Pip5k1a (phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha) - Rat Genome Database

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Gene: Pip5k1a (phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha) Mus musculus
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Symbol: Pip5k1a
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
RGD ID: 1314562
MGI Page MGI
Description: Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity. Acts upstream of or within fibroblast migration and phosphatidylinositol biosynthetic process. Located in cytosol; nucleus; and ruffle membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase; 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha; 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase; phosphatidylinositol 4-phosphate 5-kinase type I alpha; phosphatidylinositol 4-phosphate 5-kinase type I beta; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; phosphatidylinositol-4-phosphate 5-kinase type I alpha; phosphatidylinositol-4-phosphate 5-kinase type I beta; phosphatidylinositol-4-phosphate 5-kinase type-1 alpha; Pi; PI4P5K-I[a]; PI4P5KIbeta; PIP5K1-alpha; Pip5k1b; PIP5KIalpha; Pipk5a; Pipk5b; ptdIns(4)P-5-kinase 1 alpha
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
NCBI Annotation Information: Note: This record was renamed from Pip5k1b to Pip5k1a to conform to the annotation of human. [03 Apr 2007]
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39394,965,841 - 95,014,241 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl394,965,841 - 95,014,241 (-)EnsemblGRCm39 Ensembl
GRCm38395,058,530 - 95,106,930 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl395,058,530 - 95,106,930 (-)EnsemblGRCm38mm10GRCm38
MGSCv37394,863,517 - 94,910,780 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36395,144,999 - 95,192,262 (-)NCBIMGSCv36mm8
Celera396,490,835 - 96,538,184 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
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Reference
Notes
Source
Original Reference(s)
Pip5k1aMouseautosomal dominant intellectual developmental disorder 60 with seizures  ISOPIP5K1A (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual developmental disorder 60 with seizuresClinVarPMID:25741868
Pip5k1aMouseDravet syndrome  ISOPIP5K1A (Homo sapiens)8554872ClinVar Annotator: match by term: Severe myoclonic epilepsy in infancyClinVarPMID:28492532
Pip5k1aMousegastrointestinal stromal tumor  ISOPIP5K1A (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
Pip5k1aMouseimmunodeficiency 42  ISOPIP5K1A (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal recessive mendelian susceptibility to mycobacterial diseases due to complete RORgamma receptor deficiencyClinVarPMID:28492532
Pip5k1aMouseMHC class II deficiency  ISOPIP5K1A (Homo sapiens)8554872ClinVar Annotator: match by term: MHC class II deficiencyClinVarPMID:28492532
Pip5k1aMouseparathyroid carcinoma  ISOPIP5K1A (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532
Pip5k1aMousesevere congenital neutropenia 3  ISOPIP5K1A (Homo sapiens)8554872ClinVar Annotator: match by term: Kostmann syndromeClinVarPMID:28492532
Pip5k1aMousesevere congenital neutropenia 5  ISOPIP5K1A (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital neutropenia-myelofibrosis-nephromegaly syndromeClinVarPMID:28492532
Object Symbol
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Evidence
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Original Reference(s)
Pip5k1aMouseExperimental Neoplasms  ISOPIP5K1A (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:34755307
Pip5k1aMouseLymphatic Metastasis  ISOPIP5K1A (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:34755307
Pip5k1aMouseNeoplasm Invasiveness  ISOPIP5K1A (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:34755307
Pip5k1aMouseurinary bladder cancer  ISOPIP5K1A (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:34755307

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Original Reference(s)
Pip5k1aMouse1,2-dimethylhydrazine increases expressionEXP 64804641 and 2-Dimethylhydrazine results in increased expression of PIP5K1A mRNACTDPMID:22206623
Pip5k1aMouse1-octadec-9-enoylglycero-3-phosphate multiple interactionsEXP 64804641-Butanol inhibits the reaction [lysophosphatidic acid results in increased activity of PIP5K1A protein] and DGKA protein promotes the reaction [lysophosphatidic acid results in increased activity of PIP5K1A protein]CTDPMID:10913605
Pip5k1aMouse1-octadec-9-enoylglycero-3-phosphate increases activityEXP 6480464lysophosphatidic acid results in increased activity of PIP5K1A proteinCTDPMID:10913605
Pip5k1aMouse17beta-estradiol multiple interactionsISOPIP5K1A (Homo sapiens)6480464ESR1 protein affects the reaction [Estradiol results in increased expression of PIP5K1A mRNA]CTDPMID:15223131
Pip5k1aMouse17beta-estradiol increases expressionISOPIP5K1A (Homo sapiens)6480464Estradiol results in increased expression of PIP5K1A mRNACTDPMID:15223131 and PMID:19167446
Pip5k1aMouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of PIP5K1A mRNACTDPMID:21570461
Pip5k1aMouse2-hydroxypropanoic acid increases expressionISOPIP5K1A (Homo sapiens)6480464Lactic Acid results in increased expression of PIP5K1A mRNACTDPMID:30851411
Pip5k1aMouse3,4-methylenedioxymethamphetamine increases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PIP5K1A mRNACTDPMID:26251327
Pip5k1aMouse3,4-methylenedioxymethamphetamine increases methylationEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased methylation of PIP5K1A promoterCTDPMID:26251327
Pip5k1aMouse4,4'-sulfonyldiphenol multiple interactionsISOPip5k1a (Rattus norvegicus)6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PIP5K1A mRNACTDPMID:36041667
Pip5k1aMouse5-azacytidine decreases expressionISOPIP5K1A (Homo sapiens)6480464Azacitidine results in decreased expression of PIP5K1A mRNACTDPMID:19194470
Pip5k1aMouseacrylamide decreases expressionISOPip5k1a (Rattus norvegicus)6480464Acrylamide results in decreased expression of PIP5K1A mRNACTDPMID:28959563
Pip5k1aMouseallethrin multiple interactionsISOPip5k1a (Rattus norvegicus)6480464[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in decreased expression of PIP5K1A proteinCTDPMID:34896426
Pip5k1aMouseamiodarone increases expressionISOPIP5K1A (Homo sapiens)6480464Amiodarone results in increased expression of PIP5K1A mRNACTDPMID:19774075
Pip5k1aMousearsane affects methylationISOPIP5K1A (Homo sapiens)6480464Arsenic affects the methylation of PIP5K1A geneCTDPMID:25304211
Pip5k1aMousearsane multiple interactionsISOPIP5K1A (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PIP5K1A mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of PIP5K1A mRNACTDPMID:39836092
Pip5k1aMousearsenic atom affects methylationISOPIP5K1A (Homo sapiens)6480464Arsenic affects the methylation of PIP5K1A geneCTDPMID:25304211
Pip5k1aMousearsenic atom multiple interactionsISOPIP5K1A (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of PIP5K1A mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of PIP5K1A mRNACTDPMID:39836092
Pip5k1aMousebenzo[a]pyrene increases expressionEXP 6480464Benzo(a)pyrene results in increased expression of PIP5K1A mRNACTDPMID:27195522
Pip5k1aMousebenzo[a]pyrene increases methylationISOPIP5K1A (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of PIP5K1A 5' UTRCTDPMID:27901495

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Biological Process
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Object Symbol
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Original Reference(s)
Pip5k1aMouseactin cytoskeleton organization involved_inISSUniProtKB:Q997552290270 UniProtGO_REF:0000024
Pip5k1aMouseactin cytoskeleton organization involved_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMouseactivation of GTPase activity involved_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMouseactivation of GTPase activity involved_inISSUniProtKB:Q997552290270 UniProtGO_REF:0000024
Pip5k1aMousecell chemotaxis involved_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMousecell chemotaxis involved_inISSUniProtKB:Q997552290270 UniProtGO_REF:0000024
Pip5k1aMousefibroblast migration acts_upstream_of_or_withinIMP 2290270 PMID:15870270MGIPMID:15870270
Pip5k1aMousefocal adhesion assembly involved_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMousefocal adhesion assembly involved_inISSUniProtKB:Q997552290270 UniProtGO_REF:0000024
Pip5k1aMousephosphatidylinositol biosynthetic process acts_upstream_of_or_withinIGIMGI:12982242290270 PMID:20622009MGIPMID:20622009
Pip5k1aMousephosphatidylinositol metabolic process acts_upstream_of_or_withinIDA 2290270 PMID:8798574MGIPMID:8798574
Pip5k1aMousephosphatidylinositol phosphate biosynthetic process involved_inIBAPANTHER:PTN000557041 more ...2290270 GO_CentralGO_REF:0000033
Pip5k1aMousephospholipid biosynthetic process involved_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMouseprotein localization to plasma membrane involved_inISSUniProtKB:Q997552290270 UniProtGO_REF:0000024
Pip5k1aMouseprotein localization to plasma membrane involved_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMouseruffle assembly involved_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMouseruffle assembly involved_inISSUniProtKB:Q997552290270 UniProtGO_REF:0000024
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Cellular Component
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Object Symbol
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Original Reference(s)
Pip5k1aMousecytosol located_inIDA 2290270 PMID:20622009MGIPMID:20622009
Pip5k1aMousecytosol located_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMouselamellipodium located_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMouselamellipodium located_inIEAUniProtKB-SubCell:SL-02912290270 UniProtGO_REF:0000044
Pip5k1aMousemRNA cleavage and polyadenylation specificity factor complex part_ofISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMousemRNA cleavage and polyadenylation specificity factor complex part_ofIEAUniProtKB:Q99755 and ensembl:ENSP000003578832290270 EnsemblGO_REF:0000107
Pip5k1aMousemRNA cleavage and polyadenylation specificity factor complex located_inISOPIP5K1A (Homo sapiens)9068941 PMID:18305108UniProtPMID:18305108
Pip5k1aMousenuclear speck located_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMousenuclear speck located_inISSUniProtKB:Q997552290270 UniProtGO_REF:0000024
Pip5k1aMousenucleoplasm located_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMousenucleus located_inIDA 2290270 PMID:15870270MGIPMID:15870270
Pip5k1aMousenucleus located_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMouseplasma membrane located_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMouseplasma membrane is_active_inIBAPANTHER:PTN000557041 more ...2290270 GO_CentralGO_REF:0000033
Pip5k1aMouseplasma membrane located_inISSUniProtKB:Q997552290270 UniProtGO_REF:0000024
Pip5k1aMouseruffle membrane located_inISOUniProtKB:Q997552290270 GO_CentralGO_REF:0000119
Pip5k1aMouseruffle membrane located_inIDA 2290270 PMID:15870270MGIPMID:15870270
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Molecular Function
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Imported Annotations - SMPDB

Object Symbol
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Original Reference(s)
Pip5k1aMousephosphoinositide metabolic pathway  ISOPIP5K1A (Homo sapiens)10402751 SMPDBSMP:00463

Imported Annotations - KEGG (archival)

Object Symbol
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Original Reference(s)
Pip5k1aMouseendocytosis pathway  IEA 6907045 KEGGmmu:04144
Pip5k1aMouseinositol phosphate metabolic pathway  IEA 6907045 KEGGmmu:00562
Pip5k1aMousephosphatidylinositol 3-kinase signaling pathway  IEA 6907045 KEGGmmu:04070

Imported Annotations - PID (archival)

Object Symbol
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Original Reference(s)
Pip5k1aMouseArf family mediated signaling pathway  ISOPIP5K1A (Homo sapiens)6484113 PIDPID:200195
Pip5k1aMouseE-cadherin signaling pathway  ISOPIP5K1A (Homo sapiens)6484113 PIDPID:200147

