776,128 		JBrowse link
G Ldlr low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936659:1,259,405...1,300,545
Ensembl chrNW_004936659:1,259,369...1,302,294 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5474727|PMID:23209793) ARUK-UCL
Ensembl		 PMID:23209793 GO_REF:0000107 MGI:5474727 NCBI chrNW_004936474:21,790,807...21,803,336
Ensembl chrNW_004936474:21,790,747...21,803,360 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1 group H member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936889:223,137...229,968
Ensembl chrNW_004936889:223,101...229,990 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936562:1,937,665...1,946,680
Ensembl chrNW_004936562:1,937,667...1,946,669 		JBrowse link
G Plin5 perilipin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:2,629,762...2,637,303
Ensembl chrNW_004936588:2,629,762...2,636,983 		JBrowse link
G Rgn regucalcin ISO RGD PMID:16817230 RGD:9590221 NCBI chrNW_004936502:12,872,938...12,891,270
Ensembl chrNW_004936502:12,872,824...12,891,506 		JBrowse link
G Scarb1 scavenger receptor class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:530,828...555,098
Ensembl chrNW_004936558:530,828...552,892 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:3,426,807...3,451,259
Ensembl chrNW_004936596:3,427,874...3,449,489 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16046411) Ensembl
MGI		 PMID:16046411 GO_REF:0000107 NCBI chrNW_004936741:1,408,669...1,419,717
Ensembl chrNW_004936741:1,406,521...1,419,776 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:23260145) MGI PMID:23260145 NCBI chrNW_004936486:3,473,877...3,660,565
Ensembl chrNW_004936486:3,473,843...3,660,576 		JBrowse link
regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:10432298) UniProt PMID:10432298 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G Fitm2 fat storage inducing transmembrane protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936530:2,491,924...2,498,579
Ensembl chrNW_004936530:2,491,879...2,498,717 		JBrowse link
G Thrsp thyroid hormone responsive involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:6,622,007...6,624,961
Ensembl chrNW_004936498:6,622,004...6,624,961 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15975
    metabolic process 9645
      cellular metabolic process 7990
        cellular biosynthetic process 6365
          glycerolipid biosynthetic process 217
            acylglycerol biosynthetic process 58
              triglyceride biosynthetic process 48
                glycerol biosynthetic process from pyruvate 2
                negative regulation of triglyceride biosynthetic process + 5
                positive regulation of triglyceride biosynthetic process + 19
                regulation of triglyceride biosynthetic process + 27
Path 2
Term Annotations click to browse term
  biological_process 15975
    metabolic process 9645
      primary metabolic process 8435
        lipid metabolic process 1282
          cellular lipid metabolic process 962
            glycerolipid metabolic process 383
              glycerolipid biosynthetic process 217
                acylglycerol biosynthetic process 58
                  triglyceride biosynthetic process 48
                    glycerol biosynthetic process from pyruvate 2
                    negative regulation of triglyceride biosynthetic process + 5
                    positive regulation of triglyceride biosynthetic process + 19
                    regulation of triglyceride biosynthetic process + 27
paths to the root