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ONTOLOGY REPORT - ANNOTATIONS

Term:mRNA cleavage and polyadenylation specificity factor complex
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Accession:GO:0005847 term browser browse the term
Definition:A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
Synonyms:narrow_synonym: CPF complex;   CPSF complex
 related_synonym: CFII complex;   cleavage and polyadenylylation specificity factor activity


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mRNA cleavage and polyadenylation specificity factor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpsf1 cleavage and polyadenylation specific factor 1 part_of IBA
ISS
ISO		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr15:76,480,008...76,491,861
Ensembl chr15:76,480,003...76,491,791 		JBrowse link
G Cpsf2 cleavage and polyadenylation specific factor 2 part_of IDA
ISS
ISO
IBA		 (PMID:16115198) MGI
UniProt
GO_Central		 PMID:16115198 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr12:101,940,345...101,972,252
Ensembl chr12:101,942,247...101,972,683 		JBrowse link
G Cpsf3 cleavage and polyadenylation specificity factor 3 part_of IDA
ISO
ISS
IBA		 (PMID:16115198) MGI
GO_Central
UniProt		 PMID:16115198 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr12:21,336,298...21,365,057
Ensembl chr12:21,335,392...21,365,057 		JBrowse link
G Cpsf4 cleavage and polyadenylation specific factor 4 part_of IBA
ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 5:145,104,023...145,118,851
Ensembl chr 5:145,104,023...145,118,851 		JBrowse link
G Cpsf4l cleavage and polyadenylation specific factor 4-like part_of IBA GO_Central GO_REF:0000033 NCBI chr11:113,588,997...113,601,125
Ensembl chr11:113,588,998...113,600,843 		JBrowse link
G Cpsf6 cleavage and polyadenylation specific factor 6 part_of ISO
IBA		 GO_Central GO_REF:0000033 GO_REF:0000119 NCBI chr10:117,180,572...117,212,903
Ensembl chr10:117,180,578...117,215,920 		JBrowse link
G Cpsf7 cleavage and polyadenylation specific factor 7 part_of ISO
IEA
IBA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr19:10,502,594...10,525,099
Ensembl chr19:10,502,630...10,525,017 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 located_in
part_of		 ISO
ISS		 (PMID:18305108) UniProt
UniProt
GO_Central		 PMID:18305108 GO_REF:0000024 GO_REF:0000119 NCBI chr18:61,687,307...61,723,391
Ensembl chr18:61,688,345...61,723,132 		JBrowse link
G Cstf2 cleavage stimulation factor, 3' pre-RNA subunit 2 part_of ISS
ISO
IBA		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr  X:132,959,925...132,987,571
Ensembl chr  X:132,959,936...132,987,568 		JBrowse link
G Cstf2t cleavage stimulation factor, 3' pre-RNA subunit 2, tau part_of IBA GO_Central GO_REF:0000033 NCBI chr19:31,060,241...31,063,992
Ensembl chr19:31,060,237...31,064,469 		JBrowse link
G Fip1l1 factor interacting with PAPOLA and CPSF1 part_of IBA
IDA		 (PMID:19224921) GO_Central
MGI		 PMID:19224921 GO_REF:0000033 NCBI chr 5:74,695,774...74,759,451
Ensembl chr 5:74,696,110...74,759,461 		JBrowse link
G Marveld3 MARVEL (membrane-associating) domain containing 3 part_of IBA GO_Central GO_REF:0000033 NCBI chr 8:110,674,541...110,688,837
Ensembl chr 8:110,674,546...110,688,835 		JBrowse link
G Nudt21 nudix hydrolase 21 part_of ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 8:94,746,031...94,763,667
Ensembl chr 8:94,742,124...94,763,659 		JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha located_in
part_of		 ISO
IEA		 (PMID:18305108) UniProt
Ensembl
GO_Central		 PMID:18305108 GO_REF:0000107 GO_REF:0000119 NCBI chr 3:94,965,841...95,014,241
Ensembl chr 3:94,965,841...95,014,241 		JBrowse link
G Ssu72 Ssu72 RNA polymerase II CTD phosphatase homolog (yeast) part_of IBA GO_Central GO_REF:0000033 NCBI chr 4:155,789,272...155,818,336
Ensembl chr 4:155,789,257...155,818,336 		JBrowse link
G Sympk symplekin part_of IBA GO_Central GO_REF:0000033 NCBI chr 7:18,758,321...18,788,542
Ensembl chr 7:18,758,302...18,788,543 		JBrowse link
G Tut1 terminal uridylyl transferase 1, U6 snRNA-specific located_in
part_of		 ISO
ISS		 (PMID:18305108) UniProt
GO_Central
UniProt		 PMID:18305108 GO_REF:0000024 GO_REF:0000119 NCBI chr19:8,931,199...8,943,572
Ensembl chr19:8,931,211...8,943,574 		JBrowse link
G Wdr33 WD repeat domain 33 part_of IBA GO_Central GO_REF:0000033 NCBI chr18:31,937,079...32,042,040
Ensembl chr18:31,937,143...32,040,450 		JBrowse link
G Zc3h3 zinc finger CCCH type containing 3 part_of IDA (PMID:16115198) MGI PMID:16115198 NCBI chr15:75,626,279...75,713,772
Ensembl chr15:75,626,279...75,713,764 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 28566
    protein-containing complex 6101
      nuclear protein-containing complex 1294
        mRNA cleavage factor complex 24
          mRNA cleavage and polyadenylation specificity factor complex 19
Path 2
Term Annotations click to browse term
  cellular_component 28566
    cellular anatomical structure 19592
      organelle 13697
        membrane-bounded organelle 12698
          intracellular membrane-bounded organelle 12142
            nucleus 7539
              nuclear protein-containing complex 1294
                mRNA cleavage factor complex 24
                  mRNA cleavage and polyadenylation specificity factor complex 19
paths to the root