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#
Reference Title
Reference Citation
1. Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family. Ishihara H, etal., J Biol Chem 1998 Apr 10;273(15):8741-8.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
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PMID:8798574   PMID:9372970   PMID:10187762   PMID:10349636   PMID:10679324   PMID:10747863   PMID:10922068   PMID:11032811   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11252174  
PMID:11891857   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:14681219   PMID:14681479   PMID:14701839   PMID:15018809   PMID:15123724   PMID:15489334   PMID:15728183  
PMID:15782199   PMID:15870270   PMID:16141072   PMID:16141073   PMID:17940289   PMID:18188447   PMID:18772378   PMID:18799693   PMID:18981107   PMID:19116346   PMID:19153220   PMID:19587446  
PMID:20622009   PMID:20841379   PMID:21267068   PMID:21270258   PMID:21873635   PMID:22321832   PMID:22976293   PMID:23300084   PMID:23342003   PMID:24819416   PMID:24853942   PMID:27739494  
PMID:28711717   PMID:29426367   PMID:30550785   PMID:32325033   PMID:32560809   PMID:34624591  



Pip5k1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39394,965,841 - 95,014,241 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl394,965,841 - 95,014,241 (-)EnsemblGRCm39 Ensembl
GRCm38395,058,530 - 95,106,930 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl395,058,530 - 95,106,930 (-)EnsemblGRCm38mm10GRCm38
MGSCv37394,863,517 - 94,910,780 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36395,144,999 - 95,192,262 (-)NCBIMGSCv36mm8
Celera396,490,835 - 96,538,184 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.74NCBI
PIP5K1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381151,195,419 - 151,249,531 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1151,197,949 - 151,249,536 (+)EnsemblGRCh38hg38GRCh38
GRCh371151,171,028 - 151,222,007 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361149,437,696 - 149,488,629 (+)NCBINCBI36Build 36hg18NCBI36
Build 341147,984,144 - 148,035,078NCBI
Celera1124,286,312 - 124,337,297 (+)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1122,549,129 - 122,599,938 (+)NCBIHuRef
CHM1_11152,566,349 - 152,617,334 (+)NCBICHM1_1
T2T-CHM13v2.01150,319,124 - 150,373,243 (+)NCBIT2T-CHM13v2.0
Pip5k1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82185,317,319 - 185,361,859 (-)NCBIGRCr8
mRatBN7.22182,628,299 - 182,671,584 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2182,628,300 - 182,671,598 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2190,292,988 - 190,336,170 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02188,089,077 - 188,132,194 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02182,925,465 - 182,968,650 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02196,227,669 - 196,270,949 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2196,227,670 - 196,270,826 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02215,722,370 - 215,765,396 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42189,962,527 - 190,005,684 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12189,923,204 - 189,966,433 (-)NCBI
Celera2175,165,145 - 175,208,290 (-)NCBICelera
Cytogenetic Map2q34NCBI
Pip5k1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955588555,821 - 605,723 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955588555,818 - 605,459 (+)NCBIChiLan1.0ChiLan1.0
PIP5K1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,584,132 - 98,635,394 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1198,335,345 - 98,386,612 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01126,547,793 - 126,598,618 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11130,195,974 - 130,246,198 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1130,195,974 - 130,246,198 (+)Ensemblpanpan1.1panPan2
PIP5K1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11760,257,017 - 60,295,866 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1760,257,332 - 60,295,866 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1759,700,905 - 59,739,406 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01761,273,137 - 61,312,006 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1761,273,153 - 61,312,003 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11760,102,170 - 60,140,685 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01760,187,481 - 60,226,180 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01760,915,268 - 60,954,258 (+)NCBIUU_Cfam_GSD_1.0
Pip5k1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505822,369,145 - 22,417,998 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365801,399,954 - 1,446,769 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365801,399,492 - 1,448,398 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIP5K1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl498,012,945 - 98,056,815 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1498,012,941 - 98,062,166 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24107,265,724 - 107,314,945 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIP5K1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12012,439,726 - 12,490,331 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603812,017,486 - 12,069,455 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pip5k1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477218,616,121 - 18,658,286 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477218,616,095 - 18,658,016 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Pip5k1a
2509 total Variants

