Acsl4 (acyl-CoA synthetase long chain family member 4) - Rat Genome Database
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Gene: Acsl4 (acyl-CoA synthetase long chain family member 4) Ictidomys tridecemlineatus
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Symbol: Acsl4
Name: acyl-CoA synthetase long chain family member 4
RGD ID: 12557364
Description: ENCODES a protein that exhibits arachidonate-CoA ligase activity (ortholog); long-chain fatty acid-CoA ligase activity (ortholog); very long-chain fatty acid-CoA ligase activity (ortholog); INVOLVED IN dendritic spine development (ortholog); embryonic process involved in female pregnancy (ortholog); fatty acid metabolic process (ortholog); PARTICIPATES IN fatty acid beta degradation pathway; ASSOCIATED WITH Animal Disease Models (ortholog); autistic disorder (ortholog); Erythema (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); lipid droplet (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: acyl-CoA synthetase long-chain family member 4; long-chain-fatty-acid--CoA ligase 4
Orthologs:
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364995,456,985 - 5,540,115 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Acsl4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364995,456,985 - 5,540,115 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACSL4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX109,624,244 - 109,733,403 (-)EnsemblGRCh38hg38GRCh38
GRCh38X109,641,335 - 109,733,325 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X108,884,564 - 108,976,621 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X108,771,220 - 108,863,277 (-)NCBINCBI36hg18NCBI36
Build 34X108,690,710 - 108,782,764NCBI
CeleraX109,364,202 - 109,456,256 (-)NCBI
Cytogenetic MapXq23NCBI
HuRefX98,507,227 - 98,598,360 (-)NCBIHuRef
CHM1_1X108,795,825 - 108,887,899 (-)NCBICHM1_1
Acsl4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X141,100,989 - 141,173,792 (-)NCBI
GRCm38X142,317,993 - 142,390,802 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX142,317,993 - 142,390,535 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X138,752,536 - 138,825,078 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X137,564,361 - 137,636,903 (-)NCBImm8
CeleraX126,313,470 - 126,386,150 (-)NCBICelera
Cytogenetic MapXF2NCBI
Acsl4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X113,596,247 - 113,660,024 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX113,596,239 - 113,659,944 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X112,046,187 - 112,109,974 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X36,168,547 - 36,232,162 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X36,222,015 - 36,285,631 (+)NCBI
CeleraX105,356,949 - 105,420,560 (-)NCBICelera
Cytogenetic MapXq33NCBI
Acsl4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554906,143,833 - 6,228,452 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554906,143,833 - 6,228,395 (+)NCBIChiLan1.0ChiLan1.0
ACSL4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X109,219,030 - 109,311,055 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX109,206,964 - 109,310,914 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X98,731,109 - 98,841,067 (-)NCBIMhudiblu_PPA_v0panPan3
ACSL4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 EnsemblX82,866,823 - 82,916,789 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1X82,864,506 - 82,943,984 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
ACSL4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX89,760,865 - 89,837,678 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X89,760,863 - 89,838,103 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X105,375,895 - 105,452,684 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACSL4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X97,488,414 - 97,575,251 (-)NCBI
Acsl4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248036,272,954 - 6,372,815 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005323361   ⟹   XP_005323418
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049364995,456,985 - 5,540,115 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013357754   ⟹   XP_013213208
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049364995,456,985 - 5,540,115 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005323418 (Get FASTA)   NCBI Sequence Viewer  
  XP_013213208 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005323418   ⟸   XM_005323361
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013213208   ⟸   XM_013357754
- Peptide Label: isoform X1
- UniProtKB: I3M5T6 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
AMP-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000005275 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000004738 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000005286 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.12780 UniProtKB/TrEMBL
InterPro AMP-binding_CS UniProtKB/TrEMBL
  AMP-dep_Synth/Lig UniProtKB/TrEMBL
  AMP-dep_Synthh-like_sf UniProtKB/TrEMBL
NCBI Gene Acsl4 ENTREZGENE
Pfam AMP-binding UniProtKB/TrEMBL
PROSITE AMP_BINDING UniProtKB/TrEMBL
UniProt I3M5T6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-20 Acsl4  acyl-CoA synthetase long chain family member 4    acyl-CoA synthetase long-chain family member 4  Symbol and/or name change 5135510 APPROVED