Predicted Target Of
Summary Value
Count of predictions:2833
Count of miRNA genes:540
Interacting mature miRNAs:635
Transcripts:ENSMUST00000005768, ENSMUST00000107229, ENSMUST00000107231, ENSMUST00000107232, ENSMUST00000107233, ENSMUST00000107236, ENSMUST00000151335
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 42 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366046658100046795Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382147043116147184Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383463991117464137Mouse
1301398Rapop3_mradiation-induced apoptosis 3 (mouse)Not determined390511217100464137Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
14746984Manh54_mmandible shape 54 (mouse)385289152119289152Mouse

1 to 10 of 42 rows
D17S610  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37394,906,640 - 94,906,854UniSTSGRCm37
Celera396,534,034 - 96,534,248UniSTS
Pip5k1a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3F2.1UniSTS
cM Map3 UniSTS
D86177  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38395,059,664 - 95,059,781UniSTSGRCm38
MGSCv37394,863,586 - 94,863,703UniSTSGRCm37
Celera396,490,904 - 96,491,021UniSTS
Cytogenetic Map3F2.1UniSTS
Whitehead/MRC_RH31081.54UniSTS
D3Umi8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38395,100,039 - 95,100,161UniSTSGRCm38
MGSCv37394,903,961 - 94,904,083UniSTSGRCm37
Celera396,531,349 - 96,531,481UniSTS
Cytogenetic Map3F2.1UniSTS
cM Map3 UniSTS






1 to 25 of 25 rows
RefSeq Transcripts NM_001293707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004941296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_375498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_375499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC087062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC131769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK098097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D86177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 25 of 25 rows

Ensembl Acc Id: ENSMUST00000005768   ⟹   ENSMUSP00000005768
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl394,965,880 - 95,014,090 (-)Ensembl
GRCm38.p6 Ensembl395,058,569 - 95,106,779 (-)Ensembl
Ensembl Acc Id: ENSMUST00000107229
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl395,004,354 - 95,014,134 (-)Ensembl
GRCm38.p6 Ensembl395,097,043 - 95,106,823 (-)Ensembl
Ensembl Acc Id: ENSMUST00000107231
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl394,978,137 - 94,985,827 (-)Ensembl
GRCm38.p6 Ensembl395,070,826 - 95,078,516 (-)Ensembl
Ensembl Acc Id: ENSMUST00000107232   ⟹   ENSMUSP00000102851
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl394,965,856 - 95,014,167 (-)Ensembl
GRCm38.p6 Ensembl395,058,545 - 95,106,856 (-)Ensembl
Ensembl Acc Id: ENSMUST00000107233   ⟹   ENSMUSP00000102852
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl394,965,854 - 95,014,241 (-)Ensembl
GRCm38.p6 Ensembl395,058,543 - 95,106,930 (-)Ensembl
Ensembl Acc Id: ENSMUST00000107236   ⟹   ENSMUSP00000102855
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl394,965,841 - 95,014,186 (-)Ensembl
GRCm38.p6 Ensembl395,058,530 - 95,106,875 (-)Ensembl
Ensembl Acc Id: ENSMUST00000151335
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl394,985,416 - 94,990,543 (-)Ensembl
GRCm38.p6 Ensembl395,078,105 - 95,083,232 (-)Ensembl
RefSeq Acc Id: NM_001293707   ⟹   NP_001280636
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39394,965,841 - 95,014,241 (-)NCBI
GRCm38395,058,530 - 95,106,930 (-)NCBI
Celera396,489,772 - 96,538,256 (-)NCBI
Sequence:
RefSeq Acc Id: NM_008847   ⟹   NP_032873
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39394,965,841 - 95,014,241 (-)NCBI
GRCm38395,058,530 - 95,106,930 (-)NCBI
MGSCv37394,863,517 - 94,910,780 (-)RGD
Celera396,489,772 - 96,538,256 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036162936   ⟹   XP_036018829
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39394,965,875 - 95,014,235 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162937   ⟹   XP_036018830
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39394,965,875 - 95,014,235 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162938   ⟹   XP_036018831
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39394,965,875 - 94,991,449 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162939   ⟹   XP_036018832
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39394,965,875 - 95,014,235 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004941296
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39394,965,875 - 95,014,235 (-)NCBI
Sequence:
RefSeq Acc Id: XR_375498
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39394,965,875 - 95,014,236 (-)NCBI
GRCm38395,058,551 - 95,106,925 (-)NCBI
Sequence:
RefSeq Acc Id: XR_375499
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39394,965,875 - 95,014,235 (-)NCBI
GRCm38395,058,551 - 95,106,924 (-)NCBI
Sequence:
1 to 5 of 10 rows
1 to 5 of 10 rows
RefSeq Acc Id: NP_032873   ⟸   NM_008847
- Peptide Label: isoform 2
- UniProtKB: Q8K0D3 (UniProtKB/Swiss-Prot),   Q3U917 (UniProtKB/Swiss-Prot),   F8WIX5 (UniProtKB/Swiss-Prot),   Q99L80 (UniProtKB/Swiss-Prot),   P70182 (UniProtKB/Swiss-Prot),   F8WI18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001280636   ⟸   NM_001293707
- Peptide Label: isoform 1
- UniProtKB: F8WI18 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000102852   ⟸   ENSMUST00000107233
Ensembl Acc Id: ENSMUSP00000102851   ⟸   ENSMUST00000107232
Ensembl Acc Id: ENSMUSP00000102855   ⟸   ENSMUST00000107236
PIPK

Name Modeler Protein Id AA Range Protein Structure
AF-P70182-F1-model_v2 AlphaFold P70182 1-546 view protein structure

RGD ID:6834246
Promoter ID:MM_KWN:35253
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000005768,   ENSMUST00000107232,   ENSMUST00000107233,   ENSMUST00000107235,   OTTMUST00000047069,   OTTMUST00000047071,   OTTMUST00000055692,   UC008QHZ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36394,910,649 - 94,911,149 (-)MPROMDB
RGD ID:6881534
Promoter ID:EPDNEW_M4218
Type:initiation region
Name:Pip5k1a_1
Description:Mus musculus phosphatidylinositol-4-phosphate 5-kinase, type1 alpha , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38395,106,867 - 95,106,927EPDNEW


1 to 33 of 33 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000028126 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000107232 ENTREZGENE
  ENSMUST00000107233 ENTREZGENE
  ENSMUST00000107233.9 UniProtKB/Swiss-Prot
  ENSMUST00000107236 ENTREZGENE
  ENSMUST00000107236.9 UniProtKB/Swiss-Prot
Gene3D-CATH 2-Layer Sandwich UniProtKB/Swiss-Prot
  3.30.800.10 UniProtKB/Swiss-Prot
InterPro PInositol-4-P-4/5-kinase_C_sf UniProtKB/Swiss-Prot
  PInositol-4-P-5-kinase UniProtKB/Swiss-Prot
  PInositol-4-P-5-kinase_core UniProtKB/Swiss-Prot
  PInositol-4-P-5-kinase_N UniProtKB/Swiss-Prot
KEGG Report mmu:18720 UniProtKB/Swiss-Prot
MGD MGI:107929 ENTREZGENE
NCBI Gene 18720 ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE TYPE-1 ALPHA UniProtKB/Swiss-Prot
  PTHR23086 UniProtKB/Swiss-Prot
Pfam PIP5K UniProtKB/Swiss-Prot
PhenoGen Pip5k1a PhenoGen
PROSITE PIPK UniProtKB/Swiss-Prot
SMART PIPKc UniProtKB/Swiss-Prot
Superfamily-SCOP SAICAR synthase-like UniProtKB/Swiss-Prot
UniProt D3YUY3 ENTREZGENE, UniProtKB/TrEMBL
  F8WI18 ENTREZGENE, UniProtKB/TrEMBL
  F8WIX5 ENTREZGENE
  P70182 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3U917 ENTREZGENE
  Q8K0D3 ENTREZGENE
  Q99L80 ENTREZGENE
UniProt Secondary F8WIX5 UniProtKB/Swiss-Prot
  Q3U917 UniProtKB/Swiss-Prot
  Q8K0D3 UniProtKB/Swiss-Prot
  Q99L80 UniProtKB/Swiss-Prot
1 to 33 of 33 